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361. Narrow-band imaging does not improve detection of colorectal polyps when compared to conventional colonoscopy: a randomized controlled trial and meta-analysis of published studies.
作者: Luis C Sabbagh.;Ludovic Reveiz.;Diego Aponte.;Sylvia de Aguiar.
来源: BMC Gastroenterol. 2011年11卷100页
A colonoscopy may frequently miss polyps and cancers. A number of techniques have emerged to improve visualization and to reduce the rate of adenoma miss.
362. Association between RUNX3 promoter methylation and gastric cancer: a meta-analysis.
作者: Xiao-yuan Fan.;Xin-lei Hu.;Tie-mei Han.;Na-na Wang.;Yi-miao Zhu.;Wen Hu.;Zhen-hua Ma.;Chen-jing Zhang.;Xiang Xu.;Zai-yuan Ye.;Chun-mao Han.;Wen-sheng Pan.
来源: BMC Gastroenterol. 2011年11卷92页
Runt-related transcription factor 3 (RUNX3) is a member of the runt-domain family of transcription factors and has been reported to be a candidate tumor suppressor in gastric cancer. However, the association between RUNX3 promoter methylation and gastric cancer remains unclear.
363. Nonlinear reduction in risk for colorectal cancer by fruit and vegetable intake based on meta-analysis of prospective studies.
作者: Dagfinn Aune.;Rosa Lau.;Doris S M Chan.;Rui Vieira.;Darren C Greenwood.;Ellen Kampman.;Teresa Norat.
来源: Gastroenterology. 2011年141卷1期106-18页
The association between fruit and vegetable intake and colorectal cancer risk has been investigated by many studies but is controversial because of inconsistent results and weak observed associations. We summarized the evidence from cohort studies in categorical, linear, and nonlinear, dose-response meta-analyses.
364. Polyethylene glycol vs. sodium phosphate for bowel preparation: a treatment arm meta-analysis of randomized controlled trials.
Results of meta-analyses of randomized trials comparing PEG and NaP are inconsistent and have not included trials comparing either or both preps to less traditional ones.
365. Consumption of large amounts of Allium vegetables reduces risk for gastric cancer in a meta-analysis.
作者: Yong Zhou.;Wen Zhuang.;Wen Hu.;Guan-Jian Liu.;Tai-Xiang Wu.;Xiao-Ting Wu.
来源: Gastroenterology. 2011年141卷1期80-9页
The chemopreventive effects of Allium vegetables (onions, garlic, shallots, leeks, chives, and so forth) have been studied extensively, although their effect on gastric cancer risk is controversial. We performed a meta-analysis of cohort and case-control studies to analyze this association.
366. Helicobacter pylori infection and circulating ghrelin levels - a systematic review.
The nature of the association between ghrelin, an orexigenic hormone produced mainly in the stomach, and Helicobacter pylori (H pylori), a bacterium that colonises the stomach, is still controversial. We examined available evidence to determine whether an association exists between the two; and if one exists, in what direction.
367. Association between HLA-DRB1 alleles polymorphism and hepatocellular carcinoma: a meta-analysis.
作者: Zhong-Hua Lin.;Yong-Ning Xin.;Quan-Jiang Dong.;Qing Wang.;Xiang-Jun Jiang.;Shu-Hui Zhan.;Ying Sun.;Shi-Ying Xuan.
来源: BMC Gastroenterol. 2010年10卷145页
HLA-DRB1 allele polymorphisms have been reported to be associated with hepatocellular carcinoma susceptibility, but the results of these previous studies have been inconsistent. The purpose of the present study was to explore whether specific HLA-DRB1 alleles (DRB1*07, DRB1*12, DRB1*15) confer susceptibility to hepatocellular carcinoma.
368. A functional single nucleotide polymorphism in mucin 1, at chromosome 1q22, determines susceptibility to diffuse-type gastric cancer.
作者: Norihisa Saeki.;Akira Saito.;Il Ju Choi.;Keitaro Matsuo.;Sumiko Ohnami.;Hirohiko Totsuka.;Suenori Chiku.;Aya Kuchiba.;Yeon-Su Lee.;Kyong-Ah Yoon.;Myeong-Cherl Kook.;Sook Ryun Park.;Young-Woo Kim.;Hideo Tanaka.;Kazuo Tajima.;Hiroshi Hirose.;Fumihiko Tanioka.;Yoshihiro Matsuno.;Haruhiko Sugimura.;Shunji Kato.;Tsuneya Nakamura.;Tomohiro Nishina.;Wataru Yasui.;Kazuhiko Aoyagi.;Hiroki Sasaki.;Kazuyoshi Yanagihara.;Hitoshi Katai.;Tadakazu Shimoda.;Teruhiko Yoshida.;Yusuke Nakamura.;Setsuo Hirohashi.;Hiromi Sakamoto.
