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61. Oral immunotherapy for peanut allergy (PACE): a systematic review and meta-analysis of efficacy and safety.
作者: Derek K Chu.;Robert A Wood.;Shannon French.;Alessandro Fiocchi.;Manel Jordana.;Susan Waserman.;Jan L Brożek.;Holger J Schünemann.
来源: Lancet. 2019年393卷10187期2222-2232页
Oral immunotherapy is an emerging experimental treatment for peanut allergy, but its benefits and harms are unclear. We systematically reviewed the efficacy and safety of oral immunotherapy versus allergen avoidance or placebo (no oral immunotherapy) for peanut allergy.
62. Clinical outcomes after ABO-incompatible renal transplantation: a systematic review and meta-analysis.
作者: Florian G Scurt.;Lara Ewert.;Peter R Mertens.;Hermann Haller.;Bernhard M W Schmidt.;Christos Chatzikyrkou.
来源: Lancet. 2019年393卷10185期2059-2072页
ABO-incompatible renal transplantation (ABOi-rTx) is increasingly used to overcome organ shortage. Evidence about its non-inferiority in comparison with ABO-compatible renal transplantation (ABOc-rTx) needs to be analysed at early and late timepoints. We aimed to investigate differences in outcome after ABOi-rTX and ABOc-rTX.
63. Maternal and perinatal mortality and complications associated with caesarean section in low-income and middle-income countries: a systematic review and meta-analysis.
作者: Soha Sobhy.;David Arroyo-Manzano.;Nilaani Murugesu.;Gayathri Karthikeyan.;Vinoth Kumar.;Inderjeet Kaur.;Evita Fernandez.;Sirisha Rao Gundabattula.;Ana Pilar Betran.;Khalid Khan.;Javier Zamora.;Shakila Thangaratinam.
来源: Lancet. 2019年393卷10184期1973-1982页
Universal and timely access to a caesarean section is a key requirement for safe childbirth. We identified the burden of maternal and perinatal mortality and morbidity, and the risk factors following caesarean sections in low-income and middle-income countries (LMICs).
64. How long does a knee replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow-up.
作者: Jonathan T Evans.;Robert W Walker.;Jonathan P Evans.;Ashley W Blom.;Adrian Sayers.;Michael R Whitehouse.
来源: Lancet. 2019年393卷10172期655-663页
Knee replacements are the mainstay of treatment for end-stage osteoarthritis and are effective. Given time, all knee replacements will fail and knowing when this failure might happen is important. We aimed to establish how long a knee replacement lasts.
65. How long does a hip replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow-up.
作者: Jonathan T Evans.;Jonathan P Evans.;Robert W Walker.;Ashley W Blom.;Michael R Whitehouse.;Adrian Sayers.
来源: Lancet. 2019年393卷10172期647-654页
Total hip replacement is a common and highly effective operation. All hip replacements would eventually fail if in situ long enough and it is important that patients understand when this might happen. We aimed to answer the question: how long does a hip replacement last?
66. Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses.
作者: Caroline Ovadia.;Paul T Seed.;Alexandros Sklavounos.;Victoria Geenes.;Chiara Di Ilio.;Jenny Chambers.;Katherine Kohari.;Yannick Bacq.;Nuray Bozkurt.;Romana Brun-Furrer.;Laura Bull.;Maria C Estiú.;Monika Grymowicz.;Berrin Gunaydin.;William M Hague.;Christian Haslinger.;Yayi Hu.;Tetsuya Kawakita.;Ayse G Kebapcilar.;Levent Kebapcilar.;Jūratė Kondrackienė.;Maria P H Koster.;Aneta Kowalska-Kańka.;Limas Kupčinskas.;Richard H Lee.;Anna Locatelli.;Rocio I R Macias.;Hanns-Ulrich Marschall.;Martijn A Oudijk.;Yael Raz.;Eli Rimon.;Dan Shan.;Yong Shao.;Rachel Tribe.;Valeria Tripodi.;Cigdem Yayla Abide.;Ilter Yenidede.;Jim G Thornton.;Lucy C Chappell.;Catherine Williamson.
来源: Lancet. 2019年393卷10174期899-909页
Intrahepatic cholestasis of pregnancy is associated with adverse perinatal outcomes, but the association with the concentration of specific biochemical markers is unclear. We aimed to quantify the adverse perinatal effects of intrahepatic cholestasis of pregnancy in women with increased serum bile acid concentrations and determine whether elevated bile acid concentrations were associated with the risk of stillbirth and preterm birth.
67. Pharmacological treatments for generalised anxiety disorder: a systematic review and network meta-analysis.
作者: April Slee.;Irwin Nazareth.;Paulina Bondaronek.;Yifeng Liu.;Zhihang Cheng.;Nick Freemantle.
来源: Lancet. 2019年393卷10173期768-777页
Generalised anxiety disorder is a disease that can be associated with substantial dysfunction. Pharmacological treatment is often the first choice for clinicians because of the cost and resource constraints of psychological alternatives, but there is a paucity of comparative information for the multiple available drug choices.
