To determine the effect of butylphthalide on the expressions of p38 mitogen-activated protein kinase and extra-cellular signal regulated kinases (ERKs) in the brain tissue of rats with Alzheimer's disease (AD).

To investigate the effect of modified Yupingfeng granule on nuclear factor-kappaB (NF-kappaB)expression in mice with allergic contact dermatitis (ACD).

To investigate the effects of epigallocatechin-3-gallate (EGCG) on the proliferation of SW620 cells and the expression of PAK1 gene.

To investigate the relationship between aquaporin 4 (AQP4) in alveolar type II (AT-II) cells and MAPK signaling pathway in rats with early-stage oleic acid-induced acute lung injury (ALI) and acute respiratory distress syndrome (ARDS).

The explants cells of Nicotiana Tobacum undergo the process of dedifferentiation and redifferentiation under the treatment of phytohormone with different contentrations. By monitoring the change of plastids and the expression of FtsZ protein, which functions in the progress of chloroplast division, we show that chloroplasts turn into amyloid and hypostasis when explants dedifferent and at the same time the expression of FtsZ proteins decreases. When explants redifferent and bud, hypostasis turn back into the chloroplast and the expression of FtsZ protein restores. The concurrence of fluctuant expression of FtsZ protein and the progress of bud differentiation and formation of chloroplast play essential roles in the growth of green plant.

(-)-Epigallocatechin-3-gallate (EGCG), a main constituent of green tea polyphenols, plays important roles in antioxidative, anti-senescence, anti-tumor, anti-inflammation and bacterail action. In this study, effects of EGCG on the expression of IL-1beta gene and the IL-1beta level at wound sites during cutaneous wound healing were investigated with histological stain, ELISA and RT-PCR technique. The results show that EGCG (50 mg/L) inhibited the expression of IL-1beta gene and reduced the IL-beta level at wound sites at 72 h after cutaneous wound, but not change the expression of IL-1beta gene and the IL-1beta level at early stage (< or =24 h).

To investigate the mechanism related to the inhibition of leukemia K562 cells by berbamine.

To study the effects of Polygona-polysaccharose (PSP) on blood glucose level and the mechanism of protection on diabetic rats induced by streptozotocin (STZ).

To research the effect of Jianpi Jiedu decoction (JPJDT) to PTEN/ERK1 of athymic mice with hepatocellular carcinoma.

To investigate the expression of tissue transglutaminase( tTG) in unilateral ureteral obstruction (UUO) rats and the intervention of Folium Ginkgo (GBE).

To inquire into the cerebral gene change of effect of Jingui Shenqiwan and Youguiwan for animal model of kidney-yang asthenia caused by excessive physical and sexual activities, which may study the effect mechanism of the medicine with syndrome disproved therapeutic efficacy of drugs used.

To investigate the mechanism of quercetin on the inhibition of the lymphatic metastasis in human gastric cancer cells MGC-803.

To investigate the protective effects of ginkgolide B and hypoxic preconditioning against acute hypoxia injury in mice.

To investigate the suppressive effect of resveratrol on growth of U251 human glioma cells and its correlated mechanism.

Use proteomic technique to research the effects of Qishenyiqi formula in acute myocardial infarcted rats, and further explore its protein-level mechanism.

Selecting an effective way to increase salt-resistance of Prunella vulgaris seed through seed priming technology.

During the infection of host cells, IE2 protein is one of the first and most abundantly expressed products of HCMV genome, which plays an important role in the controlling of cell cycle and apoptosis. But the correlation between expression level and anti-apoptotic activity of IE2 protein is still not clear. In this study, we successfully established a HCMV IE2 protein expression cell line that was controlled by Tet-On system. The effect of IE2 protein on cell apoptosis and the expression of p53 was detected under different condition of induction. Our results showed that the IE2 protein could inhibit cell apoptosis induced by TNF-alpha. Additionally, the anti-apoptotic activity of IE2 protein seemed to be relevant to its expression level. However, we failed to detect any difference of p53 expression between the IE2 protein expression and non-expression cells. These data indicated that the IE2 protein might inhibit cell apoptosis through regulating different signal pathways.

To investigate the inhibitory effect of ampelopsin (AMP) combined with adriamycin (ADR) on growth of human leukemia multidrug resistant cell line K562/ADR.

To observe the effect of heart protection on diabetic cardiomyopathy in rats by tripterysium glucosides.

To explore the effect and the mechanism of panax notoginseng saponins (PNS) on the vascular intima hyperplasia and expression of proliferating cell nuclear antigen (PCNA) after aortic intima injury induced ballcon in rats.