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81. How long does a hip replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow-up.
作者: Jonathan T Evans.;Jonathan P Evans.;Robert W Walker.;Ashley W Blom.;Michael R Whitehouse.;Adrian Sayers.
来源: Lancet. 2019年393卷10172期647-654页
Total hip replacement is a common and highly effective operation. All hip replacements would eventually fail if in situ long enough and it is important that patients understand when this might happen. We aimed to answer the question: how long does a hip replacement last?
82. Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses.
作者: Caroline Ovadia.;Paul T Seed.;Alexandros Sklavounos.;Victoria Geenes.;Chiara Di Ilio.;Jenny Chambers.;Katherine Kohari.;Yannick Bacq.;Nuray Bozkurt.;Romana Brun-Furrer.;Laura Bull.;Maria C Estiú.;Monika Grymowicz.;Berrin Gunaydin.;William M Hague.;Christian Haslinger.;Yayi Hu.;Tetsuya Kawakita.;Ayse G Kebapcilar.;Levent Kebapcilar.;Jūratė Kondrackienė.;Maria P H Koster.;Aneta Kowalska-Kańka.;Limas Kupčinskas.;Richard H Lee.;Anna Locatelli.;Rocio I R Macias.;Hanns-Ulrich Marschall.;Martijn A Oudijk.;Yael Raz.;Eli Rimon.;Dan Shan.;Yong Shao.;Rachel Tribe.;Valeria Tripodi.;Cigdem Yayla Abide.;Ilter Yenidede.;Jim G Thornton.;Lucy C Chappell.;Catherine Williamson.
来源: Lancet. 2019年393卷10174期899-909页
Intrahepatic cholestasis of pregnancy is associated with adverse perinatal outcomes, but the association with the concentration of specific biochemical markers is unclear. We aimed to quantify the adverse perinatal effects of intrahepatic cholestasis of pregnancy in women with increased serum bile acid concentrations and determine whether elevated bile acid concentrations were associated with the risk of stillbirth and preterm birth.
83. Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26 randomised trials.
Increasing the dose intensity of cytotoxic therapy by shortening the intervals between cycles, or by giving individual drugs sequentially at full dose rather than in lower-dose concurrent treatment schedules, might enhance efficacy.
84. Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials.
Statin therapy has been shown to reduce major vascular events and vascular mortality in a wide range of individuals, but there is uncertainty about its efficacy and safety among older people. We undertook a meta-analysis of data from all large statin trials to compare the effects of statin therapy at different ages.
85. Pharmacological treatments for generalised anxiety disorder: a systematic review and network meta-analysis.
作者: April Slee.;Irwin Nazareth.;Paulina Bondaronek.;Yifeng Liu.;Zhihang Cheng.;Nick Freemantle.
来源: Lancet. 2019年393卷10173期768-777页
Generalised anxiety disorder is a disease that can be associated with substantial dysfunction. Pharmacological treatment is often the first choice for clinicians because of the cost and resource constraints of psychological alternatives, but there is a paucity of comparative information for the multiple available drug choices.
86. Carbohydrate quality and human health: a series of systematic reviews and meta-analyses.
作者: Andrew Reynolds.;Jim Mann.;John Cummings.;Nicola Winter.;Evelyn Mete.;Lisa Te Morenga.
来源: Lancet. 2019年393卷10170期434-445页
Previous systematic reviews and meta-analyses explaining the relationship between carbohydrate quality and health have usually examined a single marker and a limited number of clinical outcomes. We aimed to more precisely quantify the predictive potential of several markers, to determine which markers are most useful, and to establish an evidence base for quantitative recommendations for intakes of dietary fibre.
87. Global patterns of mortality in international migrants: a systematic review and meta-analysis.
作者: Robert W Aldridge.;Laura B Nellums.;Sean Bartlett.;Anna Louise Barr.;Parth Patel.;Rachel Burns.;Sally Hargreaves.;J Jaime Miranda.;Stephen Tollman.;Jon S Friedland.;Ibrahim Abubakar.
来源: Lancet. 2018年392卷10164期2553-2566页
258 million people reside outside their country of birth; however, to date no global systematic reviews or meta-analyses of mortality data for these international migrants have been done. We aimed to review and synthesise available mortality data on international migrants.
