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61. Lower vs Higher Fluid Volumes During Initial Management of Sepsis: A Systematic Review With Meta-Analysis and Trial Sequential Analysis.
作者: Tine Sylvest Meyhoff.;Morten Hylander Møller.;Peter Buhl Hjortrup.;Maria Cronhjort.;Anders Perner.;Jørn Wetterslev.
来源: Chest. 2020年157卷6期1478-1496页
IV fluids are recommended during the initial management of sepsis, but the quality of evidence is low, and clinical equipoise exists. We aimed to assess patient-important benefits and harms of lower vs higher fluid volumes in adult patients with sepsis.
62. Respiratory Disease and Lower Pulmonary Function as Risk Factors for Dementia: A Systematic Review With Meta-analysis.
In addition to affecting the oxygen supply to the brain, pulmonary function is a marker of multiple insults throughout life (including smoking, illness, and socioeconomic deprivation). In this meta-analysis of existing longitudinal studies, the hypothesis that lower pulmonary function and respiratory illness are linked to an elevated risk of dementia was tested.
63. Sensitivity of Radial Endobronchial Ultrasound-Guided Bronchoscopy for Lung Cancer in Patients With Peripheral Pulmonary Lesions: An Updated Meta-analysis.
作者: Paula V Sainz Zuñiga.;Erik Vakil.;Sofia Molina.;Roland L Bassett.;David E Ost.
来源: Chest. 2020年157卷4期994-1011页
Registry trials have found radial endobronchial ultrasound (r-EBUS) sensitivity to vary between institutions, suggesting that in clinical practice, r-EBUS sensitivity may be lower than reported in clinical trials. We performed a meta-analysis to update the estimates of r-EBUS sensitivity and to explore factors contributing to heterogeneity of results.
64. Viral Infection Increases the Risk of Idiopathic Pulmonary Fibrosis: A Meta-Analysis.
作者: Gaohong Sheng.;Peng Chen.;Yanqiu Wei.;Huihui Yue.;Jiaojiao Chu.;Jianping Zhao.;Yihua Wang.;Wanguang Zhang.;Hui-Lan Zhang.
来源: Chest. 2020年157卷5期1175-1187页
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrotic lung disease with a poor prognosis. Although many factors have been identified that possibly trigger or aggravate IPF, such as viral infection, the exact cause of IPF remains unclear. Until now, there has been no systematic review to assess the role of viral infection in IPF quantitatively.
65. Pleural Cryobiopsy: A Systematic Review and Meta-Analysis.
作者: Majid Shafiq.;Jaskaran Sethi.;Muhammad S Ali.;Uzair K Ghori.;Tajalli Saghaie.;Erik Folch.
来源: Chest. 2020年157卷1期223-230页
Pleural biopsy using either video-assisted thoracoscopic surgery or medical pleuroscopy is the current diagnostic criterion standard for pleural pathology with a high, yet imperfect, diagnostic yield. Cryobiopsy may provide greater tissue, increase depth of sampled tissue, and/or reduce crush artifact. However, its impact on diagnostic yield remains uncertain, and there are potential concerns regarding its safety too. We performed a systematic review and meta-analysis to investigate the same.
66. Prevalence and Risk Factors for Osteoporosis in Individuals With COPD: A Systematic Review and Meta-analysis.
作者: Yi-Wen Chen.;Andrew H Ramsook.;Harvey O Coxson.;Jessica Bon.;W Darlene Reid.
来源: Chest. 2019年156卷6期1092-1110页
Osteoporosis is prevalent in individuals with COPD. Updated evidence is required to complement the previous systematic review on this topic to provide best practice. The aim of this systematic review and meta-analysis was to quantitatively synthesize data from studies with respect to the prevalence and risk factors for osteoporosis among individuals with COPD.
67. Extended Anticoagulation for VTE: A Systematic Review and Meta-Analysis.
作者: Vicky Mai.;Charles-Antoine Guay.;Laurie Perreault.;Sébastien Bonnet.;Laurent Bertoletti.;Yves Lacasse.;Sabine Jardel.;Jean-Christophe Lega.;Steeve Provencher.
