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701. Efficacy of inhaled steroids in undiagnosed subjects at high risk for COPD: results of the detection, intervention, and monitoring of COPD and asthma program.
作者: Mieke Albers.;Tjard Schermer.;Guido van den Boom.;Reinier Akkermans.;Constant van Schayck.;Cees van Herwaarden.;Chris van Weel.
来源: Chest. 2004年126卷6期1815-24页
COPD leads to a progressive decline of pulmonary function. Family physicians treat a substantial number of patients with COPD and are encouraged to start treatment at as early a stage as is possible. This study analyzed the effectiveness of early inhaled corticosteroid treatment on the decline of pulmonary function in COPD patients.
702. The importance of intrapericardial drain selection in cardiac surgery.
作者: Turan Ege.;Ersan Tatli.;Suat Canbaz.;Mustafa Cikirikcioglu.;Hasan Sunar.;Bilhan Ozalp.;Enver Duran.
来源: Chest. 2004年126卷5期1559-62页
To explore the impact of intrapericardial and infracardiac drains on pericardial effusions in cardiac surgery.
703. Supplemental oxygen impairs detection of hypoventilation by pulse oximetry.
作者: Eugene S Fu.;John B Downs.;John W Schweiger.;Rafael V Miguel.;Robert A Smith.
来源: Chest. 2004年126卷5期1552-8页
This two-part study was designed to determine the effect of supplemental oxygen on the detection of hypoventilation, evidenced by a decline in oxygen saturation (Spo(2)) with pulse oximetry.
704. Zafirlukast treatment for acute asthma: evaluation in a randomized, double-blind, multicenter trial.
作者: Robert A Silverman.;Richard M Nowak.;Phillip E Korenblat.;Emil Skobeloff.;Yusong Chen.;Catherine M Bonuccelli.;Christopher J Miller.;Steven G Simonson.
来源: Chest. 2004年126卷5期1480-9页
Acute asthma causes nearly 2 million hospital emergency department (ED) visits in the United States annually, and hospitalization after an ED visit and relapse after ED discharge are common.
705. A prospective randomized comparison of train-of-four monitoring and clinical assessment during continuous ICU cisatracurium paralysis.
作者: Michael H Baumann.;B Wayne McAlpin.;Keith Brown.;Praful Patel.;Imtiaz Ahmad.;Robert Stewart.;Marcy Petrini.
来源: Chest. 2004年126卷4期1267-73页
Train-of-four (TOF) monitoring is often recommended during the continuous use of neuromuscular blockade (NMB) [paralysis] in the ICU. Prior study results are conflicting regarding the benefits of TOF monitoring.
706. Impact of evacuated collection tube fill volume and mixing on routine coagulation testing using 2.5-ml (pediatric) tubes.
Anecdotal observations by pharmacists monitoring anticoagulated patients indicate that blood samples collected in 2.7-mL (pediatric) evacuated tubes frequently produced falsely elevated international normalized ratio (INR) results.
707. Strength vs aerobic training in children with cystic fibrosis: a randomized controlled trial.
作者: David M Orenstein.;Melbourne F Hovell.;Mary Mulvihill.;Kristen K Keating.;C Richard Hofstetter.;Sheryl Kelsey.;Kimberly Morris.;Patricia A Nixon.
来源: Chest. 2004年126卷4期1204-14页
Exercise has the potential to improve the ability of a patient with cystic fibrosis (CF) to cope with the physical demands of everyday life, and may improve prognosis. The purpose of this study was to compare the effects of a home-based, semi-supervised, upper-body strength-training regimen with a similarly structured aerobic training regimen.
708. Skin manifestations of inhaled corticosteroids in COPD patients: results from Lung Health Study II.
作者: Donald P Tashkin.;H Eileen Murray.;Melissa Skeans.;Robert P Murray.
来源: Chest. 2004年126卷4期1123-33页
To define the relationship between skin bruising (as well as other cutaneous manifestations) and inhaled corticosteroid (ICS) therapy vs placebo in subjects with COPD who were participating in a clinical trial. To explore the relationship between easy skin bruising and other systemic effects of ICS therapy, including adrenal suppression and loss of bone mineral density (BMD).
709. Mechanisms of improvement in exercise capacity using a rollator in patients with COPD.
作者: Vanessa S Probst.;Thierry Troosters.;Iris Coosemans.;Martijn A Spruit.;Fabio de Oliveira Pitta.;Marc Decramer.;Rik Gosselink.
来源: Chest. 2004年126卷4期1102-7页
We analyzed the effects of the use of a rollator on walking distance and physiologic variables: pulmonary gas exchange, heart rate, minute ventilation (Ve), oxygen saturation, and symptoms during the 6-min walk test (6MWT) in patients with COPD.
710. Daily oral care and cough reflex sensitivity in elderly nursing home patients.
作者: Aya Watando.;Satoru Ebihara.;Takae Ebihara.;Tatsuma Okazaki.;Hidenori Takahashi.;Masanori Asada.;Hidetada Sasaki.
来源: Chest. 2004年126卷4期1066-70页
Intensive oral care can reduce the incidence of pneumonia in elderly nursing home patients, but the mechanism is unknown.
711. Exercise training improves overall physical fitness and quality of life in older women with coronary artery disease.
作者: Chihya Hung.;Bill Daub.;Bill Black.;Robert Welsh.;Arthur Quinney.;Mark Haykowsky.