88. Health impacts of parental migration on left-behind children and adolescents: a systematic review and meta-analysis.
作者: Gracia Fellmeth.;Kelly Rose-Clarke.;Chenyue Zhao.;Laura K Busert.;Yunting Zheng.;Alessandro Massazza.;Hacer Sonmez.;Ben Eder.;Alice Blewitt.;Wachiraya Lertgrai.;Miriam Orcutt.;Katharina Ricci.;Olaa Mohamed-Ahmed.;Rachel Burns.;Duleeka Knipe.;Sally Hargreaves.;Therese Hesketh.;Charles Opondo.;Delan Devakumar.
来源: Lancet. 2018年392卷10164期2567-2582页
Globally, a growing number of children and adolescents are left behind when parents migrate. We investigated the effect of parental migration on the health of left behind-children and adolescents in low-income and middle-income countries (LMICs).
89. SGLT2 inhibitors for primary and secondary prevention of cardiovascular and renal outcomes in type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials.
作者: Thomas A Zelniker.;Stephen D Wiviott.;Itamar Raz.;Kyungah Im.;Erica L Goodrich.;Marc P Bonaca.;Ofri Mosenzon.;Eri T Kato.;Avivit Cahn.;Remo H M Furtado.;Deepak L Bhatt.;Lawrence A Leiter.;Darren K McGuire.;John P H Wilding.;Marc S Sabatine.
来源: Lancet. 2019年393卷10166期31-39页
The magnitude of effect of sodium-glucose cotransporter-2 inhibitors (SGLT2i) on specific cardiovascular and renal outcomes and whether heterogeneity is based on key baseline characteristics remains undefined.
90. Baseline and on-statin treatment lipoprotein(a) levels for prediction of cardiovascular events: individual patient-data meta-analysis of statin outcome trials.
作者: Peter Willeit.;Paul M Ridker.;Paul J Nestel.;John Simes.;Andrew M Tonkin.;Terje R Pedersen.;Gregory G Schwartz.;Anders G Olsson.;Helen M Colhoun.;Florian Kronenberg.;Christiane Drechsler.;Christoph Wanner.;Samia Mora.;Anastasia Lesogor.;Sotirios Tsimikas.
来源: Lancet. 2018年392卷10155期1311-1320页
Elevated lipoprotein(a) is a genetic risk factor for cardiovascular disease in general population studies. However, its contribution to risk for cardiovascular events in patients with established cardiovascular disease or on statin therapy is uncertain.
91. Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis.
作者: .;Nafees Ahmad.;Shama D Ahuja.;Onno W Akkerman.;Jan-Willem C Alffenaar.;Laura F Anderson.;Parvaneh Baghaei.;Didi Bang.;Pennan M Barry.;Mayara L Bastos.;Digamber Behera.;Andrea Benedetti.;Gregory P Bisson.;Martin J Boeree.;Maryline Bonnet.;Sarah K Brode.;James C M Brust.;Ying Cai.;Eric Caumes.;J Peter Cegielski.;Rosella Centis.;Pei-Chun Chan.;Edward D Chan.;Kwok-Chiu Chang.;Macarthur Charles.;Andra Cirule.;Margareth Pretti Dalcolmo.;Lia D'Ambrosio.;Gerard de Vries.;Keertan Dheda.;Aliasgar Esmail.;Jennifer Flood.;Gregory J Fox.;Mathilde Fréchet-Jachym.;Geisa Fregona.;Regina Gayoso.;Medea Gegia.;Maria Tarcela Gler.;Sue Gu.;Lorenzo Guglielmetti.;Timothy H Holtz.;Jennifer Hughes.;Petros Isaakidis.;Leah Jarlsberg.;Russell R Kempker.;Salmaan Keshavjee.;Faiz Ahmad Khan.;Maia Kipiani.;Serena P Koenig.;Won-Jung Koh.;Afranio Kritski.;Liga Kuksa.;Charlotte L Kvasnovsky.;Nakwon Kwak.;Zhiyi Lan.;Christoph Lange.;Rafael Laniado-Laborín.;Myungsun Lee.;Vaira Leimane.;Chi-Chiu Leung.;Eric Chung-Ching Leung.;Pei Zhi Li.;Phil Lowenthal.;Ethel L Maciel.;Suzanne M Marks.;Sundari Mase.;Lawrence Mbuagbaw.;Giovanni B Migliori.;Vladimir Milanov.;Ann C Miller.;Carole D Mitnick.;Chawangwa Modongo.;Erika Mohr.;Ignacio Monedero.;Payam Nahid.;Norbert Ndjeka.;Max R O'Donnell.;Nesri Padayatchi.;Domingo Palmero.;Jean William Pape.;Laura J Podewils.;Ian Reynolds.;Vija Riekstina.;Jérôme Robert.;Maria Rodriguez.;Barbara Seaworth.;Kwonjune J Seung.;Kathryn Schnippel.;Tae Sun Shim.;Rupak Singla.;Sarah E Smith.;Giovanni Sotgiu.;Ganzaya Sukhbaatar.;Payam Tabarsi.;Simon Tiberi.;Anete Trajman.;Lisa Trieu.;Zarir F Udwadia.;Tjip S van der Werf.;Nicolas Veziris.;Piret Viiklepp.;Stalz Charles Vilbrun.;Kathleen Walsh.;Janice Westenhouse.;Wing-Wai Yew.;Jae-Joon Yim.;Nicola M Zetola.;Matteo Zignol.;Dick Menzies.
