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241. Time-Restricted Feeding Reduces Body Mass Index, Visceral Adiposity, Systemic Inflammation, and Clinical Disease Activity in Adults With Crohn's Disease: A Randomized Controlled Study.
作者: Natasha Haskey.;Jiayu Ye.;Ayva Lewis.;Munazza Yousuf.;Raylene A Reimer.;Maitreyi Raman.
来源: Gastroenterology. 2026年 242. Genomic Insights Into Inflammatory Bowel Disease in United States Hispanic Participants: An Ancestry-Focused Study.
作者: Ashley H Beecham.;Dermot P B McGovern.;Steven W Brugger.;Mary F Davis.;Esther A Torres.;Lissette Gomez.;Dalin Li.;Paola Lopez-Marte.;Mark J Daly.;Christine Stevens.;Shaohong Yang.;Sweta Sinha.;Emebet Mengesha.;James Leavitt.;Oriana M Damas.;Maria A Quintero.;Stephan R Targan.;Shervin Rabizadeh.;Ksenija Sabic.; .;Judy H Cho.;Maria T Abreu.;Jacob L McCauley.;Talin Haritunians.
来源: Gastroenterology. 2026年
Genetic admixture of United States Hispanic individuals provides a unique opportunity to examine ancestral origins of inflammatory bowel disease (IBD) risk. In ∼7.3K Hispanic participants (1660 IBD cases; 5614 controls), we examined ancestral heterogeneity of IBD clinical phenotypes and sought to identify IBD risk loci that displayed heterogeneity of effect or were ancestry-specific.
243. Gut microbiota dysbiosis and hepatic inflammation in morphine dependence and withdrawal: insights from a rat model.
作者: Shirin Yousefi.;Mahsa Sadeghi-Adl.;Samira Tarashi.;Seyed Davar Siadat.
来源: BMC Gastroenterol. 2026年26卷1期
Opioid dependence, particularly morphine, has been linked to gut microbiota dysbiosis and systemic inflammation, yet the interplay between gut microbial alterations and hepatic inflammatory responses remains poorly understood.
246. Predictive factors of metabolic dysfunction associated steatotic liver disease (MASLD) among individuals with cardio-metabolic risk factors, multicenter cross-sectional study, North East Ethiopia.
作者: Getachew Bizuneh Aydagnuhm.;Aklile Semu Tefera.;Gebru Tesfaw Getahun.;Ermiyas Endewunet Melaku.
来源: BMC Gastroenterol. 2026年26卷1期
Metabolic dysfunction–associated steatotic liver disease (MASLD), formerly known as NAFLD, is a growing global public health concern, affecting 30–40% of the population. Its epidemiology in sub-Saharan Africa, including Ethiopia, is still under-investigated. This study aimed to assess the prevalence of MASLD and its associated factors among individuals with cardio metabolic risk factors.
247. Hospitalization rate for ulcerative colitis and Crohn's disease in Brazil and its correlation with socioeconomic inequalities.
作者: Jenny Diniz Malentaqui Lousada.;Carla Peluso.;Bianca Bianco.;Jean Henri Maselli-Schoueri.;Luiz Vinicius de Alcantara Sousa.;Fernando Rocha Oliveira.;Laércio da Silva Paiva.
来源: BMC Gastroenterol. 2026年26卷1期
Inflammatory bowel diseases (IBD), mainly represented by Crohn’s disease and ulcerative colitis, have a multifactorial etiology and a growing incidence in developing countries. In Brazil, studies on their occurrence and relationship with social conditions remain scarce, which reinforces the importance of updated epidemiological analyses.
248. Energy metabolism alteration and gene expression reprogramming in a cell model of high fat load non-alcoholic fatty liver disease.
作者: Tianran Zhou.;Yuhang Zhou.;Cagla Cömert.;Xiao-Yu Zhou.;Lin Lin.;Lars Bolund.;Johan Palmfeldt.;Yonglun Luo.;Peter Bross.;Guangdong Tong.
