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181. Early-Age Onset Colorectal Neoplasia in Average-Risk Individuals Undergoing Screening Colonoscopy: A Systematic Review and Meta-Analysis.
作者: Jennifer M Kolb.;Junxiao Hu.;Kristen DeSanto.;Dexiang Gao.;Siddharth Singh.;Thomas Imperiale.;David A Lieberman.;C Richard Boland.;Swati G Patel.
来源: Gastroenterology. 2021年161卷4期1145-1155.e12页
Incidence and mortality associated with early-age onset colorectal cancer (EAO-CRC) is increasing, prompting professional society recommendations to lower the screening age in average-risk individuals. The yield of screening individuals younger than 50 years is not known.
182. Correlation between the geographical origin of Helicobacter pylori homB-positive strains and their clinical outcomes: a systematic review and meta-analysis.
In general, all virulence factors of Helicobacter pylori (H. pylori) are involved in its infections. However, recent studies have shown that the homB gene is one of the virulence genes that affects the severity of the clinical results of this bacterium.
183. Robotic versus laparoscopic total mesorectal excision for rectal cancer: a meta-analysis of long-term survival and urogenital functional outcomes.
作者: Xian Li.;Zhen-Hua Liu.;Ning Wang.;Jie Ding.;Fei Fan.;Xiang-Ying Cen.;Ming Wu.;Rui Mi.;Hang Liu.;Yuan-Ling Zhang.
来源: Minerva Gastroenterol (Torino). 2023年69卷3期403-411页
Robotic surgical technology has been widely introduced and applied in various fields of surgery. The aim of this study was to analyze long-term oncological and urogenital functional outcomes following laparoscopic/robotic total mesorectal excision (TME) in rectal cancer surgery.
184. Comparative Effectiveness of Multiple Different First-Line Treatment Regimens for Helicobacter pylori Infection: A Network Meta-analysis.
作者: Theodore Rokkas.;Javier P Gisbert.;Peter Malfertheiner.;Yaron Niv.;Antonio Gasbarrini.;Marcis Leja.;Francis Megraud.;Colm O'Morain.;David Y Graham.
来源: Gastroenterology. 2021年161卷2期495-507.e4页
A number of double, triple, and quadruple therapies have been proposed as first-line empiric treatments for Helicobacter pylori infection. However, knowledge of their worldwide and regional comparative efficacy is lacking. We examined the comparative effectiveness of all empirically used first-line regimens tested against standard triple treatment using a network meta-analysis of published randomized controlled trials.
186. Treatment of acute cholecystitis in high-risk surgical patients.
作者: Andrea Lisotti.;Bertrand Napoleon.;Carlo Fabbri.;Andrea Anderloni.;Romano Linguerri.;Igor Bacchilega.;Pietro Fusaroli.
来源: Minerva Gastroenterol (Torino). 2022年68卷2期154-161页
Acute cholecystitis (AC) is the most common biliary stone disease complication. While there is consensus regarding cholecystectomy for AC, gallbladder drainage is indicated in elderly or high-risk surgical patients.
187. Very-low-dose aspirin and surveillance colonoscopy is cost-effective in secondary prevention of colorectal cancer in individuals with advanced adenomas: network meta-analysis and cost-effectiveness analysis.
作者: Sajesh K Veettil.;Siang Tong Kew.;Kean Ghee Lim.;Pochamana Phisalprapa.;Suresh Kumar.;Yeong Yeh Lee.;Nathorn Chaiyakunapruk.
来源: BMC Gastroenterol. 2021年21卷1期130页
Individuals with advanced colorectal adenomas (ACAs) are at high risk for colorectal cancer (CRC), and it is unclear which chemopreventive agent (CPA) is safe and cost-effective for secondary prevention. We aimed to determine, firstly, the most suitable CPA using network meta-analysis (NMA) and secondly, cost-effectiveness of CPA with or without surveillance colonoscopy (SC).
189. Endoscopic transmural drainage is associated with improved outcomes in disconnected pancreatic duct syndrome: a systematic review and meta-analysis.
作者: Eric Chong.;Chathura Bathiya Ratnayake.;Samantha Saikia.;Manu Nayar.;Kofi Oppong.;Jeremy J French.;John A Windsor.;Sanjay Pandanaboyana.
