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581. Allergic rhinitis and sinusitis in asthma: differential effects on symptoms and pulmonary function.
作者: Anne E Dixon.;David A Kaminsky.;Janet T Holbrook.;Robert A Wise.;David M Shade.;Charles G Irvin.
来源: Chest. 2006年130卷2期429-35页
Allergic rhinitis and sinusitis are frequently associated with asthma. The purpose of this study was to determine the impact of self-reported allergic rhinitis and sinusitis on lower airway disease in a large cohort of participants with well-characterized asthma.
582. Nurse-conducted smoking cessation in patients with COPD using nicotine sublingual tablets and behavioral support.
Few studies have examined the effect of nicotine replacement therapy (NRT) in COPD patients.
583. Effects of continuous positive airway pressure on pulmonary function and exercise tolerance in patients with congestive heart failure.
作者: Veronica L Wittmer.;Giovana M S Simoes.;Luciana C M Sogame.;Elisardo C Vasquez.
来源: Chest. 2006年130卷1期157-63页
Continuous positive airway pressure (CPAP) has been used to improve cardiopulmonary function and reduce pulmonary edema symptoms in patients with congestive heart failure (CHF). The objective of this study was to evaluate the efficacy of CPAP therapy on pulmonary function and exercise tolerance in patients with CHF.
584. Angiotensin-converting enzyme inhibitors slow recovery from anemia following cardiac surgery.
作者: Vittorino Ripamonti.;Vittorio Racca.;Maria G Calvo.;Paolo Castiglioni.;Maurizio Ferratini.
来源: Chest. 2006年130卷1期79-84页
Angiotensin-converting enzyme (ACE) inhibitors, which are frequently administered in patients with heart disease, have a known inhibitory effect on erythropoiesis. The aim of this study was to detect whether early ACE inhibitor administration slows recovery from anemia following recent cardiac surgery.
585. Improvement in bronchodilation following deep inspiration after a course of high-dose oral prednisone in asthma.
作者: Annelies M Slats.;Jacob K Sont.;Rik H C J van Klink.;Elisabeth H D Bel.;Peter J Sterk.
来源: Chest. 2006年130卷1期58-65页
Bronchodilation following deep inspiration is usually impaired in patients with asthma. This might be due to changes in airway mechanics in the presence of inflammation or structural changes within the airways. Although inhaled corticosteroid treatment has been shown to improve airway responses to deep inspiration in patients with asthma, airway inflammation can persist despite inhaled corticosteroid treatment, and thus could still influence the airway mechanics during deep breaths. We hypothesized that oral steroid treatment further optimizes deep inspiration-induced bronchodilation in clinically stable asthmatic patients who are receiving therapy with inhaled corticosteroids.
586. A randomized controlled trial of follow-up of patients discharged from the hospital following acute asthma: best performed by specialist nurse or doctor?
作者: James A Nathan.;Linda Pearce.;Carol Field.;Nina Dotesio-Eyres.;Linda D Sharples.;Fay Cafferty.;Clare M Laroche.
来源: Chest. 2006年130卷1期51-7页
To evaluate whether follow-up of patients recently discharged from the hospital as a result of acute asthma can be adequately provided by a respiratory specialist nurse compared to a respiratory doctor.
587. Improvement in quadriceps strength and dyspnea in daily tasks after 1 month of electrical stimulation in severely deconditioned and malnourished COPD.
作者: Isabelle Vivodtzev.;Jean-Louis Pépin.;Gabrielle Vottero.;Valerie Mayer.;Bernard Porsin.;Patrick Lévy.;Bernard Wuyam.
来源: Chest. 2006年129卷6期1540-8页
Low body weight in COPD patients is associated with worsening dyspnea, reduced leg strength, and poor prognosis. Classical rehabilitation strategies are then limited by reduced exercise tolerance. Thus, we proposed to evaluate whether electrostimulation (ES) was a beneficial technique in the rehabilitation programs for severely deconditioned COPD patients after an acute exacerbation.
