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761. Ethical Guidance for Physicians and Health Care Institutions on Grateful Patient Fundraising: A Position Paper From the American College of Physicians.
作者: Lois Snyder Sulmasy.;T Brian Callister.;Isaac O Opole.;Noel N Deep.; .
来源: Ann Intern Med. 2023年176卷10期1392-1395页
Physician solicitation of charitable contributions from patients-also known among other things as grateful patient fundraising-raises significant ethical concerns. These include pressure on patients to donate and the effects of this on the patient-physician relationship, potential expectations of donor patients for treatment that is not indicated or preferential care, justice and fairness issues, disclosure and use of confidential patient information for nontreatment purposes, and conflicts of interest. The patient-physician relationship and knowledge of the patient's medical history, clinical status, personal information, and financial circumstances are some of the reasons development and administrative officials might see physicians as strong potential fundraisers. But those are among the reasons grateful patient fundraising is ethically problematic. This American College of Physicians position paper explores these issues and offers guidance.
762. Once-Weekly Insulin Icodec With Dosing Guide App Versus Once-Daily Basal Insulin Analogues in Insulin-Naive Type 2 Diabetes (ONWARDS 5) : A Randomized Trial.
作者: Harpreet S Bajaj.;Jens Aberle.;Melanie Davies.;Anders Meller Donatsky.;Marie Frederiksen.;Dilek G Yavuz.;Amoolya Gowda.;Ildiko Lingvay.;Bruce Bode.
来源: Ann Intern Med. 2023年176卷11期1476-1485页
Inadequate dose titration and poor adherence to basal insulin can lead to suboptimal glycemic control in persons with type 2 diabetes (T2D). Once-weekly insulin icodec (icodec) is a basal insulin analogue that is in development and is aimed at reducing treatment burden.
763. Blood Pressure Level in Late Adolescence and Risk for Cardiovascular Events : A Cohort Study.
作者: Helene Rietz.;Johanna Pennlert.;Peter Nordström.;Mattias Brunström.
来源: Ann Intern Med. 2023年176卷10期1289-1298页
Not enough is known about the association between blood pressure (BP) in adolescence and future cardiovascular events.
764. Outpatient Treatment of Confirmed COVID-19: A Living, Rapid Evidence Review for the American College of Physicians (Version 2).
作者: Isolde Sommer.;Dominic Ledinger.;Kylie Thaler.;Andreea Dobrescu.;Emma Persad.;Martin Fangmeyer.;Irma Klerings.;Gerald Gartlehner.
来源: Ann Intern Med. 2023年176卷10期1377-1385页
Clinicians and patients want to know the benefits and harms of outpatient treatment options for the Omicron variant of SARS-CoV-2.
765. Web Exclusive. Annals Video Summary - Outpatient Treatment of Confirmed COVID-19.
来源: Ann Intern Med. 2023年176卷10期eM232064页
This Annals Video Summary discusses the following article: “Outpatient Treatment of Confirmed COVID-19: A Living, Rapid Evidence Review for the American College of Physicians (Version 2)”
766. Outpatient Treatment of Confirmed COVID-19: Living, Rapid Practice Points From the American College of Physicians (Version 2).
作者: Amir Qaseem.;Jennifer Yost.;George M Abraham.;Rebecca Andrews.;Janet A Jokela.;Matthew C Miller.;Linda L Humphrey.; .;Andrew Dunn.;Ray Haeme.;Rachael Lee.;Sameer D Saini.;Cdr Mark P Tschanz.;Itziar Etxeandia-Ikobaltzeta.;Curtis Harrod.;Tatyana Shamliyan.;Karla Umana.
来源: Ann Intern Med. 2023年176卷10期1396-1404页
Evidence for the use of outpatient treatments in adults with confirmed COVID-19 continues to evolve with new data. This is version 2 of the American College of Physicians (ACP) living, rapid practice points focusing on 22 outpatient treatments for COVID-19, specifically addressing the dominant SARS-CoV-2 Omicron variant.
767. Chronotype, Unhealthy Lifestyle, and Diabetes Risk in Middle-Aged U.S. Women : A Prospective Cohort Study.
作者: Sina Kianersi.;Yue Liu.;Marta Guasch-Ferré.;Susan Redline.;Eva Schernhammer.;Qi Sun.;Tianyi Huang.
来源: Ann Intern Med. 2023年176卷10期1330-1339页
Evening chronotype may promote adherence to an unhealthy lifestyle and increase type 2 diabetes risk.
768. Travel Medicine.
International travel can cause new illness or exacerbate existing conditions. Because primary care providers are frequent sources of health advice to travelers, they should be familiar with destination-specific disease risks, be knowledgeable about travel and routine vaccines, be prepared to prescribe chemoprophylaxis and self-treatment regimens, and be aware of travel medicine resources. Primary care providers should recognize travelers who would benefit from referral to a specialized travel clinic for evaluation. Those requiring yellow fever vaccination, immunocompromised hosts, pregnant persons, persons with multiple comorbid conditions, or travelers with complex itineraries may warrant specialty referral.
