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261. Treatment of primary Sjögren syndrome with rituximab: a randomized trial.
作者: Valérie Devauchelle-Pensec.;Xavier Mariette.;Sandrine Jousse-Joulin.;Jean-Marie Berthelot.;Aleth Perdriger.;Xavier Puéchal.;Véronique Le Guern.;Jean Sibilia.;Jacques-Eric Gottenberg.;Laurent Chiche.;Eric Hachulla.;Pierre Yves Hatron.;Vincent Goeb.;Gilles Hayem.;Jacques Morel.;Charles Zarnitsky.;Jean Jacques Dubost.;Jacques Olivier Pers.;Emmanuel Nowak.;Alain Saraux.
来源: Ann Intern Med. 2014年160卷4期233-42页
Primary Sjögren syndrome (pSS) is an autoimmune disorder characterized by ocular and oral dryness or systemic manifestations.
262. Prevention of diabetes with Mediterranean diets: a subgroup analysis of a randomized trial.
作者: Jordi Salas-Salvadó.;Mònica Bulló.;Ramón Estruch.;Emilio Ros.;Maria-Isabel Covas.;Núria Ibarrola-Jurado.;Dolores Corella.;Fernando Arós.;Enrique Gómez-Gracia.;Valentina Ruiz-Gutiérrez.;Dora Romaguera.;José Lapetra.;Rosa Maria Lamuela-Raventós.;Lluís Serra-Majem.;Xavier Pintó.;Josep Basora.;Miguel Angel Muñoz.;José V Sorlí.;Miguel A Martínez-González.
来源: Ann Intern Med. 2014年160卷1期1-10页
Interventions promoting weight loss can reduce the incidence of type 2 diabetes mellitus. Whether dietary changes without calorie restriction also protect from diabetes has not been evaluated.
263. Doxycycline for stabilization of abdominal aortic aneurysms: a randomized trial.
作者: C Arnoud Meijer.;Theo Stijnen.;Martin N J M Wasser.;Jaap F Hamming.;J Hajo van Bockel.;Jan H N Lindeman.; .
来源: Ann Intern Med. 2013年159卷12期815-23页
Doxycycline inhibits formation and progression of abdominal aortic aneurysms (AAAs) in preclinical models of the disease, but it is unclear whether and how this observation translates to humans.
264. Long-term multivitamin supplementation and cognitive function in men: a randomized trial.
作者: Francine Grodstein.;Jacqueline O'Brien.;Jae Hee Kang.;Rimma Dushkes.;Nancy R Cook.;Olivia Okereke.;JoAnn E Manson.;Robert J Glynn.;Julie E Buring.;Michael Gaziano.;Howard D Sesso.
来源: Ann Intern Med. 2013年159卷12期806-14页
Despite widespread use of multivitamin supplements, their effect on cognitive health-a critical issue with aging-remains inconclusive. To date, no long-term clinical trials have studied multivitamin use and cognitive decline in older persons.
265. Oral high-dose multivitamins and minerals after myocardial infarction: a randomized trial.
作者: Gervasio A Lamas.;Robin Boineau.;Christine Goertz.;Daniel B Mark.;Yves Rosenberg.;Mario Stylianou.;Theodore Rozema.;Richard L Nahin.;Lauren Lindblad.;Eldrin F Lewis.;Jeanne Drisko.;Kerry L Lee.; .
来源: Ann Intern Med. 2013年159卷12期797-805页
Whether high-dose multivitamins are effective for secondary prevention of atherosclerotic disease is unknown.
266. Pegylated interferon-α2a with or without low-dose ribavirin for treatment-naive patients with hepatitis C virus genotype 1 receiving hemodialysis: a randomized trial.
作者: Chen-Hua Liu.;Chung-Feng Huang.;Chun-Jen Liu.;Chia-Yen Dai.;Cheng-Chao Liang.;Jee-Fu Huang.;Peir-Haur Hung.;Hung-Bin Tsai.;Meng-Kun Tsai.;Shih-I Chen.;Jou-Wei Lin.;Sheng-Shun Yang.;Tung-Hung Su.;Hung-Chih Yang.;Pei-Jer Chen.;Ding-Shinn Chen.;Wan-Long Chuang.;Ming-Lung Yu.;Jia-Horng Kao.
