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61. Clinical Phenotypes of Atopy and Asthma in COPD: A Meta-analysis of SPIROMICS and COPDGene.
作者: Nirupama Putcha.;Ashraf Fawzy.;Elizabeth C Matsui.;Mark C Liu.;Russ P Bowler.;Prescott G Woodruff.;Wanda K O'Neal.;Alejandro P Comellas.;MeiLan K Han.;Mark T Dransfield.;J Michael Wells.;Njira Lugogo.;Li Gao.;C Conover Talbot.;Eric A Hoffman.;Christopher B Cooper.;Laura M Paulin.;Richard E Kanner.;Gerard Criner.;Victor E Ortega.;R Graham Barr.;Jerry A Krishnan.;Fernando J Martinez.;M Bradley Drummond.;Robert A Wise.;Gregory B Diette.;Craig P Hersh.;Nadia N Hansel.
来源: Chest. 2020年158卷6期2333-2345页
Little is known about the concordance of atopy with asthma COPD overlap. Among individuals with COPD, a better understanding of the phenotypes characterized by asthma overlap and atopy is needed to better target therapies.
62. Sensitivity and Safety of Electromagnetic Navigation Bronchoscopy for Lung Cancer Diagnosis: Systematic Review and Meta-analysis.
作者: Erik E Folch.;Gonzalo Labarca.;Daniel Ospina-Delgado.;Fayez Kheir.;Adnan Majid.;Sandeep J Khandhar.;Hiren J Mehta.;Michael A Jantz.;Sebastian Fernandez-Bussy.
来源: Chest. 2020年158卷4期1753-1769页
Bronchoscopy is a useful tool for the diagnosis of lesions near central airways; however, the diagnostic accuracy of these procedures for peripheral pulmonary lesions (PPLs) is a matter of ongoing debate. In this setting, electromagnetic navigation bronchoscopy (ENB) is a technique used to navigate and obtain samples from these lesions. This systematic review and meta-analysis aims to explore the sensitivity of ENB in patients with PPLs suspected of lung cancer.
63. Serum IgG Levels and Risk of COPD Hospitalization: A Pooled Meta-analysis.
作者: Fernando Sergio Leitao Filho.;Andre Mattman.;Robert Schellenberg.;Gerard J Criner.;Prescott Woodruff.;Stephen C Lazarus.;Richard K Albert.;John Connett.;Meilan K Han.;Steven E Gay.;Fernando J Martinez.;Anne L Fuhlbrigge.;James K Stoller.;Neil R MacIntyre.;Richard Casaburi.;Philip Diaz.;Ralph J Panos.;J Allen Cooper.;William C Bailey.;David C LaFon.;Frank C Sciurba.;Richard E Kanner.;Roger D Yusen.;David H Au.;Kenneth C Pike.;Vincent S Fan.;Janice M Leung.;Shu-Fan Paul Man.;Shawn D Aaron.;Robert M Reed.;Don D Sin.
来源: Chest. 2020年158卷4期1420-1430页
Hypogammaglobulinemia (serum IgG levels < 7.0 g/L) has been associated with increased risk of COPD exacerbations but has not yet been shown to predict hospitalizations.
64. Efficacy of CPAP for Improvements in Sleepiness, Cognition, Mood, and Quality of Life in Elderly Patients With OSA: Systematic Review and Meta-analysis of Randomized Controlled Trials.
作者: Gonzalo Labarca.;Daniela Saavedra.;Jorge Dreyse.;Jorge Jorquera.;Ferran Barbe.
来源: Chest. 2020年158卷2期751-764页
OSA is found commonly in the elderly population (≥65 years old), and CPAP improves sleepiness and health-related quality of life (HRQoL) in the middle-aged population; however, data about its efficacy in elderly patients are unclear. The purpose of this study was to evaluate the efficacy of CPAP for sleepiness, HRQoL, mood, and cognition in elderly patients with OSA.
65. Change in V˙O2peak in Response to Aerobic Exercise Training and the Relationship With Exercise Prescription in People With COPD: A Systematic Review and Meta-analysis.
作者: Thomas J C Ward.;Charles D Plumptre.;Thomas E Dolmage.;Amy V Jones.;Ruth Trethewey.;Pip Divall.;Sally J Singh.;Martin R Lindley.;Michael C Steiner.;Rachael A Evans.
来源: Chest. 2020年158卷1期131-144页
Despite the wide-ranging benefits of pulmonary rehabilitation, conflicting results remain regarding whether people with COPD can improve their peak oxygen uptake (V˙O2peak) with aerobic training.
