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341. Dietary fiber intake reduces risk for colorectal adenoma: a meta-analysis.
作者: Qiwen Ben.;Yunwei Sun.;Rui Chai.;Aihua Qian.;Bin Xu.;Yaozong Yuan.
来源: Gastroenterology. 2014年146卷3期689-699.e6页
Reports on the association between dietary fiber intake and risk of colorectal adenoma (CRA), the precursor of colorectal cancer, have been inconsistent. We conducted a meta-analysis of case-control and cohort studies to analyze this association.
342. Treatment of chronic HCV genotype 1 infection with telaprevir: a Bayesian mixed treatment comparison of fixed-length and response-guided treatment regimens in treatment-naïve and -experienced patients.
Telaprevir (TVR) has been approved for response-guided-therapy (RGT) of chronic hepatitis C (HCV) genotype-1-infection in treatment-naïve and -experienced patients. In RGT-regimens patients that did not achieve extended rapid-virological-response (eRVR) within the first 4-12 weeks undergo treatment for 48-weeks, whereas in fixed-length-treatment (FLT) patients are treated for a fixed-duration regardless of their RVR.
343. Risk of surgery for inflammatory bowel diseases has decreased over time: a systematic review and meta-analysis of population-based studies.
作者: Alexandra D Frolkis.;Jonathan Dykeman.;María E Negrón.;Jennifer Debruyn.;Nathalie Jette.;Kirsten M Fiest.;Talia Frolkis.;Herman W Barkema.;Kevin P Rioux.;Remo Panaccione.;Subrata Ghosh.;Samuel Wiebe.;Gilaad G Kaplan.
来源: Gastroenterology. 2013年145卷5期996-1006页
The inflammatory bowel diseases (IBDs) are chronic diseases that often require surgery. However, the risk of requirement of surgery over time has not been well characterized. We performed a systematic review and meta-analysis to establish the cumulative risk of surgery among patients with IBD and evaluated how this risk has changed over time.
344. Dietary fiber intake reduces risk for gastric cancer: a meta-analysis.
作者: Zhizhong Zhang.;Gelin Xu.;Minmin Ma.;Jie Yang.;Xinfeng Liu.
来源: Gastroenterology. 2013年145卷1期113-120.e3页
The association between dietary fiber intake and gastric cancer risk has been investigated by many studies, with inconclusive results. We conducted a meta-analysis of case-control and cohort studies to analyze this association.
345. Transarterial chemoembolization for hepatocellular carcinoma with portal vein tumor thrombus: a meta-analysis.
作者: Tong-Chun Xue.;Xiao-Ying Xie.;Lan Zhang.;Xin Yin.;Bo-Heng Zhang.;Zheng-Gang Ren.
来源: BMC Gastroenterol. 2013年13卷60页
Although transarterial chemoembolization (TACE) has been used extensively for advanced hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT), no consensus has been reached and an evidence base for practice is lacking. This meta-analysis evaluated the efficacy and safety of TACE for treatment of HCC with PVTT.
346. Meta-analysis: preoperative transcatheter arterial chemoembolization does not improve prognosis of patients with resectable hepatocellular carcinoma.
作者: Yanming Zhou.;Xiaofeng Zhang.;Lupeng Wu.;Feng Ye.;Xu Su.;Lehua Shi.;Bin Li.
来源: BMC Gastroenterol. 2013年13卷51页
Long-term outcomes of partial liver resection of hepatocellular carcinoma (HCC) remain satisfactory due to high incidences of recurrence. This study was intended to see whether preoperative transcatheter arterial chemoembolization (TACE) reduces postoperative tumor recurrences and prolongs survival of patients with resectable HCC.
347. Consumption of coffee associated with reduced risk of liver cancer: a meta-analysis.
Epidemiologic studies have reported inconsistent results regarding coffee consumption and the risk of liver cancer. We performed a meta-analysis of published case-control and cohort studies to investigate the association between coffee consumption and liver cancer.
348. Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
作者: Ulrike Peters.;Shuo Jiao.;Fredrick R Schumacher.;Carolyn M Hutter.;Aaron K Aragaki.;John A Baron.;Sonja I Berndt.;Stéphane Bézieau.;Hermann Brenner.;Katja Butterbach.;Bette J Caan.;Peter T Campbell.;Christopher S Carlson.;Graham Casey.;Andrew T Chan.;Jenny Chang-Claude.;Stephen J Chanock.;Lin S Chen.;Gerhard A Coetzee.;Simon G Coetzee.;David V Conti.;Keith R Curtis.;David Duggan.;Todd Edwards.;Charles S Fuchs.;Steven Gallinger.;Edward L Giovannucci.;Stephanie M Gogarten.;Stephen B Gruber.;Robert W Haile.;Tabitha A Harrison.;Richard B Hayes.;Brian E Henderson.;Michael Hoffmeister.;John L Hopper.;Thomas J Hudson.;David J Hunter.;Rebecca D Jackson.;Sun Ha Jee.;Mark A Jenkins.;Wei-Hua Jia.;Laurence N Kolonel.;Charles Kooperberg.;Sébastien Küry.;Andrea Z Lacroix.;Cathy C Laurie.;Cecelia A Laurie.;Loic Le Marchand.;Mathieu Lemire.;David Levine.;Noralane M Lindor.;Yan Liu.;Jing Ma.;Karen W Makar.;Keitaro Matsuo.;Polly A Newcomb.;John D Potter.;Ross L Prentice.;Conghui Qu.;Thomas Rohan.;Stephanie A Rosse.;Robert E Schoen.;Daniela Seminara.;Martha Shrubsole.;Xiao-Ou Shu.;Martha L Slattery.;Darin Taverna.;Stephen N Thibodeau.;Cornelia M Ulrich.;Emily White.;Yongbing Xiang.;Brent W Zanke.;Yi-Xin Zeng.;Ben Zhang.;Wei Zheng.;Li Hsu.; .
来源: Gastroenterology. 2013年144卷4期799-807.e24页
Heritable factors contribute to the development of colorectal cancer. Identifying the genetic loci associated with colorectal tumor formation could elucidate the mechanisms of pathogenesis.
349. Role of vitamin K2 in preventing the recurrence of hepatocellular carcinoma after curative treatment: a meta-analysis of randomized controlled trials.
作者: Irbaz Bin Riaz.;Haris Riaz.;Talha Riaz.;Sophia Rahman.;Muhammad Amir.;Maaz B Badshah.;Abdul Nafey Kazi.
来源: BMC Gastroenterol. 2012年12卷170页
Hepatocellular cancer is notorious for recurrence even after curative therapy. High recurrence determines the long term prognosis of the patients. Vitamin K2 has been tested in trials for its effect on prevention of recurrence and improving survival. The results are inconclusive from individual trials and in our knowledge no systematic review which entirely focuses on Vitamin K2 as a chemo preventive agent is available to date. This review is an attempt to pool all the existing trials together and update the existing knowledge on the topic.
350. Green tea consumption and risk of esophageal cancer: a meta-analysis of epidemiologic studies.
Green tea has shown the role of chemoprevention for cancer. Recently, several studies suggested that green tea intake may have effect on esophageal cancer risk, whereas the results were inconsistent.
351. Does the variable-stiffness colonoscope makes colonoscopy easier? A meta-analysis of the efficacy of the variable stiffness colonoscope compared with the standard adult colonoscope.
The variable-stiffness colonoscope (VSC) appears to have advantages over the standard adult colonoscope (SAC), although data are conflicting. To provide a comprehensive up-to-date review, we conducted a meta-analysis to compare the efficacies of the VSC and SAC.
352. Efficacy of conservative treatment, without necrosectomy, for infected pancreatic necrosis: a systematic review and meta-analysis.
作者: Venigalla Pratap Mouli.;Vishnubhatla Sreenivas.;Pramod Kumar Garg.
来源: Gastroenterology. 2013年144卷2期333-340.e2页
Conservative treatment (intensive care, a combination of antimicrobial agents, and nutritional support, with or without drainage of the infected fluid) has recently been shown to be effective for patients with infected pancreatic necrosis (IPN), but the data from individual studies are not robust enough to recommend it as the standard of care. We performed a systematic review and meta-analysis of studies related to primary conservative management for IPN.
353. Statins are associated with a reduced risk of hepatocellular cancer: a systematic review and meta-analysis.
作者: Siddharth Singh.;Preet Paul Singh.;Abha Goyal Singh.;Mohammad Hassan Murad.;William Sanchez.
来源: Gastroenterology. 2013年144卷2期323-332页
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide. Several studies have shown that statins could have chemopreventive effects on HCC. We performed a systematic review and meta-analysis of studies that evaluated the effects of statins on the risk of HCC.
354. Polymorphisms in ERCC1, GSTs, TS and MTHFR predict clinical outcomes of gastric cancer patients treated with platinum/5-Fu-based chemotherapy: a systematic review.
作者: Zhen Wang.;Jun-qiang Chen.;Jin-lu Liu.;Xin-gan Qin.;Yuan Huang.
