301. Development and Evaluation of a Comprehensive Prediction Model for Incident Coronary Heart Disease Using Genetic, Social, and Lifestyle-Psychological Factors: A Prospective Analysis of the UK Biobank.
作者: Mohammadreza Naderian.;Kristjan Norland.;Daniel J Schaid.;Iftikhar J Kullo.
来源: Ann Intern Med. 2025年178卷1期1-10页
Clinical risk calculators for coronary heart disease (CHD) do not include genetic, social, and lifestyle-psychological risk factors.
308. The Effect of the "Safety in Dementia" Online Tool to Assist Decision Making for Caregivers of Persons With Dementia and Access to Firearms : A Randomized Trial.
作者: Marian E Betz.;Jennifer Portz.;Christopher Knoepke.;Megan L Ranney.;Stacy M Fischer.;Ryan A Peterson.;Rachel L Johnson.;Faris Omeragic.;Mirella Castaneda.;Emily Greenway.;Daniel Matlock.
来源: Ann Intern Med. 2024年177卷12期1630-1640页
Caregivers face challenges (including competing desires to prevent injury, respect autonomy, and avoid conflict) when addressing firearm access by community-dwelling persons with Alzheimer disease and related dementias (ADRD).
314. In older adults receiving high-risk medications, a deprescribing intervention did not reduce falls at 18 mo.
Phelan EA, Williamson BD, Balderson BH, et al. Reducing central nervous system-active medications to prevent falls and injuries among older adults: a cluster randomized clinical trial. JAMA Netw Open. 2024;7:e2424234. 39052289.
315. In older inpatients with polypharmacy, medication optimization did not improve outcomes at 48 wk.
Ie K, Hirose M, Sakai T, et al. Medication optimization protocol efficacy for geriatric inpatients: a randomized clinical trial. JAMA Netw Open. 2024;7:e2423544. 39078632.
318. Risk for Financial Precarity From Hospitalization: Implications for Targeting Financial Assistance in Medicare.
作者: Paula Chatterjee.;Eliza Macneal.;Syama R Patel.;Eric T Roberts.
来源: Ann Intern Med. 2024年177卷12期1601-1609页
High out-of-pocket costs in Medicare may leave many beneficiaries in financial precarity. Beneficiaries with modest incomes are often ineligible for Medicaid (which covers most out-of-pocket Medicare costs) and may have insufficient resources to pay an unexpected health care bill. This has prompted calls to improve financial protections, but the target population remains uncharacterized.
320. Projected Impact and Cost-Effectiveness of Novel Molecular Blood-Based or Stool-Based Screening Tests for Colorectal Cancer.
作者: Uri Ladabaum.;Ajitha Mannalithara.;Robert E Schoen.;Jason A Dominitz.;David Lieberman.
来源: Ann Intern Med. 2024年177卷12期1610-1620页
Cell-free DNA blood tests (cf-bDNA) and next-generation stool tests could change colorectal cancer (CRC) screening.
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