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381. Experience with rituximab in scleroderma: results from a 1-year, proof-of-principle study.
作者: Dimitrios Daoussis.;Stamatis-Nick C Liossis.;Athanassios C Tsamandas.;Christina Kalogeropoulou.;Alexandra Kazantzi.;Chaido Sirinian.;Maria Karampetsou.;Georgios Yiannopoulos.;Andrew P Andonopoulos.
来源: Rheumatology (Oxford). 2010年49卷2期271-80页
To assess the efficacy of rituximab (RTX) in SSc.
382. The decrease of soluble RAGE levels in rheumatoid arthritis patients following hormone replacement therapy is associated with increased bone mineral density and diminished bone/cartilage turnover: a randomized controlled trial.
作者: Rille Pullerits.;Helena Forsblad d'Elia.;Andrej Tarkowski.;Hans Carlsten.
来源: Rheumatology (Oxford). 2009年48卷7期785-90页
The aim of the study was to prospectively investigate the effects of HRT on serum soluble receptor for advanced glycation end product (sRAGE) levels in RA patients and to determine whether sRAGE production is related to bone/cartilage metabolism.
383. Intra-articular clodronate for the treatment of knee osteoarthritis: dose ranging study vs hyaluronic acid.
作者: Maurizio Rossini.;Ombretta Viapiana.;Roberta Ramonda.;Gerolamo Bianchi.;Ignazio Olivieri.;Giovanni Lapadula.;Silvano Adami.
来源: Rheumatology (Oxford). 2009年48卷7期773-8页
Bisphosphonates may have a chondroprotective effect in patients with knee OA (KOA), but the results of clinical trials with oral bisphosphonates have been contradictory. In this Phase 2 randomized, partially blind clinical trial, we tested the efficacy of IA clodronate vs HA in patients with primary KOA.
384. Do OA patients gain additional benefit from care from a clinical nurse specialist?--a randomized clinical trial.
To assess whether OA patients attending a clinical nurse specialist (CNS) clinic gain 'additional benefit' compared with those attending a traditional junior hospital doctor (JHD) clinic.
385. Shoulder acute pain in primary health care: is retraining GPs effective? The SAPPHIRE randomized trial: a cost-effectiveness analysis.
作者: Claire McKenna.;Laura Bojke.;Andrea Manca.;Adewale Adebajo.;John Dickson.;Philip Helliwell.;Veronica Morton.;Ian Russell.;David Torgerson.;Judith Watson.
来源: Rheumatology (Oxford). 2009年48卷5期558-63页
To assess the cost-effectiveness of providing practical training to general practitioners (GPs) in shoulder problems, and administering a local anaesthetic (lignocaine) vs steroidal (cortisone) injection.
386. Cardiovascular safety and gastrointestinal tolerability of etoricoxib vs diclofenac in a randomized controlled clinical trial (The MEDAL study).
作者: Bernard Combe.;Gary Swergold.;James McLay.;Timothy McCarthy.;Cristiano Zerbini.;Paul Emery.;Laurine Connors.;Amarjot Kaur.;Sean Curtis.;Loren Laine.;Christopher P Cannon.
来源: Rheumatology (Oxford). 2009年48卷4期425-32页
To compare cardiovascular (CV) and other safety and efficacy parameters of etoricoxib 60 and 90 mg, and diclofenac 150 mg.
387. A dynamic exercise programme to improve patients' disability in rheumatoid arthritis: a prospective randomized controlled trial.
作者: Athan Baillet.;Elodie Payraud.;Virginie-Aurélie Niderprim.;Michael J Nissen.;Benoit Allenet.;Patrice François.;Laurent Grange.;Pierre Casez.;Robert Juvin.;Philippe Gaudin.
来源: Rheumatology (Oxford). 2009年48卷4期410-5页
To evaluate the functional, clinical, radiological and quality of life outcomes of a 4-week dynamic exercise programme (DEP) in RA.
388. Febuxostat in the treatment of gout: 5-yr findings of the FOCUS efficacy and safety study.
作者: H R Schumacher.;M A Becker.;E Lloyd.;P A MacDonald.;C Lademacher.
来源: Rheumatology (Oxford). 2009年48卷2期188-94页
This 5-yr study assessed urate-lowering and clinical efficacy and safety of long-term febuxostat therapy in subjects with gout. The primary efficacy end-point was reduction to and maintenance of serum urate (sUA) levels < 6.0 mg/dl.
390. Shoulder acute pain in primary healthcare: is retraining effective for GP principals? SAPPHIRE--a randomized controlled trial.
作者: J Watson.;P Helliwell.;V Morton.;A Adebajo.;J Dickson.;I Russell.;D Torgerson.
来源: Rheumatology (Oxford). 2008年47卷12期1795-802页
To address the question whether general practitioners (GPs) should receive practical training in shoulder problems and to test whether cortisone injections are better than anaesthetic injections for rotator cuff problems.
391. Effects of a modular behavioural arthritis education programme: a pragmatic parallel-group randomized controlled trial.
Rheumatology guidelines recommend people with RA receive behavioural self-management education. This study developed a modular behavioural group programme and evaluated its longer term effects on pain, physical and psychological status.