来源: BMC Gastroenterol. 2021年21卷1期87页
Disconnected pancreatic duct syndrome (DPDS) is a complication of acute necrotizing pancreatitis in the neck and body of the pancreas often manifesting as persistent pancreatic fluid collection (PFC) or external pancreatic fistula (EPF). This systematic review and pairwise meta-analysis aimed to review the definitions, clinical presentation, intervention, and outcomes for DPDS.
190. Lack of Consistent Associations Between Pharmacologic Gastric Acid Suppression and Adverse Outcomes in Patients With Coronavirus Disease 2019: Meta-Analysis of Observational Studies.
作者: Faisal Kamal.;Muhammad Ali Khan.;Sachit Sharma.;Zaid Imam.;Colin W Howden.
来源: Gastroenterology. 2021年160卷7期2588-2590.e7页 191. Risk of Colorectal Cancer and Cancer Related Mortality After Detection of Low-risk or High-risk Adenomas, Compared With No Adenoma, at Index Colonoscopy: A Systematic Review and Meta-analysis.
作者: Abhiram Duvvuri.;Viveksandeep Thoguluva Chandrasekar.;Sachin Srinivasan.;Anvesh Narimiti.;ChandraShekhar Dasari.;Venkat Nutalapati.;Kevin F Kennedy.;Marco Spadaccini.;Giulio Antonelli.;Madhav Desai.;Prashanth Vennalaganti.;Divyanshoo Kohli.;Michal F Kaminski.;Alessandro Repici.;Cesare Hassan.;Prateek Sharma.
来源: Gastroenterology. 2021年160卷6期1986-1996.e3页
The risk of metachronous colorectal cancer (CRC) among patients with no adenomas, low-risk adenomas (LRAs), or high-risk adenomas (HRAs), detected at index colonoscopy, is unclear. We performed a systematic review and meta-analysis to compare incidence rates of metachronous CRC and CRC-related mortality after a baseline colonoscopy for each group.
192. The level and prevalence of depression and anxiety among patients with different subtypes of irritable bowel syndrome: a network meta-analysis.
作者: Zhichao Hu.;Meixuan Li.;Liang Yao.;Yinshu Wang.;Enkang Wang.;Jianye Yuan.;Fengyun Wang.;Kehu Yang.;Zhaoxiang Bian.;Linda L D Zhong.
来源: BMC Gastroenterol. 2021年21卷1期23页
Irritable bowel syndrome (IBS) is a very common functional bowel disorder. However, the difference of depression and anxiety comorbidities among different IBS subtypes is still not well evaluated. This study aims to investigate the difference in the level and prevalence of depression and anxiety among healthy controls and patients with different subtypes of IBS.
193. Alterations in short-chain fatty acids and serotonin in irritable bowel syndrome: a systematic review and meta-analysis.
Short-chain fatty acids (SCFAs) and serotonin (5-hydroxytryptamine, 5-HT) may be associated with the pathogenesis of irritable bowel syndrome (IBS). There are some reports of alterations in SCFAs and 5-HT in IBS, but their results are inconsistent. We aimed to perform a meta-analysis to assess alterations in SCFAs and 5-HT in IBS patients and their potential role in the abnormal brain-gut-microbiota (BGM) axis.
194. Application of artificial intelligence in chronic liver diseases: a systematic review and meta-analysis.
作者: Pakanat Decharatanachart.;Roongruedee Chaiteerakij.;Thodsawit Tiyarattanachai.;Sombat Treeprasertsuk.
来源: BMC Gastroenterol. 2021年21卷1期10页
The gold standard for the diagnosis of liver fibrosis and nonalcoholic fatty liver disease (NAFLD) is liver biopsy. Various noninvasive modalities, e.g., ultrasonography, elastography and clinical predictive scores, have been used as alternatives to liver biopsy, with limited performance. Recently, artificial intelligence (AI) models have been developed and integrated into noninvasive diagnostic tools to improve their performance.
195. Prognostic Factors for Advanced Colorectal Neoplasia in Inflammatory Bowel Disease: Systematic Review and Meta-analysis.
作者: Anouk M Wijnands.;Michiel E de Jong.;Maurice W M D Lutgens.;Frank Hoentjen.;Sjoerd G Elias.;Bas Oldenburg.; .