588. Effects of early intervention with inhaled budesonide on lung function in newly diagnosed asthma.
作者: Paul M O'Byrne.;Søren Pedersen.;William W Busse.;Wan C Tan.;Yu-Zhi Chen.;Stefan V Ohlsson.;Anders Ullman.;Carl Johan Lamm.;Romain A Pauwels.; .
来源: Chest. 2006年129卷6期1478-85页
Asthmatic patients lose lung function faster than normal subjects. The effectiveness of early intervention with inhaled corticosteroids on this decline in lung function is not established in recent-onset disease.
589. Effect of continuous positive airway pressure on ambulatory BP in patients with sleep apnea and hypertension: a placebo-controlled trial.
作者: Francisco Campos-Rodriguez.;Antonio Grilo-Reina.;Jose Perez-Ronchel.;Mercedes Merino-Sanchez.;Maria A Gonzalez-Benitez.;Manuel Beltran-Robles.;Carmen Almeida-Gonzalez.
来源: Chest. 2006年129卷6期1459-67页
Obstructive sleep apnea syndrome (OSAS) is an independent risk factor for arterial hypertension. Several controlled trials have investigated the effect of continuous positive airway pressure (CPAP) on BP in patients with OSAS, but its effect on hypertensive patients has not been analyzed specifically.
590. Achieving housestaff competence in emergency airway management using scenario based simulation training: comparison of attending vs housestaff trainers.
作者: Marnie E Rosenthal.;Mari Adachi.;Vanessa Ribaudo.;J Tristan Mueck.;Roslyn F Schneider.;Paul H Mayo.
来源: Chest. 2006年129卷6期1453-8页
To evaluate a teaching protocol comparing a critical care attending to a housestaff team in training medical interns in initial airway management skills using a computer-controlled patient simulator (CPS) and scenario-based simulation training (SST).
591. Acute relief of exercise-induced bronchoconstriction by inhaled formoterol in children with persistent asthma.
作者: Mette Northman Hermansen.;Kim Gjerum Nielsen.;Frederik Buchvald.;Jakob Jessing Jespersen.;Thomas Bengtsson.;Hans Bisgaard.
来源: Chest. 2006年129卷5期1203-9页
To compare the acute bronchodilatory effect of the long-acting beta2-agonist formoterol against the short-acting beta2-agonist (SABA) terbutaline during exercise-induced bronchoconstriction (EIB) in children with asthma.
592. Efficacy of a heat exchanger mask in cold exercise-induced asthma.
To determine the efficacy of a novel mask device in limiting cold air exercise-induced decline in lung function in subjects with a history of exercise-induced asthma (EIA).
593. Ciclesonide reduces the need for oral steroid use in adult patients with severe, persistent asthma.
作者: Eric Bateman.;Jill Karpel.;Thomas Casale.;Sally Wenzel.;Donald Banerji.
来源: Chest. 2006年129卷5期1176-87页
Oral corticosteroids (OCS) may be associated with systemic adverse events (AEs), which can be reduced by replacing OCS with inhaled corticosteroids (ICS). The potential of ciclesonide, a novel ICS, to reduce OCS use in patients with severe, persistent asthma was evaluated in this study.
594. A randomized trial of different docetaxel schedules in non-small cell lung cancer patients who failed previous platinum-based chemotherapy.
作者: Yuh-Min Chen.;Jen-Fu Shih.;Reury-Perng Perng.;Chun-Ming Tsai.;Jacqueline Whang-Peng.
来源: Chest. 2006年129卷4期1031-8页
Docetaxel has shown activity in the second-line treatment of non-small cell lung cancer (NSCLC). Phase II studies have suggested that weekly therapy with docetaxel probably has a better toxicity profile than the conventional schedule of once every 3 weeks. Our aim was to evaluate and compare the efficacy of different docetaxel schedules in NSCLC patients who did not respond to previous platinum-based chemotherapy.
