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1. Efficacy of Individual-Level Interventions to Mitigate the Risk for Burnout Among Health Care Professionals : A Systematic Review and Meta-analysis of Randomized Controlled Trials.
作者: George Collett.;Jaya Gupta.;Abubaker Eltayeb.;Ania Korszun.;Linda Sharples.;Kenneth Rice.;Ajay K Gupta.
来源: Ann Intern Med. 2026年179卷1期51-66页
There is limited evidence of the strategies to mitigate burnout among all health care professionals (HCPs).
2. Proteinuria or Albuminuria as Markers of Kidney and Cardiovascular Disease Risk : An Individual Patient-Level Meta-analysis.
作者: Hiddo J L Heerspink.;Morgan E Grams.;Yingying Sang.;Shoshana H Ballew.;Josef Coresh.;Aditya Surapaneni.;Natalia Alencar de Pinho.;Nigel J Brunskill.;Alexander R Chang.;Elizabeth Ciemins.;Laura M Dember.;Keiko Kabasawa.;Lindsey Kornowske.;Adeera Levin.;Rupert Major.;Patrick B Mark.;Eric McArthur.;James Medcalf.;Marie Metzger.;Girish N Nadkarni.;David M J Naimark.;Cassianne Robinson-Cohen.;Keiichi Sumida.;Robin W M Vernooij.;Ron T Gansevoort.;Bengt Fellström.;Steven Chadban.; .
来源: Ann Intern Med. 2026年179卷1期32-41页
Urinary albumin-creatinine ratio (UACR) and urinary protein-creatinine ratio (UPCR) are both used in clinical practice to diagnose and monitor chronic kidney disease (CKD). Which measure exhibits stronger associations with clinical outcomes and whether this varies by patient characteristics are unknown.
3. The Effect of Weight Loss Before In Vitro Fertilization on Reproductive Outcomes in Women With Obesity : A Systematic Review and Meta-analysis.
作者: Moscho Michalopoulou.;Susan Ann Jebb.;Alice Hobson.;Shen Chuen Khaw.;Richard Stevens.;Pedro Melo.;Stella Jane Pierce Haffner.;Kathryn Sheridan Clay.;Sarah Mounsey.;Ingrid Granne.;Lee Lim.;Tim Child.;Nerys Marie Astbury.
来源: Ann Intern Med. 2025年178卷9期1298-1313页
It is unclear whether weight loss before in vitro fertilization (IVF) improves reproductive outcomes in women with obesity.
4. Moderate- to Long-Term Effect of Dietary Interventions for Depression and Anxiety : A Systematic Review and Meta-analysis.
作者: Eman Abukmail.;Neeraj Koloth Pradeep.;Samantha Ahmed.;Loai Albarqouni.
来源: Ann Intern Med. 2025年178卷7期987-999页
Dietary interventions are a potential alternative treatment of depression and anxiety.
5. Effectiveness of Synchronous Postdischarge Contacts on Health Care Use and Patient Satisfaction : A Systematic Review and Meta-analysis.
作者: Joel C Boggan.;Spoorthi Sankineni.;Paul A Dennis.;Dazhe Chen.;Tina Wong Sledge.;David Halpern.;Sharron Rushton.;John W Williams.;Tatyana Der.;Amir Alishahi Tabriz.;Adelaide M Gordon.;Morgan Jacobs.;Nathan A Boucher.;Maria Colandrea.;Anastasia-Stefania Alexopoulos.;Joanne Roman Jones.;Nina Leflore-Lloyd.;Sarah Cantrell.;Karen M Goldstein.;Jennifer M Gierisch.
来源: Ann Intern Med. 2025年178卷2期229-240页
Postdischarge contacts (PDCs) after hospitalization are common practice, but their effectiveness in reducing use of acute care after discharge remains unclear.
