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61. Validation of a Serum-Based Biomarker Signature for Detection of Early-Stage Pancreatic Ductal Adenocarcinoma.
作者: Aimee L Lucas.;Diane M Simeone.;Bryson W Katona.;Salvatore Paiella.;George Zogopoulos.;Rosalie C Sears.;Eli M Grindedal.;Raymond C Wadlow.;Erkut Borazanci.;Ora K Gordon.;Fay Kastrinos.;Jose G Trevino.;Sonia S Kupfer.;Walter G Park.;Jessica N Everett.;Natasha M Kureshi.;George DeMuth.;Lisa Ford.;Thomas King.;Norma A Palma.;Randall E Brand.
来源: Gastroenterology. 2025年
This study's goal was to clinically validate the performance of PancreaSure (Immunovia, Inc), a serum biomarker signature composed of tissue inhibitor of metalloproteinase 1, intercellular adhesion molecule 1, cathepsin D, thrombospondin 1, and carbohydrate antigen 19-9 for detection of early-stage pancreatic ductal adenocarcinoma (PDAC) in an independent cohort.
62. Health education based on precede-proceed model in eradication evaluation of Helicobacter pylori infection: a retrospective cohort study.
作者: Huihui Shang.;Xinya Zhang.;Yan Li.;Li Gui.;Yu Wang.;Song Xu.;Kaifu Zheng.
来源: BMC Gastroenterol. 2025年25卷1期762页
To investigate the influence of health education based on the precede-proceed model (PPM) on the eradication rate and experience of Helicobacter pylori (H. pylori) infection.
63. Efficacy of TDF, TAF, TMF, and TDF-to-TAF switch in chronic hepatitis B: a network meta-analysis.
作者: Shuqi Yang.;Yijie Lin.;Huatang Zhang.;Yanlan Liang.;Wenjin Yuan.;Xing Wang.;Wenwu Lin.;Wencong Hong.;Zhijun Su.;Dawu Zeng.;Xueping Yu.
来源: BMC Gastroenterol. 2025年25卷1期760页
We compared the efficacy of four treatment strategies for chronic hepatitis B (CHB): tenofovir disoproxil fumarate (TDF), tenofovir alafenamide (TAF), tenofovir amibufenamide (TMF), and TDF-to-TAF switch strategies strategy. We conducted a network meta-analysis to provide evidence-based clinical guidance.
64. The association between serum HbA1c and infected pancreatic necrosis in acute necrotizing pancreatitis.
作者: Xinyu Wang.;Yiwei Luo.;Gang Li.;Dadong Liu.;Jingzhu Zhang.;Jing Zhou.;Bo Ye.;Wenjian Mao.;Lu Ke.;Yuxiu Liu.;Weiqin Li.;Zhihui Tong.
来源: BMC Gastroenterol. 2025年25卷1期763页
Given the evidence that poor glycemic control is associated with immunological dysfunction, serum glycosylated hemoglobin A1c (HbA1c), as a useful indicator reflecting blood glucose homeostasis, has potential to predict infectious complications. In this study, we aimed to explore the association between poor glycemic control (HbA1c ≥ 6.5 as an indicator) and infected pancreatic necrosis (IPN) in patients with acute necrotizing pancreatitis (ANP).
65. Elevated serum ferritin as a predictor of complications in cirrhotic patients: a retrospective cohort study.
作者: Maissae Rahaoui.;Amri Fakhrddine.;Ouiam Elmqaddem.;Hajar Koulali.;Abdelkrim Zazour.;Zahi Ismaili.;Ghizlane Kharrasse.
来源: BMC Gastroenterol. 2025年25卷1期761页
Cirrhosis is a major cause of morbidity and mortality worldwide [1]. While serum ferritin is recognized as a marker of liver injury and inflammation, its prognostic value for cirrhosis-related complications is not well established. We investigated whether serum ferritin levels could predict complications in cirrhotic patients.
66. Health cooking at home: can cooking skills reduce gastrointestinal symptoms, cross sectional study?
The acquisition of healthy nutrition habits plays an important role in the solution of gastrointestinal symptoms, and it was recently shown that the cooking skills were the main determinant in the development of these behaviors. Accordingly, this study was planned and conducted with an aim to investigate the relationship between gastrointestinal symptoms and cooking skills.
67. Gastro-oesophageal reflux disease symptom subtypes and endoscopy findings: a retrospective, cross-sectional study from Southwestern Nigeria.
作者: E Odeghe.;A Itam-Eyo.;A Oluyemi.;O Owoseni.;A Nnadi.;J Uchechukwu.;O Onodingene.;S Tamunodukobipi.;O Adeniyi.;M Lawal.;G Oyeleke.
来源: BMC Gastroenterol. 2025年25卷1期758页
Gastro-oesophageal reflux disease (GORD) presents with either oesophageal or extra-oesophageal symptoms, or both. The association between symptom subtypes and upper gastrointestinal endoscopy (UGIE) findings has been rarely studied in Nigeria. Our study aimed to determine the pattern of symptom subtypes and UGIE abnormalities, as well as their association in patients with GORD symptoms in Nigeria.
68. Prognostic importance of CD47 expression on survival of colorectal cancer.
作者: Oktay Halit Aktepe.;Olcay Kurtulan.;Pinar Ezgi Dama.;Eda Caliskan Yildirim.;Aytac Terzi.;Simin Alara Kalyoncu.;Elif Atag.;Tugba Yavuzsen.;Meral Uner.;Aziz Karaoglu.;Suayib Yalcin.
来源: BMC Gastroenterol. 2025年25卷1期757页
The exact value of cluster of differentiation 47 (CD47), known as the "don't eat me" signal, in colorectal cancer (CRC) has not been clearly revealed. Thus, we investigated the impact of its expression on the overall survival (OS) of CRC patients who underwent colectomy.
71. Enhancing explainability of random survival forests in predicting stent patency risk for malignant colonic obstruction.
作者: Yuan Wan.;Meng-Sha Zou.;Dan Li.;Ying Li.;Xiao-Zheng Cao.;Bo Zhang.;Huan-Hua Wu.
来源: BMC Gastroenterol. 2025年25卷1期754页
This study aims to enhance the explainability and predictive accuracy of the Random Survival Forest (RSF) algorithm in predicting stent patency risk for patients with malignant colonic obstruction.
72. Artificial intelligence-assisted colonoscopy improves adenoma detection rates in routine colonoscopy practice: a single-center, retrospective, propensity score-matched study with concurrent controls.
作者: Da Yeon Ham.;Jae Gon Lee.;Chung Il Ahn.;Sea Hyub Kae.;Hyun Joo Jang.
来源: BMC Gastroenterol. 2025年25卷1期755页
This study aimed to investigate whether a real-time artificial intelligence (AI)-assisted polyp detection system can improve adenoma detection rates (ADRs) in real-world colonoscopy practice.
73. Association of gastroesophageal reflux disease with small intestinal bacterial overgrowth: a case-control study.
作者: Zhiwei Hu.;Baodong Shan.;Yizhou Wang.;Jun Yang.;Lili Lu.;Yanhong Wang.;Xunlei Pang.
来源: BMC Gastroenterol. 2025年25卷1期753页
To explore the potential correlation between alterations in gut microbiota and gastroesophageal reflux disease (GERD) among patients.
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