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381. Rilonacept for gout flare prevention during initiation of uric acid-lowering therapy: results from the PRESURGE-2 international, phase 3, randomized, placebo-controlled trial.
作者: Essack Mitha.;H Ralph Schumacher.;Leon Fouche.;Shue-Fen Luo.;Steven P Weinstein.;George D Yancopoulos.;Jian Wang.;Shirletta King-Davis.;Robert R Evans.
来源: Rheumatology (Oxford). 2013年52卷7期1285-92页
To evaluate the efficacy and safety of IL-1 inhibitor rilonacept (IL-1 Trap) for gout flare (GF) prevention during initiation of uric acid-lowering therapy (ULT) with allopurinol in a multiregional phase 3 clinical trial.
382. Effects of subcutaneous and intravenous golimumab on inflammatory biomarkers in patients with rheumatoid arthritis: results of a phase 1, randomized, open-label trial.
作者: Mittie K Doyle.;Mahboob U Rahman.;Bart Frederick.;Charles A Birbara.;Dick de Vries.;Gary Toedter.;Xiaoying Wu.;Dion Chen.;Veena K Ranganath.;Mark E Westerman.;Daniel E Furst.
来源: Rheumatology (Oxford). 2013年52卷7期1214-9页
To evaluate the effects of the anti-TNF-α monoclonal antibody golimumab, administered by s.c. injection or i.v. infusion, on markers of inflammation in patients with RA.
383. Efficacy and safety of leflunomide in DMARD-naive patients with early rheumatoid arthritis: comparison of a loading and a fixed-dose regimen.
作者: Maurizio Cutolo.;Horatiu Bolosiu.;Gilles Perdriset.; .
来源: Rheumatology (Oxford). 2013年52卷6期1132-40页
To assess the efficacy of LEF administered with or without a loading dose in DMARD-naïve patients with early RA.
384. Effect on bone turnover markers of once-yearly intravenous infusion of zoledronic acid versus daily oral risedronate in patients treated with glucocorticoids.
作者: Jean-Pierre Devogelaer.;Philip Sambrook.;David M Reid.;Stefan Goemaere.;Sophia Ish-Shalom.;Julien Collette.;Guoqin Su.;Christina Bucci-Rechtweg.;Philemon Papanastasiou.;Jean-Yves Reginster.
来源: Rheumatology (Oxford). 2013年52卷6期1058-69页
Long-term glucocorticoid use is accompanied by rapid bone loss; however, early treatment with bisphosphonates prevents bone loss and reduces fracture risk. The aim of this study was to examine the effects of two bisphosphonates, i.v. zoledronic acid (ZOL) versus oral risedronate (RIS), on bone turnover markers (BTMs) in subjects with glucocorticoid-induced osteoporosis (GIO).
385. Ayurvedic medicine offers a good alternative to glucosamine and celecoxib in the treatment of symptomatic knee osteoarthritis: a randomized, double-blind, controlled equivalence drug trial.
作者: Arvind Chopra.;Manjit Saluja.;Girish Tillu.;Sanjeev Sarmukkaddam.;Anuradha Venugopalan.;Gumdal Narsimulu.;Rohini Handa.;Venil Sumantran.;Ashwinikumar Raut.;Lata Bichile.;Kalpana Joshi.;Bhushan Patwardhan.
来源: Rheumatology (Oxford). 2013年52卷8期1408-17页
To demonstrate clinical equivalence between two standardized Ayurveda (India) formulations (SGCG and SGC), glucosamine and celecoxib (NSAID).
386. Methotrexate for pain relief in knee osteoarthritis: an open-label study.
作者: Claire Y J Wenham.;Andrew J Grainger.;Elizabeth M A Hensor.;Anna R Caperon.;Zoe R Ash.;Philip G Conaghan.
来源: Rheumatology (Oxford). 2013年52卷5期888-92页
Synovitis is very common in knee OA and associated with pain. This open-label study evaluated an anti-synovitis therapy, MTX, for pain relief in knee OA.
