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3522. Computed tomography of the thorax. Current perspectives.
With improvement in computed tomography (CT) technology, including faster scanning and images with better detail, the indications for CT of the thorax have expanded. In many instances, data collected on earlier-generation scanners no longer apply. This report is an update of CT scanning of the thorax and includes information on the role of CT in diagnosis when specific clinical syndromes and diseases are suspected. It also addresses controversial subjects, such as the role of CT scanning in the staging of bronchogenic carcinoma and the evaluation of the solitary pulmonary nodule, as well as suggesting guidelines for deciding when a CT scan of the thorax is indicated.
3535. The influence of corticosteroids and theophylline on cerebral function. A review.
Evidence indicating that corticosteroid therapy may adversely affect attention and memory in asthmatic subjects is reviewed. The potential impact of corticosteroid dosage levels (high versus low) and treatment regimens (daily versus alternate day) on attention and memory is discussed. Findings indicate that the suppression of ACTH by corticosteroids may have different effects on attention and memory as a function of the sex of the asthmatic patient. The need to establish what the effects of theophylline-induced reductions of cerebral blood flow and cerebral oxygen tension are on higher cognitive processes are outlined. The importance of establishing whether or not medications commonly used for the treatment of asthma create deficits of memory or attention that interfere with medical compliance is emphasized.
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