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2021. Prolonged Prone Position Ventilation Is Associated With Reduced Mortality in Intubated COVID-19 Patients.
作者: Daniel Okin.;Ching-Ying Huang.;George A Alba.;Sirus J Jesudasen.;Nupur A Dandawate.;Alexander Gavralidis.;Leslie L Chang.;Emily E Moin.;Imama Ahmad.;Alison S Witkin.;C Corey Hardin.;Kathryn A Hibbert.;Aran Kadar.;Patrick L Gordan.;Hang Lee.;B Taylor Thompson.;Lisa M Bebell.;Peggy S Lai.
来源: Chest. 2023年163卷3期533-542页
Prone position ventilation (PPV) is resource-intensive, yet the optimal strategy for PPV in intubated patients with COVID-19 is unclear.
2022. Consensus Statements on Deployment-Related Respiratory Disease, Inclusive of Constrictive Bronchiolitis: A Modified Delphi Study.
作者: Michael J Falvo.;Anays M Sotolongo.;John J Osterholzer.;Michelle W Robertson.;Ella A Kazerooni.;Judith K Amorosa.;Eric Garshick.;Kirk D Jones.;Jeffrey R Galvin.;Kathleen Kreiss.;Stella E Hines.;Teri J Franks.;Robert F Miller.;Cecile S Rose.;Mehrdad Arjomandi.;Silpa D Krefft.;Michael J Morris.;Vasiliy V Polosukhin.;Paul D Blanc.;Jeanine M D'Armiento.
来源: Chest. 2023年163卷3期599-609页
The diagnosis of constrictive bronchiolitis (CB) in previously deployed individuals, and evaluation of respiratory symptoms more broadly, presents considerable challenges, including using consistent histopathologic criteria and clinical assessments.
2023. Association Between Shared Decision-Making During Family Meetings and Surrogates' Trust in Their ICU Physician.
作者: Taylor E Lincoln.;Praewpannarai Buddadhumaruk.;Robert M Arnold.;Leslie P Scheunemann.;Natalie C Ernecoff.;Chung-Chou H Chang.;Shannon S Carson.;Catherine L Hough.;J Randall Curtis.;Wendy Anderson.;Jay Steingrub.;Michael W Peterson.;Bernard Lo.;Michael A Matthay.;Douglas B White.
来源: Chest. 2023年163卷5期1214-1224页
Although trust is central to successful physician-family relationships in ICUs, little is known about how to promote surrogates' trust of ICU physicians in this setting.
2024. Comparative Effectiveness of Amiodarone and Lidocaine for the Treatment of In-Hospital Cardiac Arrest.
作者: Deborah Wagner.;S L Kronick.;H Nawer.;J A Cranford.;S M Bradley.;R W Neumar.
来源: Chest. 2023年163卷5期1109-1119页
American Heart Association Advanced Cardiac Life Support (ACLS) guidelines support the use of either amiodarone or lidocaine for cardiac arrest caused by ventricular tachycardia or ventricular fibrillation (VT/VF) based on studies of out-of-hospital cardiac arrest. Studies comparing amiodarone and lidocaine in adult populations with in-hospital VT/VF arrest are lacking.
2025. Developing Fractional Exhaled Nitric Oxide Predicted and Upper Limit of Normal Values for a Disadvantaged Population.
作者: Andrew J Collaro.;Anne B Chang.;Julie M Marchant.;Don Vicendese.;Mark D Chatfield.;Johanna F Cole.;Tamara L Blake.;Margaret S McElrea.
来源: Chest. 2023年163卷3期624-633页
Fractional exhaled nitric oxide (Feno), used as a biomarker, is influenced by several factors including ethnicity. Normative data are essential for interpretation, and currently single cutoff values are used in children and adults.
2026. Tranexamic Acid vs Adrenaline for Controlling Iatrogenic Bleeding During Flexible Bronchoscopy: A Double-Blind Randomized Controlled Trial.
作者: Sonja Badovinac.;Goran Glodić.;Ivan Sabol.;Feđa Džubur.;Mateja Janković Makek.;Denis Baričević.;Marta Koršić.;Filip Popović.;Dražena Srdić.;Miroslav Samaržija.
来源: Chest. 2023年163卷4期985-993页
The most commonly used topical hemostatic agents during flexible bronchoscopy (FB) are cold saline and adrenaline. Data on use of other agents such as tranexamic acid (TXA) for this purpose are limited.
