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441. Hormonal replacement therapy does not affect self-estimated pain or experimental pain responses in post-menopausal women suffering from fibromyalgia: a double-blind, randomized, placebo-controlled trial.
作者: Kent D Stening.;Olle Eriksson.;Karl G Henriksson.;Jan Brynhildsen.;Lotta Lindh-Åstrand.;Göran Berg.;Mats Hammar.;Asa Amandusson.;Anders Blomqvist.
来源: Rheumatology (Oxford). 2011年50卷3期544-51页
FM is a condition that preferentially affects women. Sex hormones, and in particular oestrogens, have been shown to affect pain processing and pain sensitivity, and oestrogen deficit has been considered a potentially promoting factor for FM. However, the effects of oestrogen treatment in patients suffering from FM have not been studied. Here, we examined the effect of transdermal oestrogen substitution treatment on experimental as well as self-estimated pain in women suffering from FM.
442. Homeopathy has clinical benefits in rheumatoid arthritis patients that are attributable to the consultation process but not the homeopathic remedy: a randomized controlled clinical trial.
作者: Sarah Brien.;Laurie Lachance.;Phil Prescott.;Clare McDermott.;George Lewith.
来源: Rheumatology (Oxford). 2011年50卷6期1070-82页
To assess whether any benefits from adjunctive homeopathic intervention in patients with RA are due to the homeopathic consultation, homeopathic remedies or both.
443. Gene profiling predicts rheumatoid arthritis responsiveness to IL-1Ra (anakinra).
作者: Carine Bansard.;Thierry Lequerré.;Céline Derambure.;Olivier Vittecoq.;Martine Hiron.;Alain Daragon.;Sophie Pouplin.;Maryvonne Daveau.;Olivier Boyer.;François Tron.;Xavier Le Loët.;Jean-Philippe Salier.
来源: Rheumatology (Oxford). 2011年50卷2期283-92页
The overall non-response rate to biologics remains 30-40% for patients with RA resistant to MTX. The objective of this study was to predict responsiveness to the anakinra-MTX combination by peripheral blood mononuclear cell gene profiling in order to optimize treatment choice.
444. Efficacy of tadalafil in secondary Raynaud's phenomenon resistant to vasodilator therapy: a double-blind randomized cross-over trial.
作者: Padmanabha D Shenoy.;Sudeep Kumar.;Lalan K Jha.;Sunil K Choudhary.;Uttam Singh.;Ramnath Misra.;Vikas Agarwal.
来源: Rheumatology (Oxford). 2010年49卷12期2420-8页
To evaluate the efficacy of tadalafil as add-on therapy in secondary RP resistant to vasodilators.
445. Mobilization of endothelial progenitor cells by intravenous cyclophosphamide in patients with systemic sclerosis.
作者: Yoshiaki Furuya.;Yuka Okazaki.;Kenzou Kaji.;Shinichi Sato.;Kazuhiko Takehara.;Masataka Kuwana.
来源: Rheumatology (Oxford). 2010年49卷12期2375-80页
To evaluate the effects of i.v. CYC on the number of circulating endothelial progenitor cells (EPCs) in patients with SSc, and the potential association of the EPC response with CYC's effect for treating interstitial lung disease (ILD).
446. Benefits 8 years after a remission induction regime with an infliximab and methotrexate combination in early rheumatoid arthritis.
作者: Victoria Bejarano.;Philip G Conaghan.;Mark A Quinn.;Benazir Saleem.;Paul Emery.
来源: Rheumatology (Oxford). 2010年49卷10期1971-4页
To ascertain whether a 1-year remission induction therapy with an infliximab-MTX (INF-MTX) combination in patients with early RA provided sustained benefit after INF cessation compared with conventional treatment.
447. Can training in musculoskeletal examination skills be effectively delivered by undergraduate students as part of the standard curriculum?
作者: Martin E Perry.;Joanne M Burke.;Lorraine Friel.;Max Field.
