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861. Comparison of the peak exercise response measured by the ramp and 1-min step cycle exercise protocols in patients with exertional dyspnea.
To compare the peak exercise response and determine the limits of agreement between the ramp and the 1-min step cycle protocols in a representative population of patients with exertional breathlessness attending a respiratory outpatient clinic.
862. Power of outcome measurements to detect clinically significant changes in pulmonary rehabilitation of patients with COPD.
作者: Juan Pablo de Torres.;Victor Pinto-Plata.;Edward Ingenito.;Peter Bagley.;Anthony Gray.;Robert Berger.;Bartolome Celli.
来源: Chest. 2002年121卷4期1092-8页
Several validated instruments are used to measure outcomes, such as exercise performance, dyspnea, and health-related quality of life after pulmonary rehabilitation (PR) in patients with COPD. However, no study has simultaneously compared the responsiveness of the most frequently used outcome measurements after PR. We designed this study to investigate the capacity of several of the most frequently used outcome measurements to detect changes after PR in a population of patients with severe COPD who qualified for lung volume reduction surgery.
863. An evaluation of two approaches to exercise conditioning in pulmonary rehabilitation.
作者: Edgar A Normandin.;Corliss McCusker.;MaryLou Connors.;Frederick Vale.;Daniel Gerardi.;Richard L ZuWallack.
来源: Chest. 2002年121卷4期1085-91页
To compare the effectiveness of two forms of exercise training in pulmonary rehabilitation.
864. Megestrol acetate stimulates weight gain and ventilation in underweight COPD patients.
作者: Jeffrey Weisberg.;Jack Wanger.;Jeffery Olson.;Barry Streit.;Charles Fogarty.;Thomas Martin.;Richard Casaburi.
来源: Chest. 2002年121卷4期1070-8页
To assess the effect of megestrol acetate (MA), a progestational appetite stimulant commonly used in patients with AIDS and cancer, on body weight and composition, respiratory muscle strength, arterial blood gas levels, and subjective perceptions in COPD patients.
865. Comparison of the efficacy, tolerability, and safety of formoterol dry powder and oral, slow-release theophylline in the treatment of COPD.
作者: Andrea Rossi.;Peter Kristufek.;Bernard E Levine.;Moira H Thomson.;Denise Till.;John Kottakis.;Giovanni Della Cioppa.; .
来源: Chest. 2002年121卷4期1058-69页
To compare the efficacy, tolerability, and safety of therapy with formoterol and oral slow-release theophylline (THEO) in patients with COPD.
866. A randomized clinical trial of intermittent subglottic secretion drainage in patients receiving mechanical ventilation.
作者: Kees Smulders.;Hans van der Hoeven.;Ineke Weers-Pothoff.;Christina Vandenbroucke-Grauls.
来源: Chest. 2002年121卷3期858-62页
To study the effect of subglottic secretions drainage on the incidence of ventilator-associated pneumonia (VAP) in patients receiving mechanical ventilation.
867. Suction vs water seal after pulmonary resection: a randomized prospective study.
作者: M Blair Marshall.;Maher E Deeb.;Joshua I S Bleier.;John C Kucharczuk.;Joseph S Friedberg.;Larry R Kaiser.;Joseph B Shrager.
来源: Chest. 2002年121卷3期831-5页
To evaluate whether suction or water seal is superior in the management of chest tubes after pulmonary resection.
868. Home unattended vs hospital telemonitored polysomnography in suspected obstructive sleep apnea syndrome: a randomized crossover trial.
作者: Frédéric Gagnadoux.;Nathalie Pelletier-Fleury.;Carole Philippe.;Dominique Rakotonanahary.;Bernard Fleury.
来源: Chest. 2002年121卷3期753-8页
To compare home unattended polysomnography (H-PSG) with polysomnography performed in a local hospital and telemonitored by a sleep laboratory (T-PSG) in the diagnosis of obstructive sleep apnea syndrome (OSAS).
869. 4-year follow-up of treatment with dental appliance or uvulopalatopharyngoplasty in patients with obstructive sleep apnea: a randomized study.
作者: Marie-Louise Walker-Engström.;Ake Tegelberg.;Bo Wilhelmsson.;Ivar Ringqvist.
来源: Chest. 2002年121卷3期739-46页
To evaluate the effects of treatment with a dental appliance or uvulopalatopharyngoplasty (UPPP) on somnographic variables in patients with mild-to-moderate obstructive sleep apnea (OSA) followed up for 4 years, and compliance and complementary treatment.
870. Reduction of eosinophilic inflammation in the airways of patients with asthma using montelukast.
作者: Kenji Minoguchi.;Yasurou Kohno.;Hideko Minoguchi.;Norio Kihara.;Yasuyuki Sano.;Hajime Yasuhara.;Mitsuru Adachi.
