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61. Clinical Effectiveness of Cognitively Enhanced Tai Ji Quan Training on Global Cognition and Dual-Task Performance During Walking in Older Adults With Mild Cognitive Impairment or Self-Reported Memory Concerns : A Randomized Controlled Trial.
作者: Fuzhong Li.;Peter Harmer.;Elizabeth Eckstrom.;Kathleen Fitzgerald.;Kerri Winters-Stone.
来源: Ann Intern Med. 2023年176卷11期1498-1507页
Mild cognitive impairment (MCI) negatively impacts cognition and dual-task abilities. A physical-cognitive integrated treatment approach could mitigate this risk for dementia.
62. Once-Weekly Insulin Icodec With Dosing Guide App Versus Once-Daily Basal Insulin Analogues in Insulin-Naive Type 2 Diabetes (ONWARDS 5) : A Randomized Trial.
作者: Harpreet S Bajaj.;Jens Aberle.;Melanie Davies.;Anders Meller Donatsky.;Marie Frederiksen.;Dilek G Yavuz.;Amoolya Gowda.;Ildiko Lingvay.;Bruce Bode.
来源: Ann Intern Med. 2023年176卷11期1476-1485页
Inadequate dose titration and poor adherence to basal insulin can lead to suboptimal glycemic control in persons with type 2 diabetes (T2D). Once-weekly insulin icodec (icodec) is a basal insulin analogue that is in development and is aimed at reducing treatment burden.
63. Role of Artificial Intelligence in Colonoscopy Detection of Advanced Neoplasias : A Randomized Trial.
作者: Carolina Mangas-Sanjuan.;Luisa de-Castro.;Joaquín Cubiella.;Pilar Díez-Redondo.;Adolfo Suárez.;María Pellisé.;Nereida Fernández.;Sara Zarraquiños.;Henar Núñez-Rodríguez.;Verónica Álvarez-García.;Oswaldo Ortiz.;Noelia Sala-Miquel.;Pedro Zapater.;Rodrigo Jover.; .
来源: Ann Intern Med. 2023年176卷9期1145-1152页
The role of computer-aided detection in identifying advanced colorectal neoplasia is unknown.
64. Comparative Effectiveness and Safety of Generic Versus Brand-Name Fluticasone-Salmeterol to Treat Chronic Obstructive Pulmonary Disease.
作者: William B Feldman.;Aaron S Kesselheim.;Jerry Avorn.;Massimiliano Russo.;Shirley V Wang.
来源: Ann Intern Med. 2023年176卷8期1047-1056页
In 2019, the U.S. Food and Drug Administration (FDA) approved the first generic maintenance inhaler for asthma and chronic obstructive pulmonary disease (COPD). The inhaler, Wixela Inhub (fluticasone-salmeterol; Viatris), is a substitutable version of the dry powder inhaler Advair Diskus (fluticasone-salmeterol; GlaxoSmithKline). When approving complex generic products like inhalers, the FDA applies a special "weight-of-evidence" approach. In this case, manufacturers were required to perform a randomized controlled trial in patients with asthma but not COPD, although the product received approval for both indications.
65. Impact of Social Needs Case Management on Use of Medical and Behavioral Health Services: Secondary Analysis of a Randomized Controlled Trial.
作者: Mark D Fleming.;Crystal Guo.;Margae Knox.;Daniel M Brown.;Elizabeth A Hernandez.;Amanda L Brewster.
来源: Ann Intern Med. 2023年176卷8期1139-1141页 66. Time-Restricted Eating Without Calorie Counting for Weight Loss in a Racially Diverse Population : A Randomized Controlled Trial.
作者: Shuhao Lin.;Sofia Cienfuegos.;Mark Ezpeleta.;Kelsey Gabel.;Vasiliki Pavlou.;Andrea Mulas.;Kaitie Chakos.;Mara McStay.;Jackie Wu.;Lisa Tussing-Humphreys.;Shaina J Alexandria.;Julienne Sanchez.;Terry Unterman.;Krista A Varady.
来源: Ann Intern Med. 2023年176卷7期885-895页
Time-restricted eating (TRE), without calorie counting, has become a popular weight loss strategy, yet long-term randomized trials evaluating its efficacy are limited.
67. Acupuncture and Doxylamine-Pyridoxine for Nausea and Vomiting in Pregnancy : A Randomized, Controlled, 2 × 2 Factorial Trial.