来源: Chest. 2004年126卷4期1026-31页
Older women with coronary artery disease (CAD) have reduced peak aerobic power (Vo(2)peak), muscle strength, and quality of life (QOL). Exercise interventions that can improve Vo(2)peak and muscle strength may also result in an improvement in QOL. This study compared the effect of aerobic training (AT) or combined aerobic and strength training (COMT) on Vo(2)peak, distance walked in 6 min, upper- and lower-extremity maximal strength, and QOL in 18 women (age range, 60 to 80 years) with documented CAD.
712. Efficacy and safety of a monoclonal antibody recognizing interleukin-8 in COPD: a pilot study.
To investigate the efficacy and safety of a fully human monoclonal antibody recognizing the chemokine interleukin (IL)-8 in patients with COPD.
713. Gastric vs small-bowel feeding in critically ill children receiving mechanical ventilation: a randomized controlled trial.
To determine the effect of feeding tube position (gastric vs small bowel) on adequacy of nutrient delivery and feeding complications, including microaspiration, in critically ill children.
714. Experimental human endotoxemia is associated with depression of load-independent contractility indices: prevention by the lipid a analogue E5531.
作者: Anand Kumar.;Eugene Bunnell.;Melvyn Lynn.;Ramon Anel.;Kalim Habet.;Alex Neumann.;Joseph E Parrillo.
来源: Chest. 2004年126卷3期860-7页
To evaluate the efficacy of a novel lipopolysaccharide (LPS) antagonist, E5531, in blocking LPS-induced cardiac responses including myocardial depression (as assessed by relatively load-independent echocardiographic indices of contractility) in a human model of experimental endotoxemia.
715. Assessment of physiologic variables and subjective comfort under different levels of pressure support ventilation.
作者: Michele Vitacca.;Luca Bianchi.;Ercole Zanotti.;Andrea Vianello.;Luca Barbano.;Roberto Porta.;Enrico Clini.
来源: Chest. 2004年126卷3期851-9页
To evaluate the effects of 12 ventilator settings (pressure support ventilation [PSV] plus positive end-expiratory pressure [PEEP], 30 + 0 cm H(2)O; 25 + 5 cm H(2)O; 25 + 0 cm H(2)O; 20 + 5 cm H(2)O; 20 + 0 cm H(2)O; 15 + 5 cm H(2)O; 15 + 0 cm H(2)O; 10 + 5 cm H(2)O; 10 + 0 cm H(2)O; 5 + 5 cm H(2)O; 5 + 0 cm H(2)O; and 0 + 5 cm H(2)O) on physiologic variables; the percentage of ineffective efforts; patient comfort; and whether the diagnosis of COPD may influence results.
716. Measurement of health-related quality of life in the national emphysema treatment trial.
To evaluate two generic and two disease-specific measures of health-related quality of life (QOL) using prerandomization data from the National Emphysema Treatment Trial (NETT).
717. Giving IV and oral amiodarone perioperatively for the prevention of postoperative atrial fibrillation in patients undergoing coronary artery bypass surgery: the GAP study.
作者: Joshua Kerstein.;Ajay Soodan.;Mehdi Qamar.;Mazhar Majid.;Edgar Lichstein.;Gerald Hollander.;Jacob Shani.
来源: Chest. 2004年126卷3期716-24页
We studied the use of perioperative IV and oral administration of amiodarone for the prevention of postoperative atrial fibrillation in patients undergoing coronary artery bypass graft surgery (CABG).
718. Superiority of fondaparinux over enoxaparin in preventing venous thromboembolism in major orthopedic surgery using different efficacy end points.
作者: Alexander G G Turpie.;Kenneth A Bauer.;Bengt I Eriksson.;Michael R Lassen.
来源: Chest. 2004年126卷2期501-8页
To assess the relevance of various efficacy end points established for thromboprophylaxis trials, we compared the results of the fondaparinux phase III program in major orthopedic surgery using the original primary efficacy end point with those obtained when the efficacy end points recently suggested by the American College of Chest Physicians (ACCP) Consensus Conference on Antithrombotic Therapy and the European Committee for Proprietary Medicinal Products (CPMP) were used.
719. Quality of life after coronary artery bypass graft: results from the POST CABG Trial.
作者: Norma Lynn Fox.;Byron J Hoogwerf.;Susan Czajkowski.;Ruth Lindquist.;Gilles Dupuis.;J Alan Herd.;Lucien Campeau.;Ann Hickey.;Franca B Barton.;Michael L Terrin.; .
来源: Chest. 2004年126卷2期487-95页
The POST CABG (Post Coronary Artery Bypass Graft) Trial showed that aggressive lowering of low-density lipoprotein (LDL) cholesterol levels reduced the progression of atherosclerosis in saphenous vein grafts. In the extended follow-up phase, aggressive lowering of LDL cholesterol levels was associated with reduced rates of clinical events. Low-dose anticoagulation therapy did not reduce the progression of atherosclerosis. We conducted this analysis to determine the effects of both lipid-lowering and low-dose anticoagulation therapy on health-related quality of life (HRQL).
720. Rate control vs rhythm control in patients with nonvalvular persistent atrial fibrillation: the results of the Polish How to Treat Chronic Atrial Fibrillation (HOT CAFE) Study.
作者: Grzegorz Opolski.;Adam Torbicki.;Dariusz A Kosior.;Marcin Szulc.;Beata Wozakowska-Kaplon.;Piotr Kolodziej.;Piotr Achremczyk.; .
来源: Chest. 2004年126卷2期476-86页
The relative risks and benefits of strategies of rate control vs rhythm control in patients with atrial fibrillation (AF) remain to be fully explored.
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