来源: Gastroenterology. 2021年160卷5期1584-1598页
Patients with inflammatory bowel disease (IBD) have an increased risk of colorectal cancer (CRC). We performed a systematic review and meta-analysis to identify all prognostic factors for advanced colorectal neoplasia (aCRN, high-grade dysplasia, or CRC) in patients with IBD.
196. Radiofrequency ablation versus hepatic resection for recurrent hepatocellular carcinoma: an updated meta-analysis.
作者: Daopeng Yang.;Bowen Zhuang.;Yan Wang.;Xiaoyan Xie.;Xiaohua Xie.
来源: BMC Gastroenterol. 2020年20卷1期402页
The clinical benefits of treatment with radiofrequency ablation (RFA) and repeat hepatic resection (RHR) for recurrent hepatocellular carcinoma (RHCC) remain controversial. This meta-analysis aims to evaluate the outcomes and major complications of RFA versus RHR in patients with early-stage RHCC.
197. The effects of resistant starches on inflammatory bowel disease in preclinical and clinical settings: a systematic review and meta-analysis.
作者: Joshua Montroy.;Rania Berjawi.;Manoj M Lalu.;Eyal Podolsky.;Cayden Peixoto.;Levent Sahin.;Alain Stintzi.;David Mack.;Dean A Fergusson.
来源: BMC Gastroenterol. 2020年20卷1期372页
Inflammatory bowel disease (IBD) is a debilitating chronic disease with limited treatment options. Resistant starches may represent a novel treatment for IBD. However, its efficacy and safety remain unclear. Our objective was to perform a systematic review to summarize the preclinical and clinical effects of resistant starch, which may help guide future studies.
198. Adverse events of video capsule endoscopy over the past two decades: a systematic review and proportion meta-analysis.
作者: Yuan-Chen Wang.;Jun Pan.;Ya-Wei Liu.;Feng-Yuan Sun.;Yang-Yang Qian.;Xi Jiang.;Wen-Bin Zou.;Ji Xia.;Bin Jiang.;Nan Ru.;Jia-Hui Zhu.;En-Qiang Linghu.;Zhao-Shen Li.;Zhuan Liao.
来源: BMC Gastroenterol. 2020年20卷1期364页
A full spectrum of video capsule endoscopy (VCE) adverse events over the past two decades has not been evaluated. We aimed to determine pooled rates, predictors and temporal-trend of VCE adverse events over the past two decades.
199. The clinical efficacy and adverse effects of Entecavir plus Thymosin alpha-1 combination therapy versus Entecavir Monotherapy in HBV-related cirrhosis: a systematic review and meta-analysis.
作者: Dan Peng.;Hai-Yan Xing.;Chen Li.;Xian-Feng Wang.;Min Hou.;Bin Li.;Jian-Hong Chen.
来源: BMC Gastroenterol. 2020年20卷1期348页
Previous studies have demonstrated the benefits of thymosin alpha-1 (Tα1) in anti-virus, immunological enhancement and anti-inflammation. However, it is controversial about the efficacy and safety of entecavir (ETV) plus Tα1 combination therapy versus ETV monotherapy in cirrhotic patients with hepatitis B virus (HBV) infection.
200. Effects of Early Placement of Transjugular Portosystemic Shunts in Patients With High-Risk Acute Variceal Bleeding: a Meta-analysis of Individual Patient Data.
作者: Oana Nicoară-Farcău.;Guohong Han.;Marika Rudler.;Debora Angrisani.;Alberto Monescillo.;Ferran Torres.;Georgina Casanovas.;Jaime Bosch.;Yong Lv.;Dominique Thabut.;Daiming Fan.;Virginia Hernández-Gea.;Juan Carlos García-Pagán.; .
来源: Gastroenterology. 2021年160卷1期193-205.e10页
Compared with drugs plus endoscopy, placement of transjugular portosystemic shunt within 72 hours of admission to the hospital (early or preventive transjugular intrahepatic portosystemic shunt [TIPS], also called preemptive TIPS) increases the proportion of high-risk patients with cirrhosis and acute variceal bleeding who survive for 1 year. However, the benefit of preemptive TIPS is less clear for patients with a Child-Pugh score of B and active bleeding (CP-B+AB). We performed an individual data meta-analysis to assess the efficacy of preemptive TIPS in these patients and identify factors associated with reduced survival of patients receiving preemptive TIPS.
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