to explore the effects of IL-10 on the expression of interferon regulatory factor-1 (IRF-1) after anoxia-reoxygenation in vitro.

to observe the effect of PolyI:C on the expression of TLR3 and inflammation cytokine in the airway smooth muscle cells ASMCs of rat, to investigate relationship between the expression of Toll-like receptor 3 (TLR3) in the airway smooth muscle cells and airway inflammation.

To investigate the effect of dracorhodin perchlorate (DP) on inhibiting high glucose-induced serum and glucocorticoid induced protein kinase 1 (SGK1) and fibronectin (FN) expression in human mesangial cells (HMC), and its mechanism of prevention and treatment on renal fibrosis in diabetic nephropathy (DN) .

By applying 40-400 mmol x L(-1) NaCl, 20-200 mmol x L(-1) NaHCO3, and 5%-30% PEG, this paper studied the effects of saline-alkali and drought stress on the seed germination and Na+/H+ antiporter gene (TvNHX1) expression of Tripolium vulgare. 40-160 mmol x L(-1) NaCl, 20 mmol x L(-1) NaHCO3, and 5%-10% PEG-6000 had less effects on the seed germination; while > or = 240 mmol x L(-1) NaCl decreased the seed germination rate, root length, and shoot length (P < 0.05), > or = 50 mmol x L(-1) NaHCO3 decreased the seed germination rate (P < 0.05), 130 mmol x L(-1) NaHCO3 decreased the seed germination potential, root length, and shoot length (P < 0.05), and > or = 15% PEG delayed the seed germination. TvNHX1 transcripts were basically constitutive at germination stage, but their expression increased distinctly at 160 mmol x L(-1) NaCl, 100 mmol x L(-1) NaHCO3, and 10% PEG. Under salt and drought stress, the expression of TvNHX1 changed in-phase with the phenotype change of germinated seeds, suggesting that TvNHX1 play important roles in the tolerance of T. vulgare against adversity stress.

To investigate the effects of matrine on proliferation, cell cycle, apoptosis rate and beta-catenin-dependent transcriptional activity in cultured hepatoma cell line Hep3B.

To investigate the mechanism of tea polyphenol in inhibiting microsatellite instability (MSI) of colorectal cancer.

To investigate the effect of HCV DF (Double-shift F) protein on the expression p16 and p21 in HepG(2); cells.

To investigate the effect of microRNA-mediated exogenous Id3 gene silencing on proliferation and apoptosis of human lung adenocarcinoma A549 cells in vitro.

To explore the expression changes of age-related genes in different stages of aging and the regulating effects of Chuanxiong extract on it.

To explore the effect and potential mechanism of apoptosis in the Eca-9706 cells induced by soyasaponin Bb.

With the development of cell culture technology in vitro, people have successfully cultivated osteoblast cells of typical characteristics from a number of animal skull, bone marrow, periosteum and bone tissues; studies have shown that these osteoblasts have good biological characteristics, can create bone tissue in different environments, can apply joint stand for the construction of tissue engineered bone, be implanted in the body to repair bone defects. In this article, the source of osteoblast, regulatory factor, composite graft and Chinese medicine research progress were reviewed.

To explore the effects of rosiglitazone (RSG), an agonist of peroxisome proliferators-activated receptor-gamma (PPAR-gamma), on the up-regulation of connective tissue growth factor (CTGF) and the deposition of type I and type III collagens in the pulmonary arteries of rats suffering from fibrosis in lung.

It was proven that Vitamin C could inhibit the growth of many types of tumors as an antioxidant. The aim of this study is to explore role of Vitamin C in proliferation and apoptosis of lung carcinoma cell line A549 and the underlying mechanism.

It has been demonstrated that bone morphogenetic protein 7 (BMP7) may both inhibit and enhance cell proliferation of many kinds of cancers, but the impact of BMP7 on lung cancer cells and the exact mechanisms are not clear. The aim of this study is to investigate the effect of BMP7 on proliferation of lung carcinoma cells and explore the roles of different types of I receptors in BMP7 signal transmission by blocking endogenous BMPRIs.

To investigate the effect of all-trans retinoic acid on the proliferation of and Fas protein expression in malignant melanoma A375 cells in vitro.

To study the expression pattern of SDF-1 in the NRK49F cells and the role of TGF-beta1 in mediating the expression of SDF-1.

To construct modified promoter of human endothelial nitric-oxide synthase(eNOS) and investigate transcriptional activity of the eNOS promoter via a hypoxia model of human umbilical vein endothelial cells-12(HUVEC-12) stimulated by Cobaltous chloride in vitro.

To explore the effect of Ligusticam chuanxiong extract (CXE) on lifespan of Caenorhabditis elegans and investigate its underlyirig molecular mechanisms.

Based on relevent theory of prescription and syndrome, to compare the gene expression differences of TLR2, TRAF6, and Faslg with adjuvant arthritis in rat spleen among Wutou decoction, Guizhi Shaoyao Zhimu decoction and Baihu Guizhi decoction.

To investigate the effect and mechanism of emodin on acute intrahepatic cholestasis induced by alpha-naphthylisothiocyanate (ANIT) in rats.