121. Pulmonary Fungal Infections in the Immunocompetent Host.
Pulmonary fungal infections, which have traditionally been associated with patients who are immunocompromised, are now increasingly recognized among immunocompetent individuals. This trend is attributable to multiple factors including altered environmental conditions linked to climate change, postviral syndromes, and advances in ICU practices. Immunocompetent hosts typically generate effective responses to pulmonary fungal infection; however, severe disease may develop in the presence of abnormal lung structure or function, transient immune dysfunction, or antigenic hypersensitivity.
122. Shaping the Future of Respiratory Care: A Look Into the Next Decade and Strategic Recommendations by European Forum for Research and Education in Allergy and Airways Diseases.
作者: Xander Bertels.;G K Scadding.;V Backer.;S Lau.;W J Fokkens.;P J Barnes.;M Bernal Sprekelsen.;L Bjermer.;M Blaiss.;E Borzova.;M C Brüggen.;G G Brusselle.;L Cardell.;D M Conti.;M Cornet.;E De Corso.;B De Groeve.;R Djukanovic.;A T Fox.;M Gaga.;P Gevaert.;P Gibson.;C Gray.;J Han.;L Heaney.;E Heffler.;H J Hoffmann.;C Hopkins.;D Jackson.;O Jauhola.;M Jesenak.;P Johansen.;E Khaleva.;B Landis.;S Lee.;V Lund.;M Mäkelä.;M McDonald.;E Melén.;J Mullol.;A Nieto-García.;I Pavord.;A Peters.;D Price.;S Quirce.;D Ryan.;P Sahlstrand-Johnson.;S Scheire.;P Schmid-Grendelmeier.;S Schneider.;B Senior.;C M E Shire.;P Smith.;Z Szepfalusi.;M T A Teeling.;M E Wechsler.;P Houssiau.;K F Rabe.;P W Hellings.;J L Castro.
来源: Chest. 2026年
Chronic respiratory diseases (CRDs) remain one of the leading causes of preventable morbidity and disability worldwide, affecting up to one-third of the total Western population in 2025. Recognizing the substantial burden of inflammatory airway diseases such as asthma, COPD, chronic rhinosinusitis, and respiratory allergy, the European Forum for Research and Education in Allergy and Airway diseases (EUFOREA) organized the symposium "Shaping the Future of Respiratory Care" in April 2025 in Brussels, Belgium, at the occasion of the 10-year jubilee. Featuring keynote speakers from the World Health Organization and EUFOREA, this initiative had the following aims: (1) promoting dialogue on translating innovations into daily clinical practice; (2) encouraging collaboration between the different stakeholders in the respiratory field; and (3) defining strategic priorities to transform respiratory care and arrest the CRD epidemic over the next decade. The symposium highlighted the importance of moving toward predictive, preventive, and patient-centered medicine, while supporting value-based health care systems to improve long-term patient outcomes. This report summarizes the main insights and strategic directions discussed at the meeting.
123. Efficacy of Antiinflammatory Therapies for Adults With Non-Cystic Fibrosis Bronchiectasis: A Systematic Review and Network Meta-Analysis.
作者: Shota Yamamoto.;Takayuki Niitsu.;Kiyoharu Fukushima.;Ayako Shiozawa.;Ryosuke Imai.;Kazuki Hashimoto.;Kenneth N Olivier.;Timothy R Aksamit.;Kozo Morimoto.
来源: Chest. 2026年
Non-cystic fibrosis bronchiectasis is characterized by chronic respiratory symptoms and radiologic airway dilatation. Sustained neutrophilic inflammation is a key driver, prompting interest in antiinflammatory pharmacotherapy as a new treatment paradigm; however, comparisons among antiinflammatory agents are lacking.
124. Associations Between Prior Lung Diseases and Risk of Lung Cancer in Populations With No Smoking History: A Systematic Review and Meta-Analysis.
作者: Nishwant Swami.;Ji Hyun Hong.;Sooyeon Kho.;Hae Min Kang.;Laura Chun-Chia Lin.;Shy Chwen Ni.;Narjust Florez.;Qing Lan.;Nat Rothman.;Edward Christopher Dee.;Scarlett Lin Gomez.;Iona Cheng.
来源: Chest. 2026年
Individuals who do not smoke account for a growing proportion of lung cancer (LC) incidence, but the impact of prior lung diseases on lung cancer risk in this population remains unclear.