来源: Lancet. 2018年392卷10150期821-834页
Treatment outcomes for multidrug-resistant tuberculosis remain poor. We aimed to estimate the association of treatment success and death with the use of individual drugs, and the optimal number and duration of treatment with those drugs in patients with multidrug-resistant tuberculosis.
92. Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.
Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to health accounting within the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we generated improved estimates of alcohol use and alcohol-attributable deaths and disability-adjusted life-years (DALYs) for 195 locations from 1990 to 2016, for both sexes and for 5-year age groups between the ages of 15 years and 95 years and older.
93. Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis.
作者: Derek K Chu.;Lisa H-Y Kim.;Paul J Young.;Nima Zamiri.;Saleh A Almenawer.;Roman Jaeschke.;Wojciech Szczeklik.;Holger J Schünemann.;John D Neary.;Waleed Alhazzani.
来源: Lancet. 2018年391卷10131期1693-1705页
Supplemental oxygen is often administered liberally to acutely ill adults, but the credibility of the evidence for this practice is unclear. We systematically reviewed the efficacy and safety of liberal versus conservative oxygen therapy in acutely ill adults.
94. Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis.
作者: Andrea Cipriani.;Toshi A Furukawa.;Georgia Salanti.;Anna Chaimani.;Lauren Z Atkinson.;Yusuke Ogawa.;Stefan Leucht.;Henricus G Ruhe.;Erick H Turner.;Julian P T Higgins.;Matthias Egger.;Nozomi Takeshima.;Yu Hayasaka.;Hissei Imai.;Kiyomi Shinohara.;Aran Tajika.;John P A Ioannidis.;John R Geddes.
来源: Lancet. 2018年391卷10128期1357-1366页
Major depressive disorder is one of the most common, burdensome, and costly psychiatric disorders worldwide in adults. Pharmacological and non-pharmacological treatments are available; however, because of inadequate resources, antidepressants are used more frequently than psychological interventions. Prescription of these agents should be informed by the best available evidence. Therefore, we aimed to update and expand our previous work to compare and rank antidepressants for the acute treatment of adults with unipolar major depressive disorder.
95. Atraumatic versus conventional lumbar puncture needles: a systematic review and meta-analysis.
作者: Siddharth Nath.;Alex Koziarz.;Jetan H Badhiwala.;Waleed Alhazzani.;Roman Jaeschke.;Sunjay Sharma.;Laura Banfield.;Ashkan Shoamanesh.;Sheila Singh.;Farshad Nassiri.;Wieslaw Oczkowski.;Emilie Belley-Côté.;Ray Truant.;Kesava Reddy.;Maureen O Meade.;Forough Farrokhyar.;Malgorzata M Bala.;Fayez Alshamsi.;Mette Krag.;Itziar Etxeandia-Ikobaltzeta.;Regina Kunz.;Osamu Nishida.;Charles Matouk.;Magdy Selim.;Andrew Rhodes.;Gregory Hawryluk.;Saleh A Almenawer.
