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181. Effect of educational lecture on the diagnostic accuracy of Japan NBI Expert Team classification for colorectal lesions.
作者: Yuki Okamoto.;Shiro Oka.;Shinji Tanaka.;Yuki Kamigaichi.;Hirosato Tamari.;Yasutsugu Shimohara.;Tomoyuki Nishimura.;Katsuaki Inagaki.;Hidenori Tanaka.;Kenta Matsumoto.;Ken Yamashita.;Kyoku Sumimoto.;Yuki Ninomiya.;Nana Hayashi.;Yasuhiko Kitadai.;Kenichi Yoshimura.;Kazuaki Chayama.
来源: BMC Gastroenterol. 2021年21卷1期110页
An educational and training program is required for generalization of Japan NBI Expert Team (JNET) classification. However, there is no detailed report on the learning curve of the diagnostic accuracy of endoscopists using JNET classification. We examined the effect of an educational lecture on beginners and less experienced endoscopists for improving their diagnostic accuracy of colorectal lesions by JNET classification.
183. Induction and Long-term Follow-up With ABX464 for Moderate-to-severe Ulcerative Colitis: Results of Phase IIa Trial.
作者: Séverine Vermeire.;Xavier Hébuterne.;Herbert Tilg.;Gert De Hertogh.;Paul Gineste.;Jean-Marc Steens.; .
来源: Gastroenterology. 2021年160卷7期2595-2598.e3页 184. Ten-day bismuth-containing quadruple therapy versus 7-day proton pump inhibitor-clarithromycin containing triple therapy as first-line empirical therapy for the Helicobacter pylori infection in Korea: a randomized open-label trial.
作者: Young-Il Kim.;Jong Yeul Lee.;Chan Gyoo Kim.;Boram Park.;Jin Young Park.;Il Ju Choi.
来源: BMC Gastroenterol. 2021年21卷1期95页
This randomized, open-label trial aimed to compare the efficacy of 10-day bismuth-containing quadruple therapy (BQT) with 7-day proton-pump inhibitor-clarithromycin containing standard triple therapy (STT) as an empirical first-line Helicobacter pylori therapy.
185. A prognostic model for stratification of stage IB/IIA esophageal squamous cell carcinoma: a retrospective study.
作者: Lei-Lei Wu.;Qi-Long Ma.;Wei Huang.;Xuan Liu.;Li-Hong Qiu.;Peng Lin.;Hao Long.;Lan-Jun Zhang.;Guo-Wei Ma.
来源: BMC Gastroenterol. 2021年21卷1期59页
To explore the postoperative prognosis of esophageal squamous cell carcinoma (ESCC) patients with stage IB/IIA, using a prognostic score (PS).
186. Clinical efficacy of fecal microbiota transplantation for patients with small intestinal bacterial overgrowth: a randomized, placebo-controlled clinic study.
作者: Fenghua Xu.;Ning Li.;Chun Wang.;Hanyang Xing.;Dongfeng Chen.;Yanling Wei.
来源: BMC Gastroenterol. 2021年21卷1期54页
Small intestinal bacterial overgrowth (SIBO) is characterized by the condition that bacteria overgrowth in the small intestine. Fecal microbiota transplantation (FMT) has been applied as an effective tool for reestablishing the structure of gut microbiota. However, whether FMT could be applied as a routine SIBO treatment has not been investigated.
187. Community-Based Gastric Cancer Screening Coupled With a National Colorectal Cancer Screening Program: Baseline Results.
作者: Yi-Chia Lee.;Tsung-Hsien Chiang.;Han-Mo Chiu.;Ming-Shiang Wu.;Yen-Po Yeh.;Tony Hsiu-Hsi Chen.; .
来源: Gastroenterology. 2021年160卷6期2159-2161.e4页 188. Lead-Time Trajectory of CA19-9 as an Anchor Marker for Pancreatic Cancer Early Detection.
作者: Johannes F Fahrmann.;C Max Schmidt.;Xiangying Mao.;Ehsan Irajizad.;Maureen Loftus.;Jinming Zhang.;Nikul Patel.;Jody Vykoukal.;Jennifer B Dennison.;James P Long.;Kim-Anh Do.;Jianjun Zhang.;John A Chabot.;Michael D Kluger.;Fay Kastrinos.;Lauren Brais.;Ana Babic.;Kunal Jajoo.;Linda S Lee.;Thomas E Clancy.;Kimmie Ng.;Andrea Bullock.;Jeanine Genkinger.;Michele T Yip-Schneider.;Anirban Maitra.;Brian M Wolpin.;Samir Hanash.
