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7041. [In vitro cotransfer human multidrug resistance gene (mdr-1) and dihydrofolate reductase gene (DHFR) into human CD(34)(+) progenitor cells to broaden the spectrum of drug resistance].
To explore the feasibility of cotransferring human mdr-1 gene and DHFR gene into human CD(34)(+) progenitor cells to broaden the spectrum of drug resistance and improve the tolerance of myelosuppression following combination chemotherapy.
7042. [The difference of intracellular cytokines produced by different lymphocyte subsets of cord blood and adult peripheral blood].
To explore the difference of intracellular cytokines between cord blood and adult peripheral blood and elucidate its significance for GVHD.
7043. [Expression of adhesion molecules on CD34(+) hematopoietic precursor cells from normal human bone marrow, cord blood and mobilized blood].
作者: Y Xiong.;A Teng.;J Kong.;J Wang.;K Yang.;T Shen.
来源: Zhonghua Xue Ye Xue Za Zhi. 2001年22卷6期285-7页
To investigate the expression of adhesion molecules on CD(34)(+) hematopoietic precursor cells from normal human bone marrow, cord blood and mobilized peripheral blood, and the mechanism of peripheral blood precursor cells mobilization.
7044. [The study of low dose radiation inducing hormesis effect on hematopoietic system].
To study the hormesis effect on hematopoietic system induced by low dose radiation.
7045. [A novel rat aplastic anemia model induced by 5-fluorouracil combined with busulfan].
To develop an aplastic anemia model with hematopoietic stem cell failure in rats.
7046. [Improvement of combination chemotherapy tolerance of human umbilical cord blood CD(34)(+) cells transducted with double drug resistance genes by a bicistronic retroviral vector].
To explore whether human umbilical cord blood hematopoietic progenitor cells transduced with human aldehyde dehydrogenase class 3 (ALDH3) and multidrug resistance gene (MDR1) could increase resistance to 4-hydroxycyclophosphamide (4-HC) and P-glycoprotein effluxed drugs.
7047. [Umbilical cord blood transplantation (UCBT) in thalassemia children].
作者: S Huang.;J Fang.;C Chen.;R Bao.;Y Wu.;D Zhou.;S Li.
来源: Zhonghua Xue Ye Xue Za Zhi. 2001年22卷4期182-5页
To evaluate the efficacy of allo-UCBT in thalassemia children.
7048. [Human cytomegalovirus inhibits the proliferation of CFU-MK in vitro].
作者: S Pan.;Z He.;F Chen.;Q Wang.;X Zou.;L Huang.;M Yang.
来源: Zhonghua Xue Ye Xue Za Zhi. 2001年22卷3期135-7页
To investigate the effect of human cytomegalovirus (HCMV) on the proliferation of colony forming unit-megakaryocyte (CFU-MK).
7049. [Exploration of high expressions of retroviral vectors containing hFIX minigene in murine myoblast cells].
To explore the effect of different vector structure on hF IX protein expression in murine myoblasts in order to construct more efficient expression vector for my oblast-mediated gene therapy for hemophilia B.
7050. [Study of telomerase activity and its related genes expression in leukemia cells].
To investigate the changes of telomerase activity and its related genes expression in leukemia cells and their roles in leukemogenesis.
7051. [Dynamic monitoring of Ph positive cells during early post-transplant period in chronic granulocytic leukemia by interphase FISH].
作者: S Liu.;Q Li.;M Han.;W Pan.;L Bo.;S Qin.;X Liu.;X Li.;L Qian.
来源: Zhonghua Xue Ye Xue Za Zhi. 2001年22卷2期68-71页
To assess the effectiveness of transplantation and observe the kinetics of residual leukemic cells during early post-transplantation period in chronic granulocytic leukemia (CGL).
7052. [GATA-2 gene expression in leukemia patients and its significance].
作者: L Wang.;L Dong.;G Liu.;Y Lin.;J Zhang.;S Jia.;S Lu.;H Pian.;B Yao.;H Chen.
来源: Zhonghua Xue Ye Xue Za Zhi. 2001年22卷1期27-9页
To investigate GATA-2 gene expression in leukemia patients and its clinical significance.
7053. [Correlation of cell apoptosis induction with expression of human beta5 integrin on hematopoietic cells].
作者: L Yin.;X Zhao.;S Fu.;F Garacia-Sanchez.;A B Deisseroth.
来源: Zhonghua Xue Ye Xue Za Zhi. 2001年22卷1期13-6页
To investigate the function of alpha(v)beta5 integrin in hematopoietic cells.
7054. [Experimental studies on the characteristics of suicide gene system HSV-tk/GCV and its effect on dendritic cells].
To study the characteristics of suicide gene system of the herpes simplex virus thymidine kinase (HSV-tk) gene in tumor cells and explore the apoptosis phenomena in this system and its effect on dendritic cells (DC).
7055. [Long-term expression of MHC-I gene in recipient mice].
To explore the possibility of long-term expression of transferred MHC-I gene in recipient mice.
7056. [Umbilical cord blood stem cells transplantation from an unrelated donor into an adult with severe aplastic anemia].
作者: P Mao.;C Liao.;Z Zhu.;H Wang.;S Wang.;W Mo.;Y Ying.;Q Li.;B Liu.
来源: Zhonghua Xue Ye Xue Za Zhi. 2000年21卷10期533-6页
To evaluate the availability of the treatment of adult severe aplastic anemia with unrelated allo-cord blood stem cell transplantation (CBSCT).
7057. [Experimental study on ex vivo expansion of CD(34)(+) umbilical cord blood cells].
To investigate the potential possibility that to expanse ex vivo umbilical cord blood (UCB) cells to an amount sufficient adults transplantation.
7058. [The impact of hepatitis B virus infected patients or donors on the outcome of hematopoietic stem cell transplantation].
作者: S Feng.;M Han.;L Zhang.;C Li.;L Qiu.;H Li.;Z Wang.;R Jiang.;W Yan.;Z Han.
来源: Zhonghua Xue Ye Xue Za Zhi. 2000年21卷8期414-6页
To investigate the impact of recipients and/or donors infected with hepatitis B on the outcome of hematopoietic stem cells transplantation (HSCT).
7059. [Effects of different cryoprotectants on biological properties of hematopoietic cells derived from cord blood].
To search for effective cryoprotectants that can be used in cord blood bank to cryopreserve hematopoietic cells.
7060. [Analysis of surface markers of expanded human umbilical cord blood cells in vitro].
To explore the optimal timing for in vitro expansion and transplantation of umbilical cord blood hematopoietic cells.
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