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1208. Image-Assısted Pleural Needle Biopsy or Medical Thoracoscopy: Which Method for Which Patient? A Randomızed Controlled Trial.
作者: Muzaffer Metintas.;Guntulu Ak.;Huseyin Yildirim.;Emine Dundar.;Nevin Aydin.;Sinan Erginel.;Fusun Alatas.;Senay Yilmaz.;Selma Metintas.
来源: Chest. 2024年166卷2期405-412页
Image-guided or assisted needle biopsies and the increasing use of medical thoracoscopy (MT) have increased the diagnostic accuracy of pleural diseases significantly. However, no consensus exists regarding which patients with pleural effusion should undergo MT and which patients should undergo image-guided or assisted needle biopsy as the first procedure to ensure greater diagnostic accuracy.
1210. Flow Cytometry as an Alternative to Microscopy for the Differentiation of BAL Fluid Leukocytes.
作者: Kai Bratke.;Martin Weise.;Paul Stoll.;J Christian Virchow.;Marek Lommatzsch.
来源: Chest. 2024年166卷4期793-801页
Microscopy is currently the gold standard to differentiate BAL fluid (BALF) leukocytes. However, local expertise for microscopic BALF leukocyte differentiation is often unavailable in clinical practice.
1211. Changes in Spirometry Interpretative Strategies: Implications for Classifying COPD and Predicting Exacerbations.
作者: J Henry Brems.;Aparna Balasubramanian.;Sarath Raju.;Nirupama Putcha.;Ashraf Fawzy.;Nadia N Hansel.;Robert A Wise.;Meredith C McCormack.
来源: Chest. 2024年166卷2期294-303页
Recent guidelines for spirometry interpretation recommend both race-neutral reference equations and use of z score thresholds to define severity of airflow obstruction.
1212. Relationship Between Lung Volumes and Heterogeneity in the Response to Elexacaftor/Tezacaftor/Ivacaftor in Patients With Cystic Fibrosis and Advanced Lung Disease.
作者: Andrea Gramegna.;Gianfranco Alicandro.;Chiara Premuda.;Francesca Lucca.;Lucia Pinali.;Mariangela Retucci.;Valentina Vespro.;Maria Carmela Andrisani.;Gianpaolo Carraffiello.;Francesco Amati.;Sonia Volpi.;Stefano Aliberti.;Marco Cipolli.;Francesco Blasi.
来源: Chest. 2024年166卷3期433-441页
The effects of elexacaftor/tezacaftor/ivacaftor (ETI) on respiratory outcomes for people with cystic fibrosis (CF) were demonstrated by several clinical trials, mainly based on simple spirometry. However, gains in lung function may vary greatly between patients, and predictors of FEV1 change after treatment have yet to be defined.
1213. The Association of Pregnancy With Outcomes Among Critically Ill Reproductive-Aged Women: A Propensity Score-Matched Retrospective Cohort Analysis.
作者: Rachel Kohn.;Deepshikha C Ashana.;Kelly C Vranas.;Elizabeth M Viglianti.;Katrina Hauschildt.;Catherine Chen.;Emily A Vail.;Leslie Moroz.;Hayley B Gershengorn.
来源: Chest. 2024年166卷4期765-777页
The maternal mortality rate in the United States is unacceptably high. However, the relative contribution of pregnancy to these outcomes is unknown. Studies comparing outcomes among pregnant vs nonpregnant critically ill patients show mixed results and are limited by small sample sizes.
1214. The Role of Pediatric Psychologists in Critical Care: Lessons Learned and Future Directions in Integrating Mental Health Care Into PICUs.
作者: Kristin Canavera.;Patricia Marik.;Nicole M Schneider.;Jacquelyn Smith.
来源: Chest. 2024年166卷3期511-516页
Pediatric psychologists are essential staff in the PICU. Their role in caring for critically ill children aligns with clinical practice guidelines for the mental health care needs of this population of patients. This article highlights the role of pediatric psychology in the PICU through illustrative case examples. We discuss lessons learned and future directions for the development and provision of mental health services in PICUs. We address relevant ways for critical care providers to understand the importance of evidence-based psychological care and advocate for the inclusion of psychologists on multidisciplinary PICU teams. As the critical care field continues to focus on an improved understanding of post-intensive care syndrome in pediatrics and the psychological needs of critical care patients, it will be important to consider the vital roles of psychologists and to advocate for improved integration of mental health care in PICUs.