来源: Gastroenterology. 2011年140卷3期892-902页
Two major types of gastric cancer, intestinal and diffuse, develop through distinct mechanisms; the diffuse type is considered to be more influenced by genetic factors, although the mechanism is unknown. Our previous genome-wide association study associated 3 single nucleotide polymorphisms (SNPs) with diffuse-type gastric cancer (DGC); 1 was a functional SNP (rs2294008) in prostate stem cell antigen (PSCA), but the loci of the other 2 were not investigated.
369. Laparoscopic versus conventional appendectomy--a meta-analysis of randomized controlled trials.
作者: Xiaohang Li.;Jialin Zhang.;Lixuan Sang.;Wenliang Zhang.;Zhiqiang Chu.;Xin Li.;Yongfeng Liu.
来源: BMC Gastroenterol. 2010年10卷129页
Although laparoscopic surgery has been available for a long time and laparoscopic cholecystectomy has been performed universally, it is still not clear whether open appendectomy (OA) or laparoscopic appendectomy (LA) is the most appropriate surgical approach to acute appendicitis. The purpose of this work is to compare the therapeutic effects and safety of laparoscopic and conventional "open" appendectomy by means of a meta-analysis.
370. Quantitative meta-analysis identifies brain regions activated during rectal distension in irritable bowel syndrome.
The responsiveness of the central nervous system is altered in patients with irritable bowel syndrome (IBS). However, because of variations in experimental paradigms, analytic techniques, and reporting practices, little consensus exists on brain responses to visceral stimulation. We aimed to identify brain regions consistently activated by supraliminal rectal stimulation in IBS patients and healthy subjects (controls) by performing a quantitative meta-analysis of published studies.
371. A meta-analysis for the effect of prophylactic GTN on the incidence of post-ERCP pancreatitis and on the successful rate of cannulation of bile ducts.
Glyceryl trinitrate (GTN) has been shown to be able to relax the sphincter of Oddi (SO) both in animals and humans. Theoretically, the use of these compounds during and after endoscopic retrograde cholangiopancreatgraphy (ERCP) could relax the biliary and pancreatic sphincters, facilitating cannulation of common bile duct (CBD) during the procedure, or minimizing potential pancreatic outflow obstruction after the procedure. However, clinical trials evaluating the protective effect of GTN on the post-endoscopic retrograde cholangiopancreatgraphy pancreatitis (PEP) have yielded inconclusive results. This meta-analysis is to systematically assess the effect of prophylactic administration of glyceryl trinitrate (GTN) on the prevention of PEP and the effect on the cannulation of bile ducts.
372. Meta-analysis of hepatitis C virus vaccine efficacy in chimpanzees indicates an importance for structural proteins.
Studies in patients and chimpanzees that spontaneously cleared hepatitis C virus (HCV) infections demonstrated that natural immunity to the virus is induced during primary infections and that this immunity can be cross protective. These discoveries led to optimism about prophylactic HCV vaccines, and several studies were performed in chimpanzees, although most included fewer than 6 animals. To draw meaningful conclusions about the efficacy of HCV vaccines in chimpanzees, we performed statistical analyses of data from previously published studies from different groups.
373. Meta-analysis of radiofrequency ablation versus hepatic resection for small hepatocellular carcinoma.
作者: Yanming Zhou.;Yanfang Zhao.;Bin Li.;Donghui Xu.;Zhengfeng Yin.;Feng Xie.;Jiamei Yang.
来源: BMC Gastroenterol. 2010年10卷78页
There is no clear consensus on the better therapy [radiofrequency ablation (RFA) versus hepatic resection (HR)] for small hepatocellular carcinoma (HCC) eligible for surgical treatments. This study is a meta-analysis of the available evidence.
374. Tenofovir and entecavir are the most effective antiviral agents for chronic hepatitis B: a systematic review and Bayesian meta-analyses.
作者: Gloria Woo.;George Tomlinson.;Yasunori Nishikawa.;Matthew Kowgier.;Morris Sherman.;David K H Wong.;Ba Pham.;Wendy J Ungar.;Thomas R Einarson.;E Jenny Heathcote.;Murray Krahn.
来源: Gastroenterology. 2010年139卷4期1218-29页
The relative efficacies of licensed antiviral therapies for treatment-naive chronic hepatitis B (CHB) infection in randomized controlled trials have not been determined. We evaluated the relative efficacies of the first 12 months of CHB treatments.