2027. Pleuropulmonary Manifestations of Vacuoles, E1 Enzyme, X-Linked, Autoinflammatory, Somatic (VEXAS) Syndrome.
作者: Raphael Borie.;Marie Pierre Debray.;Alexis F Guedon.;Arsene Mekinian.;Louis Terriou.;Valentin Lacombe.;Estibaliz Lazaro.;Aurore Meyer.;Alexis Mathian.;Samuel Ardois.;Guillaume Vial.;Thomas Moulinet.;Benjamin Terrier.;Yvan Jamilloux.;Mael Heiblig.;Jean-David Bouaziz.;Eve Zakine.;Roderau Outh.;Sylvie Groslerons.;Adrien Bigot.;Edouard Flamarion.;Marie Kostine.;Pierrick Henneton.;Sebastien Humbert.;Arnaud Constantin.;Maxime Samson.;Nadine Magy Bertrand.;Pascal Biscay.;Celine Dieval.;Herve Lobbes.;Juliette Jeannel.;Amelie Servettaz.;Leo Adelaide.;Julie Graveleau.;Benjamin de Sainte-Marie.;Joris Galland.;Vivien Guillotin.;Eugénie Duroyon.;Marie Templé.;Rim Bourguiba.;Sophie Georgin Lavialle.;Olivier Kosmider.;Alexandra Audemard-Verger.; .
来源: Chest. 2023年163卷3期575-585页
The vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome is a newly identified autoinflammatory disorder related to somatic UBA1 mutations. Up to 72% of patients may show lung involvement.
2028. Ventilatory Parameters in Obstetric Patients With COVID-19 and Impact of Delivery: A Multicenter Prospective Cohort Study.
作者: Daniela N Vasquez.;Roberto Giannoni.;Adriana Salvatierra.;Karina Cisneros.;Diego Lafosse.;María F Escobar.;Martín Montenegro.;Paula Juárez.;Lucía Visani.;Verónica Mandich.;Erika Barrozo.;Mariana Kirschbaum.;Andrea V Das Neves.;María F Valenti.;María C Canseco.;Ignacio Romero.;Pedro Macharé.;Ana K Marquez.;Eva Rodriguez.;Cristina Palacio.;Laura Rapela.;José M Amillategui Scenna.;Rosshanna Nuñez.;Sebastián Torres.;Miguel A González.;Lorena Franconieri.;Daniela Nasner.;Patricia Okurzaty.;Gustavo A Plotnikow.;Alfredo D Intile.
来源: Chest. 2023年163卷3期554-566页
Current evidence on obstetric patients requiring advanced ventilatory support and impact of delivery on ventilatory parameters is retrospective, scarce, and controversial.
2029. Providing End-of-Life Care for Patients Dying of COVID-19 and Their Families in Isolated Death During the Pandemic in Japan: The Providing End-of-life Care for COVID-19 Project.
作者: Mayumi Nishimura.;Mayumi Toyama.;Hiroko Mori.;Makiko Sano.;Haruki Imura.;Akira Kuriyama.;Takeo Nakayama.
来源: Chest. 2023年163卷2期383-395页
Death resulting from COVID-19 in a hospital during the pandemic has meant death in isolation. Although many health care providers (HCPs) have struggled with end-of-life (EOL) care for these patients, the various strategies across hospitals are not well known.
2030. Days Spent at Home and Mortality After Critical Illness: A Cluster Analysis Using Nationwide Data.
作者: Guillaume L Martin.;Alice Atramont.;Marjorie Mazars.;Ayden Tajahmady.;Emin Agamaliyev.;Mervyn Singer.;Marc Leone.;Matthieu Legrand.
来源: Chest. 2023年163卷4期826-842页
Beyond the question of short-term survival, days spent at home could be considered a patient-centered outcome in critical care trials.
2032. Sleep Arousal-Related Ventricular Repolarization Lability Is Associated With Cardiovascular Mortality in Older Community-Dwelling Men.
作者: Sobhan Salari Shahrbabaki.;Dominik Linz.;Susan Redline.;Katie Stone.;Kristine Ensrud.;Mathias Baumert.
来源: Chest. 2023年163卷2期419-432页
Sleep is fragmented by brief arousals, and excessive arousal burden has been linked to increased cardiovascular (CV) risk, but mechanisms are poorly understood.
