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821. Cost-effectiveness of IV-to-oral switch therapy: azithromycin vs cefuroxime with or without erythromycin for the treatment of community-acquired pneumonia.
作者: Joseph A Paladino.;Larry D Gudgel.;Alan Forrest.;Michael S Niederman.
来源: Chest. 2002年122卷4期1271-9页
To conduct a cost-effectiveness analysis of IV-to-oral regimens of azithromycin vs cefuroxime with or without erythromycin in the treatment of patients hospitalized with community-acquired pneumonia (CAP).
822. Comparison of high-dose inhaled flunisolide to systemic corticosteroids in severe adult asthma.
作者: Mary Lee-Wong.;Francis M Dayrit.;Anita R Kohli.;Samuel Acquah.;Paul H Mayo.
来源: Chest. 2002年122卷4期1208-13页
To investigate whether, after 48 h of IV treatment with corticosteroids, the use of high-dose inhaled flunisolide is as effective as systemic corticosteroids in adults hospitalized for a severe asthma exacerbation.
823. Effects of a telephone-based psychosocial intervention for patients awaiting lung transplantation.
作者: Melissa A Napolitano.;Michael A Babyak.;Scott Palmer.;Victor Tapson.;R Duane Davis.;James A Blumenthal.; .
来源: Chest. 2002年122卷4期1176-84页
To test the efficacy of a tailored telephone-based intervention consisting of supportive counseling and cognitive behavioral techniques for individuals awaiting lung transplantation on measures of quality of life and general well-being.
824. Home sleep studies in the assessment of sleep apnea/hypopnea syndrome.
To determine the clinical utility of a limited sleep-recording device used unsupervised in the patient's home, compared with in-laboratory, fully supervised polysomnography for the diagnosis of sleep apnea/hypopnea syndrome (SAHS), and to assess its impact on costs.
825. Comparison of sputum induction using high-output and low-output ultrasonic nebulizers in normal subjects and patients with COPD.
作者: Martin G Kelly.;Vanessa Brown.;S Lorraine Martin.;Madeleine Ennis.;J Stuart Elborn.
来源: Chest. 2002年122卷3期955-9页
s: Induced sputum is used to investigate pulmonary diseases. Low-output ultrasonic nebulizers have become available and have potential advantages over high-output nebulizers. We hypothesized that a low-output nebulizer would give comparable results to a high-output nebulizer, with an acceptable safety profile.
826. Exercise maintenance following pulmonary rehabilitation: effect of distractive stimuli.
作者: Gerene S Bauldoff.;Leslie A Hoffman.;Thomas G Zullo.;Frank C Sciurba.
来源: Chest. 2002年122卷3期948-54页
To determine if distractive auditory stimuli (DAS) in the form of music would promote adherence to a walking regimen following completion of a pulmonary rehabilitation program (PRP) and, thereby, maintenance of gains achieved during the program.
827. Early ribavarin treatment of bronchiolitis: effect on long-term respiratory morbidity.
The mortality rate from respiratory syncytial virus (RSV) bronchiolitis has significantly reduced over the last decade. A major concern now is the long-term respiratory morbidity following RSV bronchiolitis.
828. Evaluation of bronchial constriction in children with cystic fibrosis after inhaling two different preparations of tobramycin.
作者: Ghassan A Alothman.;Muslim M Alsaadi.;Bernard L Ho.;Sharon L Ho.;Annie Dupuis.;Mary Corey.;Allan L Coates.
来源: Chest. 2002年122卷3期930-4页
This randomized, double-blind, cross-over study evaluated the risk of bronchoconstriction with two preparations of inhaled tobramycin in children with cystic fibrosis (CF) infected with Pseudomonas aeruginosa with and without airway hyperreactivity.
829. The community-acquired pneumonia symptom questionnaire: a new, patient-based outcome measure to evaluate symptoms in patients with community-acquired pneumonia.
作者: Donna L Lamping.;Sara Schroter.;Patrick Marquis.;Alexia Marrel.;Isabelle Duprat-Lomon.;Pierre-Philippe Sagnier.
来源: Chest. 2002年122卷3期920-9页
s: To develop and validate a patient-based outcome measure to evaluate symptoms in patients with community-acquired pneumonia (CAP).
830. Fluticasone propionate via the Diskhaler or hydrofluoroalkane-134a metered-dose inhaler on methacholine-induced airway hyperresponsiveness.
作者: Stephen J Langley.;Janet Holden.;Alison Derham.;Paul Hedgeland.;Raj K Sharma.;Ashley Woodcock.
来源: Chest. 2002年122卷3期806-11页
s: To compare the effect of 4 weeks of treatment with fluticasone propionate (FP), 100 micro g bid, delivered either via the Diskhaler (GlaxoSmithKline; Middlesex, UK) or a hydrofluoroalkane (HFA)-134a pressurized metered-dose inhaler (pMDI) on airway responsiveness.
831. Effect of salmeterol on seasonal changes in airway responsiveness and exhaled nitric oxide in pollen-sensitive asthmatic subjects.
