321. Association between insomnia symptoms and mortality: a prospective study of U.S. men.
作者: Yanping Li.;Xuehong Zhang.;John W Winkelman.;Susan Redline.;Frank B Hu.;Meir Stampfer.;Jing Ma.;Xiang Gao.
来源: Circulation. 2014年129卷7期737-46页
Insomnia complaints are common in older adults and may be associated with mortality risk. However, evidence regarding this association is mixed. Thus, we prospectively examined whether men with insomnia symptoms had an increased risk of mortality during 6 years of follow-up.
322. Long-term coffee consumption and risk of cardiovascular disease: a systematic review and a dose-response meta-analysis of prospective cohort studies.
作者: Ming Ding.;Shilpa N Bhupathiraju.;Ambika Satija.;Rob M van Dam.;Frank B Hu.
来源: Circulation. 2014年129卷6期643-59页
Considerable controversy exists on the association between coffee consumption and cardiovascular disease (CVD) risk. A meta-analysis was performed to assess the dose-response relationship of long-term coffee consumption with CVD risk.
323. Management and outcomes of major bleeding during treatment with dabigatran or warfarin.
作者: Ammar Majeed.;Hun-Gyu Hwang.;Stuart J Connolly.;John W Eikelboom.;Michael D Ezekowitz.;Lars Wallentin.;Martina Brueckmann.;Mandy Fraessdorf.;Salim Yusuf.;Sam Schulman.
来源: Circulation. 2013年128卷21期2325-32页
The aim of this study was to compare the management and prognosis of major bleeding in patients treated with dabigatran or warfarin.
324. Sex-related differences in outcomes after transcatheter aortic valve implantation: a systematic review and meta-analysis.
作者: Zhen-Gang Zhao.;Yan-Biao Liao.;Yong Peng.;Hua Chai.;Wei Liu.;Qiao Li.;Xin Ren.;Xue-Qin Wang.;Xiao-Lin Luo.;Chen Zhang.;Li-Hui Lu.;Qing-Tao Meng.;Chi Chen.;Mao Chen.;Yuan Feng.;De-Jia Huang.
来源: Circ Cardiovasc Interv. 2013年6卷5期543-51页
There were considerable discrepancies with regard to sex-related differences in complications and prognosis after transcatheter aortic valve implantation.
325. Genome-wide association study identifies 3 genomic loci significantly associated with serum levels of homoarginine: the AtheroRemo Consortium.
作者: Marcus E Kleber.;Ilkka Seppälä.;Stefan Pilz.;Michael M Hoffmann.;Andreas Tomaschitz.;Niku Oksala.;Emma Raitoharju.;Leo-Pekka Lyytikäinen.;Kari-Matti Mäkelä.;Reijo Laaksonen.;Mika Kähönen.;Olli T Raitakari.;Jie Huang.;Katharina Kienreich.;Astrid Fahrleitner-Pammer.;Christiane Drechsler.;Vera Krane.;Bernhard O Boehm.;Wolfgang Koenig.;Christoph Wanner.;Terho Lehtimäki.;Winfried März.;Andreas Meinitzer.
来源: Circ Cardiovasc Genet. 2013年6卷5期505-13页
Low serum levels of the amino acid derivative, homoarginine, have been associated with increased risk of total and cardiovascular mortality. Homoarginine deficiency may be related to renal and heart diseases, but the pathophysiologic role of homoarginine and the genetic regulation of its serum levels are largely unknown.
326. A variant in LDLR is associated with abdominal aortic aneurysm.
作者: Declan T Bradley.;Anne E Hughes.;Stephen A Badger.;Gregory T Jones.;Seamus C Harrison.;Benjamin J Wright.;Suzannah Bumpstead.;Annette F Baas.;Sólveig Grétarsdóttir.;Kevin Burnand.;Anne H Child.;Rachel E Clough.;Gillian Cockerill.;Hany Hafez.;D Julian A Scott.;Robert A S Ariëns.;Anne Johnson.;Soroush Sohrabi.;Alberto Smith.;Matthew M Thompson.;Frank M van Bockxmeer.;Matthew Waltham.;Stefán E Matthíasson.;Gudmar Thorleifsson.;Unnur Thorsteinsdottir.;Jan D Blankensteijn.;Joep A W Teijink.;Cisca Wijmenga.;Jacqueline de Graaf.;Lambertus A Kiemeney.;John B Wild.;Sarah Edkins.;Rhian Gwilliam.;Sarah E Hunt.;Simon Potter.;Jes S Lindholt.;Jonathan Golledge.;Paul E Norman.;Andre van Rij.;Janet T Powell.;Per Eriksson.;Kári Stefánsson.;John R Thompson.;Steve E Humphries.;Robert D Sayers.;Panos Deloukas.;Nilesh J Samani.;Matthew J Bown.
