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121. Preventing Hospital Readmission for Patients With Comorbid Substance Use Disorder : A Randomized Trial.
作者: Jan Gryczynski.;Courtney D Nordeck.;Christopher Welsh.;Shannon G Mitchell.;Kevin E O'Grady.;Robert P Schwartz.
来源: Ann Intern Med. 2021年174卷7期899-909页
Hospitalized patients with comorbid substance use disorders (SUDs) are at high risk for poor outcomes, including readmission and emergency department (ED) use.
122. Food Insecurity and Weight Loss in an Underserved Primary Care Population: A Post Hoc Analysis of a Cluster Randomized Trial.
作者: Candice A Myers.;Corby K Martin.;John W Apolzan.;Connie L Arnold.;Terry C Davis.;William D Johnson.;Peter T Katzmarzyk.; .
来源: Ann Intern Med. 2021年174卷7期1032-1034页 123. A Double-Blind, Randomized, Placebo-Controlled Phase 1 Study of Ad26.ZIKV.001, an Ad26-Vectored Anti-Zika Virus Vaccine.
作者: Nadine C Salisch.;Kathryn E Stephenson.;Kristi Williams.;Freek Cox.;Leslie van der Fits.;Dirk Heerwegh.;Carla Truyers.;Marrit N Habets.;Diane G Kanjilal.;Rafael A Larocca.;Peter Abbink.;Jinyan Liu.;Lauren Peter.;Carlos Fierro.;Rafael A De La Barrera.;Kayvon Modjarrad.;Roland C Zahn.;Jenny Hendriks.;Conor P Cahill.;Maarten Leyssen.;Macaya Douoguih.;Johan van Hoof.;Hanneke Schuitemaker.;Dan H Barouch.
来源: Ann Intern Med. 2021年174卷5期585-594页
Zika virus (ZIKV) may cause severe congenital disease after maternal-fetal transmission. No vaccine is currently available.
124. The Use of Rifaximin in the Prevention of Overt Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt : A Randomized Controlled Trial.
作者: Christophe Bureau.;Dominique Thabut.;Caroline Jezequel.;Isabelle Archambeaud.;Louis D'Alteroche.;Sêbastien Dharancy.;Patrick Borentain.;Frédéric Oberti.;Aurélie Plessier.;Victor De Ledinghen.;Nathalie Ganne-Carrié.;Nicolas Carbonell.;Vanessa Rousseau.;Agnès Sommet.;Jean Marie Péron.;Jean Pierre Vinel.
来源: Ann Intern Med. 2021年174卷5期633-640页
The efficacy of rifaximin in the secondary prevention of overt hepatic encephalopathy (HE) is well documented, but its effectiveness in preventing a first episode in patients after transjugular intrahepatic portosystemic shunt (TIPS) has not been established.
125. The Effect of Preconception-Initiated Low-Dose Aspirin on Human Chorionic Gonadotropin-Detected Pregnancy, Pregnancy Loss, and Live Birth : Per Protocol Analysis of a Randomized Trial.
作者: Ashley I Naimi.;Neil J Perkins.;Lindsey A Sjaarda.;Sunni L Mumford.;Robert W Platt.;Robert M Silver.;Enrique F Schisterman.
来源: Ann Intern Med. 2021年174卷5期595-601页
A previous large randomized trial indicated that preconception-initiated low-dose aspirin (LDA) therapy did not have a positive effect on pregnancy outcomes. However, this trial was subject to nonadherence, which was not taken into account by the intention-to-treat approach.
126. The Effect of Flat Flexible Versus Stable Supportive Shoes on Knee Osteoarthritis Symptoms : A Randomized Trial.
作者: Kade L Paterson.;Kim L Bennell.;Penny K Campbell.;Ben R Metcalf.;Tim V Wrigley.;Jessica Kasza.;Rana S Hinman.
来源: Ann Intern Med. 2021年174卷4期462-471页
Experts recommend that persons with knee osteoarthritis wear stable supportive shoes; however, evidence suggests that flat flexible shoes may be more beneficial.