来源: Rheumatology (Oxford). 2010年49卷9期1756-61页
There is a need to improve competence of musculoskeletal system (MSS) examination in medical students and junior doctors. Peer-assisted learning (PAL) is a technique whereby students learn from and with each other. This study aimed to determine whether PAL can be integrated into standard undergraduate medical curricula to improve MSS examination using the gait, arms, legs, spine (GALS) screening tool.
448. Efficacy and safety of various repeat treatment dosing regimens of rituximab in patients with active rheumatoid arthritis: results of a Phase III randomized study (MIRROR).
作者: Andrea Rubbert-Roth.;Paul P Tak.;Cristiano Zerbini.;Jean-Luc Tremblay.;Luis Carreño.;Gillian Armstrong.;Neil Collinson.;Tim M Shaw.; .
来源: Rheumatology (Oxford). 2010年49卷9期1683-93页
To evaluate the efficacy and safety of three dosing and repeat treatment regimens of rituximab (RTX) plus MTX in patients with active RA.
449. Clinical manifestations and responsiveness to adalimumab are similar in patients with ankylosing spondylitis with and without concomitant psoriasis.
作者: Jürgen Braun.;Martin Rudwaleit.;Sonja Kary.;Martina Kron.;Robert L Wong.;Hartmut Kupper.
来源: Rheumatology (Oxford). 2010年49卷8期1578-89页
To compare the clinical manifestations of spinal disease, peripheral arthritis and enthesitis, and to evaluate the effectiveness of adalimumab in a large cohort of patients with AS in relation to the presence or absence of psoriasis.
450. Etanercept improves linear growth and bone mass acquisition in MTX-resistant polyarticular-course juvenile idiopathic arthritis.
作者: An D Billiau.;Michèle Loop.;Phu-Quoc Le.;Françoise Berthet.;Pierre Philippet.;Ahmad Kasran.;Carine H Wouters.
来源: Rheumatology (Oxford). 2010年49卷8期1550-8页
Chronic inflammation in juvenile idiopathic arthritis interferes with linear growth and bone mass acquisition. We prospectively evaluated and compared linear growth and evolution of bone mass acquisition and body composition in MTX-resistant polyarticular-course JIA (polyJIA) patients started on etanercept and in recently diagnosed polyJIA patients started on MTX monotherapy.
451. Effect of bosentan on skin fibrosis in patients with systemic sclerosis: a prospective, open-label, non-comparative trial.
作者: Annegret Kuhn.;Merle Haust.;Vincent Ruland.;Ramona Weber.;Pablo Verde.;Gerd Felder.;Christian Ohmann.;Kristina Gensch.;Thomas Ruzicka.
来源: Rheumatology (Oxford). 2010年49卷7期1336-45页
To assess the effect of the ET-receptor antagonist bosentan on skin fibrosis and functionality in patients with SSc.
452. Lack of effect of 8 weeks atorvastatin on microvascular endothelial function in patients with systemic sclerosis.
作者: Hala Y Sadik.;Tonia L Moore.;Andy Vail.;Andrea Murray.;Marina Anderson.;Andrew Blann.;Ariane L Herrick.
来源: Rheumatology (Oxford). 2010年49卷5期990-6页
The aim of this study was to test the hypothesis that statin therapy confers benefit on the microvasculature, including improving endothelial function, in patients with SSc.
453. Tendon friction rubs in early diffuse systemic sclerosis: prevalence, characteristics and longitudinal changes in a randomized controlled trial.
作者: Puja P Khanna.;Daniel E Furst.;Philip J Clements.;Paul Maranian.;Lilavati Indulkar.;Dinesh Khanna.; .
来源: Rheumatology (Oxford). 2010年49卷5期955-9页
To characterize the baseline tendon friction rubs (TFRs) in early dcSSc and to evaluate the association of change in TFR over 6 and 12 months with changes in modified Rodnan skin score (MRSS) and HAQ-Disability Index (HAQ-DI) over 12 and 24 months, respectively.