来源: Chest. 2002年121卷3期732-8页
Leukotrienes (LTs) are involved in airway eosinophilic inflammation in patients with asthma. We examined the effects of a cysteinyl LT 1-receptor antagonist, montelukast, on sputum eosinophil levels, and the correlation between sputum eosinophils and bronchodilatation in patients with asthma.
871. Use of a mucus clearance device enhances the bronchodilator response in patients with stable COPD.
To determine whether the use of a mucus clearance device (MCD) [Flutter; Axcan Scandipharm; Birmingham, AL] could improve the bronchodilator response to inhaled ipratropium and salbutamol delivered by a metered-dose inhaler in patients with stable, severe COPD.
872. Effect of continuous positive airway pressure on the rapid shallow breathing index in patients following cardiac surgery.
作者: Mohamad F El-Khatib.;Ghassan W Jamaleddine.;Andre R Khoury.;Mounir Y Obeid.
来源: Chest. 2002年121卷2期475-9页
To compare the rapid shallow breathing index (RSBI) under different ventilatory support settings prior to extubation trials.
873. Effect of hyperoxia on gas exchange and lactate kinetics following exercise onset in nonhypoxemic COPD patients.
The slow oxygen uptake (VO(2)) kinetics observed in COPD patients is a manifestation of skeletal muscle dysfunction of multifactorial origin. We determined whether oxygen supplementation during exercise makes the dynamic VO(2) response faster and reduces transient lactate increase.
874. Discontinuation of furosemide decreases PaCO(2) in patients with COPD.
作者: Folkert Brijker.;Yvonne F Heijdra.;Frank J J van den Elshout.;Hans Th M Folgering.
来源: Chest. 2002年121卷2期377-82页
To evaluate whether the discontinuation of furosemide treatment resulted in a decrease in PaCO(2) and an increase in daytime and nocturnal oxygenation.
875. Initial improvements in lung function and bronchial hyperresponsiveness are maintained during 5 years of treatment with inhaled beclomethasone dipropionate and terbutaline.
作者: W Rob Douma.;Huib A M Kerstjens.;Ad de Gooijer.;Shelley E Overbeek.;Gerard H Koëter.;Dirkje S Postma.; .
来源: Chest. 2002年121卷1期151-7页
Treatment with inhaled corticosteroids reduces bronchial hyperresponsiveness and relieves airways obstruction in patients with asthma. Up to now, it is unknown whether initial improvements are maintained over a long period of time. Therefore, we assessed whether initial improvements in FEV(1), provocative concentration of histamine causing a 20% fall in FEV(1) (PC(20)), and peak expiratory flow (PEF) persist with a constant dose of inhaled corticosteroids. Furthermore, we investigated whether FEV(1), PC(20), PEF indexes, and symptom scores improve after increasing the dose of inhaled corticosteroids in patients who did not respond sufficiently to treatment with beclomethasone dipropionate (BDP), 800 microg/d.
876. Long-term benefits of inhaled tobramycin in adolescent patients with cystic fibrosis.
To determine the effect of long-term suppression of Pseudomonas aeruginosa on lung function and other clinical end points in adolescent patients with cystic fibrosis (CF).
877. Early treatment of stage II sarcoidosis improves 5-year pulmonary function.
作者: Anne Pietinalho.;Pentti Tukiainen.;Tari Haahtela.;Tore Persson.;Olof Selroos.; .
来源: Chest. 2002年121卷1期24-31页
To evaluate the 5-year prognosis of patients with stage I and stage II newly detected (< 3 months) pulmonary sarcoidosis treated immediately after diagnosis with prednisolone for 3 months followed by inhaled budesonide for 15 months.
878. Atrial mechanical performance after internal and external cardioversion of atrial fibrillation: an echocardiographic study.
作者: Günter Lehmann.;Jörg Horcher.;Karl Dennig.;Andreas Plewan.;Kurt Ulm.;Eckhard Alt.
来源: Chest. 2002年121卷1期13-8页
To compare the time course of resumption of mechanical performance of the left and right atrium after the novel method of internal low-energy cardioversion (CV) and conventional external CV of atrial fibrillation (AF).
879. Cost-effectiveness of fluticasone propionate administered via metered-dose inhaler plus babyhaler spacer in the treatment of asthma in preschool-aged children.
To evaluate the cost-effectiveness of inhaled fluticasone propionate (FP) in children aged 12 to 47 months with asthma symptoms.
880. Inhaled beclomethasone dipropionate improves acoustic measures of voice in patients with asthma.
Inhaled corticosteroids have the potential to produce upper-airway side effects such as hoarseness. As new compounds and delivery devices are developed and compared, it is difficult to quantify their adverse upper-airway effects.
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