161. In symptomatic AF, nurse-led pre-ablation lifestyle treatment reduced repeat ablations or cardioversions at 1 y.
GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text].
166. In provoked VTE with ≥1 enduring risk factor, extending anticoagulation with apixaban reduced symptomatic recurrent VTE at 12 mo.
GIM/FP/GP: [Formula: see text] Hematology: [Formula: see text].
168. In older adults, RSV prefusion F vaccine reduced hospitalization for RSV-related respiratory tract disease vs. no vaccine.
GIM/FP/GP: [Formula: see text] Geriatrics: [Formula: see text] Infectious Disease: [Formula: see text] Pulmonology: [Formula: see text].
169. In hypercholesterolemia, adding inclisiran to individually optimized lipid-lowering therapy improved LDL-C levels at 90 d.
GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text].
171. In older adults with impaired physical performance after MI, multidomain rehabilitation reduced CV death or CV hospitalization at 1 y.
GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text] Geriatrics: [Formula: see text].
173. Effectiveness and Safety of Statins in Type 2 Diabetes According to Baseline Cardiovascular Risk : A Target Trial Emulation Study.
作者: Vincent Ka Chun Yan.;Joseph Edgar Blais.;John-Michael Gamble.;Esther Wai Yin Chan.;Ian Chi Kei Wong.;Eric Yuk Fai Wan.
来源: Ann Intern Med. 2026年179卷2期157-167页
Whether statins benefit patients with type 2 diabetes mellitus (T2DM) with low predicted 10-year cardiovascular risk is uncertain.
174. 2025 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline for the Primary Care Management of Chronic Kidney Disease.
作者: Amy R Schwartz.;Jonathan Sosnov.;Jonathan Brown.;Cynthia Delgado.;Linda Fried.;Manjula Kurella Tamura.;John W Morrison.;Sankar D Navaneethan.;Paul M Palevsky.;Diane Rybacki.;James Sall.;Sunil Verma.;Maura Watson.;Jesse Wickham.;Mai Nguyen.
来源: Ann Intern Med. 2026年179卷3期411-424页
Management of chronic kidney disease (CKD) has been rapidly evolving, now involving many interventions that can be managed in the primary care setting. In April 2025, leadership within the U.S. Department of Veterans Affairs (VA) and U.S. Department of Defense (DoD) approved a joint clinical practice guideline (CPG) for the primary care management of CKD. This synopsis reviews the 2025 recommendations related to diagnosis, assessment, and management of CKD.
177. Once-Weekly Oral Islatravir Plus Lenacapavir Versus Daily Oral Bictegravir, Emtricitabine, and Tenofovir Alafenamide in Persons With HIV-1 : A Phase 2 Randomized Study.
作者: Amy E Colson.;Gordon E Crofoot.;Peter J Ruane.;Moti N Ramgopal.;Alexandra W Dretler.;Ronald G Nahass.;Gary I Sinclair.;Mezgebe Berhe.;Afsoon Roberts.;Shauna Applin.;Cynthia Brinson.;Dushyantha Jayaweera.;Kimberly A Workowski.;Fadi Shihadeh.;Shan-Yu Liu.;Stephanie Klopfer.;Cyril Llamoso.;Sharline Madera.;Hadas Dvory-Sobol.;Martin S Rhee.;Elizabeth G Rhee.;Jared M Baeten.;Joseph J Eron.
来源: Ann Intern Med. 2026年179卷2期168-176页
Once-weekly oral islatravir plus lenacapavir (ISL+LEN) has the potential to address adherence challenges with daily HIV-1 treatment.
|