388. Low-dose prednisolone in early rheumatoid arthritis inhibits collagen type I degradation by matrix metalloproteinases as assessed by serum 1CTP--a possible mechanism for specific inhibition of radiological destruction.
作者: Inga-Lill Engvall.;Björn Svensson.;Annelies Boonen.;Désirée van der Heijde.;Ulf H Lerner.;Ingiäld Hafström.; .
来源: Rheumatology (Oxford). 2013年52卷4期733-42页
To study the effects of low-dose prednisolone on the osteoclast-regulating proteins osteoprotegerin (OPG) and RANK ligand (RANKL) and on markers of bone resorption, 1CTP generated by MMPs and CTX-1 generated by cathepsin K, in patients with early RA in relation to inflammation and joint destruction.
389. Association between -871C>T promoter polymorphism in the B-cell activating factor gene and the response to rituximab in rheumatoid arthritis patients.
作者: Adeline Ruyssen-Witrand.;Stéphanie Rouanet.;Bernard Combe.;Maxime Dougados.;Xavier Le Loët.;Jean Sibilia.;Jacques Tebib.;Xavier Mariette.;Arnaud Constantin.
来源: Rheumatology (Oxford). 2013年52卷4期636-41页
To determine whether a functional single-nucleotide polymorphism in the B-cell activating factor (BAFF) gene correlates with the response to treatment with rituximab (RTX) in RA.
390. Treatment of complex regional pain syndrome type I with neridronate: a randomized, double-blind, placebo-controlled study.
作者: Massimo Varenna.;Silvano Adami.;Maurizio Rossini.;Davide Gatti.;Luca Idolazzi.;Francesca Zucchi.;Nazzarena Malavolta.;Luigi Sinigaglia.
来源: Rheumatology (Oxford). 2013年52卷3期534-42页
Complex regional pain syndrome type I (CRPS-I) is a severely disabling pain syndrome for which no definite treatment has been established. The aim of this multi-centre, randomized, double-blind placebo-controlled trial was to test the efficacy of the amino-bisphosphonate neridronate in patients with CRP-I.
391. Positive synovial vascularity in patients with low disease activity indicates smouldering inflammation leading to joint damage in rheumatoid arthritis: time-integrated joint inflammation estimated by synovial vascularity in each finger joint.
作者: Jun Fukae.;Masato Isobe.;Akemi Kitano.;Mihoko Henmi.;Fumihiko Sakamoto.;Akihiro Narita.;Takeya Ito.;Akio Mitsuzaki.;Masato Shimizu.;Kazuhide Tanimura.;Megumi Matsuhashi.;Tamotsu Kamishima.;Tatsuya Atsumi.;Takao Koike.
来源: Rheumatology (Oxford). 2013年52卷3期523-8页
To investigate the relationship between synovial vascularity and joint damage progression in each finger joint of patients with RA under low disease activity during treatment with biologic agents.
392. The effect of foot orthoses on balance, foot pain and disability in elderly women with osteoporosis: a randomized clinical trial.
作者: Cecília de Morais Barbosa.;Manoel Barros Bértolo.;João Francisco Marques Neto.;Ibsen Bellini Coimbra.;Michael Davitt.;Eduardo de Paiva Magalhães.
来源: Rheumatology (Oxford). 2013年52卷3期515-22页
To evaluate the effect of insoles with medial arch support and metatarsal pad on balance, foot pain and disability in elderly women with osteoporosis.
393. Factors limiting participation in arthritis self-management programmes: an exploration of barriers and patient preferences within a randomized controlled trial.
作者: Ilana N Ackerman.;Rachelle Buchbinder.;Richard H Osborne.
来源: Rheumatology (Oxford). 2013年52卷3期472-9页
To improve understanding of barriers to participation in community-based arthritis self-management programmes and patient preferences for self-management education.
394. Postgraduate education to increase adherence to a Dutch physiotherapy practice guideline for hip and knee OA: a randomized controlled trial.
