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7081. [Analysis of lymphocytic clone formation after stem cell transplantation and immunological reconstitution by gene fingerprinting].
To analyze T lymphocytic clone formation in patients with malignant disease after bone marrow or peripheral blood stem cell transplantation and to understand the relationship between immunological reconstitution and clinic remission.
7082. [Hematopoietic stem cell transplantation for beta-thalassemia major].
To discuss the feasibility of hematopoietic stem cell transplantation for beta-thalassemia major.
7083. [The expression of glial cell derived neurotrophic factor and its receptor GDNFR-alpha and GDNFR-beta mRNA in spinal cord, brainstem and frontal cortex during morphine withdrawal in rats].
To investigate the expression of glial cell derived neurotrophic factor (GDNF) and its receptor GDNFR-alpha (GFRalpha-1) and GDNFR-beta (Ret) genes and the effects of muscarinic receptor antagonists, NMDA receptor antagonist, inhibitor of nitric oxide synthase on the expression of these genes in the spinal cord, brainstem and frontal cortex during morphine withdrawal, and to observe the effects of GDNF antisense oligoneucleotide (i.c.v) on the morphine withdrawal symptoms in rats.
7084. [A pilot study in treatment of systemic lupus erythematosus by autologous bone marrow transplant].
To explore the clinical effect for treatment of SLE by autologous bone marrow transplantation(ABMT).
7085. [A study on the relations of soluble interleukin-2 receptor and CD+25 cell with acute graft-versus-host disease].
Acute graft-versus-host disease (aGVHD) is one of the major complications after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Prediction of human aGVHD may be of help in its diagnosis and therapy.
7086. [Allogeneic peripheral blood stem cell transplantation for treatment of leukemia].
To observe engraftment kinetics, incidence and severity of graft-versus-host disease (GVHD) and clinical outcome in 40 recipients undergoing allogeneic peripheral blood stem cell transplantation (allo-PBSCT).
7087. [The presentation of neo gene in chimeric mice obtained from ES cells].
To explore the potentiality of the mouse ES cell line which is employed in our laboratory were transfected with neo gene and selected with G418. Some ES cell clones expressing neo gene were obtained. After ES clones were picked up and expanded, the ES cells were mircoinjected into blastocysts and implanted miceuterus. 60 blastocysts were implanted into 5 mice. Finally, 3 chimeric mice with neo gene were born. PCR was carried out to analyze the presentation of neo gene in tissues of chimeric mice. The results showed that many tissues harbored the neo gene, including skin, liver and blood et al.
7088. [Exploration on protective effect of Chinese herbal medicines on hematopoietic and immune systems against radio-injury and its mechanism].7089. [Effect of ginsenosides on proliferation and differentiation of human CD34+ hematopoietic stem/progenitor cells].
To investigate the effect of ginsenosides (GS) on proliferation and differentiation of human CD34+ stem/progenitor cells.
7090. [Application of sequential culture in assisted reproductive technique].
To investigate the effects of sequential culture technique on the outcomes of in vitro fertilization-embryo transfer(IVF-ET).
7091. [Effect of composite blood-activating decoction on expression of adherent molecule and cyclin in bone marrow hematopoietic cells in mice of immune-induced aplastic anemia].
To study the effect of composite blood-activating decoction (CBAD) on expression of adherent molecule CD49 d and cyclin D2 in bone marrow hematopoietic cells in experimental immune-mediated aplastic anemia (AA) mice.
7092. [Experimental study on effect of yishen shengxue tablet in treating aplastic anemia].
To study the mechanism of Yishen Shengxue Tablet (YSSXT) in treating aplastic anemia.
7093. [Potentiated effects of total saponins of Panax Ginseng on inhibition of leukemic cells by cytotoxic drugs].
To investigate the potentiated effects of total saponins of Panax Ginseng (TSPG) on inhibition of leukemic progenitor cells by cytotoxic drugs in acute myelocytic leukemia.
7094. [Review on experimental studies of Chinese drugs in antagonizing bone marrow inhibition caused by chemicals].7095. [Influence of flavonoid of Astragalus membranaceus's stem and leaves on the function of cell mediated immunity in mice].
To investigate the immune regulation of flavonoid of Astragalus membranaceus's stem and leaves (FAM).
7096. [Clinical and experimental study on the treatment of myelodysplastic syndromes with fuzheng quxie tablet].
To study the mechanism of Fuzheng Quxie Tablet (FZQXT) in treating myelodysplastic syndromes (MDS).
7097. [The effect of rhIL-11 on hematopoiesis of rhesus monkeys irradiated with 60Co gamma-rays].
To study the therapeutic effect of recombinant human interleukin-11 (rhIL-11) on acute radiation sickness in monkeys.
7098. [Mobilization of autologous peripheral blood stem cells by combined chemotherapy and rhG-CSF].
To study the effect of cyclophosphamide (CTX) combination chemotherapy and recombinant human granulocyte colony-stimulating factor (rhG-CSF) on autologous peripheral blood stem cells (APBSC) mobilization.
7099. [Effects of PML and PML-RAR alpha antisense oligonucleotides on promyelocytic leukemia cell line NB4].
To investigate the different effects of anti-PML (promyelocytic leukemia) and anti-PML/RAR alpha (promyelocytic leukemia/retionic acid receptor alpha) antisense oligonucleotides on cell growth, expression of PML-RAR alpha mRNA and PML-RAR alpha/PML protein location of NB4 cell line.
7100. [Mechanism of retinoic acid receptor alpha-mediated growth inhibition of gastric cancer cells by all-trans retinoic acid].
To study the mechanism of retinoic acid receptor alpha(RAR alpha) in mediating growth inhibition of gastric cancer cells by all-trans retinoic acid(ATRA).
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