66. Lower vs Higher Fluid Volumes During Initial Management of Sepsis: A Systematic Review With Meta-Analysis and Trial Sequential Analysis.
作者: Tine Sylvest Meyhoff.;Morten Hylander Møller.;Peter Buhl Hjortrup.;Maria Cronhjort.;Anders Perner.;Jørn Wetterslev.
来源: Chest. 2020年157卷6期1478-1496页
IV fluids are recommended during the initial management of sepsis, but the quality of evidence is low, and clinical equipoise exists. We aimed to assess patient-important benefits and harms of lower vs higher fluid volumes in adult patients with sepsis.
67. Respiratory Disease and Lower Pulmonary Function as Risk Factors for Dementia: A Systematic Review With Meta-analysis.
In addition to affecting the oxygen supply to the brain, pulmonary function is a marker of multiple insults throughout life (including smoking, illness, and socioeconomic deprivation). In this meta-analysis of existing longitudinal studies, the hypothesis that lower pulmonary function and respiratory illness are linked to an elevated risk of dementia was tested.
68. Sensitivity of Radial Endobronchial Ultrasound-Guided Bronchoscopy for Lung Cancer in Patients With Peripheral Pulmonary Lesions: An Updated Meta-analysis.
作者: Paula V Sainz Zuñiga.;Erik Vakil.;Sofia Molina.;Roland L Bassett.;David E Ost.
来源: Chest. 2020年157卷4期994-1011页
Registry trials have found radial endobronchial ultrasound (r-EBUS) sensitivity to vary between institutions, suggesting that in clinical practice, r-EBUS sensitivity may be lower than reported in clinical trials. We performed a meta-analysis to update the estimates of r-EBUS sensitivity and to explore factors contributing to heterogeneity of results.
69. Viral Infection Increases the Risk of Idiopathic Pulmonary Fibrosis: A Meta-Analysis.
作者: Gaohong Sheng.;Peng Chen.;Yanqiu Wei.;Huihui Yue.;Jiaojiao Chu.;Jianping Zhao.;Yihua Wang.;Wanguang Zhang.;Hui-Lan Zhang.
来源: Chest. 2020年157卷5期1175-1187页
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrotic lung disease with a poor prognosis. Although many factors have been identified that possibly trigger or aggravate IPF, such as viral infection, the exact cause of IPF remains unclear. Until now, there has been no systematic review to assess the role of viral infection in IPF quantitatively.
70. Pleural Cryobiopsy: A Systematic Review and Meta-Analysis.
作者: Majid Shafiq.;Jaskaran Sethi.;Muhammad S Ali.;Uzair K Ghori.;Tajalli Saghaie.;Erik Folch.
来源: Chest. 2020年157卷1期223-230页
Pleural biopsy using either video-assisted thoracoscopic surgery or medical pleuroscopy is the current diagnostic criterion standard for pleural pathology with a high, yet imperfect, diagnostic yield. Cryobiopsy may provide greater tissue, increase depth of sampled tissue, and/or reduce crush artifact. However, its impact on diagnostic yield remains uncertain, and there are potential concerns regarding its safety too. We performed a systematic review and meta-analysis to investigate the same.
71. Prevalence and Risk Factors for Osteoporosis in Individuals With COPD: A Systematic Review and Meta-analysis.
作者: Yi-Wen Chen.;Andrew H Ramsook.;Harvey O Coxson.;Jessica Bon.;W Darlene Reid.
来源: Chest. 2019年156卷6期1092-1110页
Osteoporosis is prevalent in individuals with COPD. Updated evidence is required to complement the previous systematic review on this topic to provide best practice. The aim of this systematic review and meta-analysis was to quantitatively synthesize data from studies with respect to the prevalence and risk factors for osteoporosis among individuals with COPD.
72. Extended Anticoagulation for VTE: A Systematic Review and Meta-Analysis.
作者: Vicky Mai.;Charles-Antoine Guay.;Laurie Perreault.;Sébastien Bonnet.;Laurent Bertoletti.;Yves Lacasse.;Sabine Jardel.;Jean-Christophe Lega.;Steeve Provencher.
来源: Chest. 2019年155卷6期1199-1216页
The efficacy and safety of direct oral anticoagulants (DOACs) and vitamin K antagonists (VKAs) during extended anticoagulation for a VTE remains largely unknown, especially in terms of potential survival benefit. The goal of this study was to assess the effects of VKAs and DOACs on overall mortality and VTE-related mortality, as well as VTE recurrence and safety.