6. Anticoagulation Among Patients Hospitalized for COVID-19 : A Systematic Review and Prospective Meta-analysis.
作者: .;Claire L Vale.;Peter J Godolphin.;David J Fisher.;Julian P T Higgins.;Alexandra McAleenan.;Francesca Spiga.;Tobias Tritschler.;Pedro Gabriel Melo de Barros E Silva.;David D Berg.;Jeffrey S Berger.;Lindsay R Berry.;Behnood Bikdeli.;Marc Blondon.;Erin A Bohula.;Marco Cattaneo.;Riccardo Colombo.;Valeria Coluccio.;Maria T DeSancho.;Michael E Farkouh.;Valentin Fuster.;Massimo Girardis.;Judith S Hochman.;Thomas P Jensen.;Vivekanand Jha.;Peter Jüni.;Ajay J Kirtane.;Patrick Lawler.;Grégoire Le Gal.;Ramon Lecumberri.;Steven R Lentz.;Renato D Lopes.;Elizabeth Lorenzi.;Marco Marietta.;Carlos Henrique Miranda.;Nuccia Morici.;Susan C Morpeth.;David A Morrow.;Zoe K McQuilten.;Nuria Muñoz-Rivas.;Matthew D Neal.;Suman Pant.;Sahil A Parikh.;Usha Perepu.;Parham Sadeghipour.;Sanjum Sethi.;Michelle Sholzberg.;Alex C Spyropoulos.;Gregg W Stone.;Azita Hajhossein Talasaz.;Steven Tong.;James Totterdell.;Balasubramanian Venkatesh.;Maddalena Alessandra Wu.;Ryan Zarychanski.;Stephane Zuily.;Julie Viry.;Jamie Rylance.;Neill K J Adhikari.;Janet V Diaz.;John C Marshall.;Jonathan A C Sterne.;Srinivas Murthy.
来源: Ann Intern Med. 2025年178卷1期59-69页
Reported results of clinical trials assessing higher-dose anticoagulation in patients hospitalized for COVID-19 have been inconsistent.
7. Artificial Intelligence-Assisted Colonoscopy for Polyp Detection : A Systematic Review and Meta-analysis.
作者: Saeed Soleymanjahi.;Jack Huebner.;Lina Elmansy.;Niroop Rajashekar.;Nando Lüdtke.;Rumzah Paracha.;Rachel Thompson.;Alyssa A Grimshaw.;Farid Foroutan.;Shahnaz Sultan.;Dennis L Shung.
来源: Ann Intern Med. 2024年177卷12期1652-1663页
Randomized clinical trials (RCTs) of computer-aided detection (CADe) system-enhanced colonoscopy compared with conventional colonoscopy suggest increased adenoma detection rate (ADR) and decreased adenoma miss rate (AMR), but the effect on detection of advanced colorectal neoplasia (ACN) is unclear.
8. Update Alert 2: Nonpharmacologic and Pharmacologic Treatments of Adult Patients With Major Depressive Disorder: A Systematic Review and Network Meta-Analysis for a Clinical Guideline by the American College of Physicians.
作者: Andreea Iulia Dobrescu.;Emma Persad.;Irma Klerings.;Gerald Gartlehner.
来源: Ann Intern Med. 2024年177卷8期e2400428页 9. Angiotensin-Converting Enzyme Inhibitors or Angiotensin-Receptor Blockers for Advanced Chronic Kidney Disease : A Systematic Review and Retrospective Individual Participant-Level Meta-analysis of Clinical Trials.
作者: Elaine Ku.;Lesley A Inker.;Hocine Tighiouart.;Charles E McCulloch.;Ogechi M Adingwupu.;Tom Greene.;Raymond O Estacio.;Mark Woodward.;Dick de Zeeuw.;Julia B Lewis.;Thierry Hannedouche.;Tazeen H Jafar.;Enyu Imai.;Giuseppe Remuzzi.;Hiddo J L Heerspink.;Fan Fan Hou.;Robert D Toto.;Philip K Li.;Mark J Sarnak.
