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521. Comparison of three active therapies for chronic low back pain: results of a randomized clinical trial with one-year follow-up.
To examine the relative efficacy of three active therapies for patients with chronic low back pain.
522. Effects of the American College of Rheumatology systemic sclerosis trial guidelines on the nature of systemic sclerosis patients entering a clinical trial.
作者: D E Furst.;P J Clements.;W K Wong.;M D Mayes.;F Wigley.;B White.;M Weisman.;W Barr.;L Moreland.;R Martin.;T A Medsger.;V Steen.;D Collier.;A Weinstein.;E Lally.;J Varga.;S R Weiner.;B Andrews.;M Abeles.;J B Peter.;J R Seibold.
来源: Rheumatology (Oxford). 2001年40卷6期615-22页
To compare the systemic sclerosis (SSc) patients entered into the d-penicillamine trial with SSc patients entered into previous controlled SSc trials. It was hypothesized that the d-penicillamine trial patients, who conformed to the American College of Rheumatology (ACR) guidelines for clinical trials in SSc were different from patients entered into previous trials.
523. Intravenous immunoglobulin application following immunoadsorption: benefit or risk in patients with autoimmune diseases?
作者: S Schmaldienst.;M Müllner.;A Goldammer.;S Spitzauer.;S Banyai.;W H Hörl.;K Derfler.
来源: Rheumatology (Oxford). 2001年40卷5期513-21页
To evaluate infection rates, side-effects and autoantibody resynthesis after immunoadsorption with and without intravenous immunoglobulin substitution.
524. The relationship between soft tissue swelling, joint space narrowing and erosive damage in hand X-rays of patients with rheumatoid arthritis.
To test the hypotheses that the progression of joint space narrowing behaves differently from the progression of erosions and that clinically and radiologically assessed soft tissue swelling relates more to diffuse cartilage loss than to erosive damage.
525. Morphological analysis of knee synovial membrane biopsies from a randomized controlled clinical study comparing the effects of sodium hyaluronate (Hyalgan) and methylprednisolone acetate (Depomedrol) in osteoarthritis.
作者: I Pasquali Ronchetti.;D Guerra.;F Taparelli.;F Boraldi.;G Bergamini.;G Mori.;F Zizzi.;L Frizziero.
来源: Rheumatology (Oxford). 2001年40卷2期158-69页
The study was part of a randomized open-label clinical trial designed to evaluate the effects of intra-articular injections of hyaluronan (Hyalgan) (HY) in osteoarthritis (OA) of the human knee. Data were compared with those obtained after treatment with methylprednisolone acetate (Depomedrol) (MP).
526. Are antineutrophil cytoplasmic antibodies a marker predictive of relapse in Wegener's granulomatosis? A prospective study.
作者: T Girard.;A Mahr.;L H Noël.;J F Cordier.;P Lesavre.;M H André.;L Guillevin.
来源: Rheumatology (Oxford). 2001年40卷2期147-51页
To investigate the predictive value of testing for antineutrophil cytoplasmic antibodies (ANCA) in 55 patients with systemic Wegener's granulomatosis (WG) included in a randomized, prospective trial comparing corticosteroids and oral or pulse cyclophosphamide.
527. The effects of treatment with interleukin-1 receptor antagonist on the inflamed synovial membrane in rheumatoid arthritis.
作者: G Cunnane.;A Madigan.;E Murphy.;O FitzGerald.;B Bresnihan.
来源: Rheumatology (Oxford). 2001年40卷1期62-9页
To evaluate the effects of treatment with interleukin-1 receptor antagonist (IL-1Ra) on synovial tissue in rheumatoid arthritis (RA).
528. Toxicity of anti-rheumatic drugs in a randomized clinical trial of early rheumatoid arthritis.
作者: C H van Jaarsveld.;Z N Jahangier.;J W Jacobs.;A A Blaauw.;G A van Albada-Kuipers.;E J ter Borg.;H L Brus.;Y Schenk.;M J van Der Veen.;J W Bijlsma.
来源: Rheumatology (Oxford). 2000年39卷12期1374-82页
To evaluate the toxicity of slow-acting anti-rheumatic drugs (SAARDs) and non-steroidal anti-inflammatory drugs (NSAIDs) in early rheumatoid arthritis.
529. Effect of SR 49059, a V1a vasopressin receptor antagonist, in Raynaud's phenomenon.
作者: D Hayoz.;G Bizzini.;B Noël.;M Depairon.;M Burnier.;C Fauveau.;A Rouillon.;R Brouard.;H R Brunner.
来源: Rheumatology (Oxford). 2000年39卷10期1132-8页
To assess whether vasopressin V1a receptor blockade reduces the abnormal vasoactive response to cold in patients suffering from Raynaud's phenomenon (RP).
530. Do patients with rheumatoid arthritis established on methotrexate and folic acid 5 mg daily need to continue folic acid supplements long term?
作者: S M Griffith.;J Fisher.;S Clarke.;B Montgomery.;P W Jones.;J Saklatvala.;P T Dawes.;M F Shadforth.;T E Hothersall.;A B Hassell.;E M Hay.
