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481. Effects of anti-TNF-alpha antibody infliximab in refractory entero-Behcet's disease.
作者: Shigeru Iwata.;Kazuyoshi Saito.;Kunihiro Yamaoka.;Shizuyo Tsujimura.;Masao Nawata.;Katsunori Suzuki.;Yoshiya Tanaka.
来源: Rheumatology (Oxford). 2009年48卷8期1012-3页 482. Experience with rituximab in scleroderma: results from a 1-year, proof-of-principle study.
作者: Dimitrios Daoussis.;Stamatis-Nick C Liossis.;Athanassios C Tsamandas.;Christina Kalogeropoulou.;Alexandra Kazantzi.;Chaido Sirinian.;Maria Karampetsou.;Georgios Yiannopoulos.;Andrew P Andonopoulos.
来源: Rheumatology (Oxford). 2010年49卷2期271-80页
To assess the efficacy of rituximab (RTX) in SSc.
483. The decrease of soluble RAGE levels in rheumatoid arthritis patients following hormone replacement therapy is associated with increased bone mineral density and diminished bone/cartilage turnover: a randomized controlled trial.
作者: Rille Pullerits.;Helena Forsblad d'Elia.;Andrej Tarkowski.;Hans Carlsten.
来源: Rheumatology (Oxford). 2009年48卷7期785-90页
The aim of the study was to prospectively investigate the effects of HRT on serum soluble receptor for advanced glycation end product (sRAGE) levels in RA patients and to determine whether sRAGE production is related to bone/cartilage metabolism.
484. Intra-articular clodronate for the treatment of knee osteoarthritis: dose ranging study vs hyaluronic acid.
作者: Maurizio Rossini.;Ombretta Viapiana.;Roberta Ramonda.;Gerolamo Bianchi.;Ignazio Olivieri.;Giovanni Lapadula.;Silvano Adami.
来源: Rheumatology (Oxford). 2009年48卷7期773-8页
Bisphosphonates may have a chondroprotective effect in patients with knee OA (KOA), but the results of clinical trials with oral bisphosphonates have been contradictory. In this Phase 2 randomized, partially blind clinical trial, we tested the efficacy of IA clodronate vs HA in patients with primary KOA.
485. Do OA patients gain additional benefit from care from a clinical nurse specialist?--a randomized clinical trial.
To assess whether OA patients attending a clinical nurse specialist (CNS) clinic gain 'additional benefit' compared with those attending a traditional junior hospital doctor (JHD) clinic.
486. Shoulder acute pain in primary health care: is retraining GPs effective? The SAPPHIRE randomized trial: a cost-effectiveness analysis.
作者: Claire McKenna.;Laura Bojke.;Andrea Manca.;Adewale Adebajo.;John Dickson.;Philip Helliwell.;Veronica Morton.;Ian Russell.;David Torgerson.;Judith Watson.
来源: Rheumatology (Oxford). 2009年48卷5期558-63页
To assess the cost-effectiveness of providing practical training to general practitioners (GPs) in shoulder problems, and administering a local anaesthetic (lignocaine) vs steroidal (cortisone) injection.
487. Adalimumab is effective and well tolerated in treating patients with ankylosing spondylitis who have advanced spinal fusion.
作者: Martin Rudwaleit.;Ignazio Olivieri.;Kyriaki A Boki.;Eduard N Griep.;Pentti Järvinen.;Robert L Wong.;Martina Kron.;Sonja Kary.;Hartmut Kupper.
来源: Rheumatology (Oxford). 2009年48卷5期551-7页
To evaluate the effectiveness and safety of adalimumab in treating patients with AS and advanced structural damage.
488. Cardiovascular safety and gastrointestinal tolerability of etoricoxib vs diclofenac in a randomized controlled clinical trial (The MEDAL study).
作者: Bernard Combe.;Gary Swergold.;James McLay.;Timothy McCarthy.;Cristiano Zerbini.;Paul Emery.;Laurine Connors.;Amarjot Kaur.;Sean Curtis.;Loren Laine.;Christopher P Cannon.
来源: Rheumatology (Oxford). 2009年48卷4期425-32页
To compare cardiovascular (CV) and other safety and efficacy parameters of etoricoxib 60 and 90 mg, and diclofenac 150 mg.
489. A dynamic exercise programme to improve patients' disability in rheumatoid arthritis: a prospective randomized controlled trial.
