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741. Patient-initiated hospital follow-up for rheumatoid arthritis.
作者: S Hewlett.;K Mitchell.;J Haynes.;T Paine.;E Korendowych.;J R Kirwan.
来源: Rheumatology (Oxford). 2000年39卷9期990-7页
To evaluate the clinical efficacy, cost and acceptability of a shared care system of patient- or general practitioner (GP)-initiated hospital review in rheumatoid arthritis (RA).
742. Reliability and sensitivity to change of various measures of hand function in relation to treatment of synovitis of the metacarpophalangeal joint in rheumatoid arthritis.
作者: P H Goossens.;B Heemskerk.;J van Tongeren.;A H Zwinderman.;T P Vliet Vlieland.;T W Huizinga.
来源: Rheumatology (Oxford). 2000年39卷8期909-13页
The reliability and discriminative capacity of hand function tests were studied in order to obtain tests suitable for the evaluation of local treatment of an arthritic metacarpophalangeal (MCP) joint.
743. Long-term efficacy of radon spa therapy in rheumatoid arthritis--a randomized, sham-controlled study and follow-up.
作者: A Franke.;L Reiner.;H G Pratzel.;T Franke.;K L Resch.
来源: Rheumatology (Oxford). 2000年39卷8期894-902页
To quantify the efficacy of a series of baths containing natural radon and carbon dioxide (1.3 kBq/l, 1.6 g carbon dioxide/l on average) versus artificial carbon dioxide baths alone in patients with rheumatoid arthritis.
744. Racial origin and its effect on disease expression and HLA-DRB1 types in patients with rheumatoid arthritis: a matched cross-sectional study.
作者: B Griffiths.;R D Situnayake.;B Clark.;A Tennant.;M Salmon.;P Emery.
来源: Rheumatology (Oxford). 2000年39卷8期857-64页
There are a significant number of patients with rheumatoid arthritis (RA) of North Indian or Pakistani origin (Asian) now living in the UK. RA has been poorly studied in this racial group. The aim of this study was to compare RA in this Asian group with RA in the indigenous northern European (European) population. It was hypothesized that these two racial groups would have different disease expressions and immunogenetics that could be relevant to pathogenesis, prognosis and therapy.
745. A randomized controlled trial comparing topical piroxicam gel with a homeopathic gel in osteoarthritis of the knee.
: To evaluate the efficacy and safety of a homeopathic gel vs an NSAID (piroxicam) gel in the treatment of osteoarthritis of the knee.
746. A comparison of the efficacy and safety of leflunomide and methotrexate for the treatment of rheumatoid arthritis.
作者: P Emery.;F C Breedveld.;E M Lemmel.;J P Kaltwasser.;P T Dawes.;B Gömör.;F Van Den Bosch.;D Nordström.;O Bjorneboe.;R Dahl.;K Horslev-Petersen.;A Rodriguez De La Serna.;M Molloy.;M Tikly.;C Oed.;R Rosenburg.;I Loew-Friedrich.
来源: Rheumatology (Oxford). 2000年39卷6期655-65页
To compare the clinical efficacy and safety of leflunomide and methotrexate for the treatment of rheumatoid arthritis (RA).
747. Preliminary investigation of debridement of plantar callosities in rheumatoid arthritis.
To determine the effect of expert debridement of foot callosities on forefoot pain and plantar pressure distribution in rheumatoid arthritis (RA).
748. Enhanced production of tissue inhibitor of metalloproteinases by peripheral blood mononuclear cells of rheumatoid arthritis patients responding to methotrexate treatment.
To determine the effects of methotrexate (MTX) treatment of rheumatoid arthritis (RA) patients (a) on the circulating levels and (b) on the ex vivo production of matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinases-1 (TIMP-1) by peripheral blood mononuclear cells (PBMNC).
749. Acute effects of etidronate on glucocorticoid-induced bone degradation.
作者: A Struijs.;A Smals.;S A de Witte.;W H Hackeng.;H Mulder.
来源: Rheumatology (Oxford). 2000年39卷5期523-9页
To study the acute short-term effects on the biochemical parameters of calcium and bone homeostasis in post-menopausal women treated with a high dose of prednisone alone or with additional etidronate, before and during 5 days of treatment.
750. An observer-blinded comparison of supervised and unsupervised aerobic exercise regimens in fibromyalgia.
作者: C Ramsay.;J Moreland.;M Ho.;S Joyce.;S Walker.;T Pullar.
来源: Rheumatology (Oxford). 2000年39卷5期501-5页
To compare a supervised 12-week aerobic exercise class with unsupervised home aerobic exercises in the treatment of patients with fibromyalgia.
