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1101. Lung deposition of fenoterol and flunisolide delivered using a novel device for inhaled medicines: comparison of RESPIMAT with conventional metered-dose inhalers with and without spacer devices.
To compare lung deposition of fenoterol or flunisolide administered from a novel, multidose inhalation device delivering liquid droplets (RESPIMAT; Boehringer Ingelheim Ltd; Bracknell, UK) or from conventional metered-dose inhalers (MDIs) with and without spacers.
1102. A randomized clinical trial comparing an extended-use hygroscopic condenser humidifier with heated-water humidification in mechanically ventilated patients.
作者: M H Kollef.;S D Shapiro.;V Boyd.;P Silver.;B Von Harz.;E Trovillion.;D Prentice.
来源: Chest. 1998年113卷3期759-67页
To determine the safety and cost-effectiveness of mechanical ventilation with an extended-use hygroscopic condenser humidifier (Duration; Nellcor Puritan-Bennett; Eden Prairie, Minn) compared with mechanical ventilation with heated-water humidification.
1103. Use of conventional and self-adjusting nasal continuous positive airway pressure for treatment of severe obstructive sleep apnea syndrome: a comparative study.
作者: M Konermann.;B M Sanner.;M Vyleta.;F Laschewski.;J Groetz.;A Sturm.;W Zidek.
来源: Chest. 1998年113卷3期714-8页
To compare conventional and self-adjusting nasal continuous positive airway pressure (nCPAP) therapy in patients with severe obstructive sleep apnea syndrome with respect to suppression of respiratory disturbances, quality of sleep, mean mask pressure, and patient compliance.
1104. The effect of of glucocorticoids on grain dust-induced airway disease.
作者: J F Trapp.;J L Watt.;K L Frees.;T J Quinn.;M W Nonnenmann.;D A Schwartz.
来源: Chest. 1998年113卷2期505-13页
To determine the effect of glucocorticoids on grain dust-induced airflow obstruction and airway inflammation.
1105. Proventil HFA and ventolin have similar safety profiles during regular use.
作者: D G Tinkelman.;E R Bleecker.;J Ramsdell.;B P Ekholm.;N M Klinger.;G L Colice.;H B Slade.
来源: Chest. 1998年113卷2期290-6页
As a secondary objective to a long-term study evaluating the bronchodilator effectiveness of Proventil HFA (albuterol), to assess the safety of Proventil HFA, Ventolin, and hydrofluoroalkane 134a (HFA-134a) placebo over 12 weeks of regular dosing.
1106. Proventil HFA provides bronchodilation comparable to ventolin over 12 weeks of regular use in asthmatics.
作者: E R Bleecker.;D G Tinkelman.;J Ramsdell.;B P Ekholm.;N M Klinger.;G L Colice.;H B Slade.
来源: Chest. 1998年113卷2期283-9页
To compare the bronchodilator effectiveness of albuterol reformulated in the chlorofluorocarbon-free propellant hydrofluoroalkane (HFA)134a (Proventil HFA) to that of Ventolin and HFA placebo over 12 weeks of regular dosing.
1107. A 1-year community-based health economic study of ciprofloxacin vs usual antibiotic treatment in acute exacerbations of chronic bronchitis: the Canadian Ciprofloxacin Health Economic Study Group.
作者: R Grossman.;J Mukherjee.;D Vaughan.;C Eastwood.;R Cook.;J LaForge.;N Lampron.
来源: Chest. 1998年113卷1期131-41页
To evaluate the costs, consequences, effectiveness, and safety of ciprofloxacin vs standard antibiotic care in patients with an initial acute exacerbation of chronic bronchitis (AECB) as well as recurrent AECBs over a 1-year period.
1108. Concomitant administration of low-dose prednisolone protects against in vivo beta2-adrenoceptor subsensitivity induced by regular formoterol.
To assess whether concomitant administration of low-dose prednisolone (PRED) with regular inhaled formoterol (FM) might prevent the occurrence of beta2-adrenoceptor (beta2-AR) tachyphylaxis.
1109. Nebulized lidocaine administered to infants and children undergoing flexible bronchoscopy.
The purpose of this study was to evaluate the safety and efficacy of nebulized lidocaine hydrochloride as a topical anesthetic for use during flexible bronchoscopy in infants and children.