769. Comparative Safety Analysis of Oral Antipsychotics for In-Hospital Adverse Clinical Events in Older Adults After Major Surgery : A Nationwide Cohort Study.
作者: Dae Hyun Kim.;Su Been Lee.;Chan Mi Park.;Raisa Levin.;Eran Metzger.;Brian T Bateman.;E Wesley Ely.;Pratik P Pandharipande.;Margaret A Pisani.;Richard N Jones.;Edward R Marcantonio.;Sharon K Inouye.
来源: Ann Intern Med. 2023年176卷9期1153-1162页
Antipsychotics are commonly used to manage postoperative delirium. Recent studies reported that haloperidol use has declined, and atypical antipsychotic use has increased over time.
770. Evidence-Based Cardiovascular Disease Medicines' Availability in Low-Cost Generic Drug Programs in the United States : A Cross-Sectional Study.
作者: Ivy T Ton.;Jungyeon Moon.;Anthony Sengul.;Freny Vaghaiwalla Mody.;Towhid Rahman.;Janet K Han.;Cynthia A Jackevicius.
来源: Ann Intern Med. 2023年176卷9期1190-1199页
Low-cost generic programs (LCGPs) that expand access to affordable cardiovascular disease (CVD) medicines can assist patients in achieving desired cardiovascular outcomes. It is important that LCGPs offer CVD medicines that promote evidence-based prescribing.
771. In treatment-resistant major depression, ketamine was noninferior to ECT for treatment response.
Anand A, Mathew SJ, Sanacora G, et al. Ketamine versus ECT for nonpsychotic treatment-resistant major depression. N Engl J Med. 2023;388:2315-2325. 37224232.
772. In moderate-to-severe Crohn disease, upadacitinib increased clinical remission at 12 and 52 wk.
Loftus EV Jr, Panés J, Lacerda AP, et al. Upadacitinib induction and maintenance therapy for Crohn's disease. N Engl J Med. 2023;388:1966-1980. 37224198.
773. The 3D-CAM 3-minute interview has 92% sensitivity and 95% specificity for detecting delirium in various care settings.
Ma R, Zhao J, Li C, et al. Diagnostic accuracy of the 3-minute diagnostic interview for confusion assessment method-defined delirium in delirium detection: a systematic review and meta-analysis. Age Ageing. 2023;52:afad074. 37211364.
774. In chronic HF, empagliflozin reduced a composite of CV death or HF hospitalization across kidney risk categories.
Butler J, Packer M, Siddiqi TJ, et al. Efficacy of empagliflozin in patients with heart failure across kidney risk categories. J Am Coll Cardiol. 2023;81:1902-1914. 37164523.
775. In HF, with or without PAD, dapagliflozin reduced a composite of worsening HF or CV death and did not increase amputations.
Butt JH, Kondo T, Yang M, et al. Heart failure, peripheral artery disease, and dapagliflozin: a patient-level meta-analysis of DAPA-HF and DELIVER. Eur Heart J. 2023;44:2170-2183. 37220172.
776. In adults with cancer and VTE, DOACs were noninferior to LMWH for recurrent, nonfatal VTE at 6 mo.
Schrag D, Uno H, Rosovsky R, et al; CANVAS Investigators. Direct oral anticoagulants vs low-molecular-weight heparin and recurrent VTE in patients with cancer: a randomized clinical trial. JAMA. 2023;329:1924-1933. 37266947.
777. SGLT2 inhibitors improved health status in Black and White patients with HF regardless of race.
Gupta K, Spertus JA, Birmingham M, et al. Racial differences in quality of life in patients with heart failure treated with sodium-glucose cotransporter 2 inhibitors: a patient-level meta-analysis of the CHIEF-HF, DEFINE-HF, and PRESERVED-HF trials. Circulation. 2023;148:220-228. 37191040.
778. CTFPHC recommends risk assessment-first screening to prevent fragility fractures in women aged ≥65 y.
Thériault G, Limburg H, Klarenbach S, et al; Canadian Task Force on Preventive Health Care. Recommendations on screening for primary prevention of fragility fractures. CMAJ. 2023;195:E639-E649. 37156553.
779. In older adults with frailty, virtual reality exercise training improves walking speed and balance.
Lee YH, Lin CH, Wu WR, et al. Virtual reality exercise programs ameliorate frailty and fall risks in older adults: a meta-analysis. J Am Geriatr Soc. 2023 May 10. [Epub ahead of print.] 37165743.
780. In COPD with type 2 inflammation despite inhaled triple therapy, dupilumab safely reduced exacerbations.
Bhatt SP, Rabe KF, Hanania NA, et al; BOREAS Investigators. Dupilumab for COPD with type 2 inflammation indicated by eosinophil counts. N Engl J Med. 2023;389;205-214.37272521.
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