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2241. [Characteristics of DNA replication of the chromosomes of the bone marrow cells in patients with acute leukemia].
作者: N N Mamaev.;D Gerchak.;S E Mamaeva.;B V Afanas'ev.;G G Gaponov.
来源: Tsitologiia. 1976年18卷6期718-24页
A study of the late DNA replication pattern in chromosomes of human acute leucaemia cells revealed a significant diffrence from control. Chromosomes, 2,3 and 4-5 of the acute leucaemia cells finish their DNA replication earlier, and chromosomes 1, 13-15 and 16 later, compared to the control chromosomes. The difference in the pattern of DNA replication between analogous chromosomes of acute leucaemia and donor cells was associated with the discovery of large late-replicating chromatin blocks in the pericentromeric regions of leucaemia cell chromosomes. Some relationship is suggested between the pattern of pericentromeric heterochromatin DNA replication and cell differentiation.
2242. [Familial cancer of the larynx].2243. [3 cases of familial laryngeal cancer].2244. [Characteristics of the ploidy, quantity of cytoplasmic RNA and the activity of oxidative-reductive enzymes in melanoblastomas of the vascular tract of the human eye].2245. [Increased frequency of spontaneous chromosome aberrations in lymphocytes in 2 forms of xeroderma pigmentosum].
作者: V M Mikhel'son.;E I Slonimskaia.;V V Prokof'eva.;V D Zhestianikov.
来源: Dokl Akad Nauk SSSR. 1976年230卷4期965-7页 2247. [Relationship between genetic differentiation of the thymus in mice of different strains and malignant growth. IV. Genetic analysis of the thymic index in mice].
作者: P M Borodin.;L Shiuler.;I Iu Videlets.;E V Gruntenko.;D K Beliaev.
来源: Genetika. 1976年12卷7期68-73页
Relative thymus weight was estimated in C3H/He, C57BL/6 mice, their F1 and backcross hybrids, as well as in the progeny of complete diallel crosses between the BALB/c, C3H/He, C57BL/6 and AKR/J strains. On the basis of the analysis of these measurements, a conclusion is drawn that this character is inherited with incomplete dominance of smaller relative weight. The genes determining greater thymus weight are concentrated in the genetic pool of AKR/J and C57BL/6 strains. These genes are characterized by some degree of recessivity with respect to the genes determining smaller thymus weight which are concentrated in the genetic pool of C3H/He and BALB/c strains. The highest concentration of the "plus" and "minus" genes is found in the genetic pools of AKR/J and C3H/He strains respectively.
2248. [Increased sensitivity of tumor cell deoxyribonucleoproteins to acid hydrolysis in the Feulgen reaction].
作者: A V Zelenin.;A A Kushch.;V S Tolmachev.;F A Chebanu.
来源: Dokl Akad Nauk SSSR. 1976年230卷3期709-11页 2249. [Glucose-6-phosphate dehydrogenase and X-chromosome activation].2250. [Malignant tumor of the pancreas in two sisters].2251. [Chromosome disorders in ovarian cancer].2252. [Pigment tumors of vascular tract of human eye].2253. [Advances in the study of the cytogenetics of malignant neoplasms].2254. [Dissemination of ovarian cancer].2255. [Hybrids of normal and malignant cells].2256. [Functional morphology of human chromosomes].2257. [Dynamics of changes in human cells with chromosome and genetic mutations in prolonged cultivation in a stationary phase. Report 1. Study of cells in xeroderma pigmentosum].
作者: S G Vorsanova.;K N Grinberg.;T L Eraĭzer.;Iu A Shapiro.
来源: Arkh Anat Gistol Embriol. 1975年69卷11期74-80页
Ontogenetic changes of normal diploid cells and cells with genetic mutations (LHC-484 from a patient with xeroderma pigmentosum) have been studied under prolonged cultivation in a stationary phase. While investigating the dynamics of complex changes in certain cell properties and cell populations it was found that the cultivated human cells possess a particular pattern of ontogenetic changes for every culture and the dynamics of these changes depends upon the density of the cell population. Two cell subpopulations different in the degree of nucleus heterochromotinization have been discovered.
2259. [3 cases of familial laryngeal cancer].2260. [2 cases of cancer of the upper respiratory tract in brothers]. |