"N Engl J Med"[journal] 检索结果

1941. Routine Spironolactone in Acute Myocardial Infarction.

作者: Sanjit S Jolly.;Marc-André d'Entremont.;Bertram Pitt.;Shun Fu Lee.;Rajibul Mian.;Jessica Tyrwhitt.;Sasko Kedev.;Gilles Montalescot.;Jan H Cornel.;Goran Stanković.;Raul Moreno.;Robert F Storey.;Timothy D Henry.;Shamir R Mehta.;Matthias Bossard.;Petr Kala.;Ravinay Bhindi.;Biljana Zafirovska.;P J Devereaux.;John Eikelboom.;John A Cairns.;Madhu K Natarajan.;J D Schwalm.;Sanjib K Sharma.;Wadea Tarhuni.;David Conen.;Sarah Tawadros.;Shahar Lavi.;Valon Asani.;Dragan Topic.;Warren J Cantor.;Olivier F Bertrand.;Ali Pourdjabbar.;Salim Yusuf.; .; .
来源: N Engl J Med. 2025年392卷7期643-652页

Mineralocorticoid receptor antagonists have been shown to reduce mortality in patients after myocardial infarction with congestive heart failure. Whether routine use of spironolactone is beneficial after myocardial infarction is uncertain.

1942. NEJM at AHA - CRISPR-Cas9 Gene Editing with Nexiguran Ziclumeran for ATTR Cardiomyopathy.

作者: Eric J Rubin.;Jane Leopold.;Stephen Morrissey.
来源: N Engl J Med. 2024年391卷23期e62页

1943. NEJM at AHA - Intensive Blood-Pressure Control in Patients with Type 2 Diabetes.

作者: Eric J Rubin.;Jane Leopold.;Stephen Morrissey.
来源: N Engl J Med. 2025年392卷12期e33页

1944. NEJM at AHA - Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity.

作者: Eric J Rubin.;Jane Leopold.;Stephen Morrissey.
来源: N Engl J Med. 2025年392卷5期e16页

1945. NEJM at AHA - Phase 1 Study of AAV9.LAMP2B Gene Therapy in Danon Disease.

作者: Eric J Rubin.;Jane Leopold.;Stephen Morrissey.
来源: N Engl J Med. 2025年392卷10期e27页

1946. NEJM at AHA - Left Atrial Appendage Closure after Ablation for Atrial Fibrillation.

作者: Eric J Rubin.;Jane Leopold.;Stephen Morrissey.
来源: N Engl J Med. 2025年392卷13期e36页

1947. NEJM at AHA - Catheter Ablation or Antiarrhythmic Drugs for Ventricular Tachycardia.

作者: Eric J Rubin.;Jane Leopold.;Stephen Morrissey.
来源: N Engl J Med. 2025年392卷8期e23页

1948. NEJM at AHA - Routine Spironolactone in Acute Myocardial Infarction.

作者: Eric J Rubin.;Jane Leopold.;Stephen Morrissey.
来源: N Engl J Med. 2025年392卷7期e20页

1949. Inebilizumab for Treatment of IgG4-Related Disease.

作者: John H Stone.;Arezou Khosroshahi.;Wen Zhang.;Emanuel Della Torre.;Kazuichi Okazaki.;Yoshiya Tanaka.;J Matthias Löhr.;Nicolas Schleinitz.;Lingli Dong.;Hisanori Umehara.;Marco Lanzillotta.;Zachary S Wallace.;Mikael Ebbo.;George J Webster.;Fernando Martinez Valle.;Manu K Nayar.;Cory A Perugino.;Vinciane Rebours.;Xinxin Dong.;Yanping Wu.;Qing Li.;Nishi Rampal.;Daniel Cimbora.;Emma L Culver.; .
来源: N Engl J Med. 2025年392卷12期1168-1177页

IgG4-related disease is a multiorgan, relapsing, fibroinflammatory, immune-mediated disorder with no approved therapy. Inebilizumab targets and depletes CD19+ B cells and may be effective for treating patients with IgG4-related disease.

1950. Tirzepatide for Obesity Treatment and Diabetes Prevention.

作者: Ania M Jastreboff.;Carel W le Roux.;Adam Stefanski.;Louis J Aronne.;Bruno Halpern.;Sean Wharton.;John P H Wilding.;Leigh Perreault.;Shuyu Zhang.;Ramakrishna Battula.;Mathijs C Bunck.;Nadia N Ahmad.;Irina Jouravskaya.; .
来源: N Engl J Med. 2025年392卷10期958-971页

Obesity is a chronic disease and causal precursor to myriad other conditions, including type 2 diabetes. In an earlier analysis of the SURMOUNT-1 trial, tirzepatide was shown to provide substantial and sustained reductions in body weight in persons with obesity over a 72-week period. Here, we report the 3-year safety outcomes with tirzepatide and its efficacy in reducing weight and delaying progression to type 2 diabetes in persons with both obesity and prediabetes.

1951. Eugenics, Nazism, and the Journal.

作者: Joan Y Reede.;Eric J Rubin.;David S Jones.;Paul A Lombardo.;Allan M Brandt.;Joelle M Abi-Rached.
来源: N Engl J Med. 2024年391卷19期e50页

1952. Activity of Research-Grade Pemivibart against Recent SARS-CoV-2 JN.1 Sublineages.

作者: Qian Wang.;Yicheng Guo.;Jerren Ho.;David D Ho.
来源: N Engl J Med. 2024年391卷19期1863-1864页

1953. Immunobridging for Pemivibart, a Monoclonal Antibody for Prevention of Covid-19.

作者: Pete Schmidt.;Yong Li.;Myra Popejoy.
来源: N Engl J Med. 2024年391卷19期1860-1862页

1954. Lessons from England's National Health Service.

作者: Timothy G Ferris.;Jennifer Dixon.;David Blumenthal.
来源: N Engl J Med. 2024年391卷19期1852-1859页

1955. Transcatheter Repair or Surgery for Functional Mitral Regurgitation.

作者: Joanna Chikwe.;Michelle M Kittleson.
来源: N Engl J Med. 2024年391卷19期1850-1851页

1956. Toward Curing More Patients with Bladder Cancer - A New Perioperative Strategy.

作者: Matthew I Milowsky.
来源: N Engl J Med. 2024年391卷19期1848-1849页

1957. Case 35-2024: A Newborn with Hypoxemia and a Lung Opacity.

作者: T Bernard Kinane.;Evan J Zucker.;Katherine A Sparger.;Cassandra M Kelleher.;Angela R Shih.
来源: N Engl J Med. 2024年391卷19期1838-1846页

1958. Out of Breath.

作者: Meron Teklu.;Anand Vaidya.;Merve Yonar.;June-Ho Kim.;Edy Y Kim.
来源: N Engl J Med. 2024年391卷19期e43页

1959. Atrophying Pityriasis Versicolor.

作者: Jiawen Chen.;Chao Ji.
来源: N Engl J Med. 2024年391卷19期e42页

1960. Lung Transplantation.

作者: Jason D Christie.;Dirk Van Raemdonck.;Andrew J Fisher.
来源: N Engl J Med. 2024年391卷19期1822-1836页

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