来源: Ann Intern Med. 2013年159卷11期729-38页
Data are limited on the efficacy and safety of pegylated interferon plus ribavirin for patients with hepatitis C virus genotype 1 (HCV-1) receiving hemodialysis.
267. Albumin dialysis with a noncell artificial liver support device in patients with acute liver failure: a randomized, controlled trial.
作者: Faouzi Saliba.;Christophe Camus.;François Durand.;Philippe Mathurin.;Alexia Letierce.;Bertrand Delafosse.;Karl Barange.;Pierre François Perrigault.;Magali Belnard.;Philippe Ichaï.;Didier Samuel.
来源: Ann Intern Med. 2013年159卷8期522-31页
Albumin dialysis with the Molecular Adsorbent Recirculating System (MARS) (Gambro, Lund, Sweden), a noncell artificial liver support device, may be beneficial in acute liver failure (ALF).
268. Effects of varenicline on smoking cessation in adults with stably treated current or past major depression: a randomized trial.
作者: Robert M Anthenelli.;Chad Morris.;Tanya S Ramey.;Sarah J Dubrava.;Kostas Tsilkos.;Cristina Russ.;Carla Yunis.
来源: Ann Intern Med. 2013年159卷6期390-400页
Chinese translation
269. Social networking technologies as an emerging tool for HIV prevention: a cluster randomized trial.
作者: Sean D Young.;William G Cumberland.;Sung-Jae Lee.;Devan Jaganath.;Greg Szekeres.;Thomas Coates.
来源: Ann Intern Med. 2013年159卷5期318-24页
Social networking technologies are an emerging tool for HIV prevention.
270. Methylprednisolone injections for the carpal tunnel syndrome: a randomized, placebo-controlled trial.
作者: Isam Atroshi.;Magnus Flondell.;Manfred Hofer.;Jonas Ranstam.
来源: Ann Intern Med. 2013年159卷5期309-17页
Steroid injections are used in idiopathic carpal tunnel syndrome (CTS), but evidence of efficacy beyond 1 month is lacking.
271. Tofacitinib in combination with nonbiologic disease-modifying antirheumatic drugs in patients with active rheumatoid arthritis: a randomized trial.
作者: Joel Kremer.;Zhan-Guo Li.;Stephen Hall.;Roy Fleischmann.;Mark Genovese.;Emilio Martin-Mola.;John D Isaacs.;David Gruben.;Gene Wallenstein.;Sriram Krishnaswami.;Samuel H Zwillich.;Tamas Koncz.;Richard Riese.;John Bradley.
来源: Ann Intern Med. 2013年159卷4期253-61页
Many patients with rheumatoid arthritis (RA) do not achieve adequate and safe responses with disease-modifying antirheumatic drugs (DMARDs). Tofacitinib is a novel, oral, Janus kinase inhibitor that treats RA.
272. A home-based intervention to reduce depressive symptoms and improve quality of life in older African Americans: a randomized trial.
作者: Laura N Gitlin.;Lynn Fields Harris.;Megan C McCoy.;Nancy L Chernett.;Laura T Pizzi.;Eric Jutkowitz.;Edward Hess.;Walter W Hauck.
来源: Ann Intern Med. 2013年159卷4期243-52页
Effective care models for treating older African Americans with depressive symptoms are needed.
273. Improving chronic disease care by adding laypersons to the primary care team: a parallel randomized trial.
作者: Richard Adair.;Douglas R Wholey.;Jon Christianson.;Katie M White.;Heather Britt.;Suhna Lee.
来源: Ann Intern Med. 2013年159卷3期176-84页
Improving the quality and efficiency of chronic disease care is an important goal.
274. Salicylate (salsalate) in patients with type 2 diabetes: a randomized trial.
作者: Allison B Goldfine.;Vivian Fonseca.;Kathleen A Jablonski.;Yii-Der Ida Chen.;Laura Tipton.;Myrlene A Staten.;Steven E Shoelson.; .
来源: Ann Intern Med. 2013年159卷1期1-12页
Short-duration studies show that salsalate improves glycemia in type 2 diabetes mellitus (T2DM).