来源: BMC Gastroenterol. 2026年26卷1期
Metabolic rewiring plays a crucial role in the energy metabolism of hepatocytes during steatosis. However, the precise alterations in energy metabolism remain unclear. The aim of this study was to investigate the effects of lipid exposure on cellular energy metabolism and gene expression in a cellular model of non-alcoholic fatty liver disease (NAFLD).
254. Comparative analysis of bowel preparation quality for colonoscopy: a survey of outpatients and inpatients.
作者: Lin Jiang.;Man Wu.;Can Dong.;Yu Lei.;Junlin Li.;Tianxu Chen.;Ping Zhao.;Qian Deng.;Juan Rong.;Zhiyao Chen.;Xiaobin Sun.
来源: BMC Gastroenterol. 2026年26卷1期
The quality of bowel preparation significantly affects the outcome of colonoscopy. Adequate bowel cleansing improves diagnostic accuracy while reducing the need for repeat procedures. Currently, evidence regarding factors associated with inadequate bowel preparation in outpatients and inpatients remains limited. Therefore, this study aimed to compare the quality of bowel preparation between outpatients and inpatients undergoing colonoscopy and to identify risk factors for inadequate bowel preparation.
255. Characteristics and outcomes of patients undergoing colonoscopy in Gaza Strip hospitals: a retrospective study.
作者: Khaled Siyam.;Khamis Elessi.;Mosheer Al-Dahdouh.;Ahmed Eid.;Hasan Hamdan.;Mustafa Abu Jayyab.;Issam Awadallah.;Tayseer Afifi.
来源: BMC Gastroenterol. 2026年26卷1期
Colonoscopy is a key diagnostic and therapeutic tool for colorectal diseases, including cancer, polyps, and bleeding disorders. In low-resource settings such as the Gaza Strip, challenges in access to healthcare may influence patient characteristics, indications, and outcomes of colonoscopy. Understanding these patterns is critical to improving diagnostic services and patient care.
256. Effects of age and drug use on lower gastrointestinal bleeding: a retrospective single-center experience.
作者: Soner Onem.;İbrahim Ethem Güven.;Murat Derebey.;Mehmet Emin Arayici.;Süleyman Dolu.
来源: BMC Gastroenterol. 2026年26卷1期
Lower gastrointestinal bleeding is a prevalent issue in the general population, particularly among older adults. Identifying risk factors is essential for improving healthcare outcomes. This study seeks to evaluate the clinical outcomes related to the use of medications recognized as risk factors, as well as the influence of age, in patients experiencing lower gastrointestinal hemorrhage. The primary endpoint of the study is to examine the effect of age and medication use on 30-day mortality, while the secondary endpoint was to investigate the need for endoscopic treatment, amount of transfusion, need for surgery-embolization, and length of hospital stay.
257. Interventional Endoscopic Ultrasound.
作者: David L Diehl.;Kenneth F Binmoeller.;Nazia Hasan.;Mouen Khashab.;Rami El Abiad.;David E Loren.
来源: Gastroenterology. 2026年
Endoscopic ultrasound (EUS) has evolved from a diagnostic method for staging tumors and diagnostic tissue acquisition to a technology that has revolutionized minimally invasive endoscopic care across the disease spectrum. Recent years have witnessed a rapid advance in the number and types of procedures that are performed and in the devices that are designed to deliver EUS-guided interventions. These advances offer safer, less-invasive alternatives to traditional therapies and define disruptive technologies that are impacting patient care. The purpose of this review is to discuss the state of the art in therapeutic EUS procedures, focusing on current advances that are transforming endoscopic patient care.
258. Correction: Evaluation of PINK1 protein expression as a predictive marker for the efficacy of adjuvant chemotherapy in colorectal cancer: a retrospective study.
作者: Takatsugu Fujii.;Masataka Hirasaki.;Yasuo Kamakura.;Tomonori Kawasaki.;Satoshi Yamasaki.;Yasuhiro Ishiyama.;Chikashi Hiranuma.;Tetsuya Hamaguchi.;Yasumitsu Hirano.;Shinichi Sakuramoto.
来源: BMC Gastroenterol. 2026年26卷1期99页 |