2033. Cohort Enrichment Strategies for Progressive Interstitial Lung Disease in Systemic Sclerosis From European Scleroderma Trials and Research.
作者: Anna-Maria Hoffmann-Vold.;Cathrine Brunborg.;Paolo Airò.;Lidia P Ananyeva.;László Czirják.;Serena Guiducci.;Eric Hachulla.;Mengtao Li.;Carina Mihai.;Gabriela Riemekasten.;Petros P Sfikakis.;Gabriele Valentini.;Otylia Kowal-Bielecka.;Yannick Allanore.;Oliver Distler.; .
来源: Chest. 2023年163卷3期586-598页
Enrichment strategies from clinical trials for progressive systemic sclerosis-associated interstitial lung disease (SSc-ILD) have not been tested in a real-life cohort.
2034. Coordination of Care for Expiratory Central Airway Collapse: A Structured Process for a Multifaceted Disease.
作者: Britney N Hazelett.;Alichia Paton.;Adnan Majid.;Margaret M Johnson.;Neal M Patel.;David Abia-Trujillo.;Alejandra Yu Lee-Mateus.;Anna Kornafeld.;Sebastian Fernandez-Bussy.
来源: Chest. 2023年163卷1期185-191页
Common respiratory symptoms, including dyspnea, cough, sputum production, and recurrent infections, frequently remain without a clear cause and may be the result of expiratory central airway collapse (ECAC). Establishing the diagnosis and appropriate treatment plan for patients with ECAC is challenging and benefits from a multidisciplinary approach. A coordinator role is crucial in this process to ensure optimal patient-centered outcomes. We describe the coordination of care in the process of diagnosing and treating ECAC. The coordinator leads the organization of the multiple services involved in the care of patients with ECAC, including pulmonary medicine, interventional pulmonology, radiology, and thoracic surgery, as well as hospital inpatient staff. From initial screening to evaluation and management with airway stents and corrective treatment with tracheobronchoplasty, the ECAC coordinator oversees the entire process of care for patients with ECAC.
2035. Evidence of Advanced Pulmonary Vascular Remodeling in Obstructive Hypertrophic Cardiomyopathy With Pulmonary Hypertension.
作者: Bradley A Maron.;David E Kleiner.;Elena Arons.;Bradley M Wertheim.;Nirmal S Sharma.;Kathleen J Haley.;Andriy O Samokhin.;Ethan J Rowin.;Martin S Maron.;Douglas R Rosing.;Barry J Maron.
来源: Chest. 2023年163卷3期678-686页
Elevated mean pulmonary artery pressure (mPAP) is common in patients with hypertrophic cardiomyopathy (HCM) and heart failure symptoms. However, dynamic left ventricular (LV) outflow tract obstruction may confound interpretation of pulmonary hypertension (PH) pathophysiologic features in HCM when relying on resting invasive hemodynamic data alone.
2036. Multidisciplinary ICU Recovery Clinic Visits: A Qualitative Analysis of Patient-Provider Dialogues.
作者: Leanne M Boehm.;Valerie Danesh.;Tammy L Eaton.;Joanne McPeake.;Maria A Pena.;Kemberlee R Bonnet.;Joanna L Stollings.;Abigail C Jones.;David G Schlundt.;Carla M Sevin.
来源: Chest. 2023年163卷4期843-854页
Research confirms the heterogeneous nature of patient challenges during recovery from the ICU and supports the need for modifying care experiences, but few data are available to guide clinicians seeking to support patients' individual recovery trajectories.
2037. Diagnosing Non-Small Cell Lung Cancer by Exhaled Breath Profiling Using an Electronic Nose: A Multicenter Validation Study.
作者: Sharina Kort.;Marjolein Brusse-Keizer.;Hugo Schouwink.;Emanuel Citgez.;Frans H de Jongh.;Jan W G van Putten.;Ben van den Borne.;Elisabeth A Kastelijn.;Daiana Stolz.;Milou Schuurbiers.;Michel M van den Heuvel.;Wouter H van Geffen.;Job van der Palen.
来源: Chest. 2023年163卷3期697-706页
Despite the potential of exhaled breath analysis of volatile organic compounds to diagnose lung cancer, clinical implementation has not been realized, partly due to the lack of validation studies.
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