73. Prognostic Value of Sarcopenia in Lung Cancer: A Systematic Review and Meta-analysis.
Evidence regarding the association between sarcopenia (skeletal muscle depletion) and outcomes in patients with lung cancer varies across studies. We aimed to systematically review the prognostic value of sarcopenia in lung cancer.
74. Effect of Pulmonary Rehabilitation on Symptoms of Anxiety and Depression in COPD: A Systematic Review and Meta-Analysis.
作者: Carla S Gordon.;Jacob W Waller.;Rylee M Cook.;Steffan L Cavalera.;Wing T Lim.;Christian R Osadnik.
来源: Chest. 2019年156卷1期80-91页
Pulmonary rehabilitation (PR) improves exercise capacity and quality of life in people with COPD; however, its effect on anxiety and depression symptoms is less clear. Existing data are difficult to apply to clinical PR because of diverse interventions and comparators. This review evaluated the effectiveness of PR on anxiety and depression symptoms in people with COPD.
75. Comparison of All-Cause Mortality Following VTE Treatment Between Propensity Score-Adjusted Observational Studies and Matched Randomized Controlled Trials: Meta-Epidemiologic Study.
作者: Claudia Coscia.;Ana Jaureguizar.;Carlos Andres Quezada.;Alfonso Muriel.;Manuel Monreal.;Tomas Villén.;Esther Barbero.;Diana Chiluiza.;Roger D Yusen.;David Jimenez.
来源: Chest. 2019年155卷4期689-698页
It is unknown whether propensity score-adjusted observational studies produce results comparable to those of randomized controlled trials (RCTs) that address similar VTE treatment issues.
76. Use of Balloon Atrial Septostomy in Patients With Advanced Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis.
作者: Muhammad Shahzeb Khan.;Muhammad Mustafa Memon.;Emaan Amin.;Naser Yamani.;Safi U Khan.;Vincent M Figueredo.;Salil Deo.;Jonathan D Rich.;Raymond L Benza.;Richard A Krasuski.
来源: Chest. 2019年156卷1期53-63页
Despite the use and purported benefits of balloon atrial septostomy (BAS), its safety, efficacy, and therapeutic role in the setting of advanced pulmonary arterial hypertension (PAH) are not well defined.
77. Procalcitonin-Guided Antibiotic Discontinuation and Mortality in Critically Ill Adults: A Systematic Review and Meta-analysis.
作者: Dominique J Pepper.;Junfeng Sun.;Chanu Rhee.;Judith Welsh.;John H Powers.;Robert L Danner.;Sameer S Kadri.
来源: Chest. 2019年155卷6期1109-1118页
Procalcitonin (PCT)-guided antibiotic discontinuation appears to decrease antibiotic use in critically ill patients, but its impact on survival remains less certain.
78. Lytic Therapy for Retained Traumatic Hemothorax: A Systematic Review and Meta-analysis.
作者: Brandon S Hendriksen.;Marcos T Kuroki.;Scott B Armen.;Michael F Reed.;Matthew D Taylor.;Christopher S Hollenbeak.
来源: Chest. 2019年155卷4期805-815页
Intrapleural lytic therapy has been established as an important modality of treatment for many pleural disorders, including hemothorax and empyema. Retained traumatic hemothorax is a common and understudied subset of pleural disease. The current standard of care for retained traumatic hemothorax is operative management. The use of lytic therapy for avoidance of operative intervention in the trauma population has not been well established.
79. Adding a LAMA to ICS/LABA Therapy: A Meta-analysis of Triple Combination Therapy in COPD.
作者: Luigino Calzetta.;Mario Cazzola.;Maria Gabriella Matera.;Paola Rogliani.
来源: Chest. 2019年155卷4期758-770页
Inhaled corticosteroid (ICS)/long-acting β2-agonist (LABA) combination is commonly prescribed to treat COPD; therefore, we performed a meta-analysis on the effect of adding a long-acting muscarinic receptor antagonist (LAMA) to ICS/LABA combination in COPD.
80. The Accuracy of Clinical Staging of Stage I-IIIa Non-Small Cell Lung Cancer: An Analysis Based on Individual Participant Data.
作者: Neal Navani.;David J Fisher.;Jayne F Tierney.;Richard J Stephens.;Sarah Burdett.; .
来源: Chest. 2019年155卷3期502-509页
Clinical staging of non-small cell lung cancer (NSCLC) helps determine the prognosis and treatment of patients; few data exist on the accuracy of clinical staging and the impact on treatment and survival of patients. We assessed whether participant or trial characteristics were associated with clinical staging accuracy as well as impact on survival.
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