当前位置: 首页 >> 检索结果
141. Identification of a dihydroartemisinin-related prognostic signature and its contribution to cancer associated fibroblast of the tumor microenvironment of pancreatic cancer.
作者: Jinglin Lai.;Tongning Zhong.;Citing Zhang.;Chongzhou Fang.;Defeng Lei.;Yong Xie.;Xu Liu.;Zhengquan Lai.;Zilong Yan.;Weipeng Ai.;Jianhua Qu.;Biao Zheng.
来源: BMC Gastroenterol. 2025年25卷1期656页
Pancreatic ductal adenocarcinoma (PDAC) is characterized by high metastatic potential and a stroma-rich tumor microenvironment (TME). Dihydroartemisinin (DHA) has shown antitumor potential in various cancers, but its therapeutic effects on the TME of PDAC are not yet understood.
142. Chemerin as a biomarker of inflammatory bowel diseases: a meta-analysis.
作者: Zhi Tian.;Qun Xiang.;Meichun Long.;Jiangtao Liao.;Fang Wang.;Xuefeng Li.
来源: BMC Gastroenterol. 2025年25卷1期662页
Chemerin, an adipokine involved in immune regulation and inflammation, has been implicated in the pathogenesis of inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC). However, existing studies have reported inconsistent findings regarding its diagnostic value. This meta-analysis aimed to clarify the association between blood chemerin levels and IBD.
143. Comparative analysis of tenofovir alafenamide and entecavir on renal function and serum lipids in liver transplant recipients: a controlled retrospective cohort study.
作者: Hüseyin Döngelli.;Nilay Danış.;Tarkan Ünek.;Tufan Egeli.;Cihan Ağalar.;Mücahit Özbilgin.;Hülya Ellidokuz.;Mesut Akarsu.
来源: BMC Gastroenterol. 2025年25卷1期645页
Antiviral treatments can impact serum lipids as well as kidney function. We conducted a retrospective observational study with a 48-month follow-up period, involving liver transplant recipients receiving either entecavir or tenofovir alafenamide, to assess the effects of these antiviral medications on serum lipids and renal function.
144. The impact of fecal microbiota transplantation on refractory ulcerative colitis: A systematic review and Meta-Analysis of randomised controlled trials.
作者: Chidi Arthur Igbo.;Chimezirim Ezeano.;Olanrewaju Adeniran.;Maher Taha.;Albert Alexis Annan.;Valentine C Nriagu.;Sarpong Boateng.;Madu Chimezie Williams.;Chike Onyali.
来源: BMC Gastroenterol. 2025年25卷1期654页
Refractory ulcerative colitis (UC), characterized by persistent disease activity despite optimized medical therapy, poses a significant therapeutic challenge. Fecal microbiota transplantation (FMT) has shown promise in inducing remission in active ulcerative colitis (UC) by restoring gut microbial balance; however, its efficacy in refractory cases remains unclear. This systematic review and meta-analysis aimed to evaluate the effectiveness and safety of FMT in achieving clinical and endoscopic remission in patients with refractory UC, based on evidence from randomized controlled trials (RCTs).
145. Effect of single-day versus multi-day low-residue diet on colonoscopy bowel preparation: a systematic review and meta -analysis.
To compare the effects of single-day and multi-day low-residue diets on bowel preparation quality and patient tolerance of colonoscopy.
146. Lactate-to-albumin ratio as an independent predictor of mortality in critically ill patients with gastrointestinal bleeding: a retrospective cohort study.
作者: Xingyi Yang.;Shasha Ying.;Xiangshu Yuan.;Jiaqian Ying.;Ji Yang.;Lihong Lv.
来源: BMC Gastroenterol. 2025年25卷1期653页
The lactate-to-albumin ratio (LAR) is an established prognostic marker in various critical illnesses; However, its association with gastrointestinal bleeding (GIB) in patients has not been thoroughly investigated. This study evaluates the prognostic role of LAR in critically ill patients with GIB.
147. Impact of periampullary diverticulum and relevant cannulation techniques on the outcomes of endoscopic retrograde cholangiopancreatography: a retrospective study.
