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341. Noninvasive imaging for the diagnosis of coronary artery disease: focusing the development of new diagnostic technology.
New tests, such as magnetic resonance imaging (MRI) and electron-beam computed tomography (CT), are being developed for the diagnosis of coronary artery disease.
342. Antithrombotic therapy to prevent stroke in patients with atrial fibrillation: a meta-analysis.
To characterize the efficacy and safety of anticoagulants and antiplatelet agents for prevention of stroke in patients with atrial fibrillation.
343. Low-molecular-weight heparins compared with unfractionated heparin for treatment of acute deep venous thrombosis. A meta-analysis of randomized, controlled trials.
作者: M K Gould.;A D Dembitzer.;R L Doyle.;T J Hastie.;A M Garber.
来源: Ann Intern Med. 1999年130卷10期800-9页
Low-molecular-weight heparins may simplify the management of deep venous thrombosis. A critical clinical issue is whether this more convenient therapy is as safe and effective as treatment with unfractionated heparin.
344. Low-molecular-weight heparins compared with unfractionated heparin for treatment of acute deep venous thrombosis. A cost-effectiveness analysis.
Low-molecular-weight heparins are effective for treating venous thrombosis, but their cost-effectiveness has not been rigorously assessed.
345. Cost-effectiveness of alternative test strategies for the diagnosis of coronary artery disease.
The appropriate roles for several diagnostic tests for coronary disease are uncertain.
347. Clinical guideline, part 2. Screening for thyroid disease: an update. American College of Physicians.
To review information on the benefits of screening with a sensitive thyroid-stimulating hormone (TSH) test for thyroid dysfunction in asymptomatic patients seeking primary care for other reasons. This paper focuses on whether screening should be aimed at detection of subclinical thyroid dysfunction and whether persons with mildly abnormal TSH levels can benefit.
348. The effect of antilymphocyte induction therapy on renal allograft survival. A meta-analysis of individual patient-level data. Anti-Lymphocyte Antibody Induction Therapy Study Group.
Randomized, controlled trials have not shown that the perioperative use of antilymphocyte antibodies (induction therapy) improves survival of cadaveric kidney allografts. This study combined individual patient-level data from published trials to examine the effect of induction therapy on allograft survival.
349. Estimates of the cost-effectiveness of a single course of interferon-alpha 2b in patients with histologically mild chronic hepatitis C.
作者: W G Bennett.;Y Inoue.;J R Beck.;J B Wong.;S G Pauker.;G L Davis.
来源: Ann Intern Med. 1997年127卷10期855-65页
Chronic hepatitis C is a major cause of illness and death in the United States. Interferon-alpha 2b can induce clinical, biochemical, and virologic remission in some patients with chronic hepatitis C, but the long-term cost-effectiveness of this treatment, particularly in patients with histologically mild disease, is unknown.
350. Effect of HMGcoA reductase inhibitors on stroke. A meta-analysis of randomized, controlled trials.
Stroke is a leading cause of death in the industrialized world, and hypercholesterolemia may be a risk factor for stroke.
351. Somatostatin or octreotide compared with H2 antagonists and placebo in the management of acute nonvariceal upper gastrointestinal hemorrhage: a meta-analysis.
To determine the efficacy of somatostatin or octreotide for the treatment of acute nonvariceal upper gastrointestinal hemorrhage.
352. Effect of angiotensin-converting enzyme inhibitors on the progression of nondiabetic renal disease: a meta-analysis of randomized trials. Angiotensin-Converting-Enzyme Inhibition and Progressive Renal Disease Study Group.
The effect of angiotensin-converting enzyme (ACE) inhibitors in slowing the decline in renal function in nondiabetic renal disease varies among studies.
353. Effect of antihypertensive drug treatment on cardiovascular outcomes in women and men. A meta-analysis of individual patient data from randomized, controlled trials. The INDANA Investigators.
作者: F Gueyffier.;F Boutitie.;J P Boissel.;S Pocock.;J Coope.;J Cutler.;T Ekbom.;R Fagard.;L Friedman.;M Perry.;R Prineas.;E Schron.
来源: Ann Intern Med. 1997年126卷10期761-7页
Trials of drug therapy for hypertension have shown that such therapy has a clear overall benefit in preventing cardiovascular disease. Although these trials have included slightly more women than men, it is still not clear whether treatment benefit is similar for both sexes.
354. Chemotherapy plus radiotherapy compared with radiotherapy alone in the treatment of locally advanced, unresectable, non-small-cell lung cancer. A meta-analysis.
Survival of patients with locally advanced, unresectable (stage III), non-small-cell lung cancer treated with radiotherapy is poor. Trials of the addition of chemotherapy to radiotherapy have produced conflicting results.
355. Cost-effectiveness of interferon-alpha and conventional chemotherapy in chronic myelogenous leukemia.
作者: M W Kattan.;Y Inoue.;F J Giles.;M Talpaz.;H Ozer.;F Guilhot.;E Zuffa.;S L Huber.;J R Beck.
来源: Ann Intern Med. 1996年125卷7期541-8页
To compare the cost-effectiveness of interferon-alpha with that of hydroxyurea as initial therapy for patients with chronic myelogenous leukemia (CML) in the chronic phase.
356. Non-insulin-dependent diabetes mellitus in minorities in the United States.
To review the available information on prevalence, complications, and mortality of non-insulin-dependent diabetes mellitus and primary and secondary prevention activities in black persons, Hispanic persons, Native Americans, and Asians and Pacific Islanders in the United States.
357. Dietary calcium and blood pressure: a meta-analysis of randomized clinical trials.
作者: P S Allender.;J A Cutler.;D Follmann.;F P Cappuccio.;J Pryer.;P Elliott.
来源: Ann Intern Med. 1996年124卷9期825-31页
To assess the effect of dietary calcium supplementation on blood pressure.
358. Polymerase chain reaction for the diagnosis of HIV infection in adults. A meta-analysis with recommendations for clinical practice and study design.
作者: D K Owens.;M Holodniy.;A M Garber.;J Scott.;S Sonnad.;L Moses.;B Kinosian.;J S Schwartz.
来源: Ann Intern Med. 1996年124卷9期803-15页
To do a meta-analysis of studies that have evaluated the sensitivity and specificity of polymerase chain reaction (PCR) assay for the diagnosis of human immunodeficiency virus (HIV) infection in adults. Evaluating the performance of PCR is difficult because in certain clinical situations, the sensitivity or specificity of PCR may exceed those of the current reference standard tests (enzyme immunoassay followed by confirmatory Western blot analysis). Therefore, an additional goal was to develop recommendations for 1) the design of future evaluative studies of PCR and 2) the use of PCR in persons with suspected HIV infection.
359. Once-daily aminoglycoside dosing in immunocompetent adults: a meta-analysis.
To compare the efficacy, nephrotoxicity, and ototoxicity of once-daily aminoglycoside dosing with those of standard aminoglycoside regimens in immuno-competent adults.
360. The effect of dietary protein restriction on the progression of diabetic and nondiabetic renal diseases: a meta-analysis.
Dietary protein has long been thought to play a role in the progression of chronic renal disease, but clinical trials to date have not consistently shown that dietary protein restriction is beneficial.
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