作者: Xiao-Ke Wu.;Jing-Shu Gao.;Hong-Li Ma.;Yu Wang.;Bei Zhang.;Zhao-Lan Liu.;Jian Li.;Jing Cong.;Hui-Chao Qin.;Xin-Ming Yang.;Qi Wu.;Xiao-Yong Chen.;Zong-Lin Lu.;Ya-Hong Feng.;Xue Qi.;Yan-Xiang Wang.;Lan Yu.;Ying-Mei Cui.;Chun-Mei An.;Li-Li Zhou.;Yu-Hong Hu.;Lu Li.;Yi-Juan Cao.;Ying Yan.;Li Liu.;Yu-Xiu Liu.;Zhi-Shun Liu.;Rebecca C Painter.;Ernest H Y Ng.;Jian-Ping Liu.;Ben Willem J Mol.;Chi Chiu Wang.
来源: Ann Intern Med. 2023年176卷7期922-933页
An effective and safe treatment for nausea and vomiting of pregnancy (NVP) is lacking.
68. Effect of Low-Dose Aspirin Versus Placebo on Incidence of Anemia in the Elderly : A Secondary Analysis of the Aspirin in Reducing Events in the Elderly Trial.
作者: Zoe K McQuilten.;Le Thi Phuong Thao.;Sant-Rayn Pasricha.;Andrew S Artz.;Michael Bailey.;Andrew T Chan.;Harvey Jay Cohen.;Jessica E Lockery.;Anne M Murray.;Mark R Nelson.;Hans G Schneider.;Rory Wolfe.;Robyn L Woods.;Erica M Wood.;John J McNeil.
来源: Ann Intern Med. 2023年176卷7期913-921页
Daily low-dose aspirin increases major bleeding; however, few studies have investigated its effect on iron deficiency and anemia.
69. Effects of Implementation of a Supervised Walking Program in Veterans Affairs Hospitals : A Stepped-Wedge, Cluster Randomized Trial.
作者: Susan N Hastings.;Karen M Stechuchak.;Ashley Choate.;Courtney Harold Van Houtven.;Kelli D Allen.;Virginia Wang.;Cathleen Colón-Emeric.;George L Jackson.;Teresa M Damush.;Cassie Meyer.;Caitlin B Kappler.;Helen Hoenig.;Nina Sperber.;Cynthia J Coffman.
来源: Ann Intern Med. 2023年176卷6期743-750页
In trials, hospital walking programs have been shown to improve functional ability after discharge, but little evidence exists about their effectiveness under routine practice conditions.
70. Association of Low-Dose Colchicine With Incidence of Knee and Hip Replacements : Exploratory Analyses From a Randomized, Controlled, Double-Blind Trial.
作者: Michelle W J Heijman.;Aernoud T L Fiolet.;Arend Mosterd.;Jan G P Tijssen.;Bart J F van den Bemt.;Astrid Schut.;John W Eikelboom.;Peter L Thompson.;Cornelia H M van den Ende.;Stefan M Nidorf.;Calin D Popa.;Jan H Cornel.
来源: Ann Intern Med. 2023年176卷6期737-742页
Osteoarthritis is a major contributor to pain and disability worldwide. Given that inflammation plays an important role in the development of osteoarthritis, anti-inflammatory drugs may slow disease progression.
71. Population-Wide Screening for Chronic Kidney Disease : A Cost-Effectiveness Analysis.
作者: Marika M Cusick.;Rebecca L Tisdale.;Glenn M Chertow.;Douglas K Owens.;Jeremy D Goldhaber-Fiebert.
来源: Ann Intern Med. 2023年176卷6期788-797页
Sodium-glucose cotransporter-2 (SGLT2) inhibitors have the potential to alter the natural history of chronic kidney disease (CKD), and they should be included in cost-effectiveness analyses of screening for CKD.
72. Effects of Cognitive Behavioral Therapy and Cash Transfers on Older Persons Living Alone in India : A Randomized Trial.
作者: Madeline McKelway.;Abhijit Banerjee.;Erin Grela.;Frank Schilbach.;Miriam Sequeira.;Garima Sharma.;Girija Vaidyanathan.;Esther Duflo.
来源: Ann Intern Med. 2023年176卷5期632-641页
A growing number of older persons in developing countries live entirely alone and are physically, mentally, and financially vulnerable.
