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461. The perceptions of final year medical students in rheumatology workshops when delivered by a consultant and a nurse clinical educator.
To determine whether final year medical students' perceptions of teaching workshops delivered by a consultant rheumatologist are similar those of the same workshops delivered by an experienced nurse clinical educator (NCE).
462. Persistent clinical response to the anti-TNF-alpha antibody infliximab in patients with ankylosing spondylitis over 3 years.
作者: J Braun.;X Baraliakos.;J Brandt.;J Listing.;A Zink.;R Alten.;G Burmester.;E Gromnica-Ihle.;H Kellner.;M Schneider.;H Sörensen.;H Zeidler.;J Sieper.
来源: Rheumatology (Oxford). 2005年44卷5期670-6页
Infliximab, a monoclonal antibody against tumour necrosis factor alpha (TNF-alpha), is approved in Europe for the treatment of patients with active ankylosing spondylitis (AS) who have responded inadequately to conventional therapy. This report provides analyses from a 3-yr extension study, as a follow-up to both the 1- and 2-yr open label extensions of the original 3-month randomized controlled trial of infliximab in patients with AS.
464. Moderately intensive exercise in a temperate pool for patients with rheumatoid arthritis: a randomized controlled study.
The aim of this study was to evaluate the effects of moderately intensive pool exercise therapy on patients with rheumatoid arthritis (RA).
465. Manual therapy in osteoarthritis of the hip: outcome in subgroups of patients.
作者: H L Hoeksma.;J Dekker.;H K Ronday.;F C Breedveld.;C H M Van den Ende.
来源: Rheumatology (Oxford). 2005年44卷4期461-4页
To investigate whether manual therapy has particular benefit in subgroups of patients defined on the basis of hip function, range of joint motion, pain and radiological deterioration.
466. Spa treatment for primary fibromyalgia syndrome: a combination of thalassotherapy, exercise and patient education improves symptoms and quality of life.
作者: T R Zijlstra.;M A F J van de Laar.;H J Bernelot Moens.;E Taal.;L Zakraoui.;J J Rasker.
来源: Rheumatology (Oxford). 2005年44卷4期539-46页
To study the effect of a combination of thalassotherapy, exercise and patient education in people with fibromyalgia.
467. Effects of once-weekly oral alendronate on bone in children on glucocorticoid treatment.
作者: S Rudge.;S Hailwood.;A Horne.;J Lucas.;F Wu.;T Cundy.
来源: Rheumatology (Oxford). 2005年44卷6期813-8页
To determine the effects of once-weekly oral alendronate on indices of bone size, density and resorption in children with chronic illness being treated with glucocorticoids.
468. A randomized controlled trial of intra-articular triamcinolone and/or physiotherapy in shoulder capsulitis.
作者: I Ryans.;A Montgomery.;R Galway.;W G Kernohan.;R McKane.
来源: Rheumatology (Oxford). 2005年44卷4期529-35页
To assess the effectiveness of intra-articular triamcinolone injection and physiotherapy singly or combined in the treatment of adhesive capsulitis of the shoulder.
469. Long-term efficacy and safety of etanercept after readministration in patients with active ankylosing spondylitis.
作者: J Brandt.;J Listing.;H Haibel.;H Sörensen.;A Schwebig.;M Rudwaleit.;J Sieper.;J Braun.
来源: Rheumatology (Oxford). 2005年44卷3期342-8页
Treatment of ankylosing spondylitis (AS) with the tumour necrosis factor alpha (TNF-alpha) receptor fusion protein etanercept has shown efficacy in patients with active disease in randomized controlled trials (RCTs) for limited periods. The objective of the study was to assess the long-term efficacy and safety of etanercept over 1 yr, including discontinuation and readministration.
470. Debridement of plantar callosities in rheumatoid arthritis: a randomized controlled trial.
作者: H J Davys.;D E Turner.;P S Helliwell.;P G Conaghan.;P Emery.;J Woodburn.
来源: Rheumatology (Oxford). 2005年44卷2期207-10页
To compare forefoot pain, pressure and function before and after normal and sham callus treatment in rheumatoid arthritis (RA).
471. Triamcinolone acetonide and hexacetonide intra-articular treatment of symmetrical joints in juvenile idiopathic arthritis: a double-blind trial.
