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161. Effect of Social Vulnerability on Efficacy of Bariatric Surgery Versus Medical and Lifestyle Intervention for Type 2 Diabetes: Analysis of the ARMMS-T2D Consortium of Randomized Trials.
作者: Mary Elizabeth Patti.;Bo Hu.;Sarah Kirschling.;Hanna J Wang.;Kathleen Foster.;Yael Sarig.;Donald C Simonson.;Danielle Wolfs.;David Arterburn.;Matthew J O'Brien.;Ashley H Vernon.;John M Jakicic.;Lori Laffel.;Sando Ojukwu.;Sangeeta R Kashyap.;Ali Aminian.;Philip R Schauer.;David E Cummings.;William F Gourash.;Anita Courcoulas.;John P Kirwan.
来源: Ann Intern Med. 2026年179卷3期353-361页
Social determinants of health (SDOH) can affect metabolic health.
165. Predicting Long-Term Risk for Prostate Cancer Mortality Following a Prostate-Specific Antigen Screening Test: Prognostic Model Development and External Validation.
作者: Patrick Lewicki.;Ralph Jiang.;Archana Radhakrishnan.;Alex Bryant.;Matthew Schipper.;Todd M Morgan.;Kristian Stensland.
来源: Ann Intern Med. 2026年179卷3期321-329页
Despite the scale of prostate-specific antigen (PSA) testing for prostate cancer (PCa) screening, prediction models do not predict time-to-event end points or adjust for patient life expectancy.
166. The Prevalence and Characteristics of Difficult Patient Encounters : A Systematic Review and Meta-analysis.
作者: Jeffrey L Jackson.;Akira Kuriyama.;Jeff Whittle.;Anthony Davis-Maxwell.;Michelle Thompson.;Mary G Murphy.;Suma Gondi.;Kristen Brennan.;Cory Ganshert.;Kathlyn E Fletcher.
来源: Ann Intern Med. 2026年179卷3期382-393页
Patients are sometimes experienced as difficult by their providers.
168. Iron Deficiency Anemia.
Iron deficiency anemia (IDA) is caused by iron deficiency, a common yet underrecognized clinical entity. Populations at greatest risk include children, menstruating and pregnant persons, and people of low socioeconomic status. Timely diagnosis and management of iron deficiency are key to preventing IDA and require thorough assessment of the underlying cause and appropriate iron repletion through either oral or parenteral therapy. Blood transfusion does not provide adequate elemental iron but is sometimes indicated along with iron therapy in patients with cardiovascular compromise, active bleeding, or severe anemia where more rapid correction is warranted. Alternative causes of anemia can be differentiated by red blood cell morphology and reticulocyte count and should be considered if anemia persists despite adequate repletion of iron stores.
170. In HFrEF, adding digitoxin to standard care reduced a composite of death or first worsening HF hospitalization at a median 36 mo.
GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text].
171. GLP-1RAs increase risk for cholelithiasis and GERD but not other GI or biliary adverse events vs. placebo.
GIM/FP/GP: [Formula: see text] Endocrinology: [Formula: see text] Gastroenterology: [Formula: see text].
172. Effectiveness of Sodium-Glucose Cotransporter-2 Inhibitors Versus Glucagon-like Peptide-1 Receptor Agonists on Diabetic Foot Disease : An Emulated Target Trial.
作者: Frederik P B Kristensen.;Diana H Christensen.;Brian C Callaghan.;Jens S Nielsen.;Henning Andersen.;Henrik T Sørensen.;Reimar W Thomsen.
来源: Ann Intern Med. 2026年179卷3期340-352页
The effects of sodium-glucose cotransporter-2 inhibitors (SGLT-2is) on diabetic foot disease have been mixed in prior trials of SGLT-2is compared with placebo. The comparative risk for diabetic foot disease with SGLT-2is compared with glucagon-like peptide-1 receptor agonists (GLP-1RAs) is unknown.
173. In adults at high risk for ventricular arrhythmia, treatment to increase potassium to high-normal levels improved a composite outcome.
GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text].
175. In adults hospitalized with acute HF, predischarge influenza vaccination reduced a composite of mortality or readmission at 1 y.
GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text] Infectious Disease: [Formula: see text].
176. In older adults, high- vs. standard-dose influenza vaccine reduced hospitalization for influenza or pneumonia.
GIM/FP/GP: [Formula: see text] Public Health: [Formula: see text].
177. In symptomatic AF, nurse-led pre-ablation lifestyle treatment reduced repeat ablations or cardioversions at 1 y.
GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text].
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