595. Inhaled nitric oxide does not prevent pulmonary edema after lung transplantation measured by lung water content: a randomized clinical study.
作者: Gilles Perrin.;Antoine Roch.;Pierre Michelet.;Martine Reynaud-Gaubert.;Pascal Thomas.;Christophe Doddoli.;Jean-Pierre Auffray.
来源: Chest. 2006年129卷4期1024-30页
In order to assess the effects of inhaled nitric oxide (iNO) in preventing early-onset lung edema from occurring after lung transplantation, we measured extravascular lung water (EVLW) in a group of lung transplant recipients who were at high risk for developing ischemia-reperfusion-induced lung injury.
596. Impact of pulmonary rehabilitation on psychosocial morbidity in patients with severe COPD.
作者: Rosa Güell.;Vanesa Resqueti.;Mercedes Sangenis.;Fatima Morante.;Bernardi Martorell.;Pere Casan.;Gordon H Guyatt.
来源: Chest. 2006年129卷4期899-904页
To assess the effect of pulmonary rehabilitation (PR) on psychosocial morbidity, functional exercise capacity, and health-related quality of life (HRQL) in patients with severe COPD.
597. Airway blood flow reactivity in healthy smokers and in ex-smokers with or without COPD.
Cigarette smoking has been associated with impaired endothelium-dependent relaxation responses in the brachial and coronary arteries (endothelial dysfunction). The aim of the present study was to determine whether the airway circulation is also affected and whether pharmacologic treatment has an effect on endothelial function in patients with COPD.
598. Exercise performance improves in patients with COPD due to respiratory muscle endurance training.
作者: Ralph J H Koppers.;Petra J E Vos.;Cecile R L Boot.;Hans Th M Folgering.
来源: Chest. 2006年129卷4期886-92页
Impaired exercise tolerance is frequently observed in patients with COPD. Respiratory muscle endurance training (RMET) by means of normocapnic hyperpnea can be used to improve respiratory muscle function and probably exercise capacity. RMET is not applied on a large scale because complicated equipment is needed to maintain carbon dioxide homeostasis during hyperpnea, which can also be done by enlarging the dead space of the ventilatory system by breathing through a tube. Therefore, tube breathing might be a new, inexpensive method for home-based RMET. The aim of this study was to assess whether home-based RMET by means of tube breathing improves endurance exercise performance in patients with COPD.
599. A randomized controlled trial on office spirometry in asthma and COPD in standard general practice: data from spirometry in Asthma and COPD: a comparative evaluation Italian study.
作者: Mirco Lusuardi.;Fernando De Benedetto.;Pierluigi Paggiaro.;Claudio M Sanguinetti.;Giancarlo Brazzola.;Paolo Ferri.;Claudio F Donner.
来源: Chest. 2006年129卷4期844-52页
To evaluate whether office spirometry by general practitioners (GPs) is feasible and may improve the diagnosis of asthma and COPD.
600. Effect of high-frequency chest wall oscillation on the central and peripheral distribution of aerosolized diethylene triamine penta-acetic acid as compared to standard chest physiotherapy in cystic fibrosis.
作者: Steven W Stites.;Gayln V Perry.;Tom Peddicord.;Glen Cox.;Chris McMillan.;Brian Becker.
来源: Chest. 2006年129卷3期712-7页
High-frequency chest wall oscillation (HFCWO) has been shown to be as effective as standard chest physiotherapy (SCPT) for removal of pulmonary secretions as well as increasing FEV(1) in cystic fibrosis (CF) patients. Patients using HFCWO often administer aerosolized medications simultaneously, reducing time required for daily care. While peripheral pulmonary distribution of tracer in normal subjects has been shown to be unaffected by HFCWO, this has not been studied in CF patients. We evaluated distribution of aerosolized (99m)Tc diethylene triamine penta-acetic acid (DTPA) administered simultaneously with HFCWO and compared this with DTPA aerosolized after SCPT.
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