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共有 806 条符合本次的查询结果, 用时 3.5185776 秒

621. Triamcinolone acetonide and hexacetonide intra-articular treatment of symmetrical joints in juvenile idiopathic arthritis: a double-blind trial.

作者: F Zulian.;G Martini.;D Gobber.;M Plebani.;F Zacchello.;P Manners.
来源: Rheumatology (Oxford). 2004年43卷10期1288-91页
Pharmacokinetic studies have shown that the biological effect of triamcinolone acetonide (TA) is equivalent to that of triamcinolone hexacetonide (TH), if used at double the dosage. In this study we compared the efficacy of intra-articular TA at a dose twice that of TH in symmetrically involved joints, in children with juvenile idiopathic arthritis (JIA).

622. The burden of ankylosing spondylitis and the cost-effectiveness of treatment with infliximab (Remicade).

作者: G Kobelt.;P Andlin-Sobocki.;S Brophy.;L Jönsson.;A Calin.;J Braun.
来源: Rheumatology (Oxford). 2004年43卷9期1158-66页
In the past, treatment options for ankylosing spondylitis (AS) have been limited, and the introduction of new treatments such as infliximab will have a noticeable impact on health-care budgets. The objective of this study was therefore to assess the current burden of the disease and estimate the cost-effectiveness of infliximab treatments.

623. Supplementing a home exercise programme with a class-based exercise programme is more effective than home exercise alone in the treatment of knee osteoarthritis.

作者: C J McCarthy.;P M Mills.;R Pullen.;C Roberts.;A Silman.;J A Oldham.
来源: Rheumatology (Oxford). 2004年43卷7期880-6页
The study aimed to compare the relative effectiveness of providing a home-based exercise programme versus home-based exercise supplemented with an 8-week class-based exercise programme in reducing pain and improving function in patients with knee osteoarthritis.

624. Intra-articular methotrexate in knee synovitis.

作者: N Hasso.;P J Maddison.;A Breslin.
来源: Rheumatology (Oxford). 2004年43卷6期779-82页
To test whether methotrexate prolongs the effect of intra-articular corticosteroid in suppressing knee synovitis.

625. Patient-reported outcomes better discriminate active treatment from placebo in randomized controlled trials in rheumatoid arthritis.

作者: V Strand.;S Cohen.;B Crawford.;J S Smolen.;D L Scott.; .
来源: Rheumatology (Oxford). 2004年43卷5期640-7页
Recent randomized controlled trials (RCTs) in rheumatoid arthritis (RA) have used patient- and physician-reported outcomes, ESR and/or CRP as components of ACR response criteria to assess efficacy.

626. Efficacy and safety of leflunomide 10 mg versus 20 mg once daily in patients with active rheumatoid arthritis: multinational double-blind, randomized trial.

作者: G Poór.;V Strand.; .
来源: Rheumatology (Oxford). 2004年43卷6期744-9页
To compare the efficacy and safety profile of two daily maintenance doses of leflunomide, 10 mg and 20 mg, for the treatment of active rheumatoid arthritis (RA).

627. SAPHO syndrome treated with pamidronate: an open-label study of 10 patients.

作者: H Amital.;Y H Applbaum.;S Aamar.;N Daniel.;A Rubinow.
来源: Rheumatology (Oxford). 2004年43卷5期658-61页
In recent years the SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis and osteitis) has been encountered more frequently. However, clinical evidence indicating superiority of a specific therapeutic modality is still absent. Pamidronate, a second-generation bisphosphonate, has a pronounced effect on bone metabolism by suppressing bone resorption. We report our clinical experience with intravenous pamidronate in SAPHO syndrome.

628. How aggressive should initial therapy for rheumatoid arthritis be? Factors associated with response to 'non-aggressive' DMARD treatment and perspective from a 2-yr open label trial.

作者: E L Matteson.;C M Weyand.;J W Fulbright.;T J H Christianson.;R L McClelland.;J J Goronzy.
来源: Rheumatology (Oxford). 2004年43卷5期619-25页
To determine what baseline factors might be associated with response to an initial mild treatment regimen in patients with early rheumatoid arthritis (RA).

629. Lupus nephritis: treatment with mycophenolate mofetil.

作者: P P Kapitsinou.;J N Boletis.;F N Skopouli.;K A Boki.;H M Moutsopoulos.
来源: Rheumatology (Oxford). 2004年43卷3期377-80页
To evaluate the safety and efficacy of mycophenolate mofetil (MMF) treatment in patients with lupus nephritis.

630. Maintenance of remission with leflunomide in Wegener's granulomatosis.

作者: C Metzler.;C Fink.;P Lamprecht.;W L Gross.;E Reinhold-Keller.
来源: Rheumatology (Oxford). 2004年43卷3期315-20页
To investigate the safety and efficacy of leflunomide plus low-dose prednisolone for the maintenance of remission in Wegener's granulomatosis (WG).

631. Celecoxib 200 mg q.d. is efficacious in the management of osteoarthritis of the knee or hip regardless of the time of dosing.

作者: K Stengaard-Pedersen.;R Ekesbo.;A-L Karvonen.;M Lyster.
来源: Rheumatology (Oxford). 2004年43卷5期592-5页
The primary objective was to demonstrate equivalence between a.m. and p.m. dosing of celecoxib 200 mg q.d. An equivalence assessment of q.d. vs b.i.d. dosing was a secondary objective.

