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81. Change in FEV1 and Feno Measurements as Predictors of Future Asthma Outcomes in Children.
作者: Shona Fielding.;Marielle Pijnenburg.;Johan C de Jongste.;Katharine C Pike.;Graham Roberts.;Helen Petsky.;Anne B Chang.;Maria Fritsch.;Thomas Frischer.;Stanley Szefler.;Peter Gergen.;Francoise Vermeulen.;Robin Vael.;Steve Turner.
来源: Chest. 2019年155卷2期331-341页
Repeated measurements of spirometry and fractional exhaled nitric oxide (Feno) are recommended as part of the management of childhood asthma, but the evidence base for such recommendations is small. We tested the hypothesis that reducing spirometric indices or increasing Feno will predict poor future asthma outcomes.
82. Meta-analysis of Gastroesophageal Reflux Disease and Idiopathic Pulmonary Fibrosis.
The relationship between gastroesophageal reflux disease (GERD) and idiopathic pulmonary fibrosis (IPF) is controversial. Current guidelines recommend that clinicians use regular antacid treatment, while two recent meta-analyses of antacid therapy in IPF were inconclusive. The objective of this study was to examine the evidence regarding the association between GERD and IPF through a systematic review and a meta-analysis, with special reference to the methodologic quality of the observational studies.
83. Efficacy of Endosonographic Procedures in Mediastinal Restaging of Lung Cancer After Neoadjuvant Therapy: A Systematic Review and Diagnostic Accuracy Meta-Analysis.
作者: Valliappan Muthu.;Inderpaul S Sehgal.;Sahajal Dhooria.;Ashutosh N Aggarwal.;Ritesh Agarwal.
来源: Chest. 2018年154卷1期99-109页
The optimal modality for restaging the mediastinum following neoadjuvant therapy for lung cancer remains unclear. Surgical methods are currently considered the reference standard. The present study evaluates the role of endosonographic techniques for mediastinal restaging in lung cancer.
84. Treatment of Gastroesophageal Reflux in Patients With Idiopathic Pulmonary Fibrosis: A Systematic Review and Meta-Analysis.
Gastroesophageal reflux (GER) is common in patients with idiopathic pulmonary fibrosis (IPF) and has been proposed as a potential contributor to disease progression and exacerbation. Whether treatment of GER improves health outcomes in patients with IPF is controversial. Our objective was to review the efficacy and safety of GER treatments in IPF.
85. The Relationship Between COPD and Frailty: A Systematic Review and Meta-Analysis of Observational Studies.
作者: Alessandra Marengoni.;Davide L Vetrano.;Ester Manes-Gravina.;Roberto Bernabei.;Graziano Onder.;Katie Palmer.
来源: Chest. 2018年154卷1期21-40页
Frailty is common in seniors and is characterized by diminished physiological reserves and increased vulnerability to stressors. Frailty can change the prognosis and treatment approach of several chronic diseases, including COPD. The association between frailty and COPD has never been systematically reviewed.
86. A Systematic Review and Meta-Analysis Comparing Pigtail Catheter and Chest Tube as the Initial Treatment for Pneumothorax.
The optimal initial treatment approach for pneumothorax remains controversial. This systemic review and meta-analysis investigated the effectiveness of small-bore pigtail catheter (PC) drainage compared with that of large-bore chest tube (LBCT) drainage as the initial treatment approach for all subtypes of pneumothorax.
87. A Comparison of the Quick-SOFA and Systemic Inflammatory Response Syndrome Criteria for the Diagnosis of Sepsis and Prediction of Mortality: A Systematic Review and Meta-Analysis.
Several studies were published to validate the quick Sepsis-related Organ Failure Assessment (qSOFA), namely in comparison with the systemic inflammatory response syndrome (SIRS) criteria. We performed a systematic review and meta-analysis with the aim of comparing the qSOFA and SIRS in patients outside the ICU.
88. The Effect of Alcohol Consumption on the Risk of ARDS: A Systematic Review and Meta-Analysis.
To conduct a systematic review and meta-analysis evaluating the association between alcohol consumption and the risk of ARDS in adults.
89. Comparative Safety of Drugs Targeting the Nitric Oxide Pathway in Pulmonary Hypertension: A Mixed Approach Combining a Meta-Analysis of Clinical Trials and a Disproportionality Analysis From the World Health Organization Pharmacovigilance Database.
作者: Charles Khouri.;Marion Lepelley.;Matthieu Roustit.;François Montastruc.;Marc Humbert.;Jean-Luc Cracowski.
来源: Chest. 2018年154卷1期136-147页
Recent guidelines recommend riociguat, a soluble guanylate cyclase (sGC) stimulator, and the type 5 phosphodiesterase inhibitor (PDE5i) tadalafil or sildenafil as treatments for pulmonary arterial hypertension. We compared the safety profiles of sildenafil, tadalafil, and riociguat in pulmonary hypertension.
90. Nasal vs Oronasal CPAP for OSA Treatment: A Meta-Analysis.
作者: Rafaela G S Andrade.;Fernanda M Viana.;Juliana A Nascimento.;Luciano F Drager.;Adriano Moffa.;André R Brunoni.;Pedro R Genta.;Geraldo Lorenzi-Filho.
来源: Chest. 2018年153卷3期665-674页
Nasal CPAP is the "gold standard" treatment for OSA. However, oronasal masks are frequently used in clinical practice. The aim of this study was to perform a meta-analysis of all randomized and nonrandomized trials that compared nasal vs oronasal masks on CPAP level, residual apnea-hypopnea index (AHI), and CPAP adherence to treat OSA.
