101. A 64-Year-Old Man With Ocular Albinism, Interstitial Lung Disease, and Clubbing.
作者: Mateus Fernandes.;Zachary Greenstein.;Nicole Oslance.;Ashwin Varkey.;Kevin Shayani.;Simon Meredith.;Stephen Machnicki.
来源: Chest. 2026年169卷2期e45-e49页
A 64-year-old man, originally from Puerto Rico, was referred for suspected interstitial lung disease based on incidental chest imaging findings. He had no respiratory concerns such as cough or dyspnea. He had preserved exercise tolerance and walked multiple city blocks without stopping.
105. Reducing Inhaler Waste and Costs Through Sustainable Interventions.
作者: Marianne Laguë.;Isabelle Giroux.;Alexandre Sanctuaire.;Julie Racicot.;Cassiopée Gagnon-Paradis.;François Maltais.;Andréanne Côté.;Krystelle Godbout.
来源: Chest. 2026年169卷2期326-328页 111. Daily Physical Activity in Pulmonary Arterial Hypertension: Insights From a Multicenter Longitudinal Trial Using Accelerometry.
作者: Jasleen Minhas.;Haochang Shou.;Nadine Al-Naamani.;Rui Feng.;Roham Zamanian.;Todd Bull.;Murali Chakinala.;Anna Hemnes.;Jude Moutchia.;Stephen C Mathai.;Susan Ellenberg.;Corey Ventetuolo.;Steven M Kawut.
来源: Chest. 2026年
Pulmonary arterial hypertension (PAH) is a progressive disease associated with high morbidity and mortality. Traditional assessments such as the 6-minute walk distance (6MWD) may not adequately capture daily physical activity or patient experience in real-world settings.
112. Outcomes of Severe Mpox Admitted to ICUs at Two Large New York City Health Systems, 2022-2024.
作者: Anthony J Lo Piccolo.;Shane Antoinette Arante.;Justin Chan.;Kathryn Jano.;Madeline A DiLorenzo.;Melissa Achenbaum.;Regan Britt.;David Butler.;Radu Postelnicu.;Erin McGuire.;Vikramjit Mukherjee.
来源: Chest. 2026年 113. Judgment Under Uncertainty: A Case-Based Analysis of Cognitive Bias in Extracorporeal Membrane Oxygenation Candidacy Decision-Making.
There is no consensus for identifying ideal candidates for extracorporeal membrane oxygenation (ECMO), a life-sustaining technology that can supply oxygenated blood to a patient whose heart and/or lungs are not properly functioning. Without clear and standardized guidelines, the decision about who to cannulate often falls upon one or several clinicians who weigh the procedure's risks and benefits. Limited data, and therefore substantial clinical judgment, guides ECMO candidacy determination, rendering the process particularly susceptible to heuristic-based decision-making and cognitive biases resulting from mental shortcuts. This can lead to candidates being inappropriately accepted or declined for ECMO and suboptimal allocation of a limited resource. This article presents a hypothetical case based on real clinical scenarios highlighting the impact that cognitive biases may play in ECMO candidacy and discussing their potential harms. We argue that ECMO candidacy determination is especially vulnerable to cognitive biases and offer several ways to mitigate their influence on candidacy selection. Our aim was to stimulate the recognition and mitigation of cognitive bias in ECMO deliberations as one step toward the standardization of ECMO candidacy determinations, with the goal of achieving more equitable and effective care for patients who would most benefit from this technology.
114. Sex Does Not Modify Prediction of Asthma Attacks by Clinical Risk Factors and Type 2 Biomarkers.
作者: Sebastian Riemann.;Fleur L Meulmeester.;Samuel Mailhot-Larouche.;Sanjay Ramakrishnan.;Michael E Wechsler.;Jonathan Corren.;Sarah E Diver.;Christopher E Brightling.;Mario Castro.;Nicola A Hanania.;David J Jackson.;Neil Martin.;Annette Laugerud.;Deborah Clarke.;Alison Moore.;Megan E Hardin.;Cecile T J Holweg.;Subhashini Allu.;Timothy S C Hinks.;Richard W Beasley.;Jacob K Sont.;Ewout W Steyerberg.;Ian D Pavord.;Guy Brusselle.;Simon Couillard.; .
来源: Chest. 2026年
Multiple clinical and inflammatory risk factors for asthma attacks have been identified, including attack history, comorbidities, blood eosinophil count (BEC), and exhaled nitric oxide (Feno). However, the impact of sex on their prognostic value is unclear.