1215. The Association Between Sputum Culture Conversion and Mortality in Cavitary Mycobacterium avium Complex Pulmonary Disease.
作者: Ju Kwang Lee.;Seonok Kim.;Yong Pil Chong.;Hyun Joo Lee.;Tae Sun Shim.;Kyung-Wook Jo.
来源: Chest. 2024年166卷3期442-451页
The association between treatment outcome and the mortality of patients with Mycobacterium avium complex pulmonary disease (MAC-PD) with cavitary lesions is unclear. This article assessed the impact of culture conversion on mortality in patients with cavitary MAC-PD.
1216. Comparison of Contemporary Risk Scores in All Groups of Pulmonary Hypertension: A Pulmonary Vascular Research Institute GoDeep Meta-Registry Analysis.
作者: Athiththan Yogeswaran.;Henning Gall.;Meike Fünderich.;Martin R Wilkins.;Luke Howard.;David G Kiely.;Allan Lawrie.;Paul M Hassoun.;Yuriy Sirenklo.;Olena Torbas.;Andrew J Sweatt.;Roham T Zamanian.;Paul G Williams.;Marlize Frauendorf.;Alexandra Arvanitaki.;George Giannakoulas.;Khaled Saleh.;Hani Sabbour.;Hector R Cajigas.;Robert Frantz.;Imad Al Ghouleh.;Stephen Y Chan.;Evan Brittain.;Jeffrey S Annis.;Antonella Pepe.;Stefano Ghio.;Stylianos Orfanos.;Anastasia Anthi.;Raphael W Majeed.;Jochen Wilhelm.;Hossein Ardeschir Ghofrani.;Manuel J Richter.;Friedrich Grimminger.;Sandeep Sahay.;Khodr Tello.;Werner Seeger.; .
来源: Chest. 2024年166卷3期585-603页
Pulmonary hypertension (PH) is a heterogeneous disease with a poor prognosis. Accurate risk stratification is essential for guiding treatment decisions in pulmonary arterial hypertension (PAH). Although various risk models have been developed for PAH, their comparative prognostic potential requires further exploration. Additionally, the applicability of risk scores in PH groups beyond group 1 remains to be investigated.
1217. Laryngeal Dysfunction Manifesting as Chronic Refractory Cough and Dyspnea: Laryngeal Physiology in Respiratory Health and Disease.
Laryngeal dysfunction as a cause of chronic refractory cough and episodic dyspnea is often missed, which results in unnecessary testing and delays in diagnosis. Understanding laryngeal roles in breathing and airway protection can help to appreciate the propensity to laryngeal dysfunction with aging, chronic lung disease, and sleep apnea.
1218. Nationwide Increasing Incidence of Nontuberculous Mycobacterial Diseases Among Adults in Denmark: Eighteen Years of Follow-Up.
作者: Andreas A Pedersen.;Anders Løkke.;Andreas Fløe.;Rikke Ibsen.;Isik S Johansen.;Ole Hilberg.
来源: Chest. 2024年166卷2期271-280页
The epidemiology of nontuberculous mycobacteria (NTM) infections is not well described. In this study, we sought to determine the incidence and prevalence of NTM infections and focus on social risk factors. In addition, we describe people with pulmonary and extrapulmonary NTM.
1219. Rates and Risk Factors of Progression in Patients With Nontuberculous Mycobacterial Pulmonary Disease: Secondary Analysis of a Prospective Cohort Study.
作者: Kwonhyung Hyung.;Sung-A Kim.;Joong-Yub Kim.;Nakwon Kwak.;Jae-Joon Yim.
来源: Chest. 2024年166卷3期452-460页
The clinical course of nontuberculous mycobacterial pulmonary disease (NTM-PD) is varied, and a watchful waiting management strategy is appropriate for a subset of patients. Understanding disease progression and risk factors for progression is essential for deciding on an appropriate follow-up strategy.
1220. Distribution of Acute and Chronic Kidney Disease Across Clinical Phenotypes for Sepsis.
作者: Luca Molinari.;Gaspar Del Rio-Pertuz.;Priyanka Priyanka.;Ali Smith.;Joseph C Maggiore.;Jason Kennedy.;Hernando Gomez.;Christopher W Seymour.;John A Kellum.; .
来源: Chest. 2024年166卷3期480-490页
Sepsis is the most common cause of acute kidney injury (AKI) in critically ill patients. Four phenotypes (α, β, γ, δ) for sepsis, which have different outcomes and responses to treatment, were described using routine clinical data in the electronic health record.
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