392. The clinical effectiveness of static resting splints in early rheumatoid arthritis: a randomized controlled trial.
作者: J Adams.;J Burridge.;M Mullee.;A Hammond.;C Cooper.
来源: Rheumatology (Oxford). 2008年47卷10期1548-53页
To evaluate the effectiveness of static resting splints in early RA.
393. Short-term efficacy of combination methotrexate and infliximab in patients with ankylosing spondylitis: a clinical and magnetic resonance imaging correlation.
作者: E K Li.;J F Griffith.;V W Lee.;Y-X Wang.;T K Li.;K K Lee.;L-S Tam.
来源: Rheumatology (Oxford). 2008年47卷9期1358-63页
To examine the short-term efficacy and safety of MTX in combination with infliximab compared with infliximab and placebo in the treatment of AS using MRI to monitor its effect.
394. Cost-effectiveness of advising the use of topical or oral ibuprofen for knee pain; the TOIB study [ISRCTN: 79353052].
作者: E Castelnuovo.;P Cross.;S Mt-Isa.;A Spencer.;M Underwood.; .
来源: Rheumatology (Oxford). 2008年47卷7期1077-81页
Advice to use topical or oral NSAIDs is equally effective for the treatment of knee pain in older people. The ingredient cost of topical preparations is typically more than oral preparations, but could save costs because they have fewer adverse effects. A cost-utility study is needed to decide on their comparative cost effectiveness.
395. Resistin in serum is associated with higher levels of IL-1Ra in post-menopausal women with rheumatoid arthritis.
作者: H Forsblad d'Elia.;R Pullerits.;H Carlsten.;M Bokarewa.
来源: Rheumatology (Oxford). 2008年47卷7期1082-7页
The aim of this study was to investigate associations between serum levels of resistin, an adipokine and markers of inflammation, bone metabolism, plasma lipids and kidney function in post-menopausal RA patients and to evaluate if HRT during 2 yrs affected resistin levels.
396. Treatment impact on estimated medical expenditure and job loss likelihood in rheumatoid arthritis: re-examining quality of life outcomes from a randomized placebo-controlled clinical trial with abatacept.
作者: J C Cole.;T Li.;P Lin.;R MacLean.;G V Wallenstein.
来源: Rheumatology (Oxford). 2008年47卷7期1044-50页
Quality of life (QoL) improvement is important to demonstrate in RA clinical trials, but can be abstract. More meaningful measures of QoL include medical expenditure and job loss, aspects that have marked importance for RA patients, physicians and society. We re-examined previous positive QoL findings for abatacept over placebo by converting existing QoL measures into estimated medical expenditure and estimated likelihood of job loss.
397. Single-point acupuncture and physiotherapy for the treatment of painful shoulder: a multicentre randomized controlled trial.
作者: J Vas.;C Ortega.;V Olmo.;F Perez-Fernandez.;L Hernandez.;I Medina.;J M Seminario.;A Herrera.;F Luna.;E Perea-Milla.;C Mendez.;F Madrazo.;C Jimenez.;M A Ruiz.;I Aguilar.
来源: Rheumatology (Oxford). 2008年47卷6期887-93页
Evaluate the efficacy of acupuncture associated with physiotherapy for patients with painful shoulder.
398. Value of serum cartilage oligomeric matrix protein as a prognostic marker of large-joint damage in rheumatoid arthritis--data from the RAPIT study.
作者: Z de Jong.;M Munneke.;V Vilim.;A H Zwinderman.;H M Kroon.;H K Ronday.;W F Lems.;B A C Dijkmans.;F C Breedveld.;T P M Vliet Vlieland.;J M W Hazes.;J Degroot.
来源: Rheumatology (Oxford). 2008年47卷6期868-71页
To investigate the utility of serum COMP level measurements as a predictor of future damage of the weight-bearing (large) joints in RA patients participating in intensive exercise.
399. Cod liver oil (n-3 fatty acids) as an non-steroidal anti-inflammatory drug sparing agent in rheumatoid arthritis.
作者: B Galarraga.;M Ho.;H M Youssef.;A Hill.;H McMahon.;C Hall.;S Ogston.;G Nuki.;J J F Belch.
来源: Rheumatology (Oxford). 2008年47卷5期665-9页
Dose-dependant gastrointestinal and cardiovascular side-effects limit the use of NSAIDs in the management of RA. The n-3 essential fatty acids (EFAs) have previously demonstrated some anti-inflammatory and NSAID-sparing properties. The objective of this study was to determine whether cod liver oil supplementation helps reduce daily NSAID requirement of patients with RA.
400. Low-intensity pulsed ultrasound for chronic patellar tendinopathy: a randomized, double-blind, placebo-controlled trial.
作者: S J Warden.;B R Metcalf.;Z S Kiss.;J L Cook.;C R Purdam.;K L Bennell.;K M Crossley.
来源: Rheumatology (Oxford). 2008年47卷4期467-71页
Patellar tendinopathy (PT) is a common and significant clinical condition for which there are few established interventions. One intervention that is currently being used clinically to manage PT symptoms is the introduction of low-intensity pulsed ultrasound (LIPUS). The aim of this study was to investigate the clinical efficacy of LIPUS in the management of PT symptoms.
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