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361. Diagnostic accuracy of cardiac positron emission tomography versus single photon emission computed tomography for coronary artery disease: a bivariate meta-analysis.
作者: Matthew W Parker.;Aline Iskandar.;Brendan Limone.;Andrew Perugini.;Hyejin Kim.;Charles Jones.;Brian Calamari.;Craig I Coleman.;Gary V Heller.
来源: Circ Cardiovasc Imaging. 2012年5卷6期700-7页
Positron emission tomography (PET) myocardial perfusion imaging (MPI) offers technical benefits compared with single photon emission computed tomography (SPECT) MPI, but there has been no systematic comparison of their diagnostic accuracy for coronary artery disease. We performed a bivariate meta-analysis of the published literature to compare the sensitivity and specificity of PET versus SPECT stress MPI for ≥50% stenosis of any epicardial coronary artery in patients with known or suspected coronary artery disease.
362. Association of mild to moderate chronic kidney disease with venous thromboembolism: pooled analysis of five prospective general population cohorts.
作者: Bakhtawar K Mahmoodi.;Ron T Gansevoort.;Inger Anne Næss.;Pamela L Lutsey.;Sigrid K Brækkan.;Nic J G M Veeger.;Ellen E Brodin.;Karina Meijer.;Yingying Sang.;Kunihiro Matsushita.;Stein I Hallan.;Jens Hammerstrøm.;Suzanne C Cannegieter.;Brad C Astor.;Josef Coresh.;Aaron R Folsom.;John-Bjarne Hansen.;Mary Cushman.
来源: Circulation. 2012年126卷16期1964-71页
Recent findings suggest that chronic kidney disease (CKD) may be associated with an increased risk of venous thromboembolism (VTE). Given the high prevalence of mild-to-moderate CKD in the general population, in depth analysis of this association is warranted.
363. Periprocedural heparin bridging in patients receiving vitamin K antagonists: systematic review and meta-analysis of bleeding and thromboembolic rates.
作者: Deborah Siegal.;Jovana Yudin.;Scott Kaatz.;James D Douketis.;Wendy Lim.;Alex C Spyropoulos.
来源: Circulation. 2012年126卷13期1630-9页
Periprocedural bridging with unfractionated heparin or low-molecular-weight heparin aims to reduce the risk of thromboembolic events in patients receiving long-term vitamin K antagonists. Optimal periprocedural anticoagulation has not been established.
364. Systematic review and adjusted indirect comparison meta-analysis of oral anticoagulants in atrial fibrillation.
Oral anticoagulants such as apixaban, dabigatran, and rivaroxaban are alternatives to warfarin for preventing events in patients with atrial fibrillation. Direct comparative studies between agents are unavailable. Our objective was to conduct an adjusted indirect comparison meta-analysis between new oral agents in atrial fibrillation.
366. Percutaneous coronary intervention versus optimal medical therapy in stable coronary artery disease: a systematic review and meta-analysis of randomized clinical trials.
作者: Seema Pursnani.;Frederick Korley.;Ravindra Gopaul.;Pushkar Kanade.;Newry Chandra.;Richard E Shaw.;Sripal Bangalore.
来源: Circ Cardiovasc Interv. 2012年5卷4期476-90页
The role of percutaneous coronary intervention (PCI) in the management of stable coronary artery disease remains controversial. Given advancements in medical therapies and stent technology over the last decade, we sought to evaluate whether PCI, when added to medical therapy, improves outcomes when compared with medical therapy alone.
367. Paclitaxel-coated versus uncoated balloon angioplasty reduces target lesion revascularization in patients with femoropopliteal arterial disease: a meta-analysis of randomized trials.
作者: Salvatore Cassese.;Robert A Byrne.;Ilka Ott.;Gjin Ndrepepa.;Mateja Nerad.;Adnan Kastrati.;Massimiliano Fusaro.
来源: Circ Cardiovasc Interv. 2012年5卷4期582-9页
In disease of the femoropopliteal artery, paclitaxel-coated balloon (PCB) therapy improved angiographic outcomes as compared with uncoated balloon (UCB) angioplasty. Nevertheless, it remains uncertain whether PCB may reduce the need for reintervention.
368. Association of obstructive sleep apnea with risk of serious cardiovascular events: a systematic review and meta-analysis.
作者: Yoon K Loke.;J William L Brown.;Chun Shing Kwok.;Alagaratnam Niruban.;Phyo K Myint.
来源: Circ Cardiovasc Qual Outcomes. 2012年5卷5期720-8页
The relationship between obstructive sleep apnea (OSA) and cardiovascular events remains unclear. We conducted a systematic review to determine the incident risk of cardiovascular events among patients with OSA.