127. Stepped Exercise Program for Patients With Knee Osteoarthritis : A Randomized Controlled Trial.
作者: Kelli D Allen.;Sandra Woolson.;Helen M Hoenig.;Dennis Bongiorni.;James Byrd.;Kevin Caves.;Katherine S Hall.;Bryan Heiderscheit.;Nancy Jo Hodges.;Kim M Huffman.;Miriam C Morey.;Shalini Ramasunder.;Herbert Severson.;Courtney Van Houtven.;Lauren M Abbate.;Cynthia J Coffman.
来源: Ann Intern Med. 2021年174卷3期298-307页
Evidence-based models are needed to deliver exercise-related services for knee osteoarthritis efficiently and according to patient needs.
128. Comparison of Knowledge and Information-Seeking Behavior After General COVID-19 Public Health Messages and Messages Tailored for Black and Latinx Communities : A Randomized Controlled Trial.
作者: Marcella Alsan.;Fatima Cody Stanford.;Abhijit Banerjee.;Emily Breza.;Arun G Chandrasekhar.;Sarah Eichmeyer.;Paul Goldsmith-Pinkham.;Lucy Ogbu-Nwobodo.;Benjamin A Olken.;Carlos Torres.;Anirudh Sankar.;Pierre-Luc Vautrey.;Esther Duflo.
来源: Ann Intern Med. 2021年174卷4期484-492页
The paucity of public health messages that directly address communities of color might contribute to racial and ethnic disparities in knowledge and behavior related to coronavirus disease 2019 (COVID-19).
129. Hydroxychloroquine as Postexposure Prophylaxis to Prevent Severe Acute Respiratory Syndrome Coronavirus 2 Infection : A Randomized Trial.
作者: Ruanne V Barnabas.;Elizabeth R Brown.;Anna Bershteyn.;Helen C Stankiewicz Karita.;Christine Johnston.;Lorna E Thorpe.;Angelica Kottkamp.;Kathleen M Neuzil.;Miriam K Laufer.;Meagan Deming.;Michael K Paasche-Orlow.;Patricia J Kissinger.;Alfred Luk.;Kristopher Paolino.;Raphael J Landovitz.;Risa Hoffman.;Torin T Schaafsma.;Meighan L Krows.;Katherine K Thomas.;Susan Morrison.;Harald S Haugen.;Lara Kidoguchi.;Mark Wener.;Alexander L Greninger.;Meei-Li Huang.;Keith R Jerome.;Anna Wald.;Connie Celum.;Helen Y Chu.;Jared M Baeten.; .
来源: Ann Intern Med. 2021年174卷3期344-352页
Effective prevention against coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is currently limited to nonpharmaceutical strategies. Laboratory and observational data suggested that hydroxychloroquine had biological activity against SARS-CoV-2, potentially permitting its use for prevention.
130. The Effects of Four Doses of Vitamin D Supplements on Falls in Older Adults : A Response-Adaptive, Randomized Clinical Trial.
作者: Lawrence J Appel.;Erin D Michos.;Christine M Mitchell.;Amanda L Blackford.;Alice L Sternberg.;Edgar R Miller.;Stephen P Juraschek.;Jennifer A Schrack.;Sarah L Szanton.;Jeanne Charleston.;Melissa Minotti.;Sheriza N Baksh.;Robert H Christenson.;Josef Coresh.;Lea T Drye.;Jack M Guralnik.;Rita R Kalyani.;Timothy B Plante.;David M Shade.;David L Roth.;James Tonascia.; .
来源: Ann Intern Med. 2021年174卷2期145-156页
Vitamin D supplementation may prevent falls in older persons, but evidence is inconsistent, possibly because of dosage differences.
131. Effectiveness of Adding a Mask Recommendation to Other Public Health Measures to Prevent SARS-CoV-2 Infection in Danish Mask Wearers : A Randomized Controlled Trial.