来源: Lancet. 2018年391卷10126期1197-1204页
Atraumatic needles have been proposed to lower complication rates after lumbar puncture. However, several surveys indicate that clinical adoption of these needles remains poor. We did a systematic review and meta-analysis to compare patient outcomes after lumbar puncture with atraumatic needles and conventional needles.
96. Morbidity and mortality in homeless individuals, prisoners, sex workers, and individuals with substance use disorders in high-income countries: a systematic review and meta-analysis.
作者: Robert W Aldridge.;Alistair Story.;Stephen W Hwang.;Merete Nordentoft.;Serena A Luchenski.;Greg Hartwell.;Emily J Tweed.;Dan Lewer.;Srinivasa Vittal Katikireddi.;Andrew C Hayward.
来源: Lancet. 2018年391卷10117期241-250页
Inclusion health focuses on people in extremely poor health due to poverty, marginalisation, and multimorbidity. We aimed to review morbidity and mortality data on four overlapping populations who experience considerable social exclusion: homeless populations, individuals with substance use disorders, sex workers, and imprisoned individuals.
97. Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients.
作者: Angèle Gayet-Ageron.;David Prieto-Merino.;Katharine Ker.;Haleema Shakur.;François-Xavier Ageron.;Ian Roberts.; .
来源: Lancet. 2018年391卷10116期125-132页
Antifibrinolytics reduce death from bleeding in trauma and post-partum haemorrhage. We examined the effect of treatment delay on the effectiveness of antifibrinolytics.
98. Comparative efficacy and safety of reperfusion therapy with fibrinolytic agents in patients with ST-segment elevation myocardial infarction: a systematic review and network meta-analysis.
作者: Peerawat Jinatongthai.;Junporn Kongwatcharapong.;Chee Yoong Foo.;Arintaya Phrommintikul.;Surakit Nathisuwan.;Ammarin Thakkinstian.;Christopher M Reid.;Nathorn Chaiyakunapruk.
来源: Lancet. 2017年390卷10096期747-759页
Fibrinolytic therapy offers an alternative to mechanical reperfusion for ST-segment elevation myocardial infarction (STEMI) in settings where health-care resources are scarce. Comprehensive evidence comparing different agents is still unavailable. In this study, we examined the effects of various fibrinolytic drugs on clinical outcomes.
99. Optimal timing of an invasive strategy in patients with non-ST-elevation acute coronary syndrome: a meta-analysis of randomised trials.
作者: Alexander Jobs.;Shamir R Mehta.;Gilles Montalescot.;Eric Vicaut.;Arnoud W J Van't Hof.;Erik A Badings.;Franz-Josef Neumann.;Adnan Kastrati.;Alessandro Sciahbasi.;Paul-Georges Reuter.;Frédéric Lapostolle.;Aleksandra Milosevic.;Goran Stankovic.;Dejan Milasinovic.;Reinhard Vonthein.;Steffen Desch.;Holger Thiele.
来源: Lancet. 2017年390卷10096期737-746页
A routine invasive strategy is recommended for patients with non-ST-elevation acute coronary syndromes (NSTE-ACS). However, optimal timing of invasive strategy is less clearly defined. Individual clinical trials were underpowered to detect a mortality benefit; we therefore did a meta-analysis to assess the effect of timing on mortality.
100. 2-year outcomes with the Absorb bioresorbable scaffold for treatment of coronary artery disease: a systematic review and meta-analysis of seven randomised trials with an individual patient data substudy.
作者: Ziad A Ali.;Patrick W Serruys.;Takeshi Kimura.;Runlin Gao.;Stephen G Ellis.;Dean J Kereiakes.;Yoshinobu Onuma.;Charles Simonton.;Zhen Zhang.;Gregg W Stone.
来源: Lancet. 2017年390卷10096期760-772页
Bioresorbable vascular scaffolds (BVS) offer the potential to improve long-term outcomes of percutaneous coronary intervention after their complete bioresorption. Randomised trials have shown non-inferiority between BVS and metallic drug-eluting stents at 1 year in composite safety and effectiveness outcomes, although some increases in rates of target vessel-related myocardial infarction and device thrombosis were identified. Outcomes of BVS following the first year after implantation are unknown. We sought to ascertain whether BVS are as safe and effective as drug-eluting stents within 2 years after implantation and between 1 and 2 years.
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