275. Clinical outcomes with rivaroxaban in patients transitioned from vitamin K antagonist therapy: a subgroup analysis of a randomized trial.
作者: Kenneth W Mahaffey.;Daniel Wojdyla.;Graeme J Hankey.;Harvey D White.;Christopher C Nessel.;Jonathan P Piccini.;Manesh R Patel.;Scott D Berkowitz.;Richard C Becker.;Jonathan L Halperin.;Daniel E Singer.;Robert M Califf.;Keith A A Fox.;Günter Breithardt.;Werner Hacke.
来源: Ann Intern Med. 2013年158卷12期861-8页
In ROCKET AF (Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation), a large randomized, clinical trial, rivaroxaban was noninferior to warfarin in preventing stroke or systemic embolism in patients with atrial fibrillation.
276. Aspirin versus low-molecular-weight heparin for extended venous thromboembolism prophylaxis after total hip arthroplasty: a randomized trial.
作者: David R Anderson.;Michael J Dunbar.;Eric R Bohm.;Etienne Belzile.;Susan R Kahn.;David Zukor.;William Fisher.;Wade Gofton.;Peter Gross.;Stephane Pelet.;Mark Crowther.;Steven MacDonald.;Paul Kim.;Susan Pleasance.;Nicki Davis.;Pantelis Andreou.;Philip Wells.;Michael Kovacs.;Marc A Rodger.;Tim Ramsay.;Marc Carrier.;Pascal-Andre Vendittoli.
来源: Ann Intern Med. 2013年158卷11期800-6页
The role of aspirin in thromboprophylaxis after total hip arthroplasty (THA) is controversial.
277. Sunscreen and prevention of skin aging: a randomized trial.
作者: Maria Celia B Hughes.;Gail M Williams.;Peter Baker.;Adèle C Green.
来源: Ann Intern Med. 2013年158卷11期781-90页
Sunscreen use and dietary antioxidants are advocated as preventives of skin aging, but supporting evidence is lacking.
278. The effect of oxandrolone on the healing of chronic pressure ulcers in persons with spinal cord injury: a randomized trial.
作者: William A Bauman.;Ann M Spungen.;Joseph F Collins.;Dennis W Raisch.;Chester Ho.;George A Deitrick.;Bernard A Nemchausky.;Lance L Goetz.;Jai S Park.;Michael Schwartz.;John L Merritt.;Vidya Jayawardena.;Paul Sandford.;Sunil Sabharwal.;Sally A Holmes.;Fahima Nasar.;Roy Sasaki.;Vandana Punj.;Karin F Zachow.;Walter C Chua.;MaryKutty D Thomas.;Rose C Trincher.
来源: Ann Intern Med. 2013年158卷10期718-26页
Anabolic steroids have been reported to improve wound healing.
279. Combination therapy with telaprevir for chronic hepatitis C virus genotype 1 infection in patients with HIV: a randomized trial.
作者: Mark S Sulkowski.;Kenneth E Sherman.;Douglas T Dieterich.;Mohammad Bsharat.;Lisa Mahnke.;Jürgen K Rockstroh.;Shahin Gharakhanian.;Scott McCallister.;Joshua Henshaw.;Pierre-Marie Girard.;Bambang Adiwijaya.;Varun Garg.;Raymond A Rubin.;Nathalie Adda.;Vincent Soriano.
来源: Ann Intern Med. 2013年159卷2期86-96页
Telaprevir (TVR) plus peginterferon-α2a (PEG-IFN-α2a) and ribavirin substantially increases treatment efficacy for genotype 1 chronic hepatitis C virus (HCV) infection versus PEG-IFN-α2a-ribavirin alone. Its safety and efficacy in patients with HCV and HIV-1 are unknown.
280. Action to stop smoking in suspected tuberculosis (ASSIST) in Pakistan: a cluster randomized, controlled trial.
作者: Kamran Siddiqi.;Amir Khan.;Maqsood Ahmad.;Omara Dogar.;Mona Kanaan.;James N Newell.;Heather Thomson.
来源: Ann Intern Med. 2013年158卷9期667-75页
Tobacco use is responsible for a large proportion of the total disease burden from tuberculosis. Pakistan is one of the 10 high-burden countries for both tuberculosis and tobacco use.
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