375. Organ failure and infection of pancreatic necrosis as determinants of mortality in patients with acute pancreatitis.
作者: Maxim S Petrov.;Satyanarayan Shanbhag.;Mandira Chakraborty.;Anthony R J Phillips.;John A Windsor.
来源: Gastroenterology. 2010年139卷3期813-20页
There is no consistency between the individual studies in the literature on whether organ failure (OF) or infected pancreatic necrosis (IPN) is the main determinant of severity in acute pancreatitis. We aimed to statistically aggregate the available data and determine the pooled influence of OF and IPN on mortality in patients with acute pancreatitis.
376. Moxibustion for ulcerative colitis: a systematic review and meta-analysis.
作者: Dong-Hyo Lee.;Jong-In Kim.;Myeong Soo Lee.;Tae-Young Choi.;Sun-Mi Choi.;Edzard Ernst.
来源: BMC Gastroenterol. 2010年10卷36页
Complementary and alternative medicine (CAM) is increasingly used for treatment of inflammatory bowel disease (IBD). Acupuncture-type treatments are among the most popular options. Several studies have reported that moxibustion is effective in ulcerative colitis (UC). The objective of this review was to assess the clinical evidence for or against moxibustion as a treatment for UC.
377. Meta-analysis shows that detection of circulating tumor cells indicates poor prognosis in patients with colorectal cancer.
作者: Nuh N Rahbari.;Maximilian Aigner.;Kristian Thorlund.;Nathan Mollberg.;Edith Motschall.;Katrin Jensen.;Markus K Diener.;Markus W Büchler.;Moritz Koch.;Jürgen Weitz.
来源: Gastroenterology. 2010年138卷5期1714-26页
The prognostic significance of circulating (CTCs) and disseminated tumor cells in patients with colorectal cancer (CRC) is controversial. We performed a meta-analysis of available studies to assess whether the detection of tumor cells in the blood and bone marrow (BM) of patients diagnosed with primary CRC can be used as a prognostic factor.
378. Genome-wide association analysis in primary sclerosing cholangitis.
作者: Tom H Karlsen.;Andre Franke.;Espen Melum.;Arthur Kaser.;Johannes Roksund Hov.;Tobias Balschun.;Benedicte A Lie.;Annika Bergquist.;Christoph Schramm.;Tobias J Weismüller.;Daniel Gotthardt.;Christian Rust.;Eva E R Philipp.;Teresa Fritz.;Liesbet Henckaerts.;Rinse K Weersma.;Pieter Stokkers.;Cyriel Y Ponsioen.;Cisca Wijmenga.;Martina Sterneck.;Michael Nothnagel.;Jochen Hampe.;Andreas Teufel.;Heiko Runz.;Philip Rosenstiel.;Adolf Stiehl.;Severine Vermeire.;Ulrich Beuers.;Michael P Manns.;Erik Schrumpf.;Kirsten Muri Boberg.;Stefan Schreiber.
来源: Gastroenterology. 2010年138卷3期1102-11页
We aimed to characterize the genetic susceptibility to primary sclerosing cholangitis (PSC) by means of a genome-wide association analysis of single nucleotide polymorphism (SNP) markers.
379. Systematic review and meta-analysis on the adverse events of rimonabant treatment: considerations for its potential use in hepatology.
作者: Norberto C Chavez-Tapia.;Felix I Tellez-Avila.;Giorgio Bedogni.;Lory S Crocè.;Flora Masutti.;Claudio Tiribelli.
来源: BMC Gastroenterol. 2009年9卷75页
The cannabinoid-1 receptor blockers have been proposed in the management of obesity and obesity-related liver diseases (fatty liver as NAFLD or NASH). Due to increasing number of patients to be potentially treated and the need to assess the advantage of this treatment in terms of risk/benefit, we analyze the side events reported during the treatment with rimonabant by a systematic review and meta-analysis of all randomized controlled studies.
380. Psychometric evaluation of patient-reported outcomes in irritable bowel syndrome randomized controlled trials: a Rome Foundation report.
作者: Brennan Spiegel.;Michael Camilleri.;Roger Bolus.;Viola Andresen.;William D Chey.;Sheri Fehnel.;Allen Mangel.;Nicholas J Talley.;William E Whitehead.
来源: Gastroenterology. 2009年137卷6期1944-53.e1-3页
There is debate about how best to measure patient-reported outcomes (PROs) in irritable bowel syndrome (IBS). We pooled data to measure the psychometric properties of IBS end points, including binary responses (eg, "adequate relief") and 50% improvement in symptom severity.
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