作者: F Zulian.;G Martini.;D Gobber.;M Plebani.;F Zacchello.;P Manners.
来源: Rheumatology (Oxford). 2004年43卷10期1288-91页
Pharmacokinetic studies have shown that the biological effect of triamcinolone acetonide (TA) is equivalent to that of triamcinolone hexacetonide (TH), if used at double the dosage. In this study we compared the efficacy of intra-articular TA at a dose twice that of TH in symmetrically involved joints, in children with juvenile idiopathic arthritis (JIA).
472. The burden of ankylosing spondylitis and the cost-effectiveness of treatment with infliximab (Remicade).
作者: G Kobelt.;P Andlin-Sobocki.;S Brophy.;L Jönsson.;A Calin.;J Braun.
来源: Rheumatology (Oxford). 2004年43卷9期1158-66页
In the past, treatment options for ankylosing spondylitis (AS) have been limited, and the introduction of new treatments such as infliximab will have a noticeable impact on health-care budgets. The objective of this study was therefore to assess the current burden of the disease and estimate the cost-effectiveness of infliximab treatments.
473. Supplementing a home exercise programme with a class-based exercise programme is more effective than home exercise alone in the treatment of knee osteoarthritis.
作者: C J McCarthy.;P M Mills.;R Pullen.;C Roberts.;A Silman.;J A Oldham.
来源: Rheumatology (Oxford). 2004年43卷7期880-6页
The study aimed to compare the relative effectiveness of providing a home-based exercise programme versus home-based exercise supplemented with an 8-week class-based exercise programme in reducing pain and improving function in patients with knee osteoarthritis.
475. Patient-reported outcomes better discriminate active treatment from placebo in randomized controlled trials in rheumatoid arthritis.
作者: V Strand.;S Cohen.;B Crawford.;J S Smolen.;D L Scott.; .
来源: Rheumatology (Oxford). 2004年43卷5期640-7页
Recent randomized controlled trials (RCTs) in rheumatoid arthritis (RA) have used patient- and physician-reported outcomes, ESR and/or CRP as components of ACR response criteria to assess efficacy.
476. Efficacy and safety of leflunomide 10 mg versus 20 mg once daily in patients with active rheumatoid arthritis: multinational double-blind, randomized trial.
To compare the efficacy and safety profile of two daily maintenance doses of leflunomide, 10 mg and 20 mg, for the treatment of active rheumatoid arthritis (RA).
477. Celecoxib 200 mg q.d. is efficacious in the management of osteoarthritis of the knee or hip regardless of the time of dosing.
作者: K Stengaard-Pedersen.;R Ekesbo.;A-L Karvonen.;M Lyster.
来源: Rheumatology (Oxford). 2004年43卷5期592-5页
The primary objective was to demonstrate equivalence between a.m. and p.m. dosing of celecoxib 200 mg q.d. An equivalence assessment of q.d. vs b.i.d. dosing was a secondary objective.
478. Improved clinical status in fibromyalgia patients treated with individualized homeopathic remedies versus placebo.
作者: I R Bell.;D A Lewis.;A J Brooks.;G E Schwartz.;S E Lewis.;B T Walsh.;C M Baldwin.
来源: Rheumatology (Oxford). 2004年43卷5期577-82页
To assess the efficacy of individualized classical homeopathy in the treatment of fibromyalgia.
479. The reliability, validity and responsiveness of an aggregated locomotor function (ALF) score in patients with osteoarthritis of the knee.
The aggregated locomotor function (ALF) score, a simple measure of observed locomotor function, using timed walking, stairs and transfers, was developed and evaluated for intra-tester reliability, criterion-related validity and responsiveness in a sample of patients with knee osteoarthritis.
480. The health assessment questionnaire (HAQ) is strongly predictive of good outcome in early diffuse scleroderma: results from an analysis of two randomized controlled trials in early diffuse scleroderma.
Scoring poorly on the health assessment questionnaire (HAQ) has recently been shown to be a strong predictor of morbidity and mortality in rheumatoid arthritis (RA), while a good HAQ score is predictive of a better outcome. In patients presenting with early diffuse scleroderma prognosis is variable. Our goal was to determine possible baseline predictors of future good outcomes.
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