来源: Chest. 2019年155卷6期1199-1216页
The efficacy and safety of direct oral anticoagulants (DOACs) and vitamin K antagonists (VKAs) during extended anticoagulation for a VTE remains largely unknown, especially in terms of potential survival benefit. The goal of this study was to assess the effects of VKAs and DOACs on overall mortality and VTE-related mortality, as well as VTE recurrence and safety.
68. Prognostic Value of Sarcopenia in Lung Cancer: A Systematic Review and Meta-analysis.
Evidence regarding the association between sarcopenia (skeletal muscle depletion) and outcomes in patients with lung cancer varies across studies. We aimed to systematically review the prognostic value of sarcopenia in lung cancer.
69. Effect of Pulmonary Rehabilitation on Symptoms of Anxiety and Depression in COPD: A Systematic Review and Meta-Analysis.
作者: Carla S Gordon.;Jacob W Waller.;Rylee M Cook.;Steffan L Cavalera.;Wing T Lim.;Christian R Osadnik.
来源: Chest. 2019年156卷1期80-91页
Pulmonary rehabilitation (PR) improves exercise capacity and quality of life in people with COPD; however, its effect on anxiety and depression symptoms is less clear. Existing data are difficult to apply to clinical PR because of diverse interventions and comparators. This review evaluated the effectiveness of PR on anxiety and depression symptoms in people with COPD.
70. Comparison of All-Cause Mortality Following VTE Treatment Between Propensity Score-Adjusted Observational Studies and Matched Randomized Controlled Trials: Meta-Epidemiologic Study.
作者: Claudia Coscia.;Ana Jaureguizar.;Carlos Andres Quezada.;Alfonso Muriel.;Manuel Monreal.;Tomas Villén.;Esther Barbero.;Diana Chiluiza.;Roger D Yusen.;David Jimenez.
来源: Chest. 2019年155卷4期689-698页
It is unknown whether propensity score-adjusted observational studies produce results comparable to those of randomized controlled trials (RCTs) that address similar VTE treatment issues.
71. Use of Balloon Atrial Septostomy in Patients With Advanced Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis.
作者: Muhammad Shahzeb Khan.;Muhammad Mustafa Memon.;Emaan Amin.;Naser Yamani.;Safi U Khan.;Vincent M Figueredo.;Salil Deo.;Jonathan D Rich.;Raymond L Benza.;Richard A Krasuski.
来源: Chest. 2019年156卷1期53-63页
Despite the use and purported benefits of balloon atrial septostomy (BAS), its safety, efficacy, and therapeutic role in the setting of advanced pulmonary arterial hypertension (PAH) are not well defined.
72. Procalcitonin-Guided Antibiotic Discontinuation and Mortality in Critically Ill Adults: A Systematic Review and Meta-analysis.
作者: Dominique J Pepper.;Junfeng Sun.;Chanu Rhee.;Judith Welsh.;John H Powers.;Robert L Danner.;Sameer S Kadri.
来源: Chest. 2019年155卷6期1109-1118页
Procalcitonin (PCT)-guided antibiotic discontinuation appears to decrease antibiotic use in critically ill patients, but its impact on survival remains less certain.
73. Lytic Therapy for Retained Traumatic Hemothorax: A Systematic Review and Meta-analysis.
作者: Brandon S Hendriksen.;Marcos T Kuroki.;Scott B Armen.;Michael F Reed.;Matthew D Taylor.;Christopher S Hollenbeak.
来源: Chest. 2019年155卷4期805-815页
Intrapleural lytic therapy has been established as an important modality of treatment for many pleural disorders, including hemothorax and empyema. Retained traumatic hemothorax is a common and understudied subset of pleural disease. The current standard of care for retained traumatic hemothorax is operative management. The use of lytic therapy for avoidance of operative intervention in the trauma population has not been well established.