作者: Erfan Arabpour.;Amir Sadeghi.;Ava Rashtchian.;Reyhaneh Rastegar.;Mohammad Abdehagh.;Mohammad Reza Zali.
来源: BMC Gastroenterol. 2025年25卷1期665页
Periampullary diverticulum (PAD) is an incidental finding during endoscopic retrograde cholangiopancreatography (ERCP), occurring more frequently in elderly patients. The influence of PAD on the ERCP procedure has been a subject of debate. The aim of this study was to investigate the impact of PAD on ERCP outcomes.
148. Associations between socio-demographic factors, social functioning, and sleep quality among GERD patients in Syria: a cross-sectional study.
作者: Jamal Ataya.;Joudy Sharkatli.;Mohamad Yousef Almawaz.;Tarek Wahbeh.;Alaa Alsarhan.;Saeed Kadri.;Yara Mangal.;Rahaf Alawad.;Ali Hmidoush.;Sara Alashkar.;Mouayad Zarzar.
来源: BMC Gastroenterol. 2025年25卷1期647页
Gastroesophageal reflux disease (GERD) is a prevalent chronic digestive disorder that significantly affects patients’ quality of life. The aim of this study was to assess the relationships among sociodemographic characteristics, social functioning, sleep quality, and symptom severity in patients with GERD.
149. Elevated CircYthdc2 expression is correlated with aggressive features and poor progression-free survival in hepatocellular carcinoma.
Liver hepatocellular carcinoma (LIHC) is a major contributor to cancer-related mortality. While early detection is crucial for improving outcomes, current diagnostic methods lack optimal sensitivity and specificity. Circular RNAs (circRNAs) have emerged as promising biomarkers due to their stability and tissue-specific expression.
150. Low-molecular-weight heparin alleviates L-arginine-induced acute pancreatitis by modulating lipid metabolism and inflammatory responses in a rat model.
作者: Jianmei Zeng.;Kejin Li.;Limao Xu.;Chengfeng Wu.;Fei Wang.;Juan Huang.
来源: BMC Gastroenterol. 2025年25卷1期644页
This study investigates the therapeutic potential of low-molecular-weight heparin (LMWH) in acute pancreatitis (AP), focusing on its effects on lipid metabolism, inflammatory responses, and pancreatic tissue integrity. The study also explores the involvement of the PI3K/Akt pathway in mediating LMWH’s protective effects.
151. Impact of withdrawal time on the adenoma detection rate in elderly patients during unsedated colonoscopy: a retrospective multicenter study.
作者: Fu-Qiang Liu.;Ying-Hao He.;Han Yan.;Jin-Wen Liao.;Wen-Juan Ding.;Yu-Ting Huang.;Zhi-Qiang Du.;Xiang-Rong Zhou.;Zheng Jiang.
来源: BMC Gastroenterol. 2025年25卷1期660页
Colonoscopy withdrawal time is recognized as a key factor influencing the adenoma detection rate (ADR). Current clinical guidelines recommend a minimum colonoscopy withdrawal time of 6 min. However, the optimal withdrawal time for unsedated colonoscopy in elderly patients and its impact on ADR remain uncertain.
152. Resolvin D1 values in patients with alcohol-associated liver disease.
Resolvin D1 (RvD1), a specialized pro-resolving lipid mediator, has been associated with liver injury in experimental models of alcohol-associated liver disease (ALD). This study aimed to evaluate the relationship between serum RvD1 levels and clinical phenotypes of ALD.
153. Association of urinary metal exposure with H. pylori seropositivity and mortality in the U.S. Population: NHANES 1999-2000 analysis.
The relationship between urinary heavy metal concentrations and overall mortality remains understudied, particularly among individuals with Helicobacter pylori (H. pylori) infection. This study aimed to explore the associations between urinary concentrations of specific metals and H. pylori seropositivity, as well as to evaluate their respective associations with all-cause mortality in both H. pylori-infected and non-infected subpopulations.
154. Risk factor analysis and nomogram development for survival prediction in obese patients with severe acute pancreatitis: a retrospective study.