来源: Rheumatology (Oxford). 2000年39卷10期1102-9页
It is postulated that some aspects of methotrexate toxicity may be related to its action as an anti-folate. Folic acid (FA) is often given as an adjunct to methotrexate therapy, but there is no conclusive proof that it decreases the toxicity of methotrexate and there is a theoretical risk that it may decrease the efficacy of methotrexate.
531. The long-term effects of non-steroidal anti-inflammatory drugs in osteoarthritis of the knee: a randomized placebo-controlled trial.
作者: D L Scott.;H Berry.;H Capell.;J Coppock.;T Daymond.;D V Doyle.;L Fernandes.;B Hazleman.;J Hunter.;E C Huskisson.;A Jawad.;R Jubb.;T Kennedy.;P McGill.;F Nichol.;J Palit.;M Webley.;A Woolf.;J Wotjulewski.
来源: Rheumatology (Oxford). 2000年39卷10期1095-101页
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to treat osteoarthritis (OA), though their long-term efficacy is uncertain. We report a comparison of the symptomatic responses to therapy with tiaprofenic acid, indomethacin and placebo over 5 yr.
532. Remission and response to early treatment of RA assessed by the Disease Activity Score. BARFOT study group. Better Anti-rheumatic Farmacotherapy.
作者: B Svensson.;C Schaufelberger.;A Teleman.;J Theander.
来源: Rheumatology (Oxford). 2000年39卷9期1031-6页
To assess criteria for individual response and remission based on the Disease Activity Score (DAS) in patients with RA participating in a long-term observational study.
533. Reliability and sensitivity to change of various measures of hand function in relation to treatment of synovitis of the metacarpophalangeal joint in rheumatoid arthritis.
作者: P H Goossens.;B Heemskerk.;J van Tongeren.;A H Zwinderman.;T P Vliet Vlieland.;T W Huizinga.
来源: Rheumatology (Oxford). 2000年39卷8期909-13页
The reliability and discriminative capacity of hand function tests were studied in order to obtain tests suitable for the evaluation of local treatment of an arthritic metacarpophalangeal (MCP) joint.
534. Long-term efficacy of radon spa therapy in rheumatoid arthritis--a randomized, sham-controlled study and follow-up.
作者: A Franke.;L Reiner.;H G Pratzel.;T Franke.;K L Resch.
来源: Rheumatology (Oxford). 2000年39卷8期894-902页
To quantify the efficacy of a series of baths containing natural radon and carbon dioxide (1.3 kBq/l, 1.6 g carbon dioxide/l on average) versus artificial carbon dioxide baths alone in patients with rheumatoid arthritis.
535. A randomized controlled trial comparing topical piroxicam gel with a homeopathic gel in osteoarthritis of the knee.
: To evaluate the efficacy and safety of a homeopathic gel vs an NSAID (piroxicam) gel in the treatment of osteoarthritis of the knee.
536. A comparison of the efficacy and safety of leflunomide and methotrexate for the treatment of rheumatoid arthritis.
作者: P Emery.;F C Breedveld.;E M Lemmel.;J P Kaltwasser.;P T Dawes.;B Gömör.;F Van Den Bosch.;D Nordström.;O Bjorneboe.;R Dahl.;K Horslev-Petersen.;A Rodriguez De La Serna.;M Molloy.;M Tikly.;C Oed.;R Rosenburg.;I Loew-Friedrich.
来源: Rheumatology (Oxford). 2000年39卷6期655-65页
To compare the clinical efficacy and safety of leflunomide and methotrexate for the treatment of rheumatoid arthritis (RA).
537. Acute effects of etidronate on glucocorticoid-induced bone degradation.
作者: A Struijs.;A Smals.;S A de Witte.;W H Hackeng.;H Mulder.
来源: Rheumatology (Oxford). 2000年39卷5期523-9页
To study the acute short-term effects on the biochemical parameters of calcium and bone homeostasis in post-menopausal women treated with a high dose of prednisone alone or with additional etidronate, before and during 5 days of treatment.
538. An observer-blinded comparison of supervised and unsupervised aerobic exercise regimens in fibromyalgia.
作者: C Ramsay.;J Moreland.;M Ho.;S Joyce.;S Walker.;T Pullar.
来源: Rheumatology (Oxford). 2000年39卷5期501-5页
To compare a supervised 12-week aerobic exercise class with unsupervised home aerobic exercises in the treatment of patients with fibromyalgia.
539. Does waiting matter? A randomized controlled trial of new non-urgent rheumatology out-patient referrals.
作者: N P Hurst.;C M Lambert.;J Forbes.;A Lochhead.;K Major.;P Lock.
来源: Rheumatology (Oxford). 2000年39卷4期369-76页
To examine the effect of waiting times on the health status of patients referred for a non-urgent rheumatology opinion.
540. A clinical study of CPH 82 vs methotrexate in early rheumatoid arthritis.
The objectives of this study were to evaluate the therapeutic efficacy of CPH 82 in comparison with methotrexate (MTX) in adult patients with early, active rheumatoid arthritis (RA) and to compare the tolerance and safety profiles of the two drugs.
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