作者: Henning Bundgaard.;Johan Skov Bundgaard.;Daniel Emil Tadeusz Raaschou-Pedersen.;Christian von Buchwald.;Tobias Todsen.;Jakob Boesgaard Norsk.;Mia M Pries-Heje.;Christoffer Rasmus Vissing.;Pernille B Nielsen.;Ulrik C Winsløw.;Kamille Fogh.;Rasmus Hasselbalch.;Jonas H Kristensen.;Anna Ringgaard.;Mikkel Porsborg Andersen.;Nicole Bakkegård Goecke.;Ramona Trebbien.;Kerstin Skovgaard.;Thomas Benfield.;Henrik Ullum.;Christian Torp-Pedersen.;Kasper Iversen.
来源: Ann Intern Med. 2021年174卷3期335-343页
Observational evidence suggests that mask wearing mitigates transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is uncertain if this observed association arises through protection of uninfected wearers (protective effect), via reduced transmission from infected mask wearers (source control), or both.
132. Long-Term Oncologic Outcomes After Laparoscopic Versus Open Resection for Colorectal Liver Metastases : A Randomized Trial.
作者: Davit L Aghayan.;Airazat M Kazaryan.;Vegar Johansen Dagenborg.;Bård I Røsok.;Morten Wang Fagerland.;Gudrun Maria Waaler Bjørnelv.;Ronny Kristiansen.;Kjersti Flatmark.;Åsmund Avdem Fretland.;Bjørn Edwin.; .
来源: Ann Intern Med. 2021年174卷2期175-182页
Despite the recent worldwide dissemination of laparoscopic liver surgery, no high-level evidence supports the oncologic safety of this approach.
133. Linked Color Imaging Focused on Neoplasm Detection in the Upper Gastrointestinal Tract : A Randomized Trial.
作者: Shoko Ono.;Kenro Kawada.;Osamu Dohi.;Shinji Kitamura.;Tomoyuki Koike.;Shinichiro Hori.;Hiromitsu Kanzaki.;Takahisa Murao.;Nobuaki Yagi.;Fumisato Sasaki.;Keiichi Hashiguchi.;Shiro Oka.;Kazuhiro Katada.;Ryo Shimoda.;Kazuhiro Mizukami.;Mitsuhiko Suehiro.;Toshihisa Takeuchi.;Shinichi Katsuki.;Momoko Tsuda.;Yuji Naito.;Tatsuyuki Kawano.;Ken Haruma.;Hideki Ishikawa.;Keita Mori.;Mototsugu Kato.; .
来源: Ann Intern Med. 2021年174卷1期18-24页
Linked color imaging (LCI) is a new image-enhanced endoscopy technique that allows users to recognize slight differences in mucosal color.
134. Physical Therapy Referral From Primary Care for Acute Back Pain With Sciatica : A Randomized Controlled Trial.
作者: Julie M Fritz.;Elizabeth Lane.;Molly McFadden.;Gerard Brennan.;John S Magel.;Anne Thackeray.;Kate Minick.;Whitney Meier.;Tom Greene.
来源: Ann Intern Med. 2021年174卷1期8-17页
Few studies have examined primary care management for acute sciatica, including referral to physical therapy.
135. Characteristics of COVID-19 in Homeless Shelters : A Community-Based Surveillance Study.
作者: Julia H Rogers.;Amy C Link.;Denise McCulloch.;Elisabeth Brandstetter.;Kira L Newman.;Michael L Jackson.;James P Hughes.;Janet A Englund.;Michael Boeckh.;Nancy Sugg.;Misja Ilcisin.;Thomas R Sibley.;Kairsten Fay.;Jover Lee.;Peter Han.;Melissa Truong.;Matthew Richardson.;Deborah A Nickerson.;Lea M Starita.;Trevor Bedford.;Helen Y Chu.; .
来源: Ann Intern Med. 2021年174卷1期42-49页
Homeless shelters are a high-risk setting for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission because of crowding and shared hygiene facilities.
136. Effectiveness of Curcuma longa Extract for the Treatment of Symptoms and Effusion-Synovitis of Knee Osteoarthritis : A Randomized Trial.