来源: BMC Gastroenterol. 2012年12卷137页
Despite genetic polymorphism in response to platinum/5-Fu chemotherapy in gastric cancer (GC) has been studied, data reported so far are conflicting and critical consideration is needed before translation to the treatment of GC.
355. Efficacy of ursodeoxycholic acid in treating intrahepatic cholestasis of pregnancy: a meta-analysis.
作者: Yannick Bacq.;Loïc Sentilhes.;Humberto B Reyes.;Anna Glantz.;Jurate Kondrackiene.;Tomas Binder.;Pier Luigi Nicastri.;Anna Locatelli.;Annarosa Floreani.;Ismael Hernandez.;Vincent Di Martino.
来源: Gastroenterology. 2012年143卷6期1492-501页
We performed a meta-analysis to evaluate the effects of ursodeoxycholic acid (UDCA) on pruritus, liver test results, and outcomes of babies born to women with intrahepatic cholestasis of pregnancy (ICP).
356. The relationship between urban environment and the inflammatory bowel diseases: a systematic review and meta-analysis.
作者: Ing Shian Soon.;Natalie A Molodecky.;Doreen M Rabi.;William A Ghali.;Herman W Barkema.;Gilaad G Kaplan.
来源: BMC Gastroenterol. 2012年12卷51页
The objective of this study was to conduct a systematic review with meta-analysis of studies assessing the association between living in an urban environment and the development of the Crohn's disease (CD) or ulcerative colitis (UC).
357. Diagnostic accuracy of the aspartate aminotransferase-to-platelet ratio index for the prediction of hepatitis B-related fibrosis: a leading meta-analysis.
作者: Wenwen Jin.;Zhonghua Lin.;Yongning Xin.;Xiangjun Jiang.;Quanjiang Dong.;Shiying Xuan.
来源: BMC Gastroenterol. 2012年12卷14页
The aspartate aminotransferase-to-platelet ratio index (APRI), a tool with limited expense and widespread availability, is a promising noninvasive alternative to liver biopsy for detecting hepatic fibrosis. The objective of this study was to systematically review the performance of the APRI in predicting significant fibrosis and cirrhosis in hepatitis B-related fibrosis.
358. Body mass index increases risk for colorectal adenomas based on meta-analysis.
作者: Qiwen Ben.;Wei An.;Ying Jiang.;Xianbao Zhan.;Yiqi Du.;Quan Cai Cai.;Jie Gao.;Zhaoshen Li.
来源: Gastroenterology. 2012年142卷4期762-72页
There have been inconsistent results published about the relationship between excess body weight, expressed as increased body mass index (BMI), and risk of colorectal adenoma (CRA). We conducted a meta-analysis to explore this relationship. We focused on whether the relationship varied based on the sex of the study subjects, study design, features of the polyps, or potential confounders, including alcohol use, nonsteroidal anti-inflammatory drug use, smoking, and exercise.
359. Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors.
作者: Jesper B Andersen.;Bart Spee.;Boris R Blechacz.;Itzhak Avital.;Mina Komuta.;Andrew Barbour.;Elizabeth A Conner.;Matthew C Gillen.;Tania Roskams.;Lewis R Roberts.;Valentina M Factor.;Snorri S Thorgeirsson.
来源: Gastroenterology. 2012年142卷4期1021-1031.e15页
Cholangiocarcinoma is a heterogeneous disease with a poor outcome that accounts for 5%-10% of primary liver cancers. We characterized its genomic and genetic features and associated these with patient responses to therapy.
360. Nonsteroidal anti-inflammatory drug use reduces risk of adenocarcinomas of the esophagus and esophagogastric junction in a pooled analysis.
作者: Linda M Liao.;Thomas L Vaughan.;Douglas A Corley.;Michael B Cook.;Alan G Casson.;Farin Kamangar.;Christian C Abnet.;Harvey A Risch.;Carol Giffen.;Neal D Freedman.;Wong-Ho Chow.;Shahram Sadeghi.;Nirmala Pandeya.;David C Whiteman.;Liam J Murray.;Leslie Bernstein.;Marilie D Gammon.;Anna H Wu.
来源: Gastroenterology. 2012年142卷3期442-452.e5; quiz e22-3页
Regular use of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) has been reported to reduce risks of esophageal adenocarcinoma (EAC) and esophagogastric junctional adenocarcinoma (EGJA). However, individual studies have been too small to accurately assess the effects of medication type, frequency, or duration of use. We performed a pooled analysis to investigate these associations.
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