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101. Timing of endoscopy in cirrhotic patients with acute variceal bleeding: a multicenter cohort study.
作者: Javier Tejedor-Tejada.;Benito Hermida.;Cristina Camblor.;Samuel Robles.;Mohamed Emara.;Salem Y Mohamed.;Jose M Perez-Pariente.
来源: Minerva Gastroenterol (Torino). 2025年
The optimal timing of endoscopy in cirrhotic patients with acute variceal bleeding (AVB) remains uncertain. The study aimed to determine whether the timing of endoscopy affects short-term outcomes in patients with AVB.
102. AGA Clinical Practice Update on Endoscopic Resection for Early Colorectal Cancer: Commentary.
作者: Saowanee Ngamruengphong.;Mohamed O Othman.;Andrew Y Wang.;Dennis Yang.
来源: Gastroenterology. 2025年
T1 colorectal cancer (CRC), defined as tumor invasion confined to the submucosa, has traditionally been managed by surgery. Advances in endoscopic resection techniques, coupled with an improved understanding of tumor biology and risk of lymph node metastasis and recurrence, have expanded our treatment armamentarium for these lesions. The purpose of this American Gastroenterological Association (AGA) Clinical Practice Update Expert Commentary is to review the definition of T1 CRC, discuss the role of endoscopic resection for these lesions, review factors associated with risk of recurrence and metastasis, and discuss post-resection management, including surveillance or adjuvant surgery. The target audience for this commentary includes primary care, gastroenterology, pathology, and surgical health care professionals.
103. Comparative Efficacy of Advanced Therapies for Management of Moderate-to-Severe Crohn's Disease: 2025 AGA Evidence Synthesis.
作者: Siddharth Singh.;M Hassan Murad.;Yuhong Yuan.;Ashwin N Ananthakrishnan.;Benjamin Click.;Gaurav Syal.;John P Haydek.;Manasi Agrawal.;Michael D Kappelman.;James D Lewis.;Frank I Scott.
来源: Gastroenterology. 2025年
We performed an updated systematic review and network meta-analysis to inform the 2025 American Gastroenterological Association Clinical Guidelines on the management of moderate-to-severe Crohn's disease (CD).
104. AGA Clinical Practice Update on the Management of Ascites, Volume Overload, and Hyponatremia in Cirrhosis: Expert Review.
The purpose of this American Gastroenterological Association (AGA) Institute Clinical Practice Update (CPU) is to summarize the available evidence and offer expert Best Practice Advice (BPA) on the management of ascites, hepatic hydrothorax, volume overload, and hyponatremia in patients with cirrhosis.
106. Hemodynamic Status as a Determinant Factor of Optimal Endoscopy Timing in Upper Gastrointestinal Bleeding: Results From an International Survey of 533 Clinicians.
作者: Mahmoud Obeidat.;Diana-Elena Floria.;Brigitta Teutsch.;Zsolt Abonyi-Tóth.;Péter Hegyi.;Bálint Erőss.; .
来源: Gastroenterology. 2025年 107. Reduced Esophageal Hypervigilance and Symptom-Specific Anxiety in Barrett's Esophagus: A Deficient Alarm Signal for Gastroesophageal Reflux Disease-Associated Mucosal Injury.
作者: Ming-Wun Wong.;Shih-Hsuan Hsiao.;Jen-Hung Wang.;Chandra Prakash Gyawali.;Peir-Rong Chen.;Chien-Lin Chen.
来源: Gastroenterology. 2025年 114. Negative pressure wound therapy in high-risk gastrointestinal surgery: a retrospective cohort study on postoperative complications.
Surgical site infections (SSIs) are a significant cause of morbidity in colorectal surgeries, mainly due to the contaminated nature of these procedures. Traditional wound management techniques have limitations, leading to prolonged hospital stays and increased healthcare costs. Negative pressure wound therapy (NPWT) has emerged as an advanced method for managing surgical wounds, promoting faster healing by enhancing tissue perfusion, reducing edema, and managing wound exudate. This retrospective cohort study aims to compare the outcomes of NPWT with those of conventional wound care in patients undergoing high-risk gastrointestinal surgeries.
115. Bioinformatics analysis and in vitro studies identify COX7C as a prognostic predictor in gastric adenocarcinoma.
作者: Conglai Shi.;Qiang Wang.;Xin Zhang.;Weiguo Wang.;Wei Wang.;Ziran Wei.;Yue Liu.
来源: BMC Gastroenterol. 2025年25卷1期741页
Stomach adenocarcinoma (STAD) remains a significant threat to human health. This study sought to discover clinically relevant biomarkers for STAD by integrating bioinformatics analysis and in vitro experimental methods.
116. Efficacy of hydration combined with rectal non-steroidal anti-inflammatory drugs (NSAIDs) versus NSAIDs alone for the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis: a systematic review and meta-analysis of randomized controlled trials.
作者: Huimin Li.;Changfeng Miao.;Wei Fang.;Yuan Deng.;Xiong Li.;Ting Du.;Hongwei Tian.
来源: BMC Gastroenterol. 2025年25卷1期738页
The most prevalent complication of endoscopic retrograde cholangiopancreatography (ERCP) is post-ERCP acute pancreatitis (PEP). Both hydration and rectal non-steroidal anti-inflammatory drugs (NSAIDs) can effectively prevent PEP; however, there is currently no consensus on whether combination therapy is more effective than either intervention alone.
117. Development and validation of a novel nomogram incorporating psychosocial factors for predicting hypoglycemia during perioperative period of digestive endoscopy (DREAM-Hypo Model).
Perioperative hypoglycemia during digestive endoscopy poses significant risks, with reported incidence rates of 6.75-18.70%. Traditional models focus on metabolic factors, while psychosocial stressors (anxiety, poor sleep quality) may exacerbate risk through neuroendocrine dysregulation. This study aims to develop a novel nomogram (DREAM-Hypo Model) integrating psychosocial, clinical, and metabolic predictors for hypoglycemia risk stratification.
118. Serum markers and gastric cancer: an umbrella review.
作者: Afra Darvishi.;Amirhosein Dadashzadeh Asl.;Pouya Golshaniniya.;Ali Alipour.;Amirreza Naseri.;Sina Hamzehzadeh.;Hanieh Salehi-Pourmehr.
来源: BMC Gastroenterol. 2025年25卷1期737页
Early detection of gastric cancer (GC) is crucial for lowering the mortality risk and health burden. Since various biomarkers have been studied for the early diagnosis of GC, this umbrella focuses on the serum markers valuable in GC, for whether detecting or predicting the risk.
119. Association of cardiometabolic risk burden with gastrointestinal bleeding in aspirin users.
作者: Yajing Wei.;Jiamin Yan.;Ziting Gao.;Hongye Wei.;Ziyi Qiu.;Jun Xiao.;Wuqing Huang.
来源: BMC Gastroenterol. 2025年25卷1期736页
Aspirin is widely used in patients with ischemic cardiovascular diseases, most of whom have cardiometabolic disorders. This study aimed to investigate the impact of cardiometabolic risk burden on first gastrointestinal (GI) bleeding in aspirin users.
120. Population stratified differences between ATG16L1 rs2241880 polymorphism with Crohn's disease risk: a systematic review and meta-analysis.
ATG16L1 rs2241880 (T300A), a single-nucleotide variant, plays a controversial role in the development of Crohn's disease (CD).
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