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4. Does adjunctive endoscopic biliary drainage improve outcomes beyond glucocorticoids alone in IgG4-related pancreatobiliary disease?
作者: Zinan Zhang.;Yanbin Wei.;Jiafei Peng.;Yan Zhao.;Xin Yao.;Ye Zong.
来源: BMC Gastroenterol. 2025年25卷1期789页
Immunoglobulin G4 (IgG4)-related pancreatobiliary disease typically manifests as obstructive jaundice, complicating therapeutic choices. Glucocorticoids (GCs) are the primary treatment with many challenges, including high recurrence rates and patient tolerance variability. Endoscopic biliary drainage (EBD) is used to alleviate obstruction, but its role during treatment in IgG4-related pancreatobiliary disease is still contested. There remains a paucity of research comparing the potential benefits of combination therapy with GCs and EBD versus GCs monotherapy.
5. Ustekinumab enhances intestinal stenosis resolution by modulating fibrotic pathways in crohn's disease: a retrospective single-center study with translational analysis.
作者: Rieko Nakata.;Shuhei Hosomi.;Yumie Kobayashi.;Yu Nishida.;Hirotsugu Maruyama.;Masaki Ominami.;Yuji Nadatani.;Shusei Fukunaga.;Koji Otani.;Noriko Kamata.;Fumio Tanaka.;Tatsunari Fukuoka.;Kiyoshi Maeda.;Yasuhiro Fujiwara.
来源: BMC Gastroenterol. 2025年25卷1期785页
Few studies have evaluated the impact of biologic therapy on endoscopic findings and stenoses of small intestinal lesions in Crohn's disease (CD). This study aimed to compare the endoscopic effectiveness and stenotic changes induced by anti-tumor necrosis factor inhibitors (anti-TNF) and ustekinumab (UST) in patients with CD, along with histological and molecular comparisons of stenosis between the groups.
6. Effects of enhanced recovery after surgery nursing on patients undergoing laparoscopic colectomy: a systematic review and meta-analysis.
This study aimed to systematically evaluate the effects of Enhanced Recovery After Surgery (ERAS) nursing protocols on patients undergoing laparoscopic colectomy.
7. Gestational age-dependent clinical characteristics of necrotizing enterocolitis-associated intestinal perforation: a 10-year cohort study.
作者: Hong Wei.;Weihong Yue.;Gege Liu.;Feng Chen.;Xia Liu.;Ya Hu.
来源: BMC Gastroenterol. 2025年25卷1期787页
To delineate gestational age (GA)-dependent pathophysiology of necrotizing enterocolitis-associated intestinal perforation (NEC-IP) and establish precision management protocols.
8. Association between the blood urea nitrogen-albumin ratio and mortality in critically ill patients with gastrointestinal bleeding: a retrospective cohort study.
作者: Xingyi Yang.;Mengyuan Chen.;Mengyin Zhu.;Yiling Ying.;Lang Gao.;Lihong Lv.;Xiaoxiao Wang.;Xiangshu Yuan.
来源: BMC Gastroenterol. 2025年25卷1期786页
Acute gastrointestinal bleeding (GIB) represents a life-threatening medical emergency. This study investigates the prognostic utility of the Blood Urea Nitrogen-to-albumin ratio (BAR) in patients with GIB.
9. Linked color imaging for detection and characterization of gastrointestinal neuroendocrine tumors.
作者: Xin Pu.;Yang Xu.;Xueting Zhang.;Zijin Yin.;Yan Liu.;Min Min.
来源: BMC Gastroenterol. 2025年25卷1期784页
The endoscopic detection of gastrointestinal neuroendocrine tumors (GI-NETs) remains clinically challenging. Linked color imaging (LCI), which enhances color contrast, may improve the identification of tumorous lesions. This study aims to evaluate the endoscopic characteristics of GI-NETs using LCI in comparison with white light imaging (WLI).
10. Efficacy of N-Acetylcysteine in preventing post-endoscopic retrograde cholangiopancreatography pancreatitis: a systematic review and meta-analysis.
作者: Ahmad Hormati.;Asma Mousavi.;Shayan Shojaei.;Atie Moghtadaei.;Sanaz Bordbar.;Hediyeh Alemi.;Amir Kasaeian.;Sadaf Sepanlou.
来源: BMC Gastroenterol. 2025年25卷1期783页
Endoscopic retrograde cholangiopancreatography (ERCP) is a widely utilized procedure for diagnosing and treating biliary and pancreatic disorders. However, it carries a risk of post-ERCP pancreatitis (PEP). N-Acetylcysteine (NAC) has been proposed as a potential prophylactic agent due to its antioxidant properties, yet its efficacy remains debated. This systematic review and meta-analysis aimed to evaluate the effectiveness of NAC in preventing PEP in patients undergoing ERCP.
11. Autoimmune gastritis: clinical and histological study in a Peruvian population.
作者: Fernando Arevalo.;Soledad Rayme.;Romy Rolando.;Rocío Ramírez.;Grace Rodas.;Jaime Fustamante.;Eduardo Monge.;Pedro Montes.;Julio Maraví.
来源: BMC Gastroenterol. 2025年25卷1期780页
The diagnosis of autoimmune gastritis poses significant challenges, particularly in resource-limited settings where access to serological tests is restricted. This study aimed to evaluate the histological, endoscopic, and serological features of patients diagnosed with autoimmune gastritis in our population.
12. A novel model of dual-network composite hydrogels for application in endoscopic submucosal dissection.
作者: Fei Zhao.;YunFang Bai.;JunJie Wu.;ZhiHao Zhu.;JinLei Mao.;Aikebaier Aili.;HongRun Gu.;ShiJie Yu.;ZhiFei Wang.
来源: BMC Gastroenterol. 2025年25卷1期781页
Endoscopic submucosal dissection (ESD) is a critical technique for treating early-stage gastrointestinal tumors, requiring precise operational skills. Traditional training methods, however, face challenges such as high costs, ethical concerns, and sustainability issues. This study aims to design a novel training model based on dual-network composite hydrogel (DNH) (Jing, et al, Polymers 11:952,2019) to simulate the multilayered structure of gastric tissue, providing a more realistic and effective training environment.
13. Neutrophil percentage-to-albumin ratio for preoperative risk stratification of complicated appendicitis in children: a retrospective study.
Preoperative risk assessment of complicated appendicitis in children holds substantial clinical importance. This study aimed to evaluate the association between the neutrophil percentage-to-albumin ratio (NPAR) and the occurrence of complicated appendicitis in pediatric patients.
14. Analysis of exercise behavior and influencing factors in patients with inflammatory bowel disease during remission and mild disease activity.
作者: Yuan Xue.;Yajun Sun.;Jiajia Wu.;Bo Chen.;Jing Wang.;Bingqing Lu.
来源: BMC Gastroenterol. 2025年25卷1期779页
This study aimed to investigate the distribution of exercise stages and exercise preference among patients with Inflammatory Bowel Disease in remission or with mild disease activity and explore their influencing factors.
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