作者: Zhiqiang Wang.;Graeme Jones.;Tania Winzenberg.;Guoqi Cai.;Laura L Laslett.;Dawn Aitken.;Ingrid Hopper.;Ambrish Singh.;Robert Jones.;Jurgen Fripp.;Changhai Ding.;Benny Antony.
来源: Ann Intern Med. 2020年173卷11期861-869页
Current pharmacologic therapies for patients with osteoarthritis are suboptimal.
137. Three-Year Outcomes of Bariatric Surgery in Patients With Obesity and Hypertension : A Randomized Clinical Trial.
作者: Carlos A Schiavon.;Deepak L Bhatt.;Dimas Ikeoka.;Eliana V Santucci.;Renato Nakagawa Santos.;Lucas P Damiani.;Juliana D Oliveira.;Rachel Helena V Machado.;Helio Halpern.;Frederico L J Monteiro.;Patricia M Noujaim.;Ricardo V Cohen.;Marcio G de Souza.;Celso Amodeo.;Luiz A Bortolotto.;Otavio Berwanger.;Alexandre B Cavalcanti.;Luciano F Drager.
来源: Ann Intern Med. 2020年173卷9期685-693页
Midterm effects of bariatric surgery on patients with obesity and hypertension remain uncertain.
138. Effects of Interleukin-1β Inhibition on Incident Hip and Knee Replacement : Exploratory Analyses From a Randomized, Double-Blind, Placebo-Controlled Trial.
作者: Matthias Schieker.;Philip G Conaghan.;Linda Mindeholm.;Jens Praestgaard.;Daniel H Solomon.;Celeste Scotti.;Herman Gram.;Tom Thuren.;Ronenn Roubenoff.;Paul M Ridker.
来源: Ann Intern Med. 2020年173卷7期509-515页
Osteoarthritis is a common inflammatory disorder with no disease-modifying therapies. Whether inhibition of interleukin-1β (IL-1β) can reduce the consequences of large joint osteoarthritis is unclear.
139. Age- and Weight-Adapted Dose of Prasugrel Versus Standard Dose of Ticagrelor in Patients With Acute Coronary Syndromes : Results From a Randomized Trial.
作者: Maurizio Menichelli.;Franz-Josef Neumann.;Gjin Ndrepepa.;Katharina Mayer.;Jochen Wöhrle.;Isabell Bernlochner.;Gert Richardt.;Bernhard Witzenbichler.;Dirk Sibbing.;Senta Gewalt.;Dominick J Angiolillo.;Shqipdona Lahu.;Christian W Hamm.;Alexander Hapfelmeier.;Dietmar Trenk.;Karl-Ludwig Laugwitz.;Heribert Schunkert.;Stefanie Schüpke.;Adnan Kastrati.
来源: Ann Intern Med. 2020年173卷6期436-444页
The efficacy and safety of a reduced dose of prasugrel versus a standard dose of ticagrelor in elderly patients or those with a low body weight presenting with an acute coronary syndrome (ACS) are unknown.
140. Hydroxychloroquine in Nonhospitalized Adults With Early COVID-19 : A Randomized Trial.
作者: Caleb P Skipper.;Katelyn A Pastick.;Nicole W Engen.;Ananta S Bangdiwala.;Mahsa Abassi.;Sarah M Lofgren.;Darlisha A Williams.;Elizabeth C Okafor.;Matthew F Pullen.;Melanie R Nicol.;Alanna A Nascene.;Kathy H Hullsiek.;Matthew P Cheng.;Darlette Luke.;Sylvain A Lother.;Lauren J MacKenzie.;Glen Drobot.;Lauren E Kelly.;Ilan S Schwartz.;Ryan Zarychanski.;Emily G McDonald.;Todd C Lee.;Radha Rajasingham.;David R Boulware.
来源: Ann Intern Med. 2020年173卷8期623-631页
No effective oral therapy exists for early coronavirus disease 2019 (COVID-19).
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