74. Adding a LAMA to ICS/LABA Therapy: A Meta-analysis of Triple Combination Therapy in COPD.
作者: Luigino Calzetta.;Mario Cazzola.;Maria Gabriella Matera.;Paola Rogliani.
来源: Chest. 2019年155卷4期758-770页
Inhaled corticosteroid (ICS)/long-acting β2-agonist (LABA) combination is commonly prescribed to treat COPD; therefore, we performed a meta-analysis on the effect of adding a long-acting muscarinic receptor antagonist (LAMA) to ICS/LABA combination in COPD.
75. The Accuracy of Clinical Staging of Stage I-IIIa Non-Small Cell Lung Cancer: An Analysis Based on Individual Participant Data.
作者: Neal Navani.;David J Fisher.;Jayne F Tierney.;Richard J Stephens.;Sarah Burdett.; .
来源: Chest. 2019年155卷3期502-509页
Clinical staging of non-small cell lung cancer (NSCLC) helps determine the prognosis and treatment of patients; few data exist on the accuracy of clinical staging and the impact on treatment and survival of patients. We assessed whether participant or trial characteristics were associated with clinical staging accuracy as well as impact on survival.
76. Change in FEV1 and Feno Measurements as Predictors of Future Asthma Outcomes in Children.
作者: Shona Fielding.;Marielle Pijnenburg.;Johan C de Jongste.;Katharine C Pike.;Graham Roberts.;Helen Petsky.;Anne B Chang.;Maria Fritsch.;Thomas Frischer.;Stanley Szefler.;Peter Gergen.;Francoise Vermeulen.;Robin Vael.;Steve Turner.
来源: Chest. 2019年155卷2期331-341页
Repeated measurements of spirometry and fractional exhaled nitric oxide (Feno) are recommended as part of the management of childhood asthma, but the evidence base for such recommendations is small. We tested the hypothesis that reducing spirometric indices or increasing Feno will predict poor future asthma outcomes.
77. Meta-analysis of Gastroesophageal Reflux Disease and Idiopathic Pulmonary Fibrosis.
The relationship between gastroesophageal reflux disease (GERD) and idiopathic pulmonary fibrosis (IPF) is controversial. Current guidelines recommend that clinicians use regular antacid treatment, while two recent meta-analyses of antacid therapy in IPF were inconclusive. The objective of this study was to examine the evidence regarding the association between GERD and IPF through a systematic review and a meta-analysis, with special reference to the methodologic quality of the observational studies.
78. Efficacy of Endosonographic Procedures in Mediastinal Restaging of Lung Cancer After Neoadjuvant Therapy: A Systematic Review and Diagnostic Accuracy Meta-Analysis.
作者: Valliappan Muthu.;Inderpaul S Sehgal.;Sahajal Dhooria.;Ashutosh N Aggarwal.;Ritesh Agarwal.
来源: Chest. 2018年154卷1期99-109页
The optimal modality for restaging the mediastinum following neoadjuvant therapy for lung cancer remains unclear. Surgical methods are currently considered the reference standard. The present study evaluates the role of endosonographic techniques for mediastinal restaging in lung cancer.
79. Treatment of Gastroesophageal Reflux in Patients With Idiopathic Pulmonary Fibrosis: A Systematic Review and Meta-Analysis.
Gastroesophageal reflux (GER) is common in patients with idiopathic pulmonary fibrosis (IPF) and has been proposed as a potential contributor to disease progression and exacerbation. Whether treatment of GER improves health outcomes in patients with IPF is controversial. Our objective was to review the efficacy and safety of GER treatments in IPF.
80. The Relationship Between COPD and Frailty: A Systematic Review and Meta-Analysis of Observational Studies.
作者: Alessandra Marengoni.;Davide L Vetrano.;Ester Manes-Gravina.;Roberto Bernabei.;Graziano Onder.;Katie Palmer.
来源: Chest. 2018年154卷1期21-40页
Frailty is common in seniors and is characterized by diminished physiological reserves and increased vulnerability to stressors. Frailty can change the prognosis and treatment approach of several chronic diseases, including COPD. The association between frailty and COPD has never been systematically reviewed.
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