作者: Wilfred F Peter.;Philip J van der Wees.;John Verhoef.;Zuzana de Jong.;Leti van Bodegom-Vos.;Wim K H A Hilberdink.;Marta Fiocco.;Thea P M Vliet Vlieland.
来源: Rheumatology (Oxford). 2013年52卷2期368-75页
To compare the effectiveness of two educational courses aiming to improve adherence to recommendations in a Dutch physiotherapy practice guideline for hip and knee OA.
395. Comparison of three enthesitis indices in a multicentre, randomized, placebo-controlled trial of golimumab in ankylosing spondylitis (GO-RAISE).
作者: Désirée van der Heijde.;Jürgen Braun.;Atul Deodhar.;Robert D Inman.;Stephen Xu.;Michael E Mack.;Benjamin Hsu.
来源: Rheumatology (Oxford). 2013年52卷2期321-5页
To compare the abilities of three enthesitis indices to detect improvement in entheseal tenderness with the TNF antagonist golimumab in AS.
396. A randomized, double-blind, placebo-controlled trial of low-dose oral prednisolone for treating painful hand osteoarthritis.
作者: Claire Y J Wenham.;Elizabeth M A Hensor.;Andrew J Grainger.;Richard Hodgson.;Sharon Balamoody.;Caroline J Doré.;Paul Emery.;Philip G Conaghan.
来源: Rheumatology (Oxford). 2012年51卷12期2286-94页
Anti-inflammatory therapies are effective analgesics for OA. This study determined whether low-dose oral prednisolone (PNL) was an effective analgesic for hand OA.
397. Large-joint damage in patients with early rheumatoid arthritis and its association with treatment strategy and damage of the small joints.
作者: Linda Dirven.;Marianne van den Broek.;Herman M Kroon.;Bernard A M Grillet.;K Huub Han.;Pit J S M Kerstens.;Tom W J Huizinga.;Willem F Lems.;Cornelia F Allaart.
来源: Rheumatology (Oxford). 2012年51卷12期2262-8页
To determine the prevalence of large-joint damage and the association with small-joint damage in patients with RA after 8 years of low DAS (≤2.4)-targeted treatment with different treatment strategies.
398. A randomized controlled trial of a cognitive behavioural patient education intervention vs a traditional information leaflet to address the cardiovascular aspects of rheumatoid disease.
作者: Holly John.;Elizabeth D Hale.;Gareth J Treharne.;George D Kitas.;Douglas Carroll.
来源: Rheumatology (Oxford). 2013年52卷1期81-90页
Cardiovascular disease (CVD) is responsible for 50% of the excess mortality for patients with RA. This study aimed to evaluate a novel 8-week cognitive behavioural patient education intervention designed to effect behavioural change with regard to modifiable CVD risk factors in people with RA.
399. Efficacy and safety of certolizumab pegol in a broad population of patients with active rheumatoid arthritis: results from the REALISTIC phase IIIb study.
作者: Michael E Weinblatt.;Roy Fleischmann.;Tom W J Huizinga.;Paul Emery.;Janet Pope.;Elena M Massarotti.;Ronald F van Vollenhoven.;Jürgen Wollenhaupt.;Clifton O Bingham.;Ben Duncan.;Niti Goel.;Owen R Davies.;Maxime Dougados.
来源: Rheumatology (Oxford). 2012年51卷12期2204-14页
To investigate the efficacy and safety of certolizumab pegol (CZP) in a broad population of patients with active RA.
400. Foot kinematics in people with medial compartment knee osteoarthritis.
作者: Pazit Levinger.;Hylton B Menz.;Adam D Morrow.;Julian A Feller.;John R Bartlett.;Neil R Bergman.
来源: Rheumatology (Oxford). 2012年51卷12期2191-8页
Foot orthoses are commonly used in the management of knee OA, although the relationship between foot function and knee OA is still unclear. The purpose of the study was to examine foot function during walking in people with and without medial compartment knee OA.
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