当前位置: 首页 >> 检索结果
1. Feasibility and Safety of Pulsed Field Ablation for Coronary Sinus and Left Atrial Appendage Isolation and Mitral Isthmus Ablation: Acute and Chronic Findings.
作者: Vincenzo Mirco La Fazia.;Sanghamitra Mohanty.;Carola Gianni.;Elio Zito.;Nicola Pierucci.;Giuseppe Stifano.;Preem Geeta Torlapati.;Domenico G Della Rocca.;Weeranun Bode.;J David Burkhardt.;Rodney Horton.;Amin Al-Ahmad.;Luigi Di Biase.;Andrea Natale.
来源: Circ Arrhythm Electrophysiol. 2025年e014026页
The safety and efficacy of pulsed field ablation for pulmonary vein and posterior wall isolation in atrial fibrillation ablation are well established; however, evidence regarding its use in extra-pulmonary vein areas remains limited. The aim of this study was to assess the feasibility and durability of pulsed field ablation for coronary sinus (CS) and left atrial appendage (LAA) isolation and mitral isthmus (MI) ablation.
2. Role of Structural Versus Cellular Remodeling in Atrial Arrhythmogenesis: Insights From Personalized Digital Twins.
作者: Andrey V Pikunov.;Roman A Syunyaev.;Rheeda Ali.;Adityo Prakosa.;Anna Gams.;Patrick M Boyle.;Vanessa Steckmeister.;Ingo Kutschka.;Eric Rytkin.;Niels Voigt.;Natalia Trayanova.;Igor R Efimov.
来源: Circ Arrhythm Electrophysiol. 2025年e013898页
Atrial fibrillation (AF) is a progressive disease involving both structural and functional remodeling. Although over the past decade, digital twin-guided therapy has been proposed and applied, accounting for cardiomyocyte functional remodeling remains challenging. We aimed to investigate the contribution of functional remodeling at the cellular level to AF pathogenesis in patients with fibrotic remodeling and to develop novel techniques to predict the location of reentrant drivers.
3. Relationship Between Time-to-First Atrial Tachyarrhythmia Recurrence and Atrial Fibrillation Burden: Implications for Trial Design.
作者: Jason G Andrade.;Martin Aguilar.;Richard G Bennett.;Karim Benali.;Marc W Deyell.;Paul Khairy.;Laurent Macle.
来源: Circ Arrhythm Electrophysiol. 2025年e013971页
Atrial tachyarrhythmia recurrence remains the primary end point of clinical trials evaluating therapeutic pharmacological and nonpharmacological interventions for atrial fibrillation (AF). We sought to examine the relationship between the timing of first atrial tachyarrhythmia recurrence and subsequent AF burden.
5. Ebstein Anomaly and Atrial Conduction: Big Does Not Mean Bad.
作者: Nawin L Ramdat Misier.;Mathijs S van Schie.;Pieter C van de Woestijne.;Hoang H Nguyen.;Annemien E van den Bosch.;Wouter van Leeuwen.;Yannick J H J Taverne.;Natasja M S de Groot.
来源: Circ Arrhythm Electrophysiol. 2025年e014119页 6. Scar Voltage Mapping in Fast Ventricular Tachycardia for Identifying Functional Substrates of Tachycardia Isthmuses: A Proof-of-Concept Study.
作者: Alejandro Carta-Bergaz.;Gonzalo R Ríos-Muñoz.;Verónica Crisóstomo.;Claudia Báez.;Virginia Blanco.;Francisco M Sánchez-Margallo.;Javier Bermejo.;Ángel Arenal-Maiz.
来源: Circ Arrhythm Electrophysiol. 2025年e013793页
Identification of fast ventricular tachycardia (FVT; cycle length <320 ms) isthmuses is often hindered by hemodynamic instability during sustained FVT and by rate-dependent (functional) scar properties. Comparing ultra-high-density voltage heterogeneity maps (0.1-1.5 mV) of the scar area during sinus rhythm (SR) and FVT may delineate the rate-dependent components of the FVT isthmus (FVTI) and improve substrate identification during SR.
7. Cryoballoon Roof Line and Pulmonary Vein Isolation for Persistent Atrial Fibrillation: A Randomized Trial.
作者: Changjin Li.;Yao Zhao.;Ruihan Ju.;Chao Liu.;Shaohua Dong.;Jingwen Song.;Aihong Qin.;Jiang Cao.;Manli Yu.;Xinmiao Huang.;Zhifu Guo.;Songqun Huang.
来源: Circ Arrhythm Electrophysiol. 2025年e013826页 8. Oral Pathobionts Aggravate Myocardial Infarction Through Mobilization of B2 Cells.
作者: Bo-Yan Chen.;Hong Zhu.;Yu-Lin Li.;Jun Zhang.;Shuo Xu.;Lu-Jun Zhou.;Lin-Juan Du.;Ting Liu.;Xue-Nan Sun.;Guo-Cai Tian.;Jie Li.;Xiao-Qian Meng.;Hui-Lin Ye.;Xue-Bing Bai.;Wen-Zhen Lin.;Hu-Xiao Li.;Jian-Xuan Li.;Jian-Yong Sun.;Yan Liu.;Wu-Chang Zhang.;Lu Zhang.;Jing-Yuan Fang.;Daqian Xu.;Mengfei Yu.;Yuxiang Dai.;Qianming Chen.;Sheng-Zhong Duan.