来源: Gastroenterology. 2021年160卷4期1373-1383.e6页
There is substantial interest in liquid biopsy approaches for cancer early detection among subjects at risk, using multi-marker panels. CA19-9 is an established circulating biomarker for pancreatic cancer; however, its relevance for pancreatic cancer early detection or for monitoring subjects at risk has not been established.
189. Participation in Competing Strategies for Colorectal Cancer Screening: A Randomized Health Services Study (PICCOLINO Study).
作者: Nastazja Dagny Pilonis.;Marek Bugajski.;Paulina Wieszczy.;Maciej Rupinski.;Malgorzata Pisera.;Edyta Pawlak.;Jaroslaw Regula.;Michal Filip Kaminski.
来源: Gastroenterology. 2021年160卷4期1097-1105页
Primary colonoscopy and fecal immunochemical testing (FIT) are considered first-tier tests for colorectal cancer (CRC) screening. Although colonoscopy is considered the most efficacious test, FIT might achieve higher participation rates. It is uncertain what the best strategy is for offering population-wide CRC screening.
190. Initial results from a multi-center population-based cluster randomized trial of esophageal and gastric cancer screening in China.
作者: Hongmei Zeng.;Kexin Sun.;Maomao Cao.;Rongshou Zheng.;Xibin Sun.;Shuzheng Liu.;Zhiyi Zhang.;Yuqin Liu.;Guizhou Guo.;Guohui Song.;Yigong Zhu.;Xianghong Wu.;Bingbing Song.;Xianzhen Liao.;Yanfang Chen.;Mingyang Song.;Edward Giovannucci.;Guihua Zhuang.;Wenqiang Wei.;Wanqing Chen.;Jie He.
来源: BMC Gastroenterol. 2020年20卷1期398页
We initiated the first multi-center cluster randomized trial of endoscopic screening for esophageal cancer and gastric cancer in China. The objective of the study was to report the baseline screening findings in this trial.
191. Colorectal Cancer Screening With Repeated Fecal Immunochemical Test Versus Sigmoidoscopy: Baseline Results From a Randomized Trial.
作者: Kristin R Randel.;Anna L Schult.;Edoardo Botteri.;Geir Hoff.;Michael Bretthauer.;Giske Ursin.;Erik Natvig.;Paula Berstad.;Anita Jørgensen.;Per Kristian Sandvei.;Marie Ek Olsen.;Svein Oskar Frigstad.;Ole Darre-Næss.;Espen R Norvard.;Nils Bolstad.;Hartwig Kørner.;Arne Wibe.;Knut-Arne Wensaas.;Thomas de Lange.;Øyvind Holme.
来源: Gastroenterology. 2021年160卷4期1085-1096.e5页
The comparative effectiveness of sigmoidoscopy and fecal immunochemical testing (FIT) for colorectal cancer (CRC) screening is unknown.
192. The Colombian Chemoprevention Trial: 20-Year Follow-Up of a Cohort of Patients With Gastric Precancerous Lesions.
作者: M Blanca Piazuelo.;Luis E Bravo.;Robertino M Mera.;M Constanza Camargo.;Juan C Bravo.;Alberto G Delgado.;M Kay Washington.;Alicia Rosero.;Luz S Garcia.;Jose L Realpe.;Sandra P Cifuentes.;Douglas R Morgan.;Richard M Peek.;Pelayo Correa.;Keith T Wilson.
来源: Gastroenterology. 2021年160卷4期1106-1117.e3页
Helicobacter pylori eradication and endoscopic surveillance of gastric precancerous lesions are strategies to reduce gastric cancer (GC) risk. To our knowledge, this study is the longest prospective cohort of an H pylori eradication trial in a Hispanic population.
193. Colonoscopy With Polypectomy Reduces Long-Term Incidence of Colorectal Cancer in Both Men and Women: Extended Results From the Minnesota Colon Cancer Control Study.
作者: Aasma Shaukat.;Michael Shyne.;Jack S Mandel.;Dale Snover.;Timothy R Church.
来源: Gastroenterology. 2021年160卷4期1397-1399.e3页 194. Tolvaptan therapy of Chinese cirrhotic patients with ascites after insufficient diuretic routine medication responses: a phase III clinical trial.