68. Carbohydrate quality and human health: a series of systematic reviews and meta-analyses.
作者: Andrew Reynolds.;Jim Mann.;John Cummings.;Nicola Winter.;Evelyn Mete.;Lisa Te Morenga.
来源: Lancet. 2019年393卷10170期434-445页
Previous systematic reviews and meta-analyses explaining the relationship between carbohydrate quality and health have usually examined a single marker and a limited number of clinical outcomes. We aimed to more precisely quantify the predictive potential of several markers, to determine which markers are most useful, and to establish an evidence base for quantitative recommendations for intakes of dietary fibre.
69. Global patterns of mortality in international migrants: a systematic review and meta-analysis.
作者: Robert W Aldridge.;Laura B Nellums.;Sean Bartlett.;Anna Louise Barr.;Parth Patel.;Rachel Burns.;Sally Hargreaves.;J Jaime Miranda.;Stephen Tollman.;Jon S Friedland.;Ibrahim Abubakar.
来源: Lancet. 2018年392卷10164期2553-2566页
258 million people reside outside their country of birth; however, to date no global systematic reviews or meta-analyses of mortality data for these international migrants have been done. We aimed to review and synthesise available mortality data on international migrants.
70. Health impacts of parental migration on left-behind children and adolescents: a systematic review and meta-analysis.
作者: Gracia Fellmeth.;Kelly Rose-Clarke.;Chenyue Zhao.;Laura K Busert.;Yunting Zheng.;Alessandro Massazza.;Hacer Sonmez.;Ben Eder.;Alice Blewitt.;Wachiraya Lertgrai.;Miriam Orcutt.;Katharina Ricci.;Olaa Mohamed-Ahmed.;Rachel Burns.;Duleeka Knipe.;Sally Hargreaves.;Therese Hesketh.;Charles Opondo.;Delan Devakumar.
来源: Lancet. 2018年392卷10164期2567-2582页
Globally, a growing number of children and adolescents are left behind when parents migrate. We investigated the effect of parental migration on the health of left behind-children and adolescents in low-income and middle-income countries (LMICs).
71. SGLT2 inhibitors for primary and secondary prevention of cardiovascular and renal outcomes in type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials.
作者: Thomas A Zelniker.;Stephen D Wiviott.;Itamar Raz.;Kyungah Im.;Erica L Goodrich.;Marc P Bonaca.;Ofri Mosenzon.;Eri T Kato.;Avivit Cahn.;Remo H M Furtado.;Deepak L Bhatt.;Lawrence A Leiter.;Darren K McGuire.;John P H Wilding.;Marc S Sabatine.
来源: Lancet. 2019年393卷10166期31-39页
The magnitude of effect of sodium-glucose cotransporter-2 inhibitors (SGLT2i) on specific cardiovascular and renal outcomes and whether heterogeneity is based on key baseline characteristics remains undefined.
72. Mortality due to low-quality health systems in the universal health coverage era: a systematic analysis of amenable deaths in 137 countries.
作者: Margaret E Kruk.;Anna D Gage.;Naima T Joseph.;Goodarz Danaei.;Sebastián García-Saisó.;Joshua A Salomon.
来源: Lancet. 2018年392卷10160期2203-2212页
Universal health coverage has been proposed as a strategy to improve health in low-income and middle-income countries (LMICs). However, this is contingent on the provision of good-quality health care. We estimate the excess mortality for conditions targeted in the Sustainable Development Goals (SDG) that are amenable to health care and the portion of this excess mortality due to poor-quality care in 137 LMICs, in which excess mortality refers to deaths that could have been averted in settings with strong health systems.
73. Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis.
作者: Derek K Chu.;Lisa H-Y Kim.;Paul J Young.;Nima Zamiri.;Saleh A Almenawer.;Roman Jaeschke.;Wojciech Szczeklik.;Holger J Schünemann.;John D Neary.;Waleed Alhazzani.
来源: Lancet. 2018年391卷10131期1693-1705页
Supplemental oxygen is often administered liberally to acutely ill adults, but the credibility of the evidence for this practice is unclear. We systematically reviewed the efficacy and safety of liberal versus conservative oxygen therapy in acutely ill adults.
74. The relation between health research output and burden of disease in Palestine: a systematic review.
Highest priority should be given to research on conditions responsible for the greatest disease burden. This is particularly important in settings where resources are scarce. The aim of this study was to assess the association between research output and disease burden in the occupied Palestinian territory and to identify the conditions that are under-investigated or over-investigated, if any.
75. Mortality after coronary artery bypass grafting versus percutaneous coronary intervention with stenting for coronary artery disease: a pooled analysis of individual patient data.