1110. The effect of a peak flow-based action plan in the prevention of exacerbations of asthma.
To determine the effect of a symptom-based and a peak flow-based action plan in preventing acute exacerbations in subjects with poorly controlled asthma.
1111. Routine nebulized ipratropium and albuterol together are better than either alone in COPD. The COMBIVENT Inhalation Solution Study Group.
来源: Chest. 1997年112卷6期1514-21页
We compared the long-term safety and efficacy of the combination ipratropium bromide (IB) and albuterol sulfate (ALB) inhalation solution with that of each separate component using three-times-daily administration.
1112. Nebulized wet aerosol treatment in emergency department--is it essential? Comparison with large spacer device for metered-dose inhaler.
To determine the efficacy of a metered-dose inhaler (MDI) with a large spacer device as compared to nebulized wet aerosols in the treatment of an unselected population with severe airflow limitation.
1113. Breathing pattern and arterial blood gases during Nd-YAG laser photoresection of endobronchial lesions under general anesthesia: use of negative pressure ventilation: a preliminary study.
作者: M Vitacca.;G Natalini.;S Cavaliere.;E Clini.;P Foccoli.;A Candiani.;N Ambrosino.
来源: Chest. 1997年112卷6期1466-73页
To evaluate the efficacy of negative pressure ventilation (NPV) in avoiding or reducing apneas and related hypoxemia and respiratory acidosis during laser therapy (LT) of endobronchial lesions.
1114. Diagnostic accuracy of transbronchial biopsy in acute farmer's lung disease.
To evaluate whether transbronchial biopsy (TBB) is useful for the diagnosis of acute farmer's lung (FL) by calculating the likelihood ratios (LHRs) of (1) simple pathologic criteria and (2) an overall assessment of the biopsy specimens.
1115. A randomized, controlled study of the 1-hour and 24-hour effects of inhaled nitric oxide therapy in children with acute hypoxemic respiratory failure.
To determine whether 24 h of inhaled nitric oxide improves oxygenation greater than conventional therapy alone in children with acute hypoxemic respiratory failure.
1116. Evaluation of corticotropin releasing factor stimulation and basal markers of hypothalamic-pituitary-adrenal axis suppression in asthmatic patients.
The aim of our study was to compare basal unstimulated levels of plasma cortisol and adrenocorticotropic hormone (ACTH) with stimulated levels produced by the corticotropin releasing factor (CRF) test in asthmatics taking high-dose inhaled steroid therapy. In theory, the CRF test would appear to be a suitable replacement for tetracosactrin (cosyntropin) (synthetic ACTH) as a test of hypothalamic-pituitary-adrenal (HPA) axis suppression.
1117. Influenza virus vaccination of patients with chronic lung disease.
作者: G J Gorse.;E E Otto.;C C Daughaday.;F K Newman.;C S Eickhoff.;D C Powers.;R H Lusk.
来源: Chest. 1997年112卷5期1221-33页
To evaluate the safety of, and mucosal and systemic immune responses induced by two influenza virus vaccine regimens in subjects with COPD.
1118. Postoperative radiotherapy in radically resected non-small cell lung cancer.
作者: R Mayer.;F M Smolle-Juettner.;D Szolar.;G F Stuecklschweiger.;F Quehenberger.;G Friehs.;A Hackl.
来源: Chest. 1997年112卷4期954-9页
To evaluate the value of adjuvant postoperative external-beam radiation (EBR) in patients with radically resected non-small cell lung cancer (NSCLC) pT1-3 pN0-2 compared to patients with resected NSCLC without adjuvant EBR.
1119. A prospective, randomized comparison of an in-line heat moisture exchange filter and heated wire humidifiers: rates of ventilator-associated early-onset (community-acquired) or late-onset (hospital-acquired) pneumonia and incidence of endotracheal tube occlusion.
To compare the performance of an in-line heat moisture exchanging filter (HMEF) (Pall BB-100; Pall Corporation; East Hills, NY) to a conventional heated wire humidifier (H-wH) (Marquest Medical Products Inc., Englewood, Colo) in the mechanical ventilator circuit on the incidence of ventilator-associated pneumonia (VAP) and the rate of endotracheal tube occlusion.
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