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1. Effectiveness and Tolerability of Pharmacologic Prophylaxis for Chronic Migraine : A Systematic Review of Randomized Controlled Trials.
作者: Malahat Khalili.;Faraidoon Haghdoost.;Amin Liaghatdar.;Kian Torabiardakani.;Fatemeh Mahdian.;Tal Levit.;Sara Moradi.;Ehsan Hedayati.;Farzaneh Ahmadi.;Sahar Khademioore.;Tariq Atkin-Jones.;Ahmad Sofi-Mahmudi.;Vivek Patil.;Fatemeh Mirzayeh Fashami.;Soheil Mehmandoost.;Harjind S Kahlon.;Rachel J Couban.;Kameshwar Prasad.;Seyed-Mohammad Fereshtehnejad.;Norman Buckley.;Jason W Busse.;Behnam Sadeghirad.
来源: Ann Intern Med. 2026年
Migraine headaches are considered chronic when they occur on 15 or more days per month. Newer medications are available for prevention.
2. Effect of Incretin-Based and Nonpharmacologic Weight Loss on Body Composition : A Systematic Review.
作者: John A Batsis.;Alessandro Gavras.;Danae C Gross.;C Ray Cheever.;Bruna R Da Silva.;Luiz Fernando Meira Filho.;Emily P Jones.;Dakota Batchek.;Simone Khandpekar.;Rohan Patel.;Bilal Awkal.;Annamarie Pape.;Marianne Bahna.;Mauro Zamboni.;Carla M Prado.
来源: Ann Intern Med. 2026年
Incretin-based therapies induce substantial weight loss and are widely prescribed; disproportionate losses in fat-free mass (FFM) and skeletal muscle are a concern.
3. Prevention of Recurrent Nephrolithiasis in Adults and Children : A Systematic Review.
作者: Gary N Asher.;Davis P Viprakasit.;Shannon E Aymes.;Jay B Lusk.;Sherry Ross.;Claire Baker.;Caroline Rains.;Sarah T Wright.;Leila C Kahwati.
来源: Ann Intern Med. 2026年179卷5期696-707页
Recurrent kidney stones are unpleasant and may lead to kidney damage, sepsis, or invasive procedures.
5. Care of Bereaved Persons : A Systematic Review.
作者: Sangeeta Ahluwalia.;Julia Bandini.;Margaret Maglione.;Jeremy Miles.;Kelsey O'Hollaren.;Diana Zhang.;Manasi Yedavalli.;Sachi Yagyu.;Aneesa Motala.;Susanne Hempel.
来源: Ann Intern Med. 2026年179卷4期535-547页
Bereavement after the death of someone close is universal, and clinicians may be uncertain if or what interventions may be beneficial.
6. The Prevalence and Characteristics of Difficult Patient Encounters : A Systematic Review and Meta-analysis.
作者: Jeffrey L Jackson.;Akira Kuriyama.;Jeff Whittle.;Anthony Davis-Maxwell.;Michelle Thompson.;Mary G Murphy.;Suma Gondi.;Kristen Brennan.;Cory Ganshert.;Kathlyn E Fletcher.
来源: Ann Intern Med. 2026年179卷3期382-393页
Patients are sometimes experienced as difficult by their providers.
9. Effect of Interventions Aimed at Reducing or Modifying Saturated Fat Intake on Cholesterol, Mortality, and Major Cardiovascular Events : A Risk Stratified Systematic Review of Randomized Trials.
作者: Jeremy P Steen.;Kevin C Klatt.;Yaping Chang.;Gordon H Guyatt.;Hongfei Zhu.;Mateusz J Swierz.;Dawid Storman.;Mingyao Sun.;Yunli Zhao.;Long Ge.;Lehana Thabane.;Nirjhar R Ghosh.;Giorgio Karam.;Pablo Alonso-Coello.;Malgorzata M Bala.;Bradley C Johnston.
来源: Ann Intern Med. 2026年179卷2期242-255页
Debates about optimal saturated fat advice continue.
10. Efficacy and Safety of Bisphosphonates for Complex Regional Pain Syndrome : A Systematic Review and Meta-analysis.
作者: Michael C Ferraro.;Neil E O'Connell.;Andreas Goebel.;Ruaraidh Hill.;Ffion Curtis.;Jack Wilkinson.;Jacqueline R Center.;Sylvia M Gustin.;Aidan G Cashin.;James H McAuley.
来源: Ann Intern Med. 2026年179卷2期256-269页
Clinical guidelines recommend bisphosphonates for complex regional pain syndrome (CRPS) despite limited evidence of efficacy.
13. Risk for Cancer With Glucagon-Like Peptide-1 Receptor Agonists and Dual Agonists : A Systematic Review and Meta-analysis.
作者: Albert Ko.;Yu-Cheng Chang.;Furkan Bahar.;Tsu Hsien Wang.;Nutchapon Xanthavanij.;Chun-Chiao Yu.;Rebecca Jen-Ling Hsieh.;Xin Ya See.;Shao-Wei Lo.;Junmin Song.;Yuan Ping Hsia.;Cho-Hung Chiang.;Xiaocao Xu.;Shuwen Lin.;Cho-Han Chiang.
来源: Ann Intern Med. 2026年179卷2期216-229页
Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are used for type 2 diabetes mellitus (T2DM) and overweight or obesity, but their association with cancer is unclear.
14. Systemic Corticosteroids, Mortality, and Infections in Pneumonia and Acute Respiratory Distress Syndrome : A Systematic Review and Meta-analysis.
作者: Alice Soumare.;Thomas Kapfer.;Thomas Botrel.;Leslie Adda.;Maxime Renaux.;Pierre-Louis Blot.;Jean-Michel Constantin.;Arthur James.;Rayan Braïk.
来源: Ann Intern Med. 2026年179卷1期67-80页
The benefit-risk profile of systemic corticosteroids in non-COVID-19 pneumonia and acute respiratory distress syndrome (ARDS) remains debated.
16. Web Exclusive. Annals Video Summary - Efficacy of Individual-Level Interventions to Mitigate the Risk for Burnout Among Health Care Professionals: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
来源: Ann Intern Med. 2026年179卷1期e2504275VS页
17. Comparative Effectiveness and Harm of Seasonal Influenza Vaccines in Adults Who Are Not Pregnant or Immunocompromised: A Rapid Review for the American College of Physicians.
作者: Andreea I Dobrescu.;Amin Sharifan.;Isolde Sommer.;Camilla I A Neubauer-Bruckner.;Arianna Gadinger.;Irma Klerings.;Claus Nowak.;Gerald Gartlehner.
来源: Ann Intern Med. 2026年179卷1期81-94页
Seasonal influenza is a contagious viral respiratory illness that causes yearly epidemics.
18. Efficacy of Individual-Level Interventions to Mitigate the Risk for Burnout Among Health Care Professionals : A Systematic Review and Meta-analysis of Randomized Controlled Trials.
作者: George Collett.;Jaya Gupta.;Abubaker Eltayeb.;Ania Korszun.;Linda Sharples.;Kenneth Rice.;Ajay K Gupta.
来源: Ann Intern Med. 2026年179卷1期51-66页
There is limited evidence of the strategies to mitigate burnout among all health care professionals (HCPs).
19. Implementation of Social Needs Screening and Intervention in Primary Care : A Systematic Review of Program-Level Determinants.
作者: Eva Chang.;Iridian Guzman.;Nicole Glowacki.;Rasha Khatib.
来源: Ann Intern Med. 2026年179卷1期95-106页
Health care systems are investing significant resources in social needs screening and intervention programs.
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