73. Hypotension-Avoidance Versus Hypertension-Avoidance Strategies in Noncardiac Surgery : An International Randomized Controlled Trial.
作者: Maura Marcucci.;Thomas W Painter.;David Conen.;Vladimir Lomivorotov.;Daniel I Sessler.;Matthew T V Chan.;Flavia K Borges.;Kate Leslie.;Emmanuelle Duceppe.;María José Martínez-Zapata.;Chew Yin Wang.;Denis Xavier.;Sandra N Ofori.;Michael Ke Wang.;Sergey Efremov.;Giovanni Landoni.;Ydo V Kleinlugtenbelt.;Wojciech Szczeklik.;Denis Schmartz.;Amit X Garg.;Timothy G Short.;Maria Wittmann.;Christian S Meyhoff.;Mohammed Amir.;David Torres.;Ameen Patel.;Kurt Ruetzler.;Joel L Parlow.;Vikas Tandon.;Edith Fleischmann.;Carisi A Polanczyk.;Andre Lamy.;Raja Jayaram.;Sergey V Astrakov.;William Ka Kei Wu.;Chao Chia Cheong.;Sabry Ayad.;Mikhail Kirov.;Miriam de Nadal.;Valery V Likhvantsev.;Pilar Paniagua.;Hector J Aguado.;Kamal Maheshwari.;Richard P Whitlock.;Michael H McGillion.;Jessica Vincent.;Ingrid Copland.;Kumar Balasubramanian.;Bruce M Biccard.;Sadeesh Srinathan.;Samandar Ismoilov.;Shirley Pettit.;David Stillo.;Andrea Kurz.;Emilie P Belley-Côté.;Jessica Spence.;William F McIntyre.;Shrikant I Bangdiwala.;Gordon Guyatt.;Salim Yusuf.;P J Devereaux.; .
来源: Ann Intern Med. 2023年176卷5期605-614页
Among patients having noncardiac surgery, perioperative hemodynamic abnormalities are associated with vascular complications. Uncertainty remains about what intraoperative blood pressure to target and how to manage long-term antihypertensive medications perioperatively.
74. Oral Fluvoxamine With Inhaled Budesonide for Treatment of Early-Onset COVID-19 : A Randomized Platform Trial.
作者: Gilmar Reis.;Eduardo Augusto Dos Santos Moreira Silva.;Daniela Carla Medeiros Silva.;Lehana Thabane.;Vitoria Helena de Souza Campos.;Thiago Santiago Ferreira.;Castilho Vitor Quirino Dos Santos.;Ana Maria Ribeiro Nogueira.;Ana Paula Figueiredo Guimaraes Almeida.;Leonardo Cançado Monteiro Savassi.;Adhemar Dias de Figueiredo Neto.;Carina Bitarães.;Aline Cruz Milagres.;Eduardo Diniz Callegari.;Maria Izabel Campos Simplicio.;Luciene Barra Ribeiro.;Rosemary Oliveira.;Ofir Harari.;Lindsay A Wilson.;Jamie I Forrest.;Hinda Ruton.;Sheila Sprague.;Paula McKay.;Christina M Guo.;Gordon H Guyatt.;Craig R Rayner.;David R Boulware.;Nicole Ezer.;Todd C Lee.;Emily Gibson McDonald.;Mona Bafadhel.;Christopher Butler.;Josue Rodrigues Silva.;Mark Dybul.;Edward J Mills.; .
来源: Ann Intern Med. 2023年176卷5期667-675页
Previous trials have demonstrated the effects of fluvoxamine alone and inhaled budesonide alone for prevention of disease progression among outpatients with COVID-19.
75. Safety and Efficacy of Combination SARS-CoV-2 Neutralizing Monoclonal Antibodies Amubarvimab Plus Romlusevimab in Nonhospitalized Patients With COVID-19.
作者: Teresa H Evering.;Kara W Chew.;Mark J Giganti.;Carlee Moser.;Mauricio Pinilla.;David Alain Wohl.;Judith S Currier.;Joseph J Eron.;Arzhang Cyrus Javan.;Rachel Bender Ignacio.;David Margolis.;Qing Zhu.;Ji Ma.;Lijie Zhong.;Li Yan.;Ulises D'Andrea Nores.;Keila Hoover.;Bharat Mocherla.;Manish C Choudhary.;Rinki Deo.;Justin Ritz.;William A Fischer.;Courtney V Fletcher.;Jonathan Z Li.;Michael D Hughes.;Davey Smith.;Eric S Daar.; .