作者: Luis Prieto.;Valentina Gutiérrez.;Vicente Torres.;Sonia Uixera.;Julio Marín.
来源: Chest. 2002年122卷3期798-805页
Using a model of natural allergen exposure, we examined the effect of regular treatment with salmeterol on allergen-induced changes in airway responsiveness and exhaled nitric oxide (ENO).
832. Adverse behavioral effects of treatment for acute exacerbation of asthma in children: a comparison of two doses of oral steroids.
To determine the relative adverse symptomatic effects and benefits of therapy with oral corticosteroids at doses of 2 mg/kg vs 1 mg/kg daily in children with acute exacerbations of asthma.
833. Therapeutic ratio of hydrofluoroalkane and chlorofluorocarbon formulations of fluticasone propionate.
作者: Stephen J Fowler.;Linda C Orr.;Erika J Sims.;Andrew M Wilson.;Graeme P Currie.;Lesley McFarlane.;Brian J Lipworth.
来源: Chest. 2002年122卷2期618-23页
To compare the therapeutic ratio of chlorofluorocarbon (CFC) and hydrofluoroalkane-134a (HFA) formulations of fluticasone propionate (FP).
834. An individually adjustable oral appliance vs continuous positive airway pressure in mild-to-moderate obstructive sleep apnea syndrome.
For the treatment of nonsevere obstructive sleep apnea syndrome (OSAS), mandibular advancement devices (MADs) are employed as an alternative to nasal continuous positive airway pressure (CPAP) therapy. However, very few specific data on the effectiveness of MADs in this group of patients are available. We therefore compared an individually adjustable intraoral sleep apnea device (ISAD) that permits movements of the lower jaw in three dimensions, with CPAP in the treatment of patients with an apnea/hypopnea index (AHI) < or = 30/h.
835. Teaching time for metered-dose inhalers in the emergency setting.
作者: Yuka Numata.;Jean Bourbeau.;Pierre Ernst.;Guylaine Duquette.;Kevin Schwartzman.
来源: Chest. 2002年122卷2期498-504页
In some acute-care settings, practitioners are reluctant to institute bronchodilator therapy with metered-dose inhalers (MDIs) as standard management. Such therapy requires that personnel ensure optimal use of these devices. We prospectively evaluated the time required to teach patients correct inhaler use for the emergency treatment of asthma and COPD, and patient factors associated with duration of teaching.
836. IV magnesium sulfate in the treatment of acute severe asthma: a multicenter randomized controlled trial.
作者: Robert A Silverman.;Harold Osborn.;Jeffrey Runge.;E John Gallagher.;William Chiang.;James Feldman.;Theodore Gaeta.;Katherine Freeman.;Bruce Levin.;Noel Mancherje.;Steven Scharf.; .
来源: Chest. 2002年122卷2期489-97页
Studies of IV magnesium sulfate as a treatment for acute asthma have had mixed results, with some data suggesting a benefit for acute severe asthma, but not for mild-to-moderate asthma. In a multicenter cohort, this study tests the hypothesis that administration of magnesium sulfate improves pulmonary function in patients with acute severe asthma.
837. Mask proportional assist vs pressure support ventilation in patients in clinically stable condition with chronic ventilatory failure.
作者: Roberto Porta.;Lorenzo Appendini.;Michele Vitacca.;Luca Bianchi.;Claudio F Donner.;Roberta Poggi.;Nicolino Ambrosino.
来源: Chest. 2002年122卷2期479-88页
To compare the short-term physiologic effects of mask pressure support ventilation (PSV) and proportional assist ventilation (PAV) in patients in clinically stable condition with chronic ventilatory failure (CVF).
838. Effects of training with heliox and noninvasive positive pressure ventilation on exercise ability in patients with severe COPD.
We sought to determine whether breathing heliox or using nasal noninvasive positive pressure ventilation (NIPPV) would produce immediate improvements in exercise capability in patients with COPD, and whether training for 6 weeks with one of these modalities would result in greater exercise improvement than with training unassisted.
839. Refillable oxygen cylinders may be an alternative for ambulatory oxygen therapy in COPD.
作者: Antoine Cuvelier.;Jean-François Nuir.;Nadia Chakroun.;Jérôme Aboab.;Gabriella Onea.;Daniel Benhamou.
来源: Chest. 2002年122卷2期451-6页
To compare, in clinical conditions, the efficacy of refilled oxygen cylinders (O2-HFs) in improving oxygenation and exercise capacity of patients with COPD during a 6-min walking test.
840. Cerebral oxygenation during exercise in patients with terminal lung disease.
作者: Gabrielle Jensen.;Henning Bay Nielsen.;Kojiro Ide.;Per Lav Madsen.;Lars Bo Svendsen.;Ulrik Gerner Svendsen.;Niels Henry Secher.
来源: Chest. 2002年122卷2期445-50页
In patients with terminal lung disease who were exercising, we assessed whether improved arterial O2 saturation with an increased fraction of inspired oxygen (FIO2) affects cerebral oxygenation.
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