来源: Ann Intern Med. 2024年177卷7期953-963页
In patients with advanced chronic kidney disease (CKD), the effects of initiating treatment with an angiotensin-converting enzyme inhibitor (ACEi) or angiotensin-receptor blocker (ARB) on the risk for kidney failure with replacement therapy (KFRT) and death remain unclear.
10. Associations of Testosterone and Related Hormones With All-Cause and Cardiovascular Mortality and Incident Cardiovascular Disease in Men : Individual Participant Data Meta-analyses.
作者: Bu B Yeap.;Ross J Marriott.;Girish Dwivedi.;Robert J Adams.;Leen Antonio.;Christie M Ballantyne.;Douglas C Bauer.;Shalender Bhasin.;Mary L Biggs.;Peggy M Cawthon.;David J Couper.;Adrian S Dobs.;Leon Flicker.;David J Handelsman.;Graeme J Hankey.;Anke Hannemann.;Robin Haring.;Benjumin Hsu.;Sean A Martin.;Alvin M Matsumoto.;Dan Mellström.;Claes Ohlsson.;Terence W O'Neill.;Eric S Orwoll.;Matteo Quartagno.;Molly M Shores.;Antje Steveling.;Åsa Tivesten.;Thomas G Travison.;Dirk Vanderschueren.;Gary A Wittert.;Frederick C W Wu.;Kevin Murray.
来源: Ann Intern Med. 2024年177卷6期768-781页
Whether circulating sex hormones modulate mortality and cardiovascular disease (CVD) risk in aging men is controversial.
11. Update Alert: Effectiveness and Safety of Treatments to Prevent Fractures in People With Low Bone Mass or Primary Osteoporosis: A Living Systematic Review and Network Meta-analysis for the American College of Physicians.12. Newer Pharmacologic Treatments in Adults With Type 2 Diabetes: A Systematic Review and Network Meta-analysis for the American College of Physicians.
作者: Tyler Drake.;Adrienne Landsteiner.;Lisa Langsetmo.;Roderick MacDonald.;Maylen Anthony.;Caleb Kalinowski.;Kristen Ullman.;Charles J Billington.;Anjum Kaka.;Shahnaz Sultan.;Timothy J Wilt.
来源: Ann Intern Med. 2024年177卷5期618-632页
Newer diabetes medications may have beneficial effects on mortality, cardiovascular outcomes, and renal outcomes.
13. Long-Term Effect of Salt Substitution for Cardiovascular Outcomes : A Systematic Review and Meta-analysis.
作者: Hannah Greenwood.;Katelyn Barnes.;Justin Clark.;Lauren Ball.;Loai Albarqouni.
来源: Ann Intern Med. 2024年177卷5期643-655页
Salt substitution is a simple yet increasingly promising strategy to improve cardiovascular outcomes.
14. Development and Validation of a Protein Risk Score for Mortality in Heart Failure : A Community Cohort Study.
作者: Kayode O Kuku.;Joseph J Shearer.;Maryam Hashemian.;Rebecca Oyetoro.;Hoyoung Park.;Brittany Dulek.;Suzette J Bielinski.;Nicholas B Larson.;Peter Ganz.;Daniel Levy.;Bruce M Psaty.;Jungnam Joo.;Véronique L Roger.
来源: Ann Intern Med. 2024年177卷1期39-49页
Heart failure (HF) is a complex clinical syndrome with high mortality. Current risk stratification approaches lack precision. High-throughput proteomics could improve risk prediction. Its use in clinical practice to guide the management of patients with HF depends on validation and evidence of clinical benefit.
15. Major Update: Masks for Prevention of SARS-CoV-2 in Health Care and Community Settings-Final Update of a Living, Rapid Review.
Optimal use of masks for preventing COVID-19 is unclear.
16. Nonpharmacologic and Pharmacologic Treatments of Adult Patients With Major Depressive Disorder: A Systematic Review and Network Meta-analysis for a Clinical Guideline by the American College of Physicians.