作者: Jieting Tang.;Yongfeng Wang.;Tao Han.;Qing Mao.;Jun Cheng.;Huiguo Ding.;Jia Shang.;Qin Zhang.;Junqi Niu.;Feng Ji.;Chengwei Chen.;Jidong Jia.;Xiangjun Jiang.;Nonghua Lv.;Yueqiu Gao.;Zhenghua Wang.;Zhong Wei.;Yingxuan Chen.;Minde Zeng.;Yimin Mao.
来源: BMC Gastroenterol. 2020年20卷1期391页
To determine the safety and efficacy of different doses of tolvaptan for treating Chinese cirrhotic patients with or without hyponatraemia who still had ascites after routine therapy with diuretics.
195. Adding ursodeoxycholic acid to the endoscopic treatment and common bile duct stenting for large and multiple biliary stones: Will it improve the outcomes?
作者: Ahmad Hormati.;Mohammad Reza Ghadir.;Seyed Saeed Sarkeshikian.;Faezeh Alemi.;Majid Moghaddam.;Sajjad Ahmadpour.;Abolfazl Mohammadbeigi.;Gholam Reza Sivandzadeh.
来源: BMC Gastroenterol. 2020年20卷1期374页
The role of common bile duct (CBD) stenting in the establishment of bile stream in the elderly patients and the ones who are not good candidates for surgery due to not responding to treatments was well documented in previous studies. The current study aimed at investigating the effect of adding Ursodeoxycholic acid (UDCA) to CBD stenting alone in order to reduce the size of large and multiple CBD stones.
197. A preinstalled nasopharyngeal airway in the right nasal passageway to facilitate nasogastric intubation in anesthetized and intubated patients: a prospective randomized controlled trial.
Nasogastric intubation (NGI) is usually challenging in patients under general anesthesia, with reported success rate at the first attempt to be less than 50%. The aim of this study was to investigate whether a preinstalled nasopharyngeal airway (NPA) in the right nasal passageway can facilitate NGI in anesthetized and intubated patients.
198. Evaluating Responses to Gluten Challenge: A Randomized, Double-Blind, 2-Dose Gluten Challenge Trial.
作者: Maureen M Leonard.;Jocelyn A Silvester.;Daniel Leffler.;Alessio Fasano.;Ciarán P Kelly.;Suzanne K Lewis.;Jeffrey D Goldsmith.;Elliot Greenblatt.;William W Kwok.;William J McAuliffe.;Kevin Galinsky.;Jenifer Siegelman.;I-Ting Chow.;John A Wagner.;Anna Sapone.;Glennda Smithson.
来源: Gastroenterology. 2021年160卷3期720-733.e8页
Gluten challenge is used to diagnose celiac disease (CeD) and for clinical research. Sustained gluten exposure reliably induces histologic changes but is burdensome. We investigated the relative abilities of multiple biomarkers to assess disease activity induced by 2 gluten doses, and aimed to identify biomarkers to supplement or replace histology.
199. Central Reading of Ulcerative Colitis Clinical Trial Videos Using Neural Networks.
作者: Klaus Gottlieb.;James Requa.;William Karnes.;Ranga Chandra Gudivada.;Jie Shen.;Efren Rael.;Vipin Arora.;Tyler Dao.;Andrew Ninh.;James McGill.
来源: Gastroenterology. 2021年160卷3期710-719.e2页
Endoscopic disease activity scoring in ulcerative colitis (UC) is useful in clinical practice but done infrequently. It is required in clinical trials, where it is expensive and slow because human central readers are needed. A machine learning algorithm automating the process could elevate clinical care and facilitate clinical research. Prior work using single-institution databases and endoscopic still images has been promising.
200. A hypocaloric high-protein diet supplemented with β-cryptoxanthin improves non-alcoholic fatty liver disease: a randomized controlled trial.
作者: Fatemeh Haidari.;Abdollah Hojhabrimanesh.;Bizhan Helli.;Seyed-Saeed Seyedian.;Kambiz Ahmadi-Angali.;Behnaz Abiri.
来源: BMC Gastroenterol. 2020年20卷1期349页
Despite promising animal data, there is no randomized controlled trial (RCT) on the effects of high protein (HP)-diet and/or β-cryptoxanthin in non-alcoholic fatty liver disease (NAFLD).
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