作者: Qingcheng Zhu.;Xueqin Shan.;Dingyu Tan.;Mingfeng Lu.;Yan Xu.
来源: BMC Gastroenterol. 2025年25卷1期651页
Currently, there is a lack of nomograms specifically designed to predict mortality risk in obese patients with severe acute pancreatitis (SAP). The aim of our study is to develop a predictive model tailored to this population, enabling more accurate anticipation of overall survival.
155. Association between the ApoB/ApoA1 ratio and both the severity and mortality of metabolic dysfunction-associated fatty liver disease.
作者: Chao Fu.;Yan Gong.;Xiangyang Gao.;Yuxin Li.;Guanyun Wang.;Bingqing Han.;Shanshan Liu.;Hao Zhang.;Dengxin He.;Fei Wang.;Qiang Zeng.
来源: BMC Gastroenterol. 2025年25卷1期650页 156. Human epidermal growth factor receptor 2 expression and socio-demographic, clinical, and histopathological characteristics in gastric carcinoma at St Francis Hospital Nsambya, Uganda.
作者: Steven Wanda.;Gorretti Nassali.;Brian Bbosa.;Francis Basimbe.;Joviah Akulu.;Davis Nsamba.;Praise Nimusiima.;Joshua Muhumuza.;Emmanuel Othieno.;Maxwel Dancan Okuku.
来源: BMC Gastroenterol. 2025年25卷1期655页
Gastric carcinoma is a significant global health burden with diverse clinicopathological features and molecular alterations influencing prognosis and treatment. Human epidermal growth factor receptor 2 (HER2) overexpression is a critical biomarker in gastric carcinoma, guiding targeted therapeutic interventions. This study aimed to assess HER2 expression and its association with clinicopathological characteristics of gastric carcinoma.
157. Differences and clinical significance of liver - kidney function parameters, inflammatory markers and peripheral blood T lymphocyte subsets in patients with HBV - related acute - on - chronic liver failure.
The study aimed to explore the changes and clinical significance of hepatic-renal functions, inflammatory markers, and peripheral blood T lymphocyte subsets in patients with hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF).
158. Portal vein thrombosis and associated factors among patients admitted to Tibebe Ghion hospital, Bahir Dar, Ethiopia: a cross-sectional study, 2021-2024.
作者: Getie Baylie Alem.;Dessalegne Nigatu Achenef.;Tsion Adebabay Kassie.;Gebeyaw Addis Bezie.
来源: BMC Gastroenterol. 2025年25卷1期646页
Portal vein thrombosis (PVT) is a Liver vascular disease characterized by the development of a blood clot inside the portal vein's main branches or trunk. There are limited studies on PVT and associated factors in Africa, with no studies from Ethiopia. Therefore, this study was conducted to assess the prevalence of portal vein thrombosis and associated factors among patients at the TGSH medical ward in Bahir Dar, Ethiopia, from January 1, 2021, to December 31, 2024.
159. Association between the TyG index and MAFLD and its subtypes: a population-based cross-sectional study.
作者: Cui'e Liu.;Chaochen Li.;Jia Fu.;Long Bai.;Man Wang.;Pei Song.;Meng Zheng.
来源: BMC Gastroenterol. 2025年25卷1期652页
The association between triglyceride-glucose (TyG) index and metabolic dysfunction-associated fatty liver disease (MAFLD) and its subtypes in the U.S. population remains unclear. This study aims to investigate this relationship.
160. Cancer disparities in lean vs. non-lean MASH: insight from a national inpatient sample.
作者: Chukwunonso Ezeani.;Chidiebele Omaliko.;Petr Protiva.;Yazan A Al-Ajlouni.;Gyanprakash Ketwaroo.;Basile Njei.
来源: BMC Gastroenterol. 2025年25卷1期659页
To investigate cancer disparities between lean (BMI < 25 kg/m²; < 23 kg/m² for Asians) and non-lean metabolic dysfunction-associated steatohepatitis (MASH) by analyzing the prevalence of the 18 most common cancers in a large U.S.
|