115. Updates on Rhabdomyolysis: A Clinically Oriented Narrative Review.
作者: Quinlan Richert.;Nicholas Miller.;Shane Cameron.;Bryce Barr.;Joel Nkosi.;Aditya Sharma.
来源: Chest. 2026年
Rhabdomyolysis is the clinical syndrome resulting from the release of skeletal muscle cellular contents into the bloodstream, typically manifesting as limb weakness, myalgias, swelling, myoglobinuria, electrolyte abnormalities, and, critically, acute kidney injury (AKI). Recognition of this complex of clinical and biochemical features is necessary for accurate diagnosis and subsequent management.
116. Pulmonary Hypertension Prevalence and Significance in Lung Transplant Recipients With Cystic Fibrosis and Non-Cystic Fibrosis Bronchiectasis.
作者: Abhimanyu Chandel.;Simon Turkington.;Christopher S King.;Anju Singhal.;Alan Nyquist.;A Whitney Brown.;Steven D Nathan.
来源: Chest. 2026年
Pulmonary hypertension (PH) is a complication of advanced cystic fibrosis (CF) and non-cystic fibrosis bronchiectasis (n-CFB). The prevalence and after transplantation prognostic significance of PH in CF and n-CFB remain poorly defined.
117. Interactive Pathways of Key Prognostic Factors in Severe Asthma: A Bayesian Network Comparison of Clinical Trials and Real-World Data.
作者: Chandra Prakash Yadav.;Laura Huey Mien Lim.;David Price.;Rupsa Roy.;Juang Yah Ru.;Richard Beasley.;Christer Janson.;Mariko Siyue Koh.;Eileen Wang.;Michael E Wechsler.;David J Jackson.;John Busby.;Liam G Heaney.;Paul E Pfeffer.;Bassam Mahboub.;Diahn-Warng Perng Steve.;Borja G Cosio.;Luis Perez-de-Llano.;Riyad Al-Lehebi.;Désirée Larenas-Linnemann.;Mona Al-Ahmad.;Chin Kook Rhee.;Takashi Iwanaga.;Enrico Heffler.;Giorgio Walter Canonica.;Richard Costello.;Nikolaos G Papadopoulos.;Andriana I Papaioannou.;Celeste M Porsbjerg.;Carlos A Torres-Duque.;George C Christoff.;Todor A Popov.;Mark Hew.;Matthew Peters.;Peter G Gibson.;Jorge Maspero.;Celine Bergeron.;Saraid Cerda.;Elvia Angelica Contreras.;Wenjia Chen.
来源: Chest. 2026年
The way in which risk predictors combine and contribute to severe asthma exacerbations may differ between clinical trials and real-world settings.
118. Twelve-Month Follow-Up and Economic Evaluation of an Alternative Care Provider Clinic for Severe Sleep-Disordered Breathing.
作者: Erika D Penz.;Ada Ip-Buting.;Willis H Tsai.;Maria J Santana.;W Ward Flemons.;Kristin L Fraser.;Sachin R Pendharkar.
来源: Chest. 2026年
Use of nonphysician alternative care providers (ACPs) can improve timely access to sleep-disordered breathing (SDB) care, and previous studies have demonstrated beneficial short-term clinical outcomes. Longer-term clinical and economic impacts of an ACP model for patients with severe SDB have not been evaluated.
119. The Impact of the 2023 American Cancer Society Screening Recommendations on Racial, Ethnic, and Sex Disparities in Lung Cancer Screening Eligibility.
作者: Adoma Manful.;Nikita Amanna.;S Lani Park.;Jessica L Petrick.;Lynn Rosenberg.;Hilary Tindle.;Julie Palmer.;Lynne Wilkens.;Loïc Le Marchand.;Melinda C Aldrich.;Jeffrey D Blume.
来源: Chest. 2026年
Because lung cancer risk remains elevated beyond 15 years after smoking cessation, the American Cancer Society (ACS) recommended in 2023 to remove the quit duration criterion from the United States Preventive Services Taskforce (USPSTF) lung cancer screening guidelines.
120. Exacerbation Risk by Chronic Proton Pump Inhibitor Use in Obstructive Lung Diseases.
Previous studies have shown inconsistent results regarding the use of proton pump inhibitor (PPIs) and the risk on exacerbations in patients with chronic obstructive airway diseases (COADs).
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