来源: Ann Intern Med. 2023年176卷5期658-666页
Development of safe and effective SARS-CoV-2 therapeutics is a high priority. Amubarvimab and romlusevimab are noncompeting anti-SARS-CoV-2 monoclonal antibodies with an extended half-life.
76. Facilitating Shared Decision Making Among Black Patients at Risk for Sudden Cardiac Arrest : A Randomized Clinical Trial.
作者: Kevin L Thomas.;Sana M Al-Khatib.;Andrzej S Kosinski.;Samuel F Sears.;Nancy M Allen LaPointe.;Larry R Jackson.;Daniel D Matlock.;Daniel Haithcock.;B Judson Colley.;David S Hirsh.;Eric D Peterson.
来源: Ann Intern Med. 2023年176卷5期615-623页
Racial disparities in implantable cardioverter-defibrillator (ICD) implantation are multifactorial and are partly explained by higher refusal rates.
77. Effect of Thromboprophylaxis on Clinical Outcomes After COVID-19 Hospitalization.
作者: Tracy Y Wang.;Abdus S Wahed.;Alison Morris.;Lisa Baumann Kreuziger.;John G Quigley.;Gervasio A Lamas.;Alexandra J Weissman.;Jose Lopez-Sendon.;M Margaret Knudson.;Deborah M Siegal.;Raj S Kasthuri.;Andrew J Alexander.;Lana Wahid.;Bassel Atassi.;Peter J Miller.;Janice W Lawson.;Bela Patel.;Jerry A Krishnan.;Nancy L Shapiro.;Deborah E Martin.;Andrei L Kindzelski.;Eric S Leifer.;Jungnam Joo.;Lingyun Lyu.;Annie Pennella.;Brendan M Everett.;Mark W Geraci.;Kevin J Anstrom.;Thomas L Ortel.; .
来源: Ann Intern Med. 2023年176卷4期515-523页
Patients hospitalized with COVID-19 have an increased incidence of thromboembolism. The role of extended thromboprophylaxis after hospital discharge is unclear.
78. Comparison of Over-the-Scope Clips to Standard Endoscopic Treatment as the Initial Treatment in Patients With Bleeding From a Nonvariceal Upper Gastrointestinal Cause : A Randomized Controlled Trial.
作者: James Y W Lau.;Rui Li.;Chen-Huan Tan.;Xiu-Jing Sun.;Hao-Jun Song.;Lan Li.;Feng Ji.;Bu-Jiang Wang.;Dong-Tao Shi.;Wai K Leung.;Imogen Hartley.;Alan Moss.;Karina Y Y Yu.;Bing Y Suen.;Peng Li.;Francis K L Chan.
来源: Ann Intern Med. 2023年176卷4期455-462页
Current endoscopic methods in the control of acute nonvariceal bleeding have a small but clinically significant failure rate. The role of over-the-scope clips (OTSCs) as the first treatment has not been defined.
79. Cold Versus Hot Snare Polypectomy for Small Colorectal Polyps : A Pragmatic Randomized Controlled Trial.
作者: Li-Chun Chang.;Chi-Yang Chang.;Chi-Yi Chen.;Cheng-Hao Tseng.;Peng-Jen Chen.;Chia-Tung Shun.;Wen-Feng Hsu.;Yen-Nien Chen.;Chieh-Chang Chen.;Tien-Yu Huang.;Chia-Hung Tu.;Mei-Jyh Chen.;Chu-Kuang Chou.;Ching-Tai Lee.;Po-Yueh Chen.;Ming-Shiang Wu.;Han-Mo Chiu.
来源: Ann Intern Med. 2023年176卷3期311-319页
Although cold snare polypectomy (CSP) is considered effective in reducing delayed postpolypectomy bleeding risk, direct evidence supporting its safety in the general population remains lacking.
80. High- Versus Low-Dose Exercise Therapy for Knee Osteoarthritis : A Randomized Controlled Multicenter Trial.
作者: Tom Arild Torstensen.;Håvard Østerås.;Riccardo LoMartire.;Georg Mørtvedt Rugelbak.;Wilhelmus Johannes Andreas Grooten.;Björn Olov Äng.
来源: Ann Intern Med. 2023年176卷2期154-165页
The benefits of exercise in patients with knee osteoarthritis are well documented, but the optimal exercise dose remains unknown.
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