369. Outcome and complications after implantable cardioverter defibrillator therapy in hypertrophic cardiomyopathy: systematic review and meta-analysis.
作者: Arend F L Schinkel.;Pieter A Vriesendorp.;Eric J G Sijbrands.;Luc J L M Jordaens.;Folkert J ten Cate.;Michelle Michels.
来源: Circ Heart Fail. 2012年5卷5期552-9页
Previous observational studies demonstrated that patients with hypertrophic cardiomyopathy at risk for sudden cardiac death (SCD) may benefit from implantable cardioverter defibrillator (ICD) therapy. A complete overview of outcome and complications after ICD therapy is currently not available. This study pools data from published studies on outcome and complications after ICD therapy in patients with hypertrophic cardiomyopathy.
370. Coronary artery calcium and primary prevention risk assessment: what is the evidence? An updated meta-analysis on patient and physician behavior.
作者: Seamus P Whelton.;Khurram Nasir.;Michael J Blaha.;Heidi Gransar.;Thomas S Metkus.;Josef Coresh.;Daniel S Berman.;Roger S Blumenthal.
来源: Circ Cardiovasc Qual Outcomes. 2012年5卷4期601-7页
While the Framingham Risk Score provides a reasonable estimation of risk in certain subgroups, the majority of MIs occur in individuals classified as low or moderate risk. Coronary Artery Calcium (CAC) testing provides an individualized measure of atherosclerotic burden that integrates an individual’s cumulative lifetime risk factor exposure that cannot be obtained from serum markers.
371. Habitual coffee consumption and risk of heart failure: a dose-response meta-analysis.
作者: Elizabeth Mostofsky.;Megan S Rice.;Emily B Levitan.;Murray A Mittleman.
来源: Circ Heart Fail. 2012年5卷4期401-5页
There have been discrepant findings on the association between coffee consumption and risk of incident heart failure.
372. Systematic review and cost-benefit analysis of radial artery access for coronary angiography and intervention.
作者: Matthew D Mitchell.;Jaekyoung A Hong.;Bruce Y Lee.;Craig A Umscheid.;Sarah M Bartsch.;Creighton W Don.
来源: Circ Cardiovasc Qual Outcomes. 2012年5卷4期454-62页
Radial artery access for coronary angiography and interventions has been promoted for reducing hemostasis time and vascular complications compared with femoral access, yet it can take longer to perform and is not always successful, leading to concerns about its cost. We report a cost-benefit analysis of radial catheterization based on results from a systematic review of published randomized controlled trials.
373. Adult bone marrow cell therapy improves survival and induces long-term improvement in cardiac parameters: a systematic review and meta-analysis.
作者: Vinodh Jeevanantham.;Matthew Butler.;Andre Saad.;Ahmed Abdel-Latif.;Ewa K Zuba-Surma.;Buddhadeb Dawn.
来源: Circulation. 2012年126卷5期551-68页
Despite rapid clinical translation and widespread enthusiasm, the therapeutic benefits of adult bone marrow cell (BMC) transplantation in patients with ischemic heart disease continue to remain controversial. A synthesis of the available data is critical to appreciate and underscore the true impact of this promising approach.
374. Validation of 6-minute walk distance as a surrogate end point in pulmonary arterial hypertension trials.
作者: Nicole B Gabler.;Benjamin French.;Brian L Strom.;Harold I Palevsky.;Darren B Taichman.;Steven M Kawut.;Scott D Halpern.
来源: Circulation. 2012年126卷3期349-56页
Nearly all available treatments for pulmonary arterial hypertension have been approved based on change in 6-minute walk distance (Δ6MWD) as a clinically important end point, but its validity as a surrogate end point has never been shown. We aimed to validate the difference in Δ6MWD against the probability of a clinical event in pulmonary arterial hypertension trials.
375. Stent thrombosis with everolimus-eluting stents: meta-analysis of comparative randomized controlled trials.
作者: Tullio Palmerini.;Ajay J Kirtane.;Patrick W Serruys.;Pieter C Smits.;Elvin Kedhi.;Dean Kereiakes.;Diego Sangiorgi.;Letizia Bacchi Reggiani.;Christoph Kaiser.;Hyo-Soo Kim.;Antoinette De Waha.;Flavio Ribichini.;Gregg W Stone.
来源: Circ Cardiovasc Interv. 2012年5卷3期357-64页
Some but not all studies have reported reduced rates of stent thrombosis (ST) with everolimus-eluting stents (EES) compared with other drug-eluting stents (DES). All of these studies were insufficiently powered to reliably detect differences in ST. We therefore performed a meta-analysis of randomized controlled trials comparing the risk of 2-year definite ST between EES and other DES.