作者: Stuart J Head.;Milan Milojevic.;Joost Daemen.;Jung-Min Ahn.;Eric Boersma.;Evald H Christiansen.;Michael J Domanski.;Michael E Farkouh.;Marcus Flather.;Valentin Fuster.;Mark A Hlatky.;Niels R Holm.;Whady A Hueb.;Masoor Kamalesh.;Young-Hak Kim.;Timo Mäkikallio.;Friedrich W Mohr.;Grigorios Papageorgiou.;Seung-Jung Park.;Alfredo E Rodriguez.;Joseph F Sabik.;Rodney H Stables.;Gregg W Stone.;Patrick W Serruys.;Arie Pieter Kappetein.
来源: Lancet. 2018年391卷10124期939-948页
Numerous randomised trials have compared coronary artery bypass grafting (CABG) with percutaneous coronary intervention (PCI) for patients with coronary artery disease. However, no studies have been powered to detect a difference in mortality between the revascularisation strategies.
76. Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis.
作者: Andrea Cipriani.;Toshi A Furukawa.;Georgia Salanti.;Anna Chaimani.;Lauren Z Atkinson.;Yusuke Ogawa.;Stefan Leucht.;Henricus G Ruhe.;Erick H Turner.;Julian P T Higgins.;Matthias Egger.;Nozomi Takeshima.;Yu Hayasaka.;Hissei Imai.;Kiyomi Shinohara.;Aran Tajika.;John P A Ioannidis.;John R Geddes.
来源: Lancet. 2018年391卷10128期1357-1366页
Major depressive disorder is one of the most common, burdensome, and costly psychiatric disorders worldwide in adults. Pharmacological and non-pharmacological treatments are available; however, because of inadequate resources, antidepressants are used more frequently than psychological interventions. Prescription of these agents should be informed by the best available evidence. Therefore, we aimed to update and expand our previous work to compare and rank antidepressants for the acute treatment of adults with unipolar major depressive disorder.
77. Atraumatic versus conventional lumbar puncture needles: a systematic review and meta-analysis.
作者: Siddharth Nath.;Alex Koziarz.;Jetan H Badhiwala.;Waleed Alhazzani.;Roman Jaeschke.;Sunjay Sharma.;Laura Banfield.;Ashkan Shoamanesh.;Sheila Singh.;Farshad Nassiri.;Wieslaw Oczkowski.;Emilie Belley-Côté.;Ray Truant.;Kesava Reddy.;Maureen O Meade.;Forough Farrokhyar.;Malgorzata M Bala.;Fayez Alshamsi.;Mette Krag.;Itziar Etxeandia-Ikobaltzeta.;Regina Kunz.;Osamu Nishida.;Charles Matouk.;Magdy Selim.;Andrew Rhodes.;Gregory Hawryluk.;Saleh A Almenawer.
来源: Lancet. 2018年391卷10126期1197-1204页
Atraumatic needles have been proposed to lower complication rates after lumbar puncture. However, several surveys indicate that clinical adoption of these needles remains poor. We did a systematic review and meta-analysis to compare patient outcomes after lumbar puncture with atraumatic needles and conventional needles.
78. Morbidity and mortality in homeless individuals, prisoners, sex workers, and individuals with substance use disorders in high-income countries: a systematic review and meta-analysis.
作者: Robert W Aldridge.;Alistair Story.;Stephen W Hwang.;Merete Nordentoft.;Serena A Luchenski.;Greg Hartwell.;Emily J Tweed.;Dan Lewer.;Srinivasa Vittal Katikireddi.;Andrew C Hayward.
来源: Lancet. 2018年391卷10117期241-250页
Inclusion health focuses on people in extremely poor health due to poverty, marginalisation, and multimorbidity. We aimed to review morbidity and mortality data on four overlapping populations who experience considerable social exclusion: homeless populations, individuals with substance use disorders, sex workers, and imprisoned individuals.
79. Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies.
作者: Siew C Ng.;Hai Yun Shi.;Nima Hamidi.;Fox E Underwood.;Whitney Tang.;Eric I Benchimol.;Remo Panaccione.;Subrata Ghosh.;Justin C Y Wu.;Francis K L Chan.;Joseph J Y Sung.;Gilaad G Kaplan.
来源: Lancet. 2017年390卷10114期2769-2778页
Inflammatory bowel disease is a global disease in the 21st century. We aimed to assess the changing incidence and prevalence of inflammatory bowel disease around the world.
80. Comparative efficacy and safety of reperfusion therapy with fibrinolytic agents in patients with ST-segment elevation myocardial infarction: a systematic review and network meta-analysis.
作者: Peerawat Jinatongthai.;Junporn Kongwatcharapong.;Chee Yoong Foo.;Arintaya Phrommintikul.;Surakit Nathisuwan.;Ammarin Thakkinstian.;Christopher M Reid.;Nathorn Chaiyakunapruk.
来源: Lancet. 2017年390卷10096期747-759页
Fibrinolytic therapy offers an alternative to mechanical reperfusion for ST-segment elevation myocardial infarction (STEMI) in settings where health-care resources are scarce. Comprehensive evidence comparing different agents is still unavailable. In this study, we examined the effects of various fibrinolytic drugs on clinical outcomes.
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