来源: Circ Cardiovasc Genet. 2013年6卷5期498-504页
Abdominal aortic aneurysm (AAA) is a common cardiovascular disease among older people and demonstrates significant heritability. In contrast to similar complex diseases, relatively few genetic associations with AAA have been confirmed. We reanalyzed our genome-wide study and carried through to replication suggestive discovery associations at a lower level of significance.
327. Early dual versus mono antiplatelet therapy for acute non-cardioembolic ischemic stroke or transient ischemic attack: an updated systematic review and meta-analysis.
作者: Ka Sing Lawrence Wong.;Yilong Wang.;Xinyi Leng.;Chen Mao.;Jinling Tang.;Philip M W Bath.;Hugh S Markus.;Philip B Gorelick.;Liping Liu.;Wenhua Lin.;Yongjun Wang.
来源: Circulation. 2013年128卷15期1656-66页
Emerging studies suggest that early administration of dual antiplatelet therapy may be better than monotherapy for prevention of early recurrent stroke and cardiovascular outcomes in acute ischemic stroke and transient ischemic attack (TIA). We performed a meta-analysis of randomized, controlled trials evaluating dual versus mono antiplatelet therapy for acute noncardioembolic ischemic stroke or TIA.
328. Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.
作者: Maria Sabater-Lleal.;Jie Huang.;Daniel Chasman.;Silvia Naitza.;Abbas Dehghan.;Andrew D Johnson.;Alexander Teumer.;Alex P Reiner.;Lasse Folkersen.;Saonli Basu.;Alicja R Rudnicka.;Stella Trompet.;Anders Mälarstig.;Jens Baumert.;Joshua C Bis.;Xiuqing Guo.;Jouke J Hottenga.;So-Youn Shin.;Lorna M Lopez.;Jari Lahti.;Toshiko Tanaka.;Lisa R Yanek.;Tiphaine Oudot-Mellakh.;James F Wilson.;Pau Navarro.;Jennifer E Huffman.;Tatijana Zemunik.;Susan Redline.;Reena Mehra.;Drazen Pulanic.;Igor Rudan.;Alan F Wright.;Ivana Kolcic.;Ozren Polasek.;Sarah H Wild.;Harry Campbell.;J David Curb.;Robert Wallace.;Simin Liu.;Charles B Eaton.;Diane M Becker.;Lewis C Becker.;Stefania Bandinelli.;Katri Räikkönen.;Elisabeth Widen.;Aarno Palotie.;Myriam Fornage.;David Green.;Myron Gross.;Gail Davies.;Sarah E Harris.;David C Liewald.;John M Starr.;Frances M K Williams.;Peter J Grant.;Timothy D Spector.;Rona J Strawbridge.;Angela Silveira.;Bengt Sennblad.;Fernando Rivadeneira.;Andre G Uitterlinden.;Oscar H Franco.;Albert Hofman.;Jenny van Dongen.;Gonneke Willemsen.;Dorret I Boomsma.;Jie Yao.;Nancy Swords Jenny.;Talin Haritunians.;Barbara McKnight.;Thomas Lumley.;Kent D Taylor.;Jerome I Rotter.;Bruce M Psaty.;Annette Peters.;Christian Gieger.;Thomas Illig.;Anne Grotevendt.;Georg Homuth.;Henry Völzke.;Thomas Kocher.;Anuj Goel.;Maria Grazia Franzosi.;Udo Seedorf.;Robert Clarke.;Maristella Steri.;Kirill V Tarasov.;Serena Sanna.;David Schlessinger.;David J Stott.;Naveed Sattar.;Brendan M Buckley.;Ann Rumley.;Gordon D Lowe.;Wendy L McArdle.;Ming-Huei Chen.;Geoffrey H Tofler.;Jaejoon Song.;Eric Boerwinkle.;Aaron R Folsom.;Lynda M Rose.;Anders Franco-Cereceda.;Martina Teichert.;M Arfan Ikram.;Thomas H Mosley.;Steve Bevan.;Martin Dichgans.;Peter M Rothwell.;Cathie L M Sudlow.;Jemma C Hopewell.;John C Chambers.;Danish Saleheen.;Jaspal S Kooner.;John Danesh.;Christopher P Nelson.;Jeanette Erdmann.;Muredach P Reilly.;Sekar Kathiresan.;Heribert Schunkert.;Pierre-Emmanuel Morange.;Luigi Ferrucci.;Johan G Eriksson.;David Jacobs.;Ian J Deary.;Nicole Soranzo.;Jacqueline C M Witteman.;Eco J C de Geus.;Russell P Tracy.;Caroline Hayward.;Wolfgang Koenig.;Francesco Cucca.;J Wouter Jukema.;Per Eriksson.;Sudha Seshadri.;Hugh S Markus.;Hugh Watkins.;Nilesh J Samani.; .; .; .; .; .;Henri Wallaschofski.;Nicholas L Smith.;David Tregouet.;Paul M Ridker.;Weihong Tang.;David P Strachan.;Anders Hamsten.;Christopher J O'Donnell.