91. Trial Duration and Risk Reduction in Combination Therapy Trials for Pulmonary Arterial Hypertension: A Systematic Review.
作者: Annie C Lajoie.;Charles-Antoine Guay.;Jean-Christophe Lega.;Gabriel Lauzière.;Serge Simard.;Caroline Lambert.;Yves Lacasse.;Sebastien Bonnet.;Steeve Provencher.
来源: Chest. 2018年153卷5期1142-1152页
Relative risk (RR) and number needed-to-treat (NNT) are frequently time-dependant measures. We performed a systematic review and meta-analysis to assess whether trial duration influenced the relative and absolute risk of worsening in randomized controlled trials (RCTs) comparing combination therapy (CT) of pulmonary arterial hypertension (PAH)-specific therapies vs monotherapy (MT).
92. Impact of Rapid On-Site Cytological Evaluation (ROSE) on the Diagnostic Yield of Transbronchial Needle Aspiration During Mediastinal Lymph Node Sampling: Systematic Review and Meta-Analysis.
作者: Inderpaul Singh Sehgal.;Sahajal Dhooria.;Ashutosh Nath Aggarwal.;Ritesh Agarwal.
来源: Chest. 2018年153卷4期929-938页
Whether the use of rapid on-site cytologic evaluation (ROSE) increases the diagnostic yield of transbronchial needle aspiration (TBNA) remains unclear. This article is a systematic review of studies describing the utility of ROSE in subjects undergoing TBNA.
93. Diaphragm and Lung Ultrasound to Predict Weaning Outcome: Systematic Review and Meta-Analysis.
Deciding the optimal timing for extubation in patients who are mechanically ventilated can be challenging, and traditional weaning predictor tools are not very accurate. The aim of this systematic review and meta-analysis was to assess the accuracy of lung and diaphragm ultrasound for predicting weaning outcomes in critically ill adults.
94. Effect of Statins on COPD: A Meta-Analysis of Randomized Controlled Trials.
作者: Wen Zhang.;Yi Zhang.;Chuan-Wei Li.;Paul Jones.;Chen Wang.;Ye Fan.
来源: Chest. 2017年152卷6期1159-1168页
Much controversy persists regarding the place of statin drugs in the treatment of patients with COPD. This systematic review and meta-analysis sought to determine the clinical efficacy of statin therapy in COPD.
95. Video Laryngoscopy for Endotracheal Intubation of Critically Ill Adults: A Systemic Review and Meta-Analysis.
Endotracheal intubation (EI) in ICU patients is associated with an increased risk of life-threatening adverse events due to unstable conditions, rapid deterioration, limited preparation time, and variability in the expertise of operators. The goal of this study was to compare the effect of video laryngoscopy (VL) and direct laryngoscopy (DL) in ICU patients requiring EI.
96. Clinical Characteristics of Pertussis-Associated Cough in Adults and Children: A Diagnostic Systematic Review and Meta-Analysis.
作者: Abigail Moore.;Helen F Ashdown.;Bethany Shinkins.;Nia W Roberts.;Cameron C Grant.;Daniel S Lasserson.;Anthony Harnden.
来源: Chest. 2017年152卷2期353-367页
Pertussis (whooping cough) is a highly infective cause of cough that causes significant morbidity and mortality. Existing case definitions include paroxysmal cough, whooping, and posttussive vomiting, but diagnosis can be difficult. We determined the diagnostic accuracy of clinical characteristics of pertussis-associated cough.
97. Incidence of Pneumonitis With Use of Programmed Death 1 and Programmed Death-Ligand 1 Inhibitors in Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis of Trials.
作者: Monica Khunger.;Sagar Rakshit.;Vinay Pasupuleti.;Adrian V Hernandez.;Peter Mazzone.;James Stevenson.;Nathan A Pennell.;Vamsidhar Velcheti.
来源: Chest. 2017年152卷2期271-281页
Programmed death 1 (PD-1) programmed death-ligand 1 (PD-L1) inhibitors show significant clinical activity in non-small cell lung carcinoma (NSCLC). However, they are often associated with potentially fatal immune-mediated pneumonitis. Preliminary reports of trials suggest a difference in the rate of pneumonitis with PD-1 and PD-L1 inhibitors. We sought to determine the overall incidence of pneumonitis and differences according to type of inhibitors and prior chemotherapy use.
98. Reduced COPD Exacerbation Risk Correlates With Improved FEV1: A Meta-Regression Analysis.
作者: Alexander D Zider.;Xiaoyan Wang.;Russell G Buhr.;Worawan Sirichana.;Igor Z Barjaktarevic.;Christopher B Cooper.
来源: Chest. 2017年152卷3期494-501页
The mechanism by which various classes of medication reduce COPD exacerbation risk remains unknown. We hypothesized a correlation between reduced exacerbation risk and improvement in airway patency as measured according to FEV1.
99. The Global Burden of Atrial Fibrillation and Stroke: A Systematic Review of the Clinical Epidemiology of Atrial Fibrillation in Asia.
Our previous review reported great variability in the incidence and prevalence of atrial fibrillation (AF) in non-Western cohorts, especially from Asian countries; in recent years, epidemiologic studies on AF have been increasingly reported from Asia.
100. Prophylactic Corticosteroids for Prevention of Postextubation Stridor and Reintubation in Adults: A Systematic Review and Meta-analysis.
Corticosteroid administration before elective extubation has been used to prevent postextubation stridor and reintubation. We updated a systematic review to identify which patients would benefit from prophylactic corticosteroid administration before elective extubation.
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