751. Does waiting matter? A randomized controlled trial of new non-urgent rheumatology out-patient referrals.
作者: N P Hurst.;C M Lambert.;J Forbes.;A Lochhead.;K Major.;P Lock.
来源: Rheumatology (Oxford). 2000年39卷4期369-76页
To examine the effect of waiting times on the health status of patients referred for a non-urgent rheumatology opinion.
752. A clinical study of CPH 82 vs methotrexate in early rheumatoid arthritis.
The objectives of this study were to evaluate the therapeutic efficacy of CPH 82 in comparison with methotrexate (MTX) in adult patients with early, active rheumatoid arthritis (RA) and to compare the tolerance and safety profiles of the two drugs.
753. Effects of creatine supplementation on muscle weakness in patients with rheumatoid arthritis.
作者: B Willer.;G Stucki.;H Hoppeler.;P Brühlmann.;S Krähenbühl.
来源: Rheumatology (Oxford). 2000年39卷3期293-8页
Patients with rheumatoid arthritis (RA) frequently suffer from muscle weakness. Oral administration of creatine has been shown to improve muscle strength in healthy subjects. The objective of this study was to examine the effect of oral creatine supplementation on muscle weakness, disease activity and activities of daily living in patients with RA.
754. Evaluation of filtration leucocytapheresis for use in the treatment of patients with rheumatoid arthritis.
作者: Y Ueki.;S Yamasaki.;Y Kanamoto.;T Kawazu.;M Yano.;K Matsumoto.;S Miyake.;Y Tominaga.;U Iwamoto.;J Suemitsu.;Y Matsuno.;Y Sizume.;Y Takenaka.;K Eguchi.
来源: Rheumatology (Oxford). 2000年39卷2期165-71页
To evaluate the efficacy of filtration leucocytapheresis (LCP) for rheumatoid arthritis (RA).
755. Microemulsion formulation of cyclosporin (Sandimmun Neoral) vs Sandimmun: comparative safety, tolerability and efficacy in severe active rheumatoid arthritis. On behalf of the OLR 302 Study Group.
作者: D E Yocum.;S Allard.;S B Cohen.;P Emery.;R M Flipo.;J Goobar.;S Jayawardena.;C Job-Deslandre.;R W Jubb.;K Krüger.;A Lopes Vaz.;B Manger.;E Mur.;H Nygaard.;S M Weiner.;F Rainer.;M R Sack.;M H Schiff.;T J Schnitzer.;L B Trigg.;I Whatmough.;A G Schmidt.
来源: Rheumatology (Oxford). 2000年39卷2期156-64页
To compare the safety, tolerability and efficacy of the new oral microemulsion formulation of cyclosporin A (CyA; Sandimmun Neoral) and the original CyA formulation (Sandimmun), in patients with severe active rheumatoid arthritis (RA), over a 12-month period.
756. A preliminary study determining the feasibility of electromagnetic tracking for kinematics at the ankle joint complex.
To determine the feasibility of using electromagnetic tracking (EMT) for quantifying three-dimensional kinematics at the ankle joint complex (AJC).
757. A randomized, double-blind, placebo-controlled trial of sclerosing injections in patients with chronic low back pain.
To determine the clinical efficacy of sclerosing injections in patients with chronic low back pain.
758. Osteopenia in young hypogonadal women with systemic lupus erythematosus receiving chronic steroid therapy: a randomized controlled trial comparing calcitriol and hormonal replacement therapy.
作者: A W Kung.;T M Chan.;C S Lau.;R W Wong.;S S Yeung.
来源: Rheumatology (Oxford). 1999年38卷12期1239-44页
To evaluate the efficacy of calcitriol and hormonal replacement therapy (HRT) in the treatment of steroid-induced osteoporosis in hypogonadal women.
760. Effect of methotrexate on blood purine and pyrimidine levels in patients with rheumatoid arthritis.
作者: Z Smoleńska.;Z Kaznowska.;D Zarówny.;H A Simmonds.;R T Smoleński.
来源: Rheumatology (Oxford). 1999年38卷10期997-1002页
The mechanism of anti-inflammatory effects of methotrexate (MTX) at low dose may relate to a decrease in availability of the purine precursor or it may depend on accumulation of 5-aminoimidazole-4-carboxamide (AICAR) and the anti-inflammatory nucleoside adenosine. The aim of this study was to evaluate the possible mechanism of action by analysis of changes in blood concentrations of purine and pyrimidine metabolites during MTX treatment.
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