125. Reliability of Clinic-Obtained vs Self-Obtained Respiratory Samples From the Self-Sample Accuracy and Benefit Implementation Trial (S2wAB-IT).
作者: Jordana E Hoppe.;Andrew Paisley.;Tim Vigers.;Kathryn Moffett.;Veronica Indihar.;Elliott Dasenbrook.;Joel E Mortensen.;Marianne S Muhlebach.;Christopher Siracusa.
来源: Chest. 2026年
Routine surveillance cultures are critical in the care of patients with cystic fibrosis (CF) and are used in clinical decision-making. Due to the improved health of people with CF (pwCF) and the increased use of telehealth for clinical care, there is a strong interest in providing remote care, including remote respiratory specimen collection.
126. Formation and Growth of a Bronchiectasis and Pulmonary Nontuberculous Mycobacteria Multidisciplinary Program Using a Patient-Centered and Integrated Care Model Improves Outcomes.
作者: B Shoshana Zha.;Martin Ieong.;Isabella Cheng.;Seth Bokser.;Cynthia Fenton.;Anoop Muniyappa.;Jeffrey Tarnow.;Vicki Jue.;Catherine DeVoe.;Mary Ellen Kleinhenz.;Neeta Thakur.
来源: Chest. 2026年
Bronchiectasis and pulmonary nontuberculous mycobacteria (NTM) infections are chronic diseases that can cause debilitating respiratory symptoms, exacerbations, and even lead to respiratory failure. Clinical care has historically been provided by individual specialists, but multidisciplinary care teams have recently emerged to improve evaluation of underlying etiology and interventions that disrupt the trajectory of disease progression.
127. Hospital Variation in Invasive Mediastinal Staging for Patients With Stage I Lung Cancer Treated With Radiation.
作者: Bilal Odeh.;Alexander Pohlman.;Ayham Odeh.;Amit Goyal.;Matthew M Harkenrider.;Zaid M Abdelsattar.
来源: Chest. 2026年
The use of invasive mediastinal staging (IMS) before radiation therapy in patients with early stage lung cancer is variable. The reasons for this variation and whether it affects outcomes is unknown. In this context, we conducted a patient- and hospital-level analysis to better understand the impact of this variation.
128. Evaluating Text Messaging Approaches to Promote Enrollment in Smoking Cessation Treatment Among Latino Adults: A Pragmatic Randomized Clinical Trial.
作者: Francisco Cartujano-Barrera.;Delwyn Catley.;Arlette Chávez-Iñiguez.;Andrew T Fox.;Hongmei Yang.;Katherine K Rieth.;Andrea Holland.;Kimber Richter.;Scott E Sherman.;Gary Slagle.;Scott Werntz.;Ana Paula Cupertino.
来源: Chest. 2026年
Little is known about the use of text messages to promote enrollment in smoking cessation treatment.
129. Pseudomonas aeruginosa in Patients With Nosocomial Respiratory Infections: A Secondary Analysis of the European Network for ICU-Related Respiratory Infections.
作者: Cristian C Serrano-Mayorga.;Juan Olivella-Gomez.;Natalia Sanabria-Herrera.;Saad Nseir.;Antoni Torres.;Ignacio Martin-Loeches.;Luis F Reyes.; .
来源: Chest. 2026年
Nosocomial respiratory infections (NRIs) are the most common complication among patients in the ICU, with Pseudomonas aeruginosa frequently identified. However, the global prevalence of P aeruginosa and associated risk factors remain unclear.
130. Unraveling the Connection Between Respiratory Distress and Hypertension in an 18-Month-Old Girl.
An 18-month-old girl presented to the emergency department with a 1-month history of fever, cough, and difficulty breathing. The cough was progressive over 1 month and productive in nature. Before this admission, she had been hospitalized for 21 days at another facility, where she required intubation and ventilation for 8 days and received IV antibiotics and nebulization for Pseudomonas aeruginosa pneumonia. The child was the firstborn of a nonconsanguineous marriage, with an unremarkable antenatal and natal history. Her developmental milestones were appropriate for her age, and she had completed age-appropriate immunizations without adverse reactions. Mother had history of 2 spontaneous abortions, both in the first trimester.
136. Diagnostic Yield and Synergistic Impact of Needle Aspiration and Forceps Biopsy With Electromagnetic Navigation Bronchoscopy for Peripheral Pulmonary Lesions: A Randomized Controlled Trial. |