作者: Athan Baillet.;Elodie Payraud.;Virginie-Aurélie Niderprim.;Michael J Nissen.;Benoit Allenet.;Patrice François.;Laurent Grange.;Pierre Casez.;Robert Juvin.;Philippe Gaudin.
来源: Rheumatology (Oxford). 2009年48卷4期410-5页
To evaluate the functional, clinical, radiological and quality of life outcomes of a 4-week dynamic exercise programme (DEP) in RA.
490. Febuxostat in the treatment of gout: 5-yr findings of the FOCUS efficacy and safety study.
作者: H R Schumacher.;M A Becker.;E Lloyd.;P A MacDonald.;C Lademacher.
来源: Rheumatology (Oxford). 2009年48卷2期188-94页
This 5-yr study assessed urate-lowering and clinical efficacy and safety of long-term febuxostat therapy in subjects with gout. The primary efficacy end-point was reduction to and maintenance of serum urate (sUA) levels < 6.0 mg/dl.
492. Accuracy of intra-articular injections in peripheral joints performed blindly in patients with rheumatoid arthritis.
作者: R V Lopes.;R N V Furtado.;L Parmigiani.;A Rosenfeld.;A R C Fernandes.;J Natour.
来源: Rheumatology (Oxford). 2008年47卷12期1792-4页
To assess the accuracy of blind IA injections (IAIs) in patients with RA and determine their effectiveness.
493. Shoulder acute pain in primary healthcare: is retraining effective for GP principals? SAPPHIRE--a randomized controlled trial.
作者: J Watson.;P Helliwell.;V Morton.;A Adebajo.;J Dickson.;I Russell.;D Torgerson.
来源: Rheumatology (Oxford). 2008年47卷12期1795-802页
To address the question whether general practitioners (GPs) should receive practical training in shoulder problems and to test whether cortisone injections are better than anaesthetic injections for rotator cuff problems.
494. A novel therapeutic approach to the treatment of scleroderma-associated pulmonary complications: safety and efficacy of combination therapy with imatinib and cyclophosphamide.
作者: I Sabnani.;M J Zucker.;E D Rosenstein.;D A Baran.;L H Arroyo.;P Tsang.;M Zubair.;V Rivera.
来源: Rheumatology (Oxford). 2009年48卷1期49-52页
Scleroderma-related interstitial lung disease (SSc-ILD) has limited therapeutic options due to unclear pathogenesis. Recently, PDGF receptor (PDGFR) amplification has been postulated to cause fibrosis. We hypothesized that a combination of immunosuppressive agents, e.g. cyclophosphamide (CYC) and imatinib (PDGFR inhibitor), might be useful for treating SSc-related ILD. Our objective was to evaluate the safety and efficacy of this combination therapy in scleroderma-related pulmonary disease.
495. Effects of a modular behavioural arthritis education programme: a pragmatic parallel-group randomized controlled trial.
Rheumatology guidelines recommend people with RA receive behavioural self-management education. This study developed a modular behavioural group programme and evaluated its longer term effects on pain, physical and psychological status.
496. In vivo cartilage contact deformation in the healthy human tibiofemoral joint.
作者: J T Bingham.;R Papannagari.;S K Van de Velde.;C Gross.;T J Gill.;D T Felson.;H E Rubash.;G Li.
来源: Rheumatology (Oxford). 2008年47卷11期1622-7页
In vivo cartilage contact deformation is instrumental for understanding human joint function and degeneration. This study measured the total deformation of contacting articular cartilage in the human tibiofemoral joint during in vivo weight-bearing flexion.
497. The clinical effectiveness of static resting splints in early rheumatoid arthritis: a randomized controlled trial.
作者: J Adams.;J Burridge.;M Mullee.;A Hammond.;C Cooper.
来源: Rheumatology (Oxford). 2008年47卷10期1548-53页
To evaluate the effectiveness of static resting splints in early RA.
498. Successful mycophenolate mofetil therapy in nine patients with idiopathic retroperitoneal fibrosis.
To assess the therapeutic benefit of mycophenolate mofetil (MMF) in retroperitoneal fibrosis (RF).
499. Loss of efficacy during long-term infliximab therapy for sight-threatening childhood uveitis.
作者: G Simonini.;M E Zannin.;R Caputo.;F Falcini.;M de Martino.;F Zulian.;R Cimaz.
来源: Rheumatology (Oxford). 2008年47卷10期1510-4页
To describe efficacy and safety of infliximab in the treatment of childhood chronic uveitis during a long-term follow-up.
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