454. How to improve DAS28 use in daily clinical practice?--a pilot study of a nurse-led intervention.
作者: Laura T C van Hulst.;Marjonne C W Creemers.;Jaap Fransen.;Linda C Li.;Richard Grol.;Marlies E J L Hulscher.;Piet L C M van Riel.
来源: Rheumatology (Oxford). 2010年49卷4期741-8页
To determine whether DAS28 measurements by a specialized nurse, before the rheumatologist visit, in combination with the advice to rheumatologists to reach a DAS28 < or = 3.2, had beneficial effects on disease activity and medication prescription in patients with RA and to explore possible predictors for variation in medication changes and reasons for non-adherence to the advice to reach a DAS28 < or = 3.2.
455. The BILAG multi-centre open randomized controlled trial comparing ciclosporin vs azathioprine in patients with severe SLE.
作者: Bridget Griffiths.;Paul Emery.;Vicky Ryan.;David Isenberg.;Mohammed Akil.;Robert Thompson.;Peter Maddison.;Ian D Griffiths.;Alice Lorenzi.;Sarah Miles.;Deva Situnayake.;Lee Suan Teh.;Mike Plant.;Christina Hallengren.;Ola Nived.;Gunnar Sturfelt.;Kuntal Chakravarty.;Tim Tait.;Caroline Gordon.
来源: Rheumatology (Oxford). 2010年49卷4期723-32页
To determine whether low-dose ciclosporin was a more effective corticosteroid-sparing agent than AZA in patients with SLE.
456. Effect of the dual endothelin receptor antagonist bosentan on Raynaud's phenomenon secondary to systemic sclerosis: a double-blind prospective, randomized, placebo-controlled pilot study.
作者: Van Anh Nguyen.;Klaus Eisendle.;Ingrid Gruber.;Beate Hugl.;Daniela Reider.;Norbert Reider.
来源: Rheumatology (Oxford). 2010年49卷3期583-7页
To investigate the efficacy of the endothelin receptor antagonist, bosentan, in patients with RP secondary to SSc without pre-existing digital ulcers.
457. Long-term treatment of relapsing Wegener's granulomatosis with 15-deoxyspergualin.
To determine the safety and efficacy of prolonged treatment with 15-deoxyspergualin (DSG, gusperimus) in patients with relapsing WG.
458. Clinical relevance of C-reactive protein in ankylosing spondylitis and evaluation of the NSAIDs/coxibs' treatment effect on C-reactive protein.
To evaluate the clinical relevance of CRP in AS and investigate the treatment effect of NSAIDs/coxibs on CRP.
459. Long-term outcome of systemic sclerosis-associated pulmonary arterial hypertension treated with bosentan as first-line monotherapy followed or not by the addition of prostanoids or sildenafil.
作者: David Launay.;Olivier Sitbon.;Jérôme Le Pavec.;Laurent Savale.;Colas Tchérakian.;Azzedine Yaïci.;Lara Achouh.;Florence Parent.;Xavier Jais.;Gérald Simonneau.;Marc Humbert.
来源: Rheumatology (Oxford). 2010年49卷3期490-500页
Data on long-term efficacy of bosentan, an oral dual ET receptor antagonist, in SSc-associated pulmonary arterial hypertension (SSc-PAH) are lacking. We aimed to describe the long-term outcome of SSc-PAH treated with first-line monotherapy bosentan followed or not by the addition of prostanoids or sildenafil.
460. Nicotine-patch therapy on mucocutaneous lesions of Behcet's disease: a case series.
作者: Giovanni Ciancio.;Matteo Colina.;Renato La Corte.;Andrea Lo Monaco.;Francesco De Leonardis.;Francesco Trotta.;Marcello Govoni.
来源: Rheumatology (Oxford). 2010年49卷3期501-4页
We report the use of nicotine-patch therapy on active mucocutaneous lesions of Behçet's disease (BD).
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