376. Meta-analysis of bleeding complications associated with cardiac rhythm device implantation.
作者: Michael L Bernard.;Matthew Shotwell.;Paul J Nietert.;Michael R Gold.
来源: Circ Arrhythm Electrophysiol. 2012年5卷3期468-74页
Many patients receiving cardiac rhythm devices have conditions requiring antiplatelet (AP) and/or anticoagulant (AC) therapy. Current guidelines recommend a heparin-bridging strategy (HBS) for anticoagulated patients with moderate/high risk for thrombosis. Several studies reported lower bleeding risk with continued oral anticoagulation rather than HBS. The best strategy for perioperative management of patients on AP therapy is less clear. The present study was designed as a meta-analysis of device implantation-associated bleeding complications using different AC/AP therapies.
377. Risk of arrhythmia and sudden death in patients with asymptomatic preexcitation: a meta-analysis.
作者: Manoj N Obeyesekere.;Peter Leong-Sit.;David Massel.;Jaimie Manlucu.;Simon Modi.;Andrew D Krahn.;Allan C Skanes.;Raymond Yee.;Lorne J Gula.;George J Klein.
来源: Circulation. 2012年125卷19期2308-15页
The incidence of sudden cardiac death (SCD) and the management of this risk in patients with asymptomatic preexcitation remain controversial. The purpose of this meta-analysis was to define the incidence of SCD and supraventricular tachycardia in patients with asymptomatic Wolff-Parkinson-White ECG pattern.
378. Testosterone supplementation in heart failure: a meta-analysis.
作者: Mustafa Toma.;Finlay A McAlister.;Erin E Coglianese.;Venkatesan Vidi.;Samip Vasaiwala.;Jeffrey A Bakal.;Paul W Armstrong.;Justin A Ezekowitz.
来源: Circ Heart Fail. 2012年5卷3期315-21页
Low testosterone is an independent predictor of reduced exercise capacity and poor clinical outcomes in patients with heart failure (HF). We sought to determine whether testosterone therapy improves exercise capacity in patients with stable chronic HF.
379. Associations between incident ischemic stroke events and stroke and cardiovascular disease-related genome-wide association studies single nucleotide polymorphisms in the Population Architecture Using Genomics and Epidemiology study.
作者: Cara L Carty.;Petra Buzková.;Myriam Fornage.;Nora Franceschini.;Shelley Cole.;Gerardo Heiss.;Lucia A Hindorff.;Barbara V Howard.;Sue Mann.;Lisa W Martin.;Ying Zhang.;Tara C Matise.;Ross Prentice.;Alexander P Reiner.;Charles Kooperberg.
来源: Circ Cardiovasc Genet. 2012年5卷2期210-6页
Genome-wide association studies (GWAS) have identified loci associated with ischemic stroke (IS) and cardiovascular disease (CVD) in European-descent individuals, but their replication in different populations has been largely unexplored.
380. Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.
作者: Kati Kristiansson.;Markus Perola.;Emmi Tikkanen.;Johannes Kettunen.;Ida Surakka.;Aki S Havulinna.;Alena Stancáková.;Chris Barnes.;Elisabeth Widen.;Eero Kajantie.;Johan G Eriksson.;Jorma Viikari.;Mika Kähönen.;Terho Lehtimäki.;Olli T Raitakari.;Anna-Liisa Hartikainen.;Aimo Ruokonen.;Anneli Pouta.;Antti Jula.;Antti J Kangas.;Pasi Soininen.;Mika Ala-Korpela.;Satu Männistö.;Pekka Jousilahti.;Lori L Bonnycastle.;Marjo-Riitta Järvelin.;Johanna Kuusisto.;Francis S Collins.;Markku Laakso.;Matthew E Hurles.;Aarno Palotie.;Leena Peltonen.;Samuli Ripatti.;Veikko Salomaa.
来源: Circ Cardiovasc Genet. 2012年5卷2期242-9页
Genome-wide association (GWA) studies have identified several susceptibility loci for metabolic syndrome (MetS) component traits, but have had variable success in identifying susceptibility loci to the syndrome as an entity. We conducted a GWA study on MetS and its component traits in 4 Finnish cohorts consisting of 2637 MetS cases and 7927 controls, both free of diabetes, and followed the top loci in an independent sample with transcriptome and nuclear magnetic resonance-based metabonomics data. Furthermore, we tested for loci associated with multiple MetS component traits using factor analysis, and built a genetic risk score for MetS.
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