来源: Circulation. 2025年
Myocardial infarction (MI) is a high-prevalence disease that threatens human survival and quality of life worldwide. Considerable evidence has suggested that periodontitis (PD) is detrimental to MI. However, the direct impact of PD on MI is unclear; which oral pathobionts contribute to and how microbial signals regulate the pathogenesis of MI remain obscure.
9. Three-Dimensional Printing of the Human Pericardium to Facilitate Understanding of the Pericardial Reflections, Recesses, and Sinuses.
作者: Yuichiro Miyazaki.;Mark Rimmer.;Warwick J Peacock.;Shili Xu.;Kalyanam Shivkumar.;Shumpei Mori.
来源: Circ Cardiovasc Imaging. 2025年e018410页 10. Dynamic Changes of Distinct Compartmental LV Remodeling Following Septal Myectomy in Hypertrophic Obstructive Cardiomyopathy.
作者: Xinyi Luo.;Guanyu Lu.;Ziyu Liu.;Yinzhu Chen.;Jiehao Ou.;Hongxiang Wu.;Wei Zhu.;Rui Chen.;Huiming Guo.;Hui Liu.;Yuelong Yang.
来源: Circ Cardiovasc Imaging. 2025年e018131页
In hypertrophic obstructive cardiomyopathy, left ventricular mass index (LVMi) regresses following septal myectomy, but the specific dynamics, mechanisms (involving cellular and extracellular compartments), and related factors remain unclear.
11. Estimating the Stroke Risk Threshold for Initiating Non-Vitamin K Antagonist Oral Anticoagulation in Atrial Fibrillation: Markov Decision Model Analysis.
作者: Aleksi K Winstén.;Ville Langén.;K E Juhani Airaksinen.;Konsta Teppo.
来源: Circ Cardiovasc Qual Outcomes. 2025年e012090页
Randomized trials have clearly demonstrated the benefits of anticoagulant therapy in patients with atrial fibrillation who are at high risk of ischemic stroke. However, less is known about the benefit of anticoagulation in low-risk patients, and exactly how low baseline stroke risk justifies further attempts to reduce it with direct oral anticoagulants (DOACs) remains unclear.
12. Clinical Outcomes of Switching From Warfarin to Apixaban or Rivaroxaban in Patients With Atrial Fibrillation: A Nationwide Multidatabase Study.
作者: Dae Hyun Kim.;Darae Ko.;Daniel E Singer.;Alexander Cervone.;Yichi Zhang.;Qiaoxi Chen.;Kueiyu Joshua Lin.
来源: Circ Cardiovasc Qual Outcomes. 2025年e011890页
The benefits of switching from warfarin to direct oral anticoagulants in atrial fibrillation remain unclear.
13. Adjunctive Imaging and Physiology During PCI Among Black and White Medicare Beneficiaries: Disparities in Utilization Patterns and Outcomes.
作者: Frank A Medina.;Ramya C Mosarla.;Joseph M Kim.;Siling Li.;Yang Song.;Robert W Yeh.;Eric A Secemsky.
来源: Circ Cardiovasc Interv. 2025年e015499页
Racial differences in the use and outcomes of intravascular imaging (IVI) and invasive physiology (IP) during percutaneous coronary intervention (PCI) are underreported in the United States.
16. Genetic Variants Associated With Congenital Heart Disease: A Meta-Analysis of Ethnicity and Subtype-Specific Susceptibility.
Congenital heart disease (CHD) is the most common heterogeneous birth defect, with prevalence varying across populations. A comprehensive meta-analysis could refine the genetic risk estimates and enhance our understanding of CHD susceptibility.
17. Investigating the Risk of Arrhythmogenesis Associated With Fentanyl Abuse Using Human and Mouse Cardiomyocytes.
作者: Gema Mondéjar-Parreño.;Shane Rui Zhao.;Xu Cao.;Yu Liu.;Johnson Y Yang.;James W S Jahng.;Jeremy Leitz.;David Wu.;Nazish Sayed.;José Jalife.;Joseph C Wu.
来源: Circulation. 2025年152卷8期563-566页 18. Feasibility, Reproducibility, and Prognostic Value of Exercise Echocardiography for Cardiac Output Reserve Assessment in Fontan Physiology.
作者: Alexander C Egbe.;Omar Abozied.;Ahmed T Abdelhalim.;Sara ElZalabany.;Zeyad Kholeif.;Yogesh N V Reddy.;Barry A Borlaug.
来源: Circ Heart Fail. 2025年e012908页
The purpose of this study was to assess the feasibility and prognostic value of cardiac output (CO) reserve assessment using exercise echocardiography in Fontan patients. We hypothesized that adults with Fontan palliation had lower CO reserve compared with controls, and impaired CO reserve was associated with greater congestion (NT-proBNP [N-terminal pro-B-type natriuretic peptide]) and cardiovascular events (death/transplant/heart failure hospitalization) in Fontan patients.
19. Deep Learning Can Unmask Conduction Tissue Disease From an Ambulatory ECG.
作者: Laurent Fiorina.;Tanner Carbonati.;Baptiste Maille.;Kumar Narayanan.;Pauline Porquet.;Christine Henry.;Jagmeet P Singh.;Eloi Marijon.;Jean-Claude Deharo.
来源: Circ Arrhythm Electrophysiol. 2025年e013695页
Bradyarrhythmia is a common and potentially serious cause of syncope, often difficult to detect due to its intermittent nature. Traditional ECG monitoring methods either provide low diagnostic accuracy or delay diagnosis, increasing the risk of recurrence. We hypothesized that a deep learning-enabled, 24-hour, single-lead ECG could detect past episodes of bradyarrhythmia.
|