来源: Circulation. 2013年128卷12期1310-24页
Estimates of the heritability of plasma fibrinogen concentration, an established predictor of cardiovascular disease, range from 34% to 50%. Genetic variants so far identified by genome-wide association studies explain only a small proportion (<2%) of its variation.
329. Levels and changes of HDL cholesterol and apolipoprotein A-I in relation to risk of cardiovascular events among statin-treated patients: a meta-analysis.
作者: S Matthijs Boekholdt.;Benoit J Arsenault.;G Kees Hovingh.;Samia Mora.;Terje R Pedersen.;John C Larosa.;K M A Welch.;Pierre Amarenco.;David A Demicco.;Andrew M Tonkin.;David R Sullivan.;Adrienne Kirby.;Helen M Colhoun.;Graham A Hitman.;D John Betteridge.;Paul N Durrington.;Michael B Clearfield.;John R Downs.;Antonio M Gotto.;Paul M Ridker.;John J P Kastelein.
来源: Circulation. 2013年128卷14期1504-12页
It is unclear whether levels of high-density lipoprotein cholesterol (HDL-C) or apolipoprotein A-I (apoA-I) remain inversely associated with cardiovascular risk among patients who achieve very low levels of low-density lipoprotein cholesterol on statin therapy. It is also unknown whether a rise in HDL-C or apoA-I after initiation of statin therapy is associated with a reduced cardiovascular risk.
332. Association between C677T polymorphism of methylene tetrahydrofolate reductase and congenital heart disease: meta-analysis of 7697 cases and 13,125 controls.
作者: Chrysovalanto Mamasoula.;R Reid Prentice.;Tomasz Pierscionek.;Faith Pangilinan.;James L Mills.;Charlotte Druschel.;Kenneth Pass.;Mark W Russell.;Darroch Hall.;Ana Töpf.;Danielle L Brown.;Diana Zelenika.;Jamie Bentham.;Catherine Cosgrove.;Shoumo Bhattacharya.;Javier Granados Riveron.;Kerry Setchfield.;J David Brook.;Frances A Bu'Lock.;Chris Thornborough.;Thahira J Rahman.;Julian Palomino Doza.;Huay L Tan.;John O'Sullivan.;A Graham Stuart.;Gillian Blue.;David Winlaw.;Alex V Postma.;Barbara J M Mulder.;Aelko H Zwinderman.;Klaartje van Engelen.;Antoon F M Moorman.;Anita Rauch.;Marc Gewillig.;Jeroen Breckpot.;Koen Devriendt.;G Mark Lathrop.;Martin Farrall.;Judith A Goodship.;Heather J Cordell.;Lawrence C Brody.;Bernard D Keavney.
来源: Circ Cardiovasc Genet. 2013年6卷4期347-53页
Association between the C677T polymorphism of the methylene tetrahydrofolate reductase (MTHFR) gene and congenital heart disease (CHD) is contentious.
333. Identification of a KCNQ1 polymorphism acting as a protective modifier against arrhythmic risk in long-QT syndrome.
作者: Sabine Duchatelet.;Lia Crotti.;Rachel A Peat.;Isabelle Denjoy.;Hideki Itoh.;Myriam Berthet.;Seiko Ohno.;Véronique Fressart.;Maria Cristina Monti.;Cristina Crocamo.;Matteo Pedrazzini.;Federica Dagradi.;Alessandro Vicentini.;Didier Klug.;Paul A Brink.;Althea Goosen.;Heikki Swan.;Lauri Toivonen.;Annukka M Lahtinen.;Kimmo Kontula.;Wataru Shimizu.;Minoru Horie.;Alfred L George.;David-Alexandre Trégouët.;Pascale Guicheney.;Peter J Schwartz.
来源: Circ Cardiovasc Genet. 2013年6卷4期354-61页
Long-QT syndrome (LQTS) is characterized by such striking clinical heterogeneity that, even among family members carrying the same mutation, clinical outcome can range between sudden death and no symptoms. We investigated the role of genetic variants as modifiers of risk for cardiac events in patients with LQTS.