632. Improved clinical status in fibromyalgia patients treated with individualized homeopathic remedies versus placebo.

作者: I R Bell.;D A Lewis.;A J Brooks.;G E Schwartz.;S E Lewis.;B T Walsh.;C M Baldwin.
来源: Rheumatology (Oxford). 2004年43卷5期577-82页
To assess the efficacy of individualized classical homeopathy in the treatment of fibromyalgia.

633. The reliability, validity and responsiveness of an aggregated locomotor function (ALF) score in patients with osteoarthritis of the knee.

作者: C J McCarthy.;J A Oldham.
来源: Rheumatology (Oxford). 2004年43卷4期514-7页
The aggregated locomotor function (ALF) score, a simple measure of observed locomotor function, using timed walking, stairs and transfers, was developed and evaluated for intra-tester reliability, criterion-related validity and responsiveness in a sample of patients with knee osteoarthritis.

634. The health assessment questionnaire (HAQ) is strongly predictive of good outcome in early diffuse scleroderma: results from an analysis of two randomized controlled trials in early diffuse scleroderma.

作者: N Sultan.;J E Pope.;P J Clements.; .
来源: Rheumatology (Oxford). 2004年43卷4期472-8页
Scoring poorly on the health assessment questionnaire (HAQ) has recently been shown to be a strong predictor of morbidity and mortality in rheumatoid arthritis (RA), while a good HAQ score is predictive of a better outcome. In patients presenting with early diffuse scleroderma prognosis is variable. Our goal was to determine possible baseline predictors of future good outcomes.

635. Economic evaluation of oral valdecoxib versus diclofenac in the treatment of patients with rheumatoid arthritis in a randomized clinical trial.

作者: B von Scheele.;B Peña.;J Wong.;L Niculescu.
来源: Rheumatology (Oxford). 2003年42 Suppl 3卷iii53-9页
In contrast to economic models that provide probabilistic estimates of economic impact, data extracted from clinical trials may be used to evaluate and compare actual resource utilization and costs. Health-care resource utilization and the costs of these resources were compared from the perspective of the UK National Health Service using data obtained in a 6-month clinical trial of oral valdecoxib 20 mg once daily and diclofenac 75 mg twice daily for the symptomatic treatment of rheumatoid arthritis. However, calculated health-care costs were exclusive of drug acquisition costs because the price of valdecoxib was not available at the time of analysis. While the efficacy of the two treatments was similar, use of valdecoxib was associated with a reduction in total health-care costs amounting to approximately 200 British pounds per patient. This lower cost was associated with reduced use of health-care resources for gastrointestinal serious adverse events (gastrointestinal SAEs). In particular, the incidence of hospitalization and number of hospital days for gastrointestinal SAEs was lower in the valdecoxib group. Analysis of cost per gastrointestinal SAE favoured valdecoxib (cost savings of 742 British pounds), suggesting that even when these events did occur they were less severe. When costs of gastrointestinal SAEs were averaged over the entire population, valdecoxib was suggested to have lower total costs per patient compared with diclofenac (cost savings of 115 British pounds per patient), mainly resulting from significant savings in hospitalization costs (76.49 British pounds per patient). These data are consistent with economic models and suggest that the favourable gastrointestinal profile of valdecoxib observed in clinical trials will be of economic benefit.

636. Does the application of tape influence quadriceps sensorimotor function in knee osteoarthritis?

作者: R S Hinman.;K M Crossley.;J McConnell.;K L Bennell.
来源: Rheumatology (Oxford). 2004年43卷3期331-6页
Using additional data from two previously reported studies, the aim was to determine the effects of immediate and short-term continuous (3 weeks) application of knee tape on quadriceps sensorimotor function in individuals with symptomatic knee osteoarthritis (OA).

637. Re: Karlsson et al. Comparison of two hyaluronan drugs and placebo in patients with knee osteoarthritis. A controlled, randomized, double-blind, parallel-design multicentre study.

作者: D Magilavy.;R Polisson.;D Parenti.
来源: Rheumatology (Oxford). 2003年42卷10期1262; author reply 1262-3页

638. Remission induction in Behçet's disease following lymphocyte depletion by the anti-CD52 antibody CAMPATH 1-H.

作者: C M Lockwood.;G Hale.;H Waldman.;D R W Jayne.
来源: Rheumatology (Oxford). 2003年42卷12期1539-44页
Behçet's disease (BD) is a multisystem vasculopathy of unknown cause with variable clinical presentation and the outcome of current treatments is often unsatisfactory. There is evidence for T-cell autoreactivity in BD and this study explores the therapeutic response to lymphocyte depletion with a humanized anti-CD52 antibody, CAMPATH-1H.

639. Effect of bisphosphonate treatment in patients with Paget's disease of the skull.

作者: J Donáth.;M Krasznai.;B Fornet.;P Gergely.;G Poór.
来源: Rheumatology (Oxford). 2004年43卷1期89-94页
Hearing loss has long been known to be a complication of Paget's disease of bone. The aim of this study was to investigate Paget's disease of the temporal bone with special attention to hearing loss.

640. Acupuncture for chronic low back pain in older patients: a randomized, controlled trial.

作者: C F Meng.;D Wang.;J Ngeow.;L Lao.;M Peterson.;S Paget.
来源: Rheumatology (Oxford). 2003年42卷12期1508-17页
To determine if acupuncture is an effective, safe adjunctive treatment to standard therapy for chronic low back pain (LBP) in older patients.
共有 806 条符合本次的查询结果, 用时 3.5185776 秒