作者: Gerald Gartlehner.;Andreea Dobrescu.;Andrea Chapman.;Ana Toromanova.;Robert Emprechtinger.;Emma Persad.;Lisa Affengruber.;Christoph Pieh.;Irma Klerings.;Gernot Wagner.
来源: Ann Intern Med. 2023年176卷2期196-211页
Primary care patients and clinicians may prefer alternative options to second-generation antidepressants for major depressive disorder (MDD).
17. Effectiveness and Safety of Treatments to Prevent Fractures in People With Low Bone Mass or Primary Osteoporosis: A Living Systematic Review and Network Meta-analysis for the American College of Physicians.
作者: Chelsea Ayers.;Devan Kansagara.;Brittany Lazur.;Rongwei Fu.;Amy Kwon.;Curtis Harrod.
来源: Ann Intern Med. 2023年176卷2期182-195页
The prevalence of osteoporosis is increasing in the United States.
18. The Impact of the COVID-19 Pandemic and Associated Control Measures on the Mental Health of the General Population : A Systematic Review and Dose-Response Meta-analysis.
作者: Georgia Salanti.;Natalie Peter.;Thomy Tonia.;Alexander Holloway.;Ian R White.;Leila Darwish.;Nicola Low.;Matthias Egger.;Andreas D Haas.;Seena Fazel.;Ronald C Kessler.;Helen Herrman.;Christian Kieling.;Dominique J F De Quervain.;Simone N Vigod.;Vikram Patel.;Tianjing Li.;Pim Cuijpers.;Andrea Cipriani.;Toshi A Furukawa.;Stefan Leucht.; .;Abdulkadir Usman Sambo.;Akira Onishi.;Akira Sato.;Alessandro Rodolico.;Ana Cristina de Oliveira Solis.;Anastasia Antoniou.;Angelika Kapfhammer.;Anna Ceraso.;Aoife O'Mahony.;Aurélie M Lasserre.;Aziz Mert Ipekci.;Carmen Concerto.;Caroline Zangani.;Chinonso Igwesi-Chidobe.;Christina Diehm.;Dicle Dilay Demir.;Dongfang Wang.;Edoardo Giuseppe Ostinelli.;Ethan Sahker.;Gabriel Henrique Beraldi.;Gamze Erzin.;Harrison Nelson.;Helio Elkis.;Hissei Imai.;Hui Wu.;Ilias Kamitsis.;Ioannis Filis.;Ioannis Michopoulos.;Irene Bighelli.;James S W Hong.;Javier Ballesteros.;Katharine A Smith.;Kazufumi Yoshida.;Kenji Omae.;Marialena Trivella.;Masafumi Tada.;Matthias A Reinhard.;Michael J Ostacher.;Monika Müller.;Nathalia Gonzalez Jaramillo.;Panagiotis P Ferentinos.;Rie Toyomoto.;Samuele Cortese.;Sanae Kishimoto.;Sergio A Covarrubias-Castillo.;Spyridon Siafis.;Trevor Thompson.;Vasilios Karageorgiou.;Virginia Chiocchia.;Yikang Zhu.;Yukiko Honda.; .
来源: Ann Intern Med. 2022年175卷11期1560-1571页
To what extent the COVID-19 pandemic and its containment measures influenced mental health in the general population is still unclear.
20. Effectiveness and Harms of Contraceptive Counseling and Provision Interventions for Women : A Systematic Review and Meta-analysis.
作者: Heidi D Nelson.;Amy Cantor.;Rebecca M Jungbauer.;Karen B Eden.;Blair Darney.;Katherine Ahrens.;Amanda Burgess.;Chandler Atchison.;Rose Goueth.;Rongwei Fu.
来源: Ann Intern Med. 2022年175卷7期980-993页
The effectiveness and harms of contraceptive counseling and provision interventions are unclear.
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