334. Stratified meta-analysis of intermittent pneumatic compression of the lower limbs to prevent venous thromboembolism in hospitalized patients.
Optimal thromboprophylaxis for patients at risk of bleeding remains uncertain. This meta-analysis assessed whether intermittent pneumatic compression (IPC) of the lower limbs was effective in reducing venous thromboembolism and whether combining pharmacological thromboprophylaxis with IPC would enhance its effectiveness.
335. Comparative tolerability and harms of individual statins: a study-level network meta-analysis of 246 955 participants from 135 randomized, controlled trials.
Our objective was to estimate the comparative harms of individual statins using both placebo-controlled and active-comparator trials.
336. Combined effects of child and adult elevated blood pressure on subclinical atherosclerosis: the International Childhood Cardiovascular Cohort Consortium.
作者: Jonna Juhola.;Costan G Magnussen.;Gerald S Berenson.;Alison Venn.;Trudy L Burns.;Matthew A Sabin.;Sathanur R Srinivasan.;Stephen R Daniels.;Patricia H Davis.;Wei Chen.;Mika Kähönen.;Leena Taittonen.;Elaine Urbina.;Jorma S A Viikari.;Terence Dwyer.;Olli T Raitakari.;Markus Juonala.
来源: Circulation. 2013年128卷3期217-24页
Elevated blood pressure (BP) levels in childhood have been associated with subsequent atherosclerosis. However, it is uncertain whether this risk is attenuated in individuals who acquire normal BP by adulthood. The present study examined the effect of child and adult BP levels on carotid artery intima-media thickness (IMT) in adulthood.
337. The prognostic value of normal stress cardiac magnetic resonance in patients with known or suspected coronary artery disease: a meta-analysis.
作者: Paola Gargiulo.;Santo Dellegrottaglie.;Dario Bruzzese.;Gianluigi Savarese.;Oriana Scala.;Donatella Ruggiero.;Carmen D'Amore.;Stefania Paolillo.;Piergiuseppe Agostoni.;Edoardo Bossone.;Andrea Soricelli.;Alberto Cuocolo.;Bruno Trimarco.;Pasquale Perrone Filardi.
来源: Circ Cardiovasc Imaging. 2013年6卷4期574-82页
Ischemia detection with stress cardiac magnetic resonance (CMR) is typically based on induction of either myocardial perfusion defect or wall motion abnormality. Single-center studies have shown the high value of stress CMR for risk stratification. The aim of this study was to define the prognostic value of stress CMR for prediction of adverse cardiac events in patients with known or suspected coronary artery disease.
338. Validation and prognosis of coronary artery calcium scoring in nontriggered thoracic computed tomography: systematic review and meta-analysis.
作者: Xueqian Xie.;Yingru Zhao.;Geertruida H de Bock.;Pim A de Jong.;Willem P Mali.;Matthijs Oudkerk.;Rozemarijn Vliegenthart.
来源: Circ Cardiovasc Imaging. 2013年6卷4期514-21页
Coronary calcium score (CS), traditionally based on electrocardiography-triggered computed tomography (CT), predicts cardiovascular risk. Currently, nontriggered thoracic CT is extensively used, such as in lung cancer screening. The purpose of the study was to determine the correlation in CS between nontriggered and electrocardiography-triggered CT, and to evaluate the prognostic performance of the CS derived from nontriggered CT.
339. Bayesian methods affirm the use of percutaneous coronary intervention to improve survival in patients with unprotected left main coronary artery disease.
作者: John A Bittl.;Yulei He.;Alice K Jacobs.;Clyde W Yancy.;Sharon-Lise T Normand.; .
来源: Circulation. 2013年127卷22期2177-85页
Several randomized clinical trials support the use of coronary artery bypass grafting (CABG) for patients with unprotected left main coronary artery disease. Studies suggesting the equivalence of percutaneous coronary intervention (PCI) with CABG for this indication indirectly support the 2011 American College of Cardiology Foundation/American Heart Association Class IIa recommendation for PCI to improve survival in patients with unprotected left main coronary artery disease. We tested whether bayesian approaches uphold the new recommendation.
340. Implantable cardioverter defibrillators in arrhythmogenic right ventricular dysplasia/cardiomyopathy: patient outcomes, incidence of appropriate and inappropriate interventions, and complications.
Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is a cardiomyopathy characterized by ventricular arrhythmias and an abnormal right ventricle. Implantable cardioverter defibrillator (ICD) therapy may prevent sudden cardiac death in patients with ARVD/C. Currently, an overview of outcomes, appropriate and